ATE208395T1 - Thiophenopyrimidine - Google Patents

Thiophenopyrimidine

Info

Publication number
ATE208395T1
ATE208395T1 AT97904368T AT97904368T ATE208395T1 AT E208395 T1 ATE208395 T1 AT E208395T1 AT 97904368 T AT97904368 T AT 97904368T AT 97904368 T AT97904368 T AT 97904368T AT E208395 T1 ATE208395 T1 AT E208395T1
Authority
AT
Austria
Prior art keywords
thiophenopyrimidines
Prior art date
Application number
AT97904368T
Other languages
English (en)
Inventor
Chen Chen
Thomas R Webb
James R Mccarthy
Terence J Moran
Original Assignee
Janssen Pharmaceutica Nv
Neurocrine Biosciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv, Neurocrine Biosciences Inc filed Critical Janssen Pharmaceutica Nv
Application granted granted Critical
Publication of ATE208395T1 publication Critical patent/ATE208395T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
    • A61P5/04—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin for decreasing, blocking or antagonising the activity of the hypothalamic hormones
AT97904368T 1996-02-07 1997-01-30 Thiophenopyrimidine ATE208395T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US1127496P 1996-02-07 1996-02-07
US2768996P 1996-10-08 1996-10-08
PCT/EP1997/000457 WO1997029110A1 (en) 1996-02-07 1997-01-30 Thiophenopyrimidines

Publications (1)

Publication Number Publication Date
ATE208395T1 true ATE208395T1 (de) 2001-11-15

Family

ID=26682201

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97904368T ATE208395T1 (de) 1996-02-07 1997-01-30 Thiophenopyrimidine

Country Status (17)

Country Link
US (2) US6255310B1 (de)
EP (1) EP0882051B1 (de)
JP (1) JP2000504678A (de)
KR (1) KR19990067390A (de)
AR (1) AR005731A1 (de)
AT (1) ATE208395T1 (de)
CA (1) CA2233307A1 (de)
DE (1) DE69708059T2 (de)
DK (1) DK0882051T3 (de)
ES (1) ES2167710T3 (de)
ID (1) ID15904A (de)
MY (1) MY119118A (de)
NO (1) NO981356L (de)
NZ (1) NZ330118A (de)
PT (1) PT882051E (de)
TW (1) TW448178B (de)
WO (1) WO1997029110A1 (de)

