GT200600197A - Compuestos y composiciones como inhibidores de proteina quinasa - Google Patents

Compuestos y composiciones como inhibidores de proteina quinasa

Info

Publication number
GT200600197A
GT200600197A GT200600197A GT200600197A GT200600197A GT 200600197 A GT200600197 A GT 200600197A GT 200600197 A GT200600197 A GT 200600197A GT 200600197 A GT200600197 A GT 200600197A GT 200600197 A GT200600197 A GT 200600197A
Authority
GT
Guatemala
Prior art keywords
compounds
compositions
protein
inhibitors
quinasa inhibitors
Prior art date
Application number
GT200600197A
Other languages
English (en)
Inventor
Advait Nagle
Nathanael Gray
Yi Liu
Pingda Ren
Taebo Sim
Shuli You
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of GT200600197A publication Critical patent/GT200600197A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Abstract

LA PRESENTE INVENCIÓN SE REFIERE A COMPUESTOS DE LA FÓRMULA GENERAL I EN LA QUE R1,R2,R3,R4,R7,Y1,Y2,M,N, SON GRUPOS FUNCIONALES DESCRITOS EN EL EXPEDIENTE. ESTOS COMPUESTOS SON DE UTILIDAD CON EL FIN DE TRATAR O PREVENIR ENFERMEDADES O TRASTORNOS ASOCIADOS CON UNA ACTIVIDAD DE QUINASA ANORMAL O MAL REGULADA.
GT200600197A 2005-05-13 2006-05-10 Compuestos y composiciones como inhibidores de proteina quinasa GT200600197A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US68068405P 2005-05-13 2005-05-13

Publications (1)

Publication Number Publication Date
GT200600197A true GT200600197A (es) 2007-03-28

Family

ID=37074687

Family Applications (1)

Application Number Title Priority Date Filing Date
GT200600197A GT200600197A (es) 2005-05-13 2006-05-10 Compuestos y composiciones como inhibidores de proteina quinasa

Country Status (19)

Country Link
US (1) US8183248B2 (es)
EP (1) EP1891066B1 (es)
JP (1) JP5016593B2 (es)
KR (1) KR20080025039A (es)
CN (1) CN101175753B (es)
AR (1) AR056346A1 (es)
AT (1) ATE492545T1 (es)
AU (1) AU2006247757B2 (es)
BR (1) BRPI0610278A2 (es)
CA (1) CA2607299C (es)
DE (1) DE602006019088D1 (es)
ES (1) ES2358344T3 (es)
GT (1) GT200600197A (es)
MX (1) MX2007014066A (es)
PE (1) PE20061366A1 (es)
PL (1) PL1891066T3 (es)
RU (1) RU2411242C2 (es)
TW (1) TW200726766A (es)
WO (1) WO2006124462A2 (es)

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KR20180088926A (ko) 2012-07-24 2018-08-07 파마싸이클릭스 엘엘씨 브루톤 티로신 키나제(btk)의 억제제에 대한 내성과 관련된 돌연변이
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Also Published As

Publication number Publication date
BRPI0610278A2 (pt) 2010-06-08
JP2008540556A (ja) 2008-11-20
DE602006019088D1 (de) 2011-02-03
TW200726766A (en) 2007-07-16
JP5016593B2 (ja) 2012-09-05
CA2607299A1 (en) 2006-11-23
CN101175753A (zh) 2008-05-07
PE20061366A1 (es) 2007-01-05
AR056346A1 (es) 2007-10-03
AU2006247757A1 (en) 2006-11-23
AU2006247757B2 (en) 2009-08-27
KR20080025039A (ko) 2008-03-19
MX2007014066A (es) 2008-02-11
WO2006124462A3 (en) 2007-01-04
CN101175753B (zh) 2011-03-23
EP1891066A2 (en) 2008-02-27
WO2006124462A2 (en) 2006-11-23
RU2007145935A (ru) 2009-06-20
ES2358344T3 (es) 2011-05-09
RU2411242C2 (ru) 2011-02-10
ATE492545T1 (de) 2011-01-15
EP1891066B1 (en) 2010-12-22
US20090118273A1 (en) 2009-05-07
PL1891066T3 (pl) 2011-05-31
US8183248B2 (en) 2012-05-22
CA2607299C (en) 2013-05-07

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