HK1150310A1 - - Google Patents

Info

Publication number
HK1150310A1
HK1150310A1 HK11104407.6A HK11104407A HK1150310A1 HK 1150310 A1 HK1150310 A1 HK 1150310A1 HK 11104407 A HK11104407 A HK 11104407A HK 1150310 A1 HK1150310 A1 HK 1150310A1
Authority
HK
Hong Kong
Application number
HK11104407.6A
Inventor
Hisashi Shibata
Kodo Shikata
Akira Inomata
Kogyoku Shin
Taro Terauchi
Yoshinori Takahashi
Minako Hashizume
Kunitoshi Takeda
Original Assignee
Eisai R&D Man Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eisai R&D Man Co Ltd filed Critical Eisai R&D Man Co Ltd
Publication of HK1150310A1 publication Critical patent/HK1150310A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D513/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32Alcohol-abuse
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Addiction (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
HK11104407.6A 2008-04-15 2011-05-03 HK1150310A1 (xx)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US4508408P 2008-04-15 2008-04-15
JP2008106080 2008-04-15
PCT/JP2009/057270 WO2009128383A1 (ja) 2008-04-15 2009-04-09 3-フェニルピラゾロ[5,1-b]チアゾール化合物

Publications (1)

Publication Number Publication Date
HK1150310A1 true HK1150310A1 (xx) 2011-11-25

Family

ID=41164535

Family Applications (2)

Application Number Title Priority Date Filing Date
HK11104407.6A HK1150310A1 (xx) 2008-04-15 2011-05-03
HK11105942.5A HK1151797A1 (xx) 2008-04-15 2011-06-13

Family Applications After (1)

Application Number Title Priority Date Filing Date
HK11105942.5A HK1151797A1 (xx) 2008-04-15 2011-06-13

Country Status (29)

Country Link
US (1) US8431603B2 (xx)
EP (1) EP2266990B1 (xx)
JP (1) JP4654325B2 (xx)
KR (1) KR101601994B1 (xx)
CN (1) CN102007133B (xx)
AR (1) AR071655A1 (xx)
AU (1) AU2009237050B2 (xx)
BR (1) BRPI0911659B8 (xx)
CA (1) CA2721670C (xx)
CL (1) CL2009000896A1 (xx)
CY (1) CY1113484T1 (xx)
DK (1) DK2266990T3 (xx)
ES (1) ES2396126T3 (xx)
HK (2) HK1150310A1 (xx)
HR (1) HRP20121021T1 (xx)
IL (1) IL208393A (xx)
MX (1) MX2010011089A (xx)
MY (1) MY152687A (xx)
NZ (1) NZ588376A (xx)
PE (1) PE20091890A1 (xx)
PL (1) PL2266990T3 (xx)
PT (1) PT2266990E (xx)
RS (1) RS52561B (xx)
RU (1) RU2482120C2 (xx)
SI (1) SI2266990T1 (xx)
TW (1) TW201004964A (xx)
UA (1) UA101836C2 (xx)
WO (1) WO2009128383A1 (xx)
ZA (1) ZA201006764B (xx)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2721670C (en) 2008-04-15 2013-09-10 Eisai R&D Management Co., Ltd. 3-phenylpyrazolo[5,1-b]thiazole compound
JPWO2011043387A1 (ja) * 2009-10-08 2013-03-04 エーザイ・アール・アンド・ディー・マネジメント株式会社 ピラゾロオキサゾール化合物
AR078521A1 (es) 2009-10-08 2011-11-16 Eisai R&D Man Co Ltd Compuesto pirazolotiazol
CN102020587A (zh) * 2010-11-25 2011-04-20 大连凯飞精细化工有限公司 2-甲氧基-4-氰基苯甲醛的合成方法
TWI679205B (zh) * 2014-09-02 2019-12-11 日商日本新藥股份有限公司 吡唑并噻唑化合物及醫藥
CN115010621B (zh) * 2022-07-21 2023-11-03 山东百启生物医药有限公司 一种4-溴-3-甲基苯甲腈的合成方法

