HK1132273A1 - - Google Patents
Info
- Publication number
- HK1132273A1 HK1132273A1 HK09112256.5A HK09112256A HK1132273A1 HK 1132273 A1 HK1132273 A1 HK 1132273A1 HK 09112256 A HK09112256 A HK 09112256A HK 1132273 A1 HK1132273 A1 HK 1132273A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- disorders
- pharmaceutically acceptable
- compounds
- stereoisomers
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/32—Oxygen atoms
- C07D209/36—Oxygen atoms in position 3, e.g. adrenochrome
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN45CH2007 | 2007-01-08 | ||
| PCT/IN2007/000312 WO2008084492A1 (en) | 2007-01-08 | 2007-07-26 | 5-(heterocyclyl)alkyl-n-(arylsulfonyl)indole compounds and their use as 5-ht6 ligands |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1132273A1 true HK1132273A1 (da) | 2010-02-19 |
Family
ID=39495814
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK09112256.5A HK1132273A1 (da) | 2007-01-08 | 2009-12-29 |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US8470830B2 (da) |
| EP (1) | EP2114878B1 (da) |
| JP (1) | JP2010515674A (da) |
| KR (1) | KR101103023B1 (da) |
| CN (1) | CN101553467B (da) |
| AT (1) | ATE491685T1 (da) |
| AU (1) | AU2007343063B2 (da) |
| BR (1) | BRPI0718737A2 (da) |
| CA (1) | CA2670717C (da) |
| CY (1) | CY1111105T1 (da) |
| DE (1) | DE602007011323D1 (da) |
| DK (1) | DK2114878T3 (da) |
| EA (1) | EA017007B1 (da) |
| ES (1) | ES2357584T3 (da) |
| HK (1) | HK1132273A1 (da) |
| IL (1) | IL198821A (da) |
| MX (1) | MX2009006077A (da) |
| NO (1) | NO341713B1 (da) |
| NZ (1) | NZ577769A (da) |
| PL (1) | PL2114878T3 (da) |
| PT (1) | PT2114878E (da) |
| WO (1) | WO2008084492A1 (da) |
| ZA (1) | ZA200903600B (da) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010032257A1 (en) * | 2008-09-17 | 2010-03-25 | Suven Life Sciences Limited | Aryl indolyl sulfonamide compounds and their use as 5-ht6 ligands |
| CN103304547A (zh) * | 2012-03-13 | 2013-09-18 | 中国药科大学 | 一种抗抑郁药维拉唑酮的制备方法 |
| EP3074378A4 (en) * | 2013-11-25 | 2017-05-10 | Novogen Ltd. | Functionalised and substituted indoles as anti-cancer agents |
| EP3083588B1 (en) | 2013-12-20 | 2020-12-09 | Sunshine Lake Pharma Co., Ltd. | Aromatic heterocyclic compounds and their application in pharmaceuticals |
| AU2015286049B2 (en) * | 2014-07-08 | 2018-03-01 | Sunshine Lake Pharma Co., Ltd. | Aromatic heterocyclic derivatives and pharmaceutical applications thereof |
| RU2017104856A (ru) * | 2014-07-16 | 2018-08-16 | Новоджен Лтд | Функционализированные и замещенные индолы в качестве противораковых средств |
| EP4175638A1 (en) * | 2020-07-06 | 2023-05-10 | Tactogen Inc. | Advantageous benzothiophene compositions for mental disorders or enhancement |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9026389D0 (en) * | 1990-12-05 | 1991-01-23 | Merck Sharp & Dohme | Therapeutic agents |
| US5700823A (en) * | 1994-01-07 | 1997-12-23 | Sugen, Inc. | Treatment of platelet derived growth factor related disorders such as cancers |
