HK1074588A1 - Aqueous suspension comprising fenofibrate - Google Patents
Aqueous suspension comprising fenofibrateInfo
- Publication number
- HK1074588A1 HK1074588A1 HK05108777A HK05108777A HK1074588A1 HK 1074588 A1 HK1074588 A1 HK 1074588A1 HK 05108777 A HK05108777 A HK 05108777A HK 05108777 A HK05108777 A HK 05108777A HK 1074588 A1 HK1074588 A1 HK 1074588A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- surfactant
- fenofibrate
- aqueous suspension
- cellulose derivative
- micronized fenofibrate
- Prior art date
Links
- YMTINGFKWWXKFG-UHFFFAOYSA-N fenofibrate Chemical compound C1=CC(OC(C)(C)C(=O)OC(C)C)=CC=C1C(=O)C1=CC=C(Cl)C=C1 YMTINGFKWWXKFG-UHFFFAOYSA-N 0.000 title abstract 4
- 229960002297 fenofibrate Drugs 0.000 title abstract 4
- 239000007900 aqueous suspension Substances 0.000 title abstract 2
- 229920002678 cellulose Polymers 0.000 abstract 3
- 239000001913 cellulose Substances 0.000 abstract 3
- 239000000203 mixture Substances 0.000 abstract 3
- 239000004094 surface-active agent Substances 0.000 abstract 3
- 238000004519 manufacturing process Methods 0.000 abstract 2
- 239000011230 binding agent Substances 0.000 abstract 1
- 238000001035 drying Methods 0.000 abstract 1
- 239000008187 granular material Substances 0.000 abstract 1
- 230000007935 neutral effect Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 238000012216 screening Methods 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- 238000005507 spraying Methods 0.000 abstract 1
- 238000009736 wetting Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
- A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
- A61K9/1676—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface having a drug-free core with discrete complete coating layer containing drug
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Biophysics (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Diabetes (AREA)
- Emergency Medicine (AREA)
- Obesity (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9908923A FR2795961B1 (fr) | 1999-07-09 | 1999-07-09 | Composition pharmaceutique contenant du fenofibrate micronise, un tensioactif et un derive cellulosique liant et procede de preparation |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1074588A1 true HK1074588A1 (en) | 2005-11-18 |
Family
ID=9547923
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK02106433.0A HK1044894B (zh) | 1999-07-09 | 2002-08-30 | 包含非諾貝特的藥物成分和製備方法 |
HK05108777A HK1074588A1 (en) | 1999-07-09 | 2005-10-04 | Aqueous suspension comprising fenofibrate |
HK06103039A HK1080391A1 (en) | 1999-07-09 | 2006-03-09 | Pharmaceutical composition comprising fenofibrate and process for its preparation |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK02106433.0A HK1044894B (zh) | 1999-07-09 | 2002-08-30 | 包含非諾貝特的藥物成分和製備方法 |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK06103039A HK1080391A1 (en) | 1999-07-09 | 2006-03-09 | Pharmaceutical composition comprising fenofibrate and process for its preparation |
Country Status (37)
Country | Link |
---|---|
US (4) | US7101574B1 (xx) |
EP (3) | EP1194140B1 (xx) |
JP (2) | JP4841092B2 (xx) |
KR (3) | KR20020025188A (xx) |
CN (2) | CN1682707B (xx) |
AT (3) | ATE291912T1 (xx) |
AU (1) | AU782282B2 (xx) |
BG (1) | BG65504B1 (xx) |
BR (1) | BR0012335A (xx) |
