HK1184781A1 - 凋亡信號調節激酶抑制劑 - Google Patents

凋亡信號調節激酶抑制劑

Info

Publication number
HK1184781A1
HK1184781A1 HK13112156.0A HK13112156A HK1184781A1 HK 1184781 A1 HK1184781 A1 HK 1184781A1 HK 13112156 A HK13112156 A HK 13112156A HK 1184781 A1 HK1184781 A1 HK 1184781A1
Authority
HK
Hong Kong
Prior art keywords
kinase inhibitors
apoptosis signal
regulating kinase
regulating
apoptosis
Prior art date
Application number
HK13112156.0A
Other languages
English (en)
Inventor
Britton Corkey
Gregory Notte
Jeff Zablocki
Original Assignee
Gilead Sciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gilead Sciences Inc filed Critical Gilead Sciences Inc
Publication of HK1184781A1 publication Critical patent/HK1184781A1/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
HK13112156.0A 2010-07-02 2013-10-29 凋亡信號調節激酶抑制劑 HK1184781A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US36108010P 2010-07-02 2010-07-02
PCT/US2011/042694 WO2012003387A1 (en) 2010-07-02 2011-06-30 Apoptosis signal-regulating kinase inhibitors

Publications (1)

Publication Number Publication Date
HK1184781A1 true HK1184781A1 (zh) 2014-01-30

Family

ID=44318106

Family Applications (1)

Application Number Title Priority Date Filing Date
HK13112156.0A HK1184781A1 (zh) 2010-07-02 2013-10-29 凋亡信號調節激酶抑制劑

Country Status (18)

Country Link
US (3) US8440665B2 (zh)
EP (1) EP2588475B1 (zh)
JP (1) JP5705314B2 (zh)
KR (1) KR101759759B1 (zh)
CN (1) CN102985418B (zh)
AU (1) AU2011272782B2 (zh)
BR (1) BR112012033715A2 (zh)
CA (1) CA2802743C (zh)
EA (1) EA023040B1 (zh)
ES (1) ES2543428T3 (zh)
HK (1) HK1184781A1 (zh)
IL (2) IL223556A (zh)
MX (1) MX2012015105A (zh)
NZ (1) NZ604831A (zh)
PL (1) PL2588475T3 (zh)
PT (1) PT2588475E (zh)
SI (1) SI2588475T1 (zh)
WO (1) WO2012003387A1 (zh)

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Publication number Publication date
AU2011272782B2 (en) 2014-11-27
EA201291273A1 (ru) 2013-06-28
US8927582B2 (en) 2015-01-06
PT2588475E (pt) 2015-09-08
JP2013530240A (ja) 2013-07-25
CN102985418B (zh) 2015-09-09
KR101759759B1 (ko) 2017-07-19
US8440665B2 (en) 2013-05-14
IL247405A0 (en) 2016-11-30
US20130203819A1 (en) 2013-08-08
ES2543428T3 (es) 2015-08-19
EP2588475A1 (en) 2013-05-08
JP5705314B2 (ja) 2015-04-22
KR20130129890A (ko) 2013-11-29
USRE48150E1 (en) 2020-08-11
MX2012015105A (es) 2013-05-28
AU2011272782A1 (en) 2013-01-10
CN102985418A (zh) 2013-03-20
IL223556A (en) 2016-08-31
EA023040B1 (ru) 2016-04-29
WO2012003387A1 (en) 2012-01-05
PL2588475T3 (pl) 2015-10-30
CA2802743A1 (en) 2012-01-05
EP2588475B1 (en) 2015-05-20
BR112012033715A2 (pt) 2016-11-22
CA2802743C (en) 2019-05-07
SI2588475T1 (sl) 2015-12-31
NZ604831A (en) 2014-12-24
US20120004267A1 (en) 2012-01-05

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