| DZ2376A1 (fr) | 1996-12-19 | 2002-12-28 | Smithkline Beecham Plc | Dérivés de sulfonamides nouveaux procédé pour leurpréparation et compositions pharmaceutiques les c ontenant. |
| TR200000073T2 (tr) | 1997-07-11 | 2000-06-21 | Smithkline Beecham P.L.C. | 5-HT6 Reseptör antagonistleri olan sülfonamid türevleri ve bunların hazırlanma prosesi |
| GB9801392D0 (en) | 1998-01-22 | 1998-03-18 | Smithkline Beecham Plc | Novel compounds |
| GB9803411D0 (en) | 1998-02-18 | 1998-04-15 | Smithkline Beecham Plc | Novel compounds |
| ATE375990T1 (de) | 1999-04-21 | 2007-11-15 | Nps Allelix Corp | Piperidin-indol derivate mit 5-ht6 affinität |
| GB9926302D0 (en) | 1999-11-05 | 2000-01-12 | Smithkline Beecham Plc | Novel compounds |
| AU2005102A (en) * | 2000-11-02 | 2002-05-15 | Wyeth Corp | 1-aryl- or 1-alkylsulfonyl-heterocyclylbenzazoles as 5-hydroxytryptamine-6 ligands |
| AU2002236730B2 (en) | 2001-01-30 | 2006-06-15 | Eli Lilly And Company | Benzenesulfonic acid indol-5-yl esters as antagonists of the 5-HT6 receptor |
| JP4443215B2 (ja) | 2001-02-08 | 2010-03-31 | メモリ ファーマセチカル コーポレーション | ホスホジエステラーゼ４阻害剤としてのトリフルオロメチルプリン |
| NZ529631A (en) | 2001-06-07 | 2006-08-31 | F | Indole derivatives with 5-hydroxytryptamine (5-HT) 5-HT6 receptor affinity in the treatment of disorders of the CNS |
| EP1414442A1 (en) * | 2001-08-07 | 2004-05-06 | Smithkline Beecham Plc | 3-arylsulfonyl-7-piperazinyl- indoles, -benzofurans and -benzothiophenes with 5-ht6 receptor affinity for treating cns disorders |
| US20050255529A1 (en) | 2002-02-01 | 2005-11-17 | Stefan Golz | Diagnostics and therapeutics for diseases associated with a new human 5-ht6 receptor |
| WO2003066056A1 (en) | 2002-02-05 | 2003-08-14 | Glaxo Group Limited | Method of promoting neuronal growth |
| KR101020399B1 (ko) | 2002-03-27 | 2011-03-08 | 글락소 그룹 리미티드 | 퀴놀린 유도체 및 5-ｈｔ6 리간드로서의 그의 용도 |
| WO2004048331A1 (en) | 2002-11-28 | 2004-06-10 | Suven Life Sciences Limited | N-arylalkyl-3-aminoalkoxyindoles and their use as 5-ht ligands |
| JP4559230B2 (ja) * | 2002-11-28 | 2010-10-06 | スベン ライフ サイエンシズ リミティド | セロトニン受容体に対する親和性を有する新規ｎ−アリールスルホニル−３−置換されたインドール、その調製方法、それを含有する医薬組成物 |
| PT1567492E (pt) | 2002-11-28 | 2013-07-22 | Suven Life Sciences Ltd | N-arilsulfonil-3-aminoalcoxi-indóis |
| BRPI0316895C1 (pt) | 2002-12-18 | 2021-05-25 | Suven Life Sciences Ltd | composto, processo para a preparação do composto, composição farmacêutica e uso do composto |
| WO2004108671A1 (en) * | 2003-06-06 | 2004-12-16 | Suven Life Sciences Limited | Substituted indoles with serotonin receptor affinity, process for their preparation and pharmaceutical compositions containing them |
| ES2222828B1 (es) | 2003-07-30 | 2006-04-16 | Laboratorios Del Dr. Esteve, S.A. | Derivados de 1-sulfonilindoles, su preparacion y su aplicacion como medicamentos. |
| NZ566495A (en) | 2005-08-12 | 2010-06-25 | Suven Life Sciences Ltd | Aminoaryl sulphonamide derivatives as functional 5-HT6 ligands |