CA (1) | CA2377909C (xx) |
CY (1) | CY1106206T1 (xx) |
CZ (1) | CZ300094B6 (xx) |
DE (3) | DE60031184T2 (xx) |
DK (3) | DK1194140T3 (xx) |
EA (1) | EA004294B1 (xx) |
EE (1) | EE04995B1 (xx) |
ES (3) | ES2271924T3 (xx) |
FR (1) | FR2795961B1 (xx) |
GE (1) | GEP20043287B (xx) |
HK (3) | HK1044894B (xx) |
HR (1) | HRP20020111B1 (xx) |
HU (1) | HU229044B1 (xx) |
IL (2) | IL147499A0 (xx) |
IS (1) | IS2157B (xx) |
ME (1) | ME01361B (xx) |
MX (1) | MXPA02000324A (xx) |
NO (1) | NO333301B1 (xx) |
NZ (1) | NZ516416A (xx) |
PL (1) | PL212082B1 (xx) |
PT (3) | PT1194140E (xx) |
RS (1) | RS50035B (xx) |
SI (2) | SI1574214T1 (xx) |
SK (1) | SK287484B6 (xx) |
TR (1) | TR200200008T2 (xx) |
UA (1) | UA72925C2 (xx) |
WO (1) | WO2001003693A1 (xx) |
ZA (1) | ZA200200169B (xx) |
Families Citing this family (42)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2795961B1 (fr) | 1999-07-09 | 2004-05-28 | Ethypharm Lab Prod Ethiques | Composition pharmaceutique contenant du fenofibrate micronise, un tensioactif et un derive cellulosique liant et procede de preparation |
US7863331B2 (en) | 1999-07-09 | 2011-01-04 | Ethypharm | Pharmaceutical composition containing fenofibrate and method for the preparation thereof |
US20080241070A1 (en) * | 2000-09-21 | 2008-10-02 | Elan Pharma International Ltd. | Fenofibrate dosage forms |
FR2819720B1 (fr) * | 2001-01-22 | 2004-03-12 | Fournier Lab Sa | Nouveaux comprimes de fenofibrate |
GB0119480D0 (en) | 2001-08-09 | 2001-10-03 | Jagotec Ag | Novel compositions |
DK1551372T3 (en) * | 2002-09-20 | 2018-07-23 | Alpharma Pharmaceuticals Llc | SEQUERATION SUBSTANCES AND RELATED COMPOSITIONS AND PROCEDURES |
WO2004028506A1 (en) * | 2002-09-24 | 2004-04-08 | Ranbaxy Laboratories Limited | Oral pharmaceutical compositions of fenofibrate having high bioavailability |
CN100367947C (zh) * | 2002-12-04 | 2008-02-13 | 徐州恩华赛德药业有限责任公司 | 具有抗高血脂症的含非诺贝特的药物组合物 |
EP1572190B1 (en) * | 2002-12-17 | 2007-04-18 | Abbott GmbH & Co. KG | Formulation comprising fenofibric acid, a physiologically acceptable salt or derivative thereof |
US20080051411A1 (en) * | 2002-12-17 | 2008-02-28 | Cink Russell D | Salts of Fenofibric Acid and Pharmaceutical Formulations Thereof |
EP1832285A1 (en) * | 2002-12-17 | 2007-09-12 | Abbott GmbH & Co. KG | Formulation comprising fenofibric acid or a physiologically acceptable salt thereof |
MXPA06000111A (es) * | 2003-07-02 | 2006-04-27 | Abbott Lab | Proceso para preparar formulaciones de farmacos que regulan lipidos. |
US7264813B2 (en) | 2003-09-24 | 2007-09-04 | Nikken Sohonsha Corporation | Therapeutic uses of Dunaliella powder |
US8062664B2 (en) | 2003-11-12 | 2011-11-22 | Abbott Laboratories | Process for preparing formulations of lipid-regulating drugs |
US8026281B2 (en) * | 2004-10-14 | 2011-09-27 | Lupin Atlantis Holdings, S.A. | Treating metabolic syndrome with fenofibrate |
UA90708C2 (ru) * | 2005-02-25 | 2010-05-25 | Ф. Хоффманн-Ля Рош Аг | Таблетки с улучшенной дисперсностью лекарственного вещества |
CN101212962A (zh) * | 2005-03-30 | 2008-07-02 | 特瓦制药工业有限公司 | 包含薄荷醇或peg/泊洛沙姆的非诺贝特的改进制剂 |
US20080152714A1 (en) * | 2005-04-08 | 2008-06-26 | Yi Gao | Pharmaceutical Formulations |
AU2007252308A1 (en) * | 2006-05-23 | 2007-11-29 | Intelemetrix Ltd | Data accessing system and method |
