HK1043313A1 - 用於治療癌症的多西他賽和rhumab her2 - Google Patents
用於治療癌症的多西他賽和rhumab her2Info
- Publication number
- HK1043313A1 HK1043313A1 HK02104971.3A HK02104971A HK1043313A1 HK 1043313 A1 HK1043313 A1 HK 1043313A1 HK 02104971 A HK02104971 A HK 02104971A HK 1043313 A1 HK1043313 A1 HK 1043313A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- docetaxel
- rhumab her2
- cancers
- treatment
- combination
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Oncology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Drying Of Gases (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US12856499P | 1999-04-09 | 1999-04-09 | |
PCT/US2000/009247 WO2000061185A1 (en) | 1999-04-09 | 2000-04-07 | Docetaxel in combination with rhumab her2 for the treatment of cancers |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1043313A1 true HK1043313A1 (zh) | 2002-09-13 |
Family
ID=22435924
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK02104971.3A HK1043313A1 (zh) | 1999-04-09 | 2002-07-02 | 用於治療癌症的多西他賽和rhumab her2 |
HK02107549.9A HK1046093B (zh) | 1999-04-09 | 2002-10-17 | 用於治療癌症的泰素帝和重組人源化her2單克隆抗體的組合 |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK02107549.9A HK1046093B (zh) | 1999-04-09 | 2002-10-17 | 用於治療癌症的泰素帝和重組人源化her2單克隆抗體的組合 |
Country Status (22)
Country | Link |
---|---|
US (1) | US6333348B1 (zh) |
EP (1) | EP1169059B1 (zh) |
JP (2) | JP2003512298A (zh) |
KR (1) | KR100695383B1 (zh) |
CN (1) | CN1191859C (zh) |
AT (1) | ATE307608T1 (zh) |
AU (1) | AU777661B2 (zh) |
BR (1) | BR0009647A (zh) |
CA (1) | CA2368369C (zh) |
CZ (1) | CZ296373B6 (zh) |
DE (1) | DE60023476T2 (zh) |
DK (1) | DK1169059T3 (zh) |
EA (1) | EA006097B1 (zh) |
ES (1) | ES2248070T3 (zh) |
HK (2) | HK1043313A1 (zh) |
HU (1) | HU226672B1 (zh) |
MX (1) | MXPA01010138A (zh) |
NO (1) | NO332619B1 (zh) |
NZ (1) | NZ515337A (zh) |
TR (1) | TR200102845T2 (zh) |
WO (1) | WO2000061185A1 (zh) |
ZA (1) | ZA200107771B (zh) |
Families Citing this family (65)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ZA9811162B (en) | 1997-12-12 | 2000-06-07 | Genentech Inc | Treatment with anti-ERBB2 antibodies. |
ES2533255T3 (es) * | 1998-07-13 | 2015-04-08 | Board Of Regents, The University Of Texas System | Utilización de anticuerpos anti-aminofosfolípidos para el tratamiento del cáncer |
US6818213B1 (en) * | 1998-07-13 | 2004-11-16 | Board Of Regents, The University Of Texas System | Cancer treatment compositions comprising therapeutic conjugates that bind to aminophospholipids |
US6406693B1 (en) * | 1998-07-13 | 2002-06-18 | Board Of Regents, The University Of Texas System | Cancer treatment methods using antibodies to aminophospholipids |
WO2000002587A1 (en) * | 1998-07-13 | 2000-01-20 | Board Of Regents, The University Of Texas System | Cancer treatment methods using therapeutic conjugates that bind to aminophospholipids |
US6333348B1 (en) * | 1999-04-09 | 2001-12-25 | Aventis Pharma S.A. | Use of docetaxel for treating cancers |
US6949245B1 (en) | 1999-06-25 | 2005-09-27 | Genentech, Inc. | Humanized anti-ErbB2 antibodies and treatment with anti-ErbB2 antibodies |
US7041292B1 (en) | 1999-06-25 | 2006-05-09 | Genentech, Inc. | Treating prostate cancer with anti-ErbB2 antibodies |
JP4579471B2 (ja) * | 1999-06-25 | 2010-11-10 | ジェネンテック, インコーポレイテッド | 抗ErbB2抗体を用いる前立腺癌の処置 |