Family Cites Families (92)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US224974A (en) 1880-02-24 wheeler
JPS5320360B2 (xx) 1973-05-30 1978-06-26
JPS51141896A (en) 1975-05-31 1976-12-07 Sankyo Co Ltd Process for preparing fused ring triazoropyrimidine derivatives
EP0068378B1 (en) 1981-06-26 1986-03-05 Schering Corporation Novel imidazo(1,2-a)pyridines and pyrazines, processes for their preparation and pharmaceutical compositions containing them
US4596872A (en) 1985-06-05 1986-06-24 Schering A.G. Imidazo[1,2-a]pyridines, and process for their preparation
FR2594438B1 (fr) 1986-02-14 1990-01-26 Labaz Sanofi Nv Derives d'indolizine, leur procede de preparation ainsi que les compositions en contenant
US5190862A (en) 1987-04-01 1993-03-02 Boehringer Mannheim Gmbh Chromogenic compounds and the use thereof as enzyme substrates
US5179103A (en) 1987-06-15 1993-01-12 Fujisawa Pharmaceutical Company, Ltd. Pharmaceutically useful pyrazolopyridines
US4925849A (en) 1987-06-15 1990-05-15 Fujisawa Pharmaceutical Company, Ltd. Pharmaceutically useful pyrazolopyridines
FR2619818B1 (fr) 1987-09-01 1990-01-12 Sanofi Sa Imidazo (1,2-b) pyridazines, procede pour leur preparation et compositions pharmaceutiques les contenant
US5338743A (en) 1988-06-06 1994-08-16 Fujisawa Pharmaceutical Co., Ltd. New use of the adenosine antagonist
US5155114A (en) 1989-01-23 1992-10-13 Fujisawa Pharmaceutical Company, Ltd. Method of treatment using pyrazolopyridine compound
JPH0276880A (ja) 1988-06-16 1990-03-16 Sankyo Co Ltd 悪液質改善治療剤
ES2055073T3 (es) 1988-07-19 1994-08-16 Du Pont Feniltriazolopirimidinas sustituidas herbicidas.
US5127936A (en) 1988-07-19 1992-07-07 E. I. Du Pont De Nemours And Company Substituted phenyltriazolopyrimidine herbicides
CA1330079C (en) 1988-10-13 1994-06-07 Michihiko Tsujitani Pyrrolo (3,2-e)pyrazolo(1,5-a)pyrimidine derivative and medicine comprising the same
JPH0688999B2 (ja) 1988-10-13 1994-11-09 ポーラ化成工業株式会社 ピロロ〔3,2―e〕ピラゾロ〔1,5―a〕ピリミジン誘導体およびこれを含有する医薬
JPH085790B2 (ja) 1988-11-11 1996-01-24 杏林製薬株式会社 記憶障害改善薬
GB8901423D0 (en) 1989-01-23 1989-03-15 Fujisawa Pharmaceutical Co Pyrazolopyridine compound and processes for preparation thereof
US5231818A (en) * 1989-04-04 1993-08-03 Newman Frederica C Equestrian training aid
DE3942357A1 (de) 1989-12-21 1991-06-27 Boehringer Mannheim Gmbh 3-aminopyrazolo-heterocyclen, deren verwendung zur bestimmung von wasserstoffperoxid, wasserstoffperoxid-bildenden systemen, peroxidase, peroxidatisch wirksamen substanzen oder von elektronenreichen aromatischen verbindungen, entsprechende bestimmungsverfahren und hierfuer geeignete mittel
DE3942356A1 (de) 1989-12-21 1991-06-27 Boehringer Mannheim Gmbh Verwendung von 1-arylsemicarbaziden zur stabilisierung von enzymsubstraten, entsprechende verfahren und diagnostisches mittel enthaltend einen solchen stabilisator
DE3942355A1 (de) 1989-12-21 1991-06-27 Boehringer Mannheim Gmbh N- und o-substituierte aminophenolderivate, zwischenprodukte zu deren herstellung, deren verwendung als hydrolasesubstrate, ein entsprechendes bestimmungsverfahren und hierfuer geeignetes diagnostisches mittel
EP0497258B1 (en) 1991-01-29 2002-01-02 Fujisawa Pharmaceutical Co., Ltd. Use of adenosine antagonists in the prevention and treatment of pancreatitis and ulcer
JP3295149B2 (ja) 1991-12-26 2002-06-24 ポーラ化成工業株式会社 ピロロ[3,2−e]ピラゾロ[1,5−a]ピリミジン誘導体
FR2687675B1 (fr) 1992-01-31 1997-04-18 Roussel Uclaf Nouveaux derives bicycliques de la pyridine, leur procede de preparation, les nouveaux intermediaires obtenus, leur application a titre de medicaments et les compositions pharmaceutiques les renfermant.
JPH05271338A (ja) 1992-03-27 1993-10-19 Nippon Zeon Co Ltd 二置換ジフェニルアセチレン系重合体