EP2526932B1 (en) | 2006-06-19 | 2017-06-07 | Alpharma Pharmaceuticals LLC | Pharmaceutical composition |
KR100767349B1 (ko) * | 2006-08-01 | 2007-10-17 | 삼천당제약주식회사 | 페노피브레이트를 함유하는 경구용 약제 조성물 및 그의제조방법 |
EP1923053A1 (en) * | 2006-09-27 | 2008-05-21 | Novartis AG | Pharmaceutical compositions comprising nilotinib or its salt |
AU2007322269A1 (en) * | 2006-10-11 | 2008-05-29 | Alpharma Pharmaceuticals, Llc | Pharmaceutical compositions |
JP4993274B2 (ja) * | 2006-12-05 | 2012-08-08 | 日医工株式会社 | フェノフィブラート含有製剤組成物の製造方法 |
US20090196890A1 (en) * | 2007-12-17 | 2009-08-06 | Alpharma Pharmaceuticals, Llc | Pharmaceutical compositions |
US8623418B2 (en) | 2007-12-17 | 2014-01-07 | Alpharma Pharmaceuticals Llc | Pharmaceutical composition |
FR2940118B1 (fr) * | 2008-12-24 | 2013-08-09 | Ethypharm Sa | Formulation pharmaceutique de fenofibrate nanonise |
JPWO2010092925A1 (ja) * | 2009-02-12 | 2012-08-16 | あすか製薬株式会社 | 固体分散体とその医薬組成物、並びにそれらの製造方法 |
CN101502497B (zh) * | 2009-03-06 | 2010-11-10 | 安徽省药物研究所 | 非诺贝特药物组合物 |
US20100291201A1 (en) * | 2009-05-14 | 2010-11-18 | Cerovene, Inc. | Coated pharmaceutical capsule dosage form |
KR101202994B1 (ko) * | 2010-04-12 | 2012-11-21 | 한미사이언스 주식회사 | 페노피브린산 및 알칼리화제를 포함하는 경구용 약학 조성물 |
US20140255480A1 (en) * | 2011-09-07 | 2014-09-11 | Ethypharm | Pharmaceutical formulation of nanonized fenofibrate |
KR101334585B1 (ko) * | 2012-05-29 | 2013-12-05 | 주식회사 브이터치 | 프로젝터를 통해 표시되는 정보를 이용하여 가상터치를 수행하는 원격 조작 장치 및 방법 |
US8722083B2 (en) | 2012-06-25 | 2014-05-13 | Mylan, Inc. | Fenofibrate formulation |
WO2014091318A1 (en) | 2012-12-11 | 2014-06-19 | Lupin Atlantis Holdings, S.A. | Reduced dose pharmaceutical compositions of fenofibrate |
EP3077098B1 (en) * | 2013-12-04 | 2018-03-07 | Dow Global Technologies LLC | Process for preparing a mixture of a cellulose derivative and a liquid diluent |
CN104352466A (zh) * | 2014-11-17 | 2015-02-18 | 辰欣药业股份有限公司 | 一种非诺贝特组合物及其制剂 |
CN107961224B (zh) * | 2017-12-06 | 2021-05-04 | 齐鲁制药(海南)有限公司 | 一种阿昔替尼片及其制备方法 |
KR102407512B1 (ko) | 2019-10-30 | 2022-06-13 | 주식회사 대웅테라퓨틱스 | 피브레이트계 화합물을 포함하는 근육 질환 예방 및 치료용 조성물 |
CN112121022A (zh) * | 2020-09-25 | 2020-12-25 | 迪沙药业集团有限公司 | 一种非诺贝特片组合物及其制备方法 |
WO2022071768A1 (en) * | 2020-09-29 | 2022-04-07 | Addpharma Inc. | A pharmaceutical composition comprising fenofibrate particles with improved bioavailability |
CN112121023A (zh) * | 2020-09-30 | 2020-12-25 | 迪沙药业集团有限公司 | 一种非诺贝特片组合物 |
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CH543472A (fr) | 1969-01-31 | 1973-10-31 | Orchimed Sa | Procédé pour la préparation d'acides phénoxyalcoyl-carboxyliques |
US4058552A (en) | 1969-01-31 | 1977-11-15 | Orchimed Sa | Esters of p-carbonylphenoxy-isobutyric acids |
GB1579818A (en) | 1977-06-07 | 1980-11-26 | Yamanouchi Pharma Co Ltd | Nifedipine-containing solid preparation composition |
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FR2494112B1 (xx) | 1980-11-19 | 1986-01-10 | Laruelle Claude | |
GB8414220D0 (en) | 1984-06-04 | 1984-07-11 | Sterwin Ag | Medicaments in unit dose form |
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FR2602423B1 (fr) * | 1986-08-08 | 1989-05-05 | Ethypharm Sa | Procede de preparation d'un medicament a base de fenofibrate, medicament obtenu par ce procede |