US20040013667A1 (en) * | 1999-06-25 | 2004-01-22 | Genentech, Inc. | Treatment with anti-ErbB2 antibodies |
GB9917012D0 (en) * | 1999-07-20 | 1999-09-22 | Pharmacia & Upjohn Spa | Combined preparations comprising antitumor agents |
KR20090024308A (ko) * | 1999-08-27 | 2009-03-06 | 제넨테크, 인크. | 항-ErbB2 항체 투여 치료 방법 |
JP2003534292A (ja) | 2000-05-19 | 2003-11-18 | ジェネンテック・インコーポレーテッド | Erbbアンタゴニスト癌治療に対する有効な応答の可能性を向上させるための遺伝子検出アッセイ |
WO2002041914A1 (en) * | 2000-11-21 | 2002-05-30 | Cell Pathways, Inc. | Method for treating neoplasia by administering an anti-her2 antibody and a cgmp-specific phosphodiesterase inhibitor |
EP1353693B1 (en) * | 2001-01-16 | 2005-03-16 | Glaxo Group Limited | Pharmaceutical combination containing a 4-quinazolineamine and paclitaxel, carboplatin or vinorelbine for the treatment of cancer |
PT2762140T (pt) | 2001-02-19 | 2017-07-04 | Novartis Ag | Resumo |
WO2002087629A1 (en) * | 2001-04-26 | 2002-11-07 | Analogic Corporation | Ct scanner for imaging a preselected portion of a patient |
US7452539B2 (en) * | 2001-12-19 | 2008-11-18 | Genentech, Inc. | Stabilizing polypeptides which have been exposed to urea |
GB0200657D0 (en) * | 2002-01-12 | 2002-02-27 | Antisoma Plc | Cancer treatment |
US7247303B2 (en) * | 2002-07-15 | 2007-07-24 | Board Of Regents, The University Of Texas System | Selected antibody CDRs for binding to aminophospholipids |
US7622118B2 (en) * | 2002-07-15 | 2009-11-24 | Board Of Regents, The University Of Texas System | Cancer treatment methods using selected antibodies to aminophospholipids |
US7678386B2 (en) | 2002-07-15 | 2010-03-16 | Board Of Regents The University Of Texas | Liposomes coated with selected antibodies that bind to aminophospholipids |
US7625563B2 (en) * | 2002-07-15 | 2009-12-01 | Board Of Regents, The University Of Texas System | Cancer treatment methods using selected immunoconjugates for binding to aminophospholipids |
US7572448B2 (en) * | 2002-07-15 | 2009-08-11 | Board Of Regents, The University Of Texas System | Combined cancer treatment methods using selected antibodies to aminophospholipids |
CN104225610B (zh) * | 2002-07-15 | 2017-03-01 | 得克萨斯大学体系董事会 | 与阴离子磷脂和氨基磷脂结合的选定抗体及其治疗用途 |
US7615223B2 (en) * | 2002-07-15 | 2009-11-10 | Board Of Regents, The University Of Texas System | Selected immunoconjugates for binding to aminophospholipids |
US7714109B2 (en) * | 2002-07-15 | 2010-05-11 | Board Of Regents, The University Of Texas System | Combinations and kits for cancer treatment using selected antibodies to aminophospholipids |
JP2006516117A (ja) * | 2002-11-21 | 2006-06-22 | ジェネンテック・インコーポレーテッド | 抗ErbB2抗体を用いた非悪性疾病または疾患の治療 |
US7989490B2 (en) | 2004-06-02 | 2011-08-02 | Cordis Corporation | Injectable formulations of taxanes for cad treatment |
KR20130089280A (ko) | 2005-01-21 | 2013-08-09 | 제넨테크, 인크. | Her 항체의 고정 용량 투여법 |
CA2595395A1 (en) * | 2005-02-09 | 2006-08-17 | Genentech, Inc. | Inhibiting her2 shedding with matrix metalloprotease antagonists |
MY152164A (en) | 2005-02-23 | 2014-08-15 | Genentech Inc | Extending time to disease progression or survival in cancer patients |
JP2006316040A (ja) | 2005-05-13 | 2006-11-24 | Genentech Inc | Herceptin(登録商標)補助療法 |
