HK1216722A1 - 新雙環溴結構域抑制劑 - Google Patents

新雙環溴結構域抑制劑

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Publication number
HK1216722A1
HK1216722A1 HK16104809.5A HK16104809A HK1216722A1 HK 1216722 A1 HK1216722 A1 HK 1216722A1 HK 16104809 A HK16104809 A HK 16104809A HK 1216722 A1 HK1216722 A1 HK 1216722A1
Authority
HK
Hong Kong
Prior art keywords
bromodomain inhibitors
novel bicyclic
bicyclic bromodomain
novel
inhibitors
Prior art date
Application number
HK16104809.5A
Other languages
English (en)
Inventor
Bryan Cordell Duffy
Shuang Liu
John Frederick Quinn
Ruifang Wang
May Xiaowu Jiang
Gregory Scott Martin
Gregory Steven Wagner
Peter Ronald Young
Original Assignee
Zenith Epigenetics Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zenith Epigenetics Corp filed Critical Zenith Epigenetics Corp
Publication of HK1216722A1 publication Critical patent/HK1216722A1/zh

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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
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