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FR2722984B1 (fr) | 1994-07-26 | 1996-10-18 | Effik Lab | Procede de preparation de formes pharmaceutiques seches et les compositions pharmaceutiques ainsi realisees |
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FR2758461A1 (fr) | 1997-01-17 | 1998-07-24 | Pharma Pass | Composition pharmaceutique presentant une biodisponibilite elevee et son procede de preparation |
FR2758459B1 (fr) * | 1997-01-17 | 1999-05-07 | Pharma Pass | Composition pharmaceutique de fenofibrate presentant une biodisponibilite elevee et son procede de preparation |
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US6368620B2 (en) * | 1999-06-11 | 2002-04-09 | Abbott Laboratories | Formulations comprising lipid-regulating agents |
US7863331B2 (en) * | 1999-07-09 | 2011-01-04 | Ethypharm | Pharmaceutical composition containing fenofibrate and method for the preparation thereof |
FR2795961B1 (fr) | 1999-07-09 | 2004-05-28 | Ethypharm Lab Prod Ethiques | Composition pharmaceutique contenant du fenofibrate micronise, un tensioactif et un derive cellulosique liant et procede de preparation |
US6667064B2 (en) | 2000-08-30 | 2003-12-23 | Pilot Therapeutics, Inc. | Composition and method for treatment of hypertriglyceridemia |
AU2001262945B2 (en) * | 2000-09-20 | 2006-02-02 | Skyepharma Canada Inc. | Spray drying process and compositions of fenofibrate |
US8026281B2 (en) * | 2004-10-14 | 2011-09-27 | Lupin Atlantis Holdings, S.A. | Treating metabolic syndrome with fenofibrate |
-
1999
- 1999-07-09 FR FR9908923A patent/FR2795961B1/fr not_active Expired - Lifetime
-
2000
- 2000-07-07 ES ES05006751T patent/ES2271924T3/es not_active Expired - Lifetime
- 2000-07-07 AT AT00949677T patent/ATE291912T1/de active
- 2000-07-07 EP EP00949677A patent/EP1194140B1/fr not_active Expired - Lifetime
- 2000-07-07 ES ES00949677T patent/ES2235919T3/es not_active Expired - Lifetime
- 2000-07-07 AU AU62960/00A patent/AU782282B2/en not_active Expired
- 2000-07-07 DE DE60031184T patent/DE60031184T2/de not_active Expired - Lifetime
- 2000-07-07 DE DE60019120T patent/DE60019120T2/de not_active Expired - Lifetime
- 2000-07-07 IL IL14749900A patent/IL147499A0/xx active IP Right Grant
- 2000-07-07 WO PCT/FR2000/001971 patent/WO2001003693A1/fr not_active Application Discontinuation
- 2000-07-07 SI SI200030894T patent/SI1574214T1/sl unknown
- 2000-07-07 DE DE60039313T patent/DE60039313D1/de not_active Expired - Lifetime
- 2000-07-07 ES ES04027226T patent/ES2309438T3/es not_active Expired - Lifetime
- 2000-07-07 AT AT05006751T patent/ATE341320T1/de active
- 2000-07-07 JP JP2001508973A patent/JP4841092B2/ja not_active Expired - Lifetime
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2002
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2005
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2006
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- 2006-05-29 KR KR1020060048212A patent/KR20060073549A/ko not_active Application Discontinuation
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2007
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2008
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2010
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2011
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PE | Patent expired |
Effective date: 20200706 |