HK1126474A1 - Novel pyridopyrazines and their use as modulators of kinases - Google Patents

Novel pyridopyrazines and their use as modulators of kinases

Info

Publication number
HK1126474A1
HK1126474A1 HK09104745.1A HK09104745A HK1126474A1 HK 1126474 A1 HK1126474 A1 HK 1126474A1 HK 09104745 A HK09104745 A HK 09104745A HK 1126474 A1 HK1126474 A1 HK 1126474A1
Authority
HK
Hong Kong
Prior art keywords
kinases
modulators
pyridopyrazines
novel
novel pyridopyrazines
Prior art date
Application number
HK09104745.1A
Other languages
English (en)
Inventor
E Claus
I Seipelt
E Guenther
E Polymeropoulos
M Czech
T Schuster
Original Assignee
Aeterna Zentaris Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from EP05024693A external-priority patent/EP1785423A1/de
Application filed by Aeterna Zentaris Gmbh filed Critical Aeterna Zentaris Gmbh
Publication of HK1126474A1 publication Critical patent/HK1126474A1/en

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    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
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    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
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HK09104745.1A 2005-11-11 2009-05-26 Novel pyridopyrazines and their use as modulators of kinases HK1126474A1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US73569805P 2005-11-11 2005-11-11
EP05024693A EP1785423A1 (de) 2005-11-11 2005-11-11 Neue Pyridopyrazine und deren Verwendung als Modulatoren von Kinasen
US84976106P 2006-10-06 2006-10-06
PCT/EP2006/068322 WO2007054556A1 (de) 2005-11-11 2006-11-10 Neue pyridopyrazine und deren verwendung als modulatoren von kinasen

Publications (1)

Publication Number Publication Date
HK1126474A1 true HK1126474A1 (en) 2009-09-04

Family

ID=37654792

Family Applications (1)

Application Number Title Priority Date Filing Date
HK09104745.1A HK1126474A1 (en) 2005-11-11 2009-05-26 Novel pyridopyrazines and their use as modulators of kinases

Country Status (10)

Country Link
EP (1) EP1957487A1 (de)
JP (1) JP5527972B2 (de)
KR (1) KR101400905B1 (de)
AR (1) AR060010A1 (de)
AU (1) AU2006313701B2 (de)
CA (1) CA2628039A1 (de)
HK (1) HK1126474A1 (de)
IL (1) IL191139A0 (de)
NO (1) NO20082511L (de)
WO (1) WO2007054556A1 (de)

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EP1790342A1 (de) 2005-11-11 2007-05-30 Zentaris GmbH Pyridopyrazin-Derivate und deren Verwendung als Modulatoren der Signaltransduktionswege
EP1990342A1 (de) * 2007-05-10 2008-11-12 AEterna Zentaris GmbH Pyridopyrazin-Derivate sowie Herstellungs- und Verwendungsverfahren dafür
EP2170338A2 (de) * 2007-07-06 2010-04-07 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Dna-pkcs zur modulierung von energieregulation und gehirnfunktion
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EP2508184A1 (de) 2011-04-06 2012-10-10 Æterna Zentaris GmbH Pyridopyrazinderivate und ihre Verwendungen
GB201118652D0 (en) 2011-10-28 2011-12-07 Astex Therapeutics Ltd New compounds
GB201118675D0 (en) 2011-10-28 2011-12-14 Astex Therapeutics Ltd New compounds
GB201118654D0 (en) 2011-10-28 2011-12-07 Astex Therapeutics Ltd New compounds
GB201118656D0 (en) 2011-10-28 2011-12-07 Astex Therapeutics Ltd New compounds
GB201209613D0 (en) 2012-05-30 2012-07-11 Astex Therapeutics Ltd New compounds
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GB201307577D0 (en) 2013-04-26 2013-06-12 Astex Therapeutics Ltd New compounds
WO2015144808A1 (en) 2014-03-26 2015-10-01 Astex Therapeutics Ltd Combinations of an fgfr inhibitor and an igf1r inhibitor
SI3122358T1 (sl) 2014-03-26 2021-04-30 Astex Therapeutics Ltd. Kombinacije FGFR- in CMET-inhibitorjev za zdravljenje raka
JO3512B1 (ar) 2014-03-26 2020-07-05 Astex Therapeutics Ltd مشتقات كينوكسالين مفيدة كمعدلات لإنزيم fgfr كيناز
JOP20200201A1 (ar) 2015-02-10 2017-06-16 Astex Therapeutics Ltd تركيبات صيدلانية تشتمل على n-(3.5- ثنائي ميثوكسي فينيل)-n'-(1-ميثيل إيثيل)-n-[3-(ميثيل-1h-بيرازول-4-يل) كينوكسالين-6-يل]إيثان-1.2-ثنائي الأمين
US10478494B2 (en) 2015-04-03 2019-11-19 Astex Therapeutics Ltd FGFR/PD-1 combination therapy for the treatment of cancer
ES2904513T3 (es) 2015-09-23 2022-04-05 Janssen Pharmaceutica Nv 1,4-Benzodiazepinas biheteroarilo sustituidas y usos de las mismas para el tratamiento del cáncer
BR112018005637B1 (pt) 2015-09-23 2023-11-28 Janssen Pharmaceutica Nv Compostos derivados de quinoxalina, quinolina e quinazolinona,composições farmacêuticas que os compreende, e uso dos referidos compostos

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JP5527972B2 (ja) 2014-06-25
AU2006313701A1 (en) 2007-05-18
EP1957487A1 (de) 2008-08-20
IL191139A0 (en) 2008-12-29
KR20080068117A (ko) 2008-07-22
CA2628039A1 (en) 2007-05-18
AU2006313701B2 (en) 2012-05-31
AR060010A1 (es) 2008-05-21
WO2007054556A1 (de) 2007-05-18
JP2009515853A (ja) 2009-04-16
KR101400905B1 (ko) 2014-05-29
NO20082511L (no) 2008-06-24

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