AU4293393A (en) 1992-06-17 1994-01-04 Upjohn Company, The Pyridino-, pyrrolidino- and azepino-substituted oximes useful as anti-atherosclerosis and anti-hypercholesterolemic agents
DK0674631T3 (da) 1992-12-17 2000-04-10 Pfizer Substituerede pyrazoler som CRF-antogonister
KR0170567B1 (ko) 1992-12-17 1999-02-18 알렌 제이. 스피겔 부신피질자극호르몬-유리 인자 길항물질 활성을 갖는 피라졸 및 피라졸로피리미딘
TW370529B (en) 1992-12-17 1999-09-21 Pfizer Pyrazolopyrimidines
US6765008B1 (en) 1992-12-17 2004-07-20 Pfizer Inc Pyrrolopyrimidines as CRF antagonists
TW336932B (en) 1992-12-17 1998-07-21 Pfizer Amino-substituted pyrazoles
FR2701708B1 (fr) 1993-02-19 1995-05-19 Sanofi Elf Dérivés de 2-amido-4-phénylthiazoles polysubstitués, procédé de préparation, composition pharmaceutique et utilisation de ces dérivés pour la préparation d'un médicament.
DE4311460A1 (de) 1993-04-08 1994-10-13 Boehringer Mannheim Gmbh Verfahren zur kolorimetrischen Bestimmung eines Analyten mittels Benzylalkoholdehydrogenase und einem chromogenen Redoxindikator
JP3398152B2 (ja) 1993-10-12 2003-04-21 ブリストル‐マイヤーズ・スクイブ・ファーマ・カンパニー 1n−アルキル−n−アリールピリミジンアミンおよびその誘導体
FR2714059B1 (fr) 1993-12-21 1996-03-08 Sanofi Elf Dérivés amino ramifiés du thiazole, leurs procédés de préparation et les compositions pharmaceutiques qui les contiennent.
JP2891544B2 (ja) 1994-06-16 1999-05-17 ファイザー・インコーポレーテッド ピラゾロおよびピロロピリジン類
JP3508033B2 (ja) 1994-11-08 2004-03-22 旭電化工業株式会社 エポキシ樹脂組成物
US5955613A (en) 1995-10-13 1999-09-21 Neurogen Corporation Certain pyrrolopyridine derivatives; novel CRF1 specific ligands
EP0778277B1 (en) 1995-12-08 2003-06-25 Pfizer Inc. Substituted heterocyclic derivatives as CRF antagonists
US6664261B2 (en) 1996-02-07 2003-12-16 Neurocrine Biosciences, Inc. Pyrazolopyrimidines as CRF receptor antagonists
ATE208395T1 (de) 1996-02-07 2001-11-15 Janssen Pharmaceutica Nv Thiophenopyrimidine
DE69736513T2 (de) 1996-02-07 2007-04-05 Neurocrine Biosciences, Inc., San Diego Pyrazolopyrimidine als crf rezeptor-antagonisten
ZA973884B (en) 1996-05-23 1998-11-06 Du Pont Merck Pharma Tetrahydropteridines and pyridylpiperazines for treatment of neurological disorders
US6022978A (en) 1996-06-11 2000-02-08 Pfizer Inc. Benzimidazole derivatives
AU735401B2 (en) 1996-08-28 2001-07-05 Pfizer Inc. Substituted 6,5-hetero-bicyclic derivatives
US20010007867A1 (en) * 1999-12-13 2001-07-12 Yuhpyng L. Chen Substituted 6,5-hetero-bicyclic derivatives
JPH10218881A (ja) 1997-02-03 1998-08-18 Pola Chem Ind Inc 新規なピロロピラゾロピリミジン誘導体
JP2001511813A (ja) 1997-02-18 2001-08-14 ニューロクライン バイオサイエンシーズ,インコーポレイテッド Crfレセプターアンタゴニストおよびそれらに関連する方法
JPH1143434A (ja) 1997-05-30 1999-02-16 Pola Chem Ind Inc カリウムチャンネル開口薬
AU746706B2 (en) 1997-07-03 2002-05-02 Du Pont Pharmaceuticals Company Imidazopyrimidines and imidazopyridines for the treatment of neurological disorders
EP0937081A1 (en) 1997-08-22 1999-08-25 Du Pont Pharmaceuticals Company NITROGEN SUBSTITUTED IMIDAZO 4,5-c]PYRAZOLES AS CORTICOTROPIN RELEASING HORMONE ANTAGONISTS
MY153569A (en) 1998-01-20 2015-02-27 Mitsubishi Tanabe Pharma Corp Inhibitors of ?4 mediated cell adhesion
AU2298599A (en) 1998-02-04 1999-08-23 Nissan Chemical Industries Ltd. Pyridine derivatives fused with azole and herbicide
US6365589B1 (en) 1998-07-02 2002-04-02 Bristol-Myers Squibb Pharma Company Imidazo-pyridines, -pyridazines, and -triazines as corticotropin releasing factor antagonists
US6271380B1 (en) 1998-12-30 2001-08-07 Dupont Pharmaceuticals Company 1H-imidazo[4,5-d]pyridazin-7-ones, 3H-imidazo-[4,5-c]pyridin-4-ones and corresponding thiones as corticotropin releasing factor (CRF) receptor ligands
WO2000059908A2 (en) 1999-04-06 2000-10-12 Du Pont Pharmaceuticals Company Pyrazolopyrimidines as crf antagonists