WO2007038792A2 (en) * | 2005-09-28 | 2007-04-05 | H. Lee Moffitt Cancer Center | Individualized cancer treatments |
EP1913958B1 (en) * | 2006-08-03 | 2009-12-23 | Sanofi-Aventis | Antitumor compositions containing acetylcyclopropyl docetaxel and trastuzumab |
FR2904782B1 (fr) * | 2006-08-11 | 2008-10-31 | Delta Proteomics Soc Par Actio | Co-colloides supramoleculaires obtenus a l'aide de systemes macrocycliques polyanioniques |
BRPI0808418A2 (pt) | 2007-03-02 | 2014-07-22 | Genentech Inc | Predição de resposta a um inibidor de her |
DK2171090T3 (da) | 2007-06-08 | 2013-06-10 | Genentech Inc | Genekspressionsmarkører for tumorresistens over for HER2-inhibitorbehandling |
US9551033B2 (en) | 2007-06-08 | 2017-01-24 | Genentech, Inc. | Gene expression markers of tumor resistance to HER2 inhibitor treatment |
EP2133433A1 (en) * | 2008-06-09 | 2009-12-16 | Centre Georges François Leclerc | A method for predicting responsiveness to a treatment with an anti-HER2 antibody |
BRPI0812682A2 (pt) | 2008-06-16 | 2010-06-22 | Genentech Inc | tratamento de cáncer de mama metastático |
WO2010061269A2 (en) * | 2008-11-02 | 2010-06-03 | Optimata Ltd. | Improving cancer therapy by docetaxel and granulocyte colony-stimulating factor (g-csf) |
MD24Z (ro) * | 2008-12-02 | 2010-01-31 | Василе ЖОВМИР | Metodă de tratament diferenţiat al carcinomului neinvaziv al glandei mamare |
MD35Z (ro) * | 2008-12-02 | 2010-01-31 | Василе ЖОВМИР | Metodă de apreciere a riscului dezvoltării carcinomului neinvaziv in situ al glandei mamare |
MD36Z (ro) * | 2008-12-02 | 2010-01-31 | Василе ЖОВМИР | Metodă de tratament diferenţiat al carcinomului ductal in situ neinvaziv al glandei mamare |
MD23Z (ro) * | 2008-12-02 | 2010-01-31 | Василе ЖОВМИР | Metodă de tratament diferenţiat al carcinomului lobular in situ neinvaziv al glandei mamare |
CN102356092B (zh) | 2009-03-20 | 2014-11-05 | 霍夫曼-拉罗奇有限公司 | 双特异性抗-her抗体 |
EP2435071A1 (en) | 2009-05-29 | 2012-04-04 | F. Hoffmann-La Roche AG | Modulators for her2 signaling in her2 expressing patients with gastric cancer |
RU2587619C2 (ru) | 2010-02-18 | 2016-06-20 | Дженентек, Инк. | Антагонисты неурегулина и применение их в лечении злокачественного новообразования |
WO2011139172A1 (en) | 2010-05-06 | 2011-11-10 | Goran Milosavljevic | Diterpene compounds with antineoplastic activities and pharmaceutical compositions comprising same |
WO2011146568A1 (en) | 2010-05-19 | 2011-11-24 | Genentech, Inc. | Predicting response to a her inhibitor |
WO2012069466A1 (en) | 2010-11-24 | 2012-05-31 | Novartis Ag | Multispecific molecules |
SG191153A1 (en) | 2010-12-23 | 2013-07-31 | Hoffmann La Roche | Polypeptide-polynucleotide-complex and its use in targeted effector moiety delivery |
EP2744824A1 (en) | 2011-08-17 | 2014-06-25 | F.Hoffmann-La Roche Ag | Neuregulin antibodies and uses thereof |
MX357759B (es) * | 2011-09-01 | 2018-07-24 | Vascular Biogenics Ltd | Formulaciones y formas de dosificacion de fosfolipidos oxidados. |
CN102321175B (zh) * | 2011-09-21 | 2013-08-07 | 天津胜发生物技术有限公司 | 针对乳腺癌Her2/new的纳米抗体或多肽 |
WO2013063229A1 (en) | 2011-10-25 | 2013-05-02 | The Regents Of The University Of Michigan | Her2 targeting agent treatment in non-her2-amplified cancers having her2 expressing cancer stem cells |
