HK1209457A1 - Combined chemical and genetic approaches for generation of induced pluripotent stem cells - Google Patents
Combined chemical and genetic approaches for generation of induced pluripotent stem cellsInfo
- Publication number
- HK1209457A1 HK1209457A1 HK15110187.5A HK15110187A HK1209457A1 HK 1209457 A1 HK1209457 A1 HK 1209457A1 HK 15110187 A HK15110187 A HK 15110187A HK 1209457 A1 HK1209457 A1 HK 1209457A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- generation
- stem cells
- pluripotent stem
- induced pluripotent
- genetic approaches
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0696—Artificially induced pluripotent stem cells, e.g. iPS
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
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- A61P11/08—Bronchodilators
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- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
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- A61P25/00—Drugs for disorders of the nervous system
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- A—HUMAN NECESSITIES
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- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
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- C12N5/0623—Stem cells
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- C12N5/06—Animal cells or tissues; Human cells or tissues
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- C12N5/0625—Epidermal cells, skin cells; Cells of the oral mucosa
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- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
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- C12N2500/00—Specific components of cell culture medium
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- C12N2500/10—Metals; Metal chelators
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- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/08—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from cells of the nervous system
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- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/09—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from epidermal cells, from skin cells, from oral mucosa cells
- C12N2506/094—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from epidermal cells, from skin cells, from oral mucosa cells from keratinocytes
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- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/13—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells
- C12N2506/1307—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells from adult fibroblasts
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- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/28—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from vascular endothelial cells
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- C12N2510/00—Genetically modified cells
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US6995608P | 2008-03-17 | 2008-03-17 | |
US19798608P | 2008-10-31 | 2008-10-31 |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1209457A1 true HK1209457A1 (en) | 2016-04-01 |
Family
ID=41091504
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK11105755.1A HK1151559A1 (zh) | 2008-03-17 | 2011-06-08 | 用於產生誘導多能幹細胞的化學和遺傳學組合方法 |
HK15110187.5A HK1209457A1 (en) | 2008-03-17 | 2015-10-16 | Combined chemical and genetic approaches for generation of induced pluripotent stem cells |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK11105755.1A HK1151559A1 (zh) | 2008-03-17 | 2011-06-08 | 用於產生誘導多能幹細胞的化學和遺傳學組合方法 |
Country Status (16)
Country | Link |
---|---|
US (8) | US9534205B2 (xx) |
EP (3) | EP2955222B1 (xx) |
JP (6) | JP5951254B2 (xx) |
KR (1) | KR101679082B1 (xx) |
CN (2) | CN104694570B (xx) |
AU (1) | AU2009225665B9 (xx) |
BR (1) | BRPI0908708A2 (xx) |
CA (1) | CA2718904C (xx) |