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US7094782B1 (en) 1996-07-24 2006-08-22 Bristol-Myers Squibb Company Azolo triazines and pyrimidines
US6313124B1 (en) 1997-07-23 2001-11-06 Dupont Pharmaceuticals Company Tetrazine bicyclic compounds
US6060478A (en) * 1996-07-24 2000-05-09 Dupont Pharmaceuticals Azolo triazines and pyrimidines
US6191131B1 (en) 1997-07-23 2001-02-20 Dupont Pharmaceuticals Company Azolo triazines and pyrimidines
US6124289A (en) * 1996-07-24 2000-09-26 Dupont Pharmaceuticals Co. Azolo triazines and pyrimidines
CN1280580A (zh) 1997-11-11 2001-01-17 辉瑞产品公司 用作抗癌药的噻吩并嘧啶和噻吩并吡啶衍生物
US6187777B1 (en) 1998-02-06 2001-02-13 Amgen Inc. Compounds and methods which modulate feeding behavior and related diseases
DE19837387A1 (de) * 1998-08-18 2000-02-24 Aventis Res & Tech Gmbh & Co 3'-Desoxypentopyranosyl-Nucleinsäure, ihre Herstellung und Verwendung
US6432989B1 (en) 1999-08-27 2002-08-13 Pfizer Inc Use of CRF antagonists to treat circadian rhythm disorders
EA200200424A1 (ru) 1999-09-30 2002-12-26 Ньюроджен Корпорейшн Некоторые гетероциклы, замещенные алкилендиамином
CO5271670A1 (es) 1999-10-29 2003-04-30 Pfizer Prod Inc Antagonistas del factor de liberacion de corticitropina y composiciones relacionadas
TWI271406B (en) 1999-12-13 2007-01-21 Eisai Co Ltd Tricyclic condensed heterocyclic compounds, preparation method of the same and pharmaceuticals comprising the same
ATE277933T1 (de) 2000-06-06 2004-10-15 Pfizer Prod Inc Thiophenverbindungen zur verwendung als antikrebsmittel
US6503914B1 (en) 2000-10-23 2003-01-07 Board Of Regents, The University Of Texas System Thienopyrimidine-based inhibitors of the Src family
TWI312347B (en) 2001-02-08 2009-07-21 Eisai R&D Man Co Ltd Bicyclic nitrogen-containing condensed ring compounds
CA2443802C (en) 2001-04-27 2010-04-13 Eisai Co., Ltd. Pyrazolo[1,5-a]pyridines and medicines containing the same
US7285557B2 (en) * 2001-10-15 2007-10-23 Smithkline Beecham P.L.C. Pyrimidinones as melanin concentrating hormone receptor 1
US6872827B2 (en) 2002-04-26 2005-03-29 Chembridge Research Laboratories, Inc. Somatostatin analogue compounds
US20100189797A1 (en) 2002-06-10 2010-07-29 Julien Mendlewicz Oral antidepressant formulation
US7671047B2 (en) * 2002-06-19 2010-03-02 Sanofi-Aventis Deutschland Gmbh Cationically substituted diphenylazetidinones, process for their preparation, medicaments comprising these compounds, and their use
US7176216B2 (en) 2002-10-22 2007-02-13 Eisai Co., Ltd. 7-phenylpyrazolopyridine compounds
RU2327699C2 (ru) 2002-10-22 2008-06-27 Эйсай Ар Энд Ди Менеджмент Ко., Лтд. Соединения 7-фенилпиразолопиридина
US20060071832A1 (en) * 2002-10-29 2006-04-06 Zvi Regev Instantaneous phase digitizer
US20050001673A1 (en) * 2002-10-29 2005-01-06 Zvi Regev Direct digital frequency modulation / phase modulation decoder
US20060024661A1 (en) * 2003-07-30 2006-02-02 The Regents Of The University Of California Modulation of CRF potentiation of NMDA receptor currents via CRF receptor 2
CA2552503C (en) 2004-01-06 2011-09-13 Taisho Pharmaceutical Co., Ltd. Pyrrolopyrimidine and pyrrolotriazine derivatives
RU2006128580A (ru) 2004-01-06 2008-02-20 Тайсо Фармасьютикал Ко., Лтд. (Jp) Производные тиенопиримидина и тиенопиридина, замещенные циклической аминогруппой
CN1980957A (zh) 2004-03-23 2007-06-13 比奥根艾迪克Ma公司 受体偶联剂及其治疗用途
WO2005118810A1 (en) 2004-06-03 2005-12-15 Athlomics Pty Ltd Agents and methods for diagnosing stress
JP2007161585A (ja) 2004-06-25 2007-06-28 Taisho Pharmaceut Co Ltd 環状アミノ基で置換されているピロロピリミジン及びピロロピリジン誘導体
JP5089395B2 (ja) 2004-10-29 2012-12-05 バイオクライスト ファーマシューティカルズ， インコーポレイテッド 治療用フロピリミジンおよびチエノピリミジン
EP2537520A1 (de) 2005-03-29 2012-12-26 Biocryst Pharmaceuticals, Inc. Hepatits-C-Therapien
WO2008082839A2 (en) * 2006-12-29 2008-07-10 Abbott Laboratories Pim kinase inhibitors as cancer chemotherapeutics
NZ588376A (en) 2008-04-15 2011-06-30 Eisai R&D Man Co Ltd 3-phenylpyrazolo[5,1-b]thiazole compound having antagonism against corticotropin-releasing factor (CRF) receptor
AR078521A1 (es) 2009-10-08 2011-11-16 Eisai R&D Man Co Ltd Compuesto pirazolotiazol
WO2017047090A1 (ja) 2015-09-18 2017-03-23 日本電気株式会社 指紋撮像システム、指紋撮像装置、画像処理装置、指紋撮像方法、及び記録媒体
SG11201804901WA (en) 2015-12-22 2018-07-30 SHY Therapeutics LLC Compounds for the treatment of cancer and inflammatory disease
EA201992780A1 (ru) 2017-06-21 2020-06-02 ШАЙ ТЕРАПЬЮТИКС ЭлЭлСи Соединения, которые взаимодействуют с суперсемейством ras, для лечения рака, воспалительных заболеваний, ras-опатий и фиброзного заболевания
CN110590807B (zh) * 2019-10-09 2022-01-07 陕西理工大学 一种噻吩并[3,2-d]嘧啶类衍生物及其应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2121950A1 (en) * 1971-05-04 1972-11-23 Dr. Karl Thomae Gmbh, 7950 Biberach Thieno(3,2-d)pyrimidine derivs - with thrombocyte aggregation inhibiting activity
EP0071227B1 (de) * 1981-07-31 1987-11-11 Sloan-Kettering Institute For Cancer Research Beta-Glycosyl C-Nucleoside mit anti-leukemischer Wirkung
US5063245A (en) 1990-03-28 1991-11-05 Nova Pharmaceutical Corporation Corticotropin-releasing factor antagonism compounds
CA2039411A1 (en) * 1990-03-30 1991-10-01 Ronnie Gerald Edie Thienopyrimidine derivatives
WO1994013676A1 (en) * 1992-12-17 1994-06-23 Pfizer Inc. Pyrrolopyrimidines as crf antagonists
TW370529B (en) * 1992-12-17 1999-09-21 Pfizer Pyrazolopyrimidines
TW574214B (en) 1994-06-08 2004-02-01 Pfizer Corticotropin releasing factor antagonists
CA2194756A1 (en) * 1995-05-12 1996-11-14 Jun Yuan Novel deazapurine derivatives; a new class of crf1 specific ligands

Also Published As

Publication number Publication date
MY119118A (en) 2005-03-31
DE69708059T2 (de) 2002-07-18
NO981356D0 (no) 1998-03-25
ES2167710T3 (es) 2002-05-16
AR005731A1 (es) 1999-07-14
DK0882051T3 (da) 2002-02-25
NZ330118A (en) 2000-03-27
ID15904A (id) 1997-08-14
EP0882051A1 (de) 1998-12-09
WO1997029110A1 (en) 1997-08-14
NO981356L (no) 1998-07-09
AU725674B2 (en) 2000-10-19
AU1720997A (en) 1997-08-28
CA2233307A1 (en) 1997-08-14
US6469166B2 (en) 2002-10-22
TW448178B (en) 2001-08-01
PT882051E (pt) 2002-04-29
DE69708059D1 (en) 2001-12-13
US6255310B1 (en) 2001-07-03
US20020052362A1 (en) 2002-05-02
EP0882051B1 (de) 2001-11-07
JP2000504678A (ja) 2000-04-18
KR19990067390A (ko) 1999-08-16

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Legal Events

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EEIH Change in the person of patent owner
REN Ceased due to non-payment of the annual fee