SG11201402510TA (en) | 2011-11-30 | 2014-06-27 | Genentech Inc | Erbb3 mutations in cancer |
US9376715B2 (en) | 2011-12-09 | 2016-06-28 | Roche Molecular Systems, Inc | Methods for detecting mutations in the catalytic subunit of the phosphoinositol-3 kinase (PIK3CA) gene |
EP2831115A1 (en) | 2012-03-27 | 2015-02-04 | F. Hoffmann-La Roche AG | Diagnosis and treatments relating to her3 inhibitors |
US9308235B2 (en) * | 2012-05-09 | 2016-04-12 | Spectrum Pharmaceuticals, Inc. | Treatment of primary and metastatic carcinoma |
JP6998646B2 (ja) | 2012-11-30 | 2022-02-04 | エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト | Pd-l1阻害剤併用療法を必要とする患者の同定 |
CN103102414B (zh) * | 2013-02-04 | 2014-08-27 | 无锡傲锐东源生物科技有限公司 | 抗her2蛋白单克隆抗体及其用途 |
WO2017194554A1 (en) | 2016-05-10 | 2017-11-16 | Inserm (Institut National De La Sante Et De La Recherche Medicale) | Combinations therapies for the treatment of cancer |
CN109966499A (zh) * | 2019-04-25 | 2019-07-05 | 苏州大学 | 协同增效的抗乳腺癌转移药物组合物及其用途 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6214388B1 (en) | 1994-11-09 | 2001-04-10 | The Regents Of The University Of California | Immunoliposomes that optimize internalization into target cells |
ZA9811162B (en) | 1997-12-12 | 2000-06-07 | Genentech Inc | Treatment with anti-ERBB2 antibodies. |
US6333348B1 (en) * | 1999-04-09 | 2001-12-25 | Aventis Pharma S.A. | Use of docetaxel for treating cancers |
-
2000
- 2000-04-06 US US09/544,176 patent/US6333348B1/en not_active Expired - Lifetime
- 2000-04-07 BR BR0009647-4A patent/BR0009647A/pt not_active Application Discontinuation
- 2000-04-07 MX MXPA01010138A patent/MXPA01010138A/es active IP Right Grant
- 2000-04-07 EA EA200101064A patent/EA006097B1/ru not_active IP Right Cessation
- 2000-04-07 DK DK00923156T patent/DK1169059T3/da active
- 2000-04-07 ES ES00923156T patent/ES2248070T3/es not_active Expired - Lifetime
- 2000-04-07 AU AU43327/00A patent/AU777661B2/en not_active Ceased
- 2000-04-07 NZ NZ515337A patent/NZ515337A/en not_active IP Right Cessation
- 2000-04-07 CZ CZ20013614A patent/CZ296373B6/cs not_active IP Right Cessation
- 2000-04-07 CN CNB008060886A patent/CN1191859C/zh not_active Expired - Fee Related
- 2000-04-07 CA CA2368369A patent/CA2368369C/en not_active Expired - Fee Related
- 2000-04-07 JP JP2000610517A patent/JP2003512298A/ja active Pending
- 2000-04-07 TR TR2001/02845T patent/TR200102845T2/xx unknown
- 2000-04-07 AT AT00923156T patent/ATE307608T1/de active
- 2000-04-07 KR KR1020017012798A patent/KR100695383B1/ko not_active IP Right Cessation
- 2000-04-07 WO PCT/US2000/009247 patent/WO2000061185A1/en active IP Right Grant
- 2000-04-07 HU HU0201459A patent/HU226672B1/hu not_active IP Right Cessation
- 2000-04-07 EP EP00923156A patent/EP1169059B1/en not_active Expired - Lifetime
- 2000-04-07 DE DE60023476T patent/DE60023476T2/de not_active Expired - Lifetime
-
2001
- 2001-09-20 ZA ZA200107771A patent/ZA200107771B/en unknown
- 2001-10-04 NO NO20014842A patent/NO332619B1/no not_active IP Right Cessation
-
2002
- 2002-07-02 HK HK02104971.3A patent/HK1043313A1/zh unknown
- 2002-10-17 HK HK02107549.9A patent/HK1046093B/zh not_active IP Right Cessation
-
2012
- 2012-02-21 JP JP2012035366A patent/JP2012136535A/ja active Pending
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