| CN101484420B (zh) * | 2006-07-03 | 2014-04-30 | 比奥维特罗姆上市公司 | 作为5-ht6调节剂的吲哚 |
-
2007
- 2007-07-26 CA CA2670717A patent/CA2670717C/en not_active Expired - Fee Related
- 2007-07-26 BR BRPI0718737-8A2A patent/BRPI0718737A2/pt not_active Application Discontinuation
- 2007-07-26 EA EA200970675A patent/EA017007B1/ru not_active IP Right Cessation
- 2007-07-26 DK DK07827525.2T patent/DK2114878T3/da active
- 2007-07-26 NZ NZ577769A patent/NZ577769A/en not_active IP Right Cessation
- 2007-07-26 ES ES07827525T patent/ES2357584T3/es active Active
- 2007-07-26 JP JP2009544495A patent/JP2010515674A/ja active Pending
- 2007-07-26 AU AU2007343063A patent/AU2007343063B2/en not_active Ceased
- 2007-07-26 EP EP07827525A patent/EP2114878B1/en active Active
- 2007-07-26 US US12/521,967 patent/US8470830B2/en not_active Expired - Fee Related
- 2007-07-26 WO PCT/IN2007/000312 patent/WO2008084492A1/en active Application Filing
- 2007-07-26 KR KR1020097011686A patent/KR101103023B1/ko active IP Right Grant
- 2007-07-26 DE DE602007011323T patent/DE602007011323D1/de active Active
- 2007-07-26 AT AT07827525T patent/ATE491685T1/de active
- 2007-07-26 PT PT07827525T patent/PT2114878E/pt unknown
- 2007-07-26 PL PL07827525T patent/PL2114878T3/pl unknown
- 2007-07-26 CN CN2007800454515A patent/CN101553467B/zh not_active Expired - Fee Related
- 2007-07-26 MX MX2009006077A patent/MX2009006077A/es active IP Right Grant
-
2009
- 2009-05-19 IL IL198821A patent/IL198821A/en active IP Right Grant
- 2009-05-25 ZA ZA200903600A patent/ZA200903600B/xx unknown
- 2009-05-27 NO NO20092067A patent/NO341713B1/no not_active IP Right Cessation
- 2009-12-29 HK HK09112256.5A patent/HK1132273A1/xx not_active IP Right Cessation
-
2011
- 2011-01-13 CY CY20111100042T patent/CY1111105T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP2114878B1 (en) | 2010-12-15 |
| CA2670717C (en) | 2012-01-10 |
| MX2009006077A (es) | 2009-06-17 |
| US8470830B2 (en) | 2013-06-25 |
| BRPI0718737A2 (pt) | 2014-03-25 |
| CY1111105T1 (el) | 2015-06-11 |
| EA017007B1 (ru) | 2012-09-28 |
| CA2670717A1 (en) | 2008-07-17 |
| AU2007343063B2 (en) | 2011-02-17 |
| EA200970675A1 (ru) | 2009-12-30 |
| ATE491685T1 (de) | 2011-01-15 |
| CN101553467B (zh) | 2011-12-07 |
| NO20092067L (no) | 2009-09-04 |
| KR101103023B1 (ko) | 2012-01-05 |
| US20100041673A1 (en) | 2010-02-18 |
| IL198821A0 (en) | 2010-02-17 |
| NO341713B1 (no) | 2018-01-08 |
| WO2008084492A1 (en) | 2008-07-17 |
| ZA200903600B (en) | 2010-07-28 |
| AU2007343063A1 (en) | 2008-07-17 |
| NZ577769A (en) | 2011-01-28 |
| PT2114878E (pt) | 2011-03-10 |
| PL2114878T3 (pl) | 2011-05-31 |
| ES2357584T3 (es) | 2011-04-27 |
| EP2114878A1 (en) | 2009-11-11 |
| JP2010515674A (ja) | 2010-05-13 |
| CN101553467A (zh) | 2009-10-07 |
| IL198821A (en) | 2014-11-30 |
| KR20090080544A (ko) | 2009-07-24 |
| DK2114878T3 (da) | 2011-03-14 |
| DE602007011323D1 (de) | 2011-01-27 |
| AU2007343063A8 (en) | 2009-07-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20200728 |