AU4331500A (en) 1999-04-06 2000-10-23 Du Pont Pharmaceuticals Company Pyrazolotriazines as crf antagonists
JP3795305B2 (ja) 1999-07-19 2006-07-12 田辺製薬株式会社 医薬組成物
ATE413403T1 (de) 1999-10-08 2008-11-15 Gruenenthal Gmbh Bicyclische imidazo-5-yl-aminderivate
SE9903760D0 (sv) 1999-10-18 1999-10-18 Astra Ab New compounds
EP1218380B1 (de) 1999-10-08 2003-12-17 Grünenthal GmbH Am sechsring substituierte, bicyclische imidazo-3-yl-aminderivate
CA2382919C (en) 1999-10-08 2008-12-09 Gruenenthal Gmbh Bicyclic imidazo-3-yl-amine derivatives
DE19948434A1 (de) 1999-10-08 2001-06-07 Gruenenthal Gmbh Substanzbibliothek enthaltend bicyclische Imidazo-5-amine und/oder bicyclische Imidazo-3-amine
FR2801308B1 (fr) 1999-11-19 2003-05-09 Oreal COMPOSITIONS DE TEINTURE DE FIBRES KERATINIQUES CONTENANT DE DES 3-AMINO PYRAZOLO-[1,(-a]-PYRIDINES, PROCEDE DE TEINTURE, NOUVELLES 3-AMINO PYRAZOLO-[1,5-a]-PYRIDINES
EP1244666A1 (en) 1999-12-17 2002-10-02 Bristol-Myers Squibb Pharma Company Imidazopyrimidinyl and imidazopyridinyl derivatives
CA2419626A1 (en) 2000-07-14 2002-01-24 Rajagopal Bakthavatachalam Imidazo¬1,2-a|pyrazines for the treatment of neurological disorders
MY129000A (en) 2000-08-31 2007-03-30 Tanabe Seiyaku Co INHIBITORS OF a4 MEDIATED CELL ADHESION
JP3617433B2 (ja) 2000-09-05 2005-02-02 株式会社デンソー 駆動回路
RU2003126188A (ru) 2001-01-26 2005-03-27 Бристол-Маерс Сквибб Компани (Us) Имидазолильные производные как ингибиторы кортикотропин-рилизинг фактора
TWI312347B (en) 2001-02-08 2009-07-21 Eisai R&D Man Co Ltd Bicyclic nitrogen-containing condensed ring compounds
DK1390340T3 (en) 2001-04-24 2017-05-15 Massachusetts Inst Technology Copper-catalyzed formation of carbon-heteroatom and carbon-carbon bonds
CA2443802C (en) 2001-04-27 2010-04-13 Eisai Co., Ltd. Pyrazolo[1,5-a]pyridines and medicines containing the same
JP4631228B2 (ja) 2001-07-31 2011-02-16 株式会社豊田自動織機 ピストン式圧縮機における防振構造
AU2002318237A1 (en) 2001-12-19 2003-07-09 Flexitral, Inc. Improved citral derivatives
MY140707A (en) 2002-02-28 2010-01-15 Mitsubishi Tanabe Pharma Corp Process for preparing a phenylalanine derivative and intermediates thereof
CA2478715A1 (en) 2002-03-13 2003-09-25 Pharmacia & Upjohn Company Novel pyrazolo [1,5-a]pyridine derivatives and their use as neurotransmitter modulators
JP2005531347A (ja) 2002-07-01 2005-10-20 アミジッチ,オグニエン 試験人物の認知または感覚運動の能力もしくは才能を評価するために使用されるデータを生成するための方法
JP2004053678A (ja) 2002-07-16 2004-02-19 Toyobo Co Ltd Irアブレーション用積層体
EP1555265B1 (en) 2002-10-22 2009-03-25 Eisai R&D Management Co., Ltd. 7-phenyl pyrazolopyridine compounds
US7176216B2 (en) 2002-10-22 2007-02-13 Eisai Co., Ltd. 7-phenylpyrazolopyridine compounds
EP1697369A1 (en) 2003-12-22 2006-09-06 SB Pharmco Puerto Rico Inc Crf receptor antagonists and methods relating thereto
WO2005079868A2 (en) 2004-02-13 2005-09-01 Sb Pharmco Puerto Rico Inc Crf receptor antagonists, their preparations, their pharmaceutical composition and their uses
JP4832743B2 (ja) 2004-03-29 2011-12-07 ケンブリッジユニバーシティテクニカルサービスリミテッド 化合物の合成方法および合成反応触媒
JP4520215B2 (ja) 2004-04-30 2010-08-04 日油株式会社 分子量が制御された置換ジフェニルアセチレン重合体の製造方法
GB0519957D0 (en) 2005-09-30 2005-11-09 Sb Pharmco Inc Chemical compound
US8088779B2 (en) 2005-09-30 2012-01-03 Smithkline Beecham (Cork) Limited Pyrazolo [1,5-alpha] pyrimidinyl derivatives useful as corticotropin-releasing factor (CRF) receptor antagonists
CA2721670C (en) 2008-04-15 2013-09-10 Eisai R&D Management Co., Ltd. 3-phenylpyrazolo[5,1-b]thiazole compound
US7994203B2 (en) 2008-08-06 2011-08-09 Novartis Ag Organic compounds
JP2010235929A (ja) 2009-03-09 2010-10-21 Sumitomo Chemical Co Ltd 重合体
TWI358017B (en) 2009-12-17 2012-02-11 Askey Computer Corp Electronic device loading base