ES (1) | ES2690554T3 (xx) |
HK (2) | HK1151559A1 (xx) |
IL (1) | IL208144B (xx) |
MX (1) | MX2010010165A (xx) |
RU (1) | RU2010139426A (xx) |
SG (4) | SG188904A1 (xx) |
WO (1) | WO2009117439A2 (xx) |
ZA (1) | ZA201006683B (xx) |
Families Citing this family (175)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20110171185A1 (en) * | 1999-06-30 | 2011-07-14 | Klimanskaya Irina V | Genetically intact induced pluripotent cells or transdifferentiated cells and methods for the production thereof |
US7682828B2 (en) * | 2003-11-26 | 2010-03-23 | Whitehead Institute For Biomedical Research | Methods for reprogramming somatic cells |
CA2659945C (en) | 2005-08-03 | 2014-12-16 | Advanced Cell Technology, Inc. | Improved methods of reprogramming animal somatic cells |
KR101441843B1 (ko) | 2005-10-18 | 2014-09-17 | 내셔날 쥬이쉬 헬스 | 조건부 불멸화 장기 줄기 세포 및 상기 세포의 제조 및 사용 방법 |
EP2208786B1 (en) * | 2005-12-13 | 2018-08-01 | Kyoto University | Nuclear reprogramming factor |
US8278104B2 (en) * | 2005-12-13 | 2012-10-02 | Kyoto University | Induced pluripotent stem cells produced with Oct3/4, Klf4 and Sox2 |
US20090227032A1 (en) * | 2005-12-13 | 2009-09-10 | Kyoto University | Nuclear reprogramming factor and induced pluripotent stem cells |
US8129187B2 (en) | 2005-12-13 | 2012-03-06 | Kyoto University | Somatic cell reprogramming by retroviral vectors encoding Oct3/4. Klf4, c-Myc and Sox2 |
WO2008124133A1 (en) | 2007-04-07 | 2008-10-16 | Whitehead Institute For Biomedical Research | Reprogramming of somatic cells |
JP2008307007A (ja) * | 2007-06-15 | 2008-12-25 | Bayer Schering Pharma Ag | 出生後のヒト組織由来未分化幹細胞から誘導したヒト多能性幹細胞 |
US9213999B2 (en) * | 2007-06-15 | 2015-12-15 | Kyoto University | Providing iPSCs to a customer |
US20140342984A1 (en) * | 2007-10-19 | 2014-11-20 | Robert G. Matheny | Compositions for Regenerating Defective or Absent Myocardium |
JP5951254B2 (ja) | 2008-03-17 | 2016-07-13 | ザ スクリプス リサーチ インスティテュート | 人工多能性幹細胞を作製するための化学的手法と遺伝的手法の組み合わせ法 |
WO2009126251A2 (en) * | 2008-04-07 | 2009-10-15 | Nupotential, Inc. | Reprogramming a cell by inducing a pluripotent gene through use of an hdac modulator |
ES2722198T3 (es) * | 2008-05-02 | 2019-08-08 | Univ Kyoto | Método de reprogramación nuclear |
EP2285832B1 (en) | 2008-05-16 | 2020-08-26 | Taiga Biotechnologies, Inc. | Antibodies and processes for preparing the same |
JP2011524174A (ja) | 2008-06-13 | 2011-09-01 | ホワイトヘッド・インスティテュート・フォー・バイオメディカル・リサーチ | 細胞のプログラミングおよび再プログラミング |
JP5762286B2 (ja) | 2008-07-21 | 2015-08-12 | タイガ バイオテクノロジーズ,インク. | 分化無核細胞、及び該無核細胞の作成方法 |
US8298825B1 (en) * | 2008-08-25 | 2012-10-30 | The General Hospital Corporation | TGF-beta receptor inhibitors to enhance direct reprogramming |
AU2009285547B2 (en) | 2008-08-28 | 2012-05-31 | Taiga Biotechnologies, Inc. | Modulators of MYC, methods of using the same, and methods of identifying agents that modulate MYC |
WO2010068955A2 (en) | 2008-12-13 | 2010-06-17 | Dna Microarray | MICROENVIRONMENT NICHE ASSAY FOR CiPS SCREENING |
SG172160A1 (en) | 2008-12-17 | 2011-07-28 | Scripps Research Inst | Generation and maintenance of stem cells |
AU2009329893A1 (en) * | 2008-12-23 | 2011-06-30 | Vivoscript, Inc. | Compositions and methods for re-programming cells without genetic modification |
US20120128655A1 (en) * | 2009-04-03 | 2012-05-24 | The Mclean Hospital Corporation | Induced pluripotent stem cells |
US9109245B2 (en) | 2009-04-22 | 2015-08-18 | Viacyte, Inc. | Cell compositions derived from dedifferentiated reprogrammed cells |
US9005975B2 (en) | 2009-05-29 | 2015-04-14 | Kyoto University | Method for selecting clone of induced pluripotent stem cells |
US8709805B2 (en) * | 2009-08-07 | 2014-04-29 | Kyoto University | Canine iPS cells and method of producing same |
AU2014250681B2 (en) * | 2009-10-16 | 2016-12-15 | The Scripps Research Institute | Induction of pluripotent cells |
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