Also Published As

Publication number Publication date
CA2721670A1 (en) 2009-10-22
MY152687A (en) 2014-10-31
US8431603B2 (en) 2013-04-30
WO2009128383A1 (ja) 2009-10-22
ZA201006764B (en) 2012-03-28
ES2396126T3 (es) 2013-02-19
BRPI0911659A2 (pt) 2015-10-13
BRPI0911659B1 (pt) 2020-08-25
CN102007133B (zh) 2013-06-12
AU2009237050A1 (en) 2009-10-22
KR20110002007A (ko) 2011-01-06
CY1113484T1 (el) 2016-06-22
EP2266990A4 (en) 2011-08-03
IL208393A0 (en) 2010-12-30
DK2266990T3 (da) 2013-01-07
JP4654325B2 (ja) 2011-03-16
EP2266990B1 (en) 2012-09-26
HRP20121021T1 (hr) 2013-01-31
NZ588376A (en) 2011-06-30
RS52561B (en) 2013-04-30
AU2009237050B2 (en) 2013-04-11
SI2266990T1 (sl) 2013-01-31
PT2266990E (pt) 2012-12-27
TW201004964A (en) 2010-02-01
US20090259049A1 (en) 2009-10-15
KR101601994B1 (ko) 2016-03-17
RU2010146240A (ru) 2012-05-20
UA101836C2 (xx) 2013-05-13
PE20091890A1 (es) 2009-12-20
CL2009000896A1 (es) 2010-04-16
CN102007133A (zh) 2011-04-06
RU2482120C2 (ru) 2013-05-20
EP2266990A1 (en) 2010-12-29
BRPI0911659B8 (pt) 2021-05-25
CA2721670C (en) 2013-09-10
IL208393A (en) 2013-08-29
JPWO2009128383A1 (ja) 2011-08-04
PL2266990T3 (pl) 2013-03-29
AR071655A1 (es) 2010-07-07
MX2010011089A (es) 2010-11-05
HK1151797A1 (xx) 2012-02-10

Similar Documents

Publication Publication Date Title
BR112016019572A2 (xx)
BRPI0917573A2 (xx)
BRPI0918697A2 (xx)
BRPI0920750A2 (xx)
BRPI0919470A2 (xx)
BRPI0922455A2 (xx)
BRPI0917618A8 (xx)
BRPI0923734A2 (xx)
BRPI0922669A2 (xx)
BRPI0919811A2 (xx)
BRPI0920914A2 (xx)
BRPI0922550A2 (xx)
BRPI0916284A2 (xx)
BRPI0914852A2 (xx)
CH2347250H2 (xx)
AR073287B1 (xx)
BRPI0919477A2 (xx)
BRPI0923127A (xx)
BRPI0923137A2 (xx)
BRMU8803485U8 (xx)
CN300880970S (zh) 户外装饰物(火05)
CN300855601S (zh) 圣诞装饰品(月亮k28b-35)
CN300889585S (zh) 笔(07)
CN300892525S (zh) 凳子(0801)
CN300889571S (zh) 文件袋(内外层、双层、双拉链、网孔)

Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20170409