FR2596062B1 - Anticorps monoclonaux et antigene du carcinome pulmonaire humain a cellules non petites et de certains autres carcinomes humains - Google Patents

Anticorps monoclonaux et antigene du carcinome pulmonaire humain a cellules non petites et de certains autres carcinomes humains

Info

Publication number
FR2596062B1
FR2596062B1 FR878702304A FR8702304A FR2596062B1 FR 2596062 B1 FR2596062 B1 FR 2596062B1 FR 878702304 A FR878702304 A FR 878702304A FR 8702304 A FR8702304 A FR 8702304A FR 2596062 B1 FR2596062 B1 FR 2596062B1
Authority
FR
France
Prior art keywords
human
antigen
certain
monoclonal antibodies
small cells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR878702304A
Other languages
English (en)
Other versions
FR2596062A1 (fr
Inventor
Karl Erik Hellstrom
Joseph P Brown
Ingegerd Hellstrom
Hans Marquard
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Oncogen LP
Original Assignee
Oncogen LP
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oncogen LP filed Critical Oncogen LP
Publication of FR2596062A1 publication Critical patent/FR2596062A1/fr
Application granted granted Critical
Publication of FR2596062B1 publication Critical patent/FR2596062B1/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0693—Tumour cells; Cancer cells
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3023—Lung
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3015—Breast
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3046—Stomach, Intestines
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
    • C12N5/12—Fused cells, e.g. hybridomas
    • C12N5/16—Animal cells
    • C12N5/163—Animal cells one of the fusion partners being a B or a T lymphocyte
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57423—Specifically defined cancers of lung
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • General Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Hospice & Palliative Care (AREA)
  • Food Science & Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
FR878702304A 1986-02-26 1987-02-23 Anticorps monoclonaux et antigene du carcinome pulmonaire humain a cellules non petites et de certains autres carcinomes humains Expired - Fee Related FR2596062B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/834,172 US5185432A (en) 1986-02-26 1986-02-26 Monoclonal antibodies and antigen for human non-small cell lung carcinoma and other certain human carcinomas

Publications (2)

Publication Number Publication Date
FR2596062A1 FR2596062A1 (fr) 1987-09-25
FR2596062B1 true FR2596062B1 (fr) 1990-06-08

Family

ID=25266276

Family Applications (1)

Application Number Title Priority Date Filing Date
FR878702304A Expired - Fee Related FR2596062B1 (fr) 1986-02-26 1987-02-23 Anticorps monoclonaux et antigene du carcinome pulmonaire humain a cellules non petites et de certains autres carcinomes humains

Country Status (28)

Country Link
US (1) US5185432A (fr)
JP (1) JPS62220197A (fr)
KR (2) KR900006338B1 (fr)
CN (1) CN87100927A (fr)
AT (1) AT400577B (fr)
AU (1) AU612967B2 (fr)
BE (1) BE1000611A5 (fr)
CA (1) CA1312025C (fr)
CH (1) CH675880A5 (fr)
DD (2) DD266028A5 (fr)
DE (1) DE3705276A1 (fr)
DK (1) DK98187A (fr)
ES (1) ES2004245A6 (fr)
FI (1) FI870764A (fr)
FR (1) FR2596062B1 (fr)
GB (1) GB2186885B (fr)
GR (1) GR870294B (fr)
IE (1) IE60286B1 (fr)
IT (1) IT1203511B (fr)
LU (1) LU86786A1 (fr)
NL (1) NL8700415A (fr)
NO (1) NO174719C (fr)
NZ (1) NZ219338A (fr)
OA (1) OA08485A (fr)
PT (1) PT84370B (fr)
SE (2) SE467988B (fr)
YU (1) YU46189B (fr)
ZA (1) ZA869494B (fr)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3531301A1 (de) * 1985-09-02 1987-03-05 Behringwerke Ag Monoklonale antikoerper gegen tumorassoziierte glykoproteine, verfahren zu ihrer herstellung sowie ihre verwendung
JPH0813840B2 (ja) * 1987-03-31 1996-02-14 協和醗酵工業株式会社 抗ヒト肺腺癌単クロ−ン性抗体
US5134075A (en) * 1989-02-17 1992-07-28 Oncogen Limited Partnership Monoclonal antibody to novel antigen associated with human tumors
US5171665A (en) * 1989-04-17 1992-12-15 Oncogen Monoclonal antibody to novel antigen associated with human tumors
US5342774A (en) * 1991-05-23 1994-08-30 Ludwig Institute For Cancer Research Nucleotide sequence encoding the tumor rejection antigen precursor, MAGE-1
US5589579A (en) * 1994-07-19 1996-12-31 Cytoclonal Pharmaceutics, Inc. Gene sequence and probe for a marker of non-small cell lung carinoma
DE69831522T2 (de) 1997-03-03 2006-06-14 Amersham Biosciences Uk Ltd In-situ Zellextraktion und Assay-Verfahren
DE19725133A1 (de) * 1997-06-13 1998-12-17 Micromet Ges Fuer Biomedizinis Nachweis von seltenen Zellen
US20050089918A1 (en) * 1998-02-23 2005-04-28 Amersham Biosciences Uk Limited In-situ cell extraction and assay method
US6117981A (en) * 1999-06-03 2000-09-12 Cytoclonal Pharmaceutics, Inc. Hybridomas for lung cancer marker and monoclonal antibodies thereof
AU7337400A (en) * 1999-09-03 2001-04-10 Human Genome Sciences, Inc. B7-like polynucleotides, polypeptides, and antibodies
WO2001094413A2 (fr) 2000-06-06 2001-12-13 Bristol-Myers Squibb Company Acides nucleiques et polypeptides apparentes a b7 utiles pour effectuer une immunomodulation
TWI317285B (en) * 2000-07-28 2009-11-21 Dainippon Sumitomo Pharma Co New use and kit for remedies for cancer
CN101724072B (zh) * 2008-10-27 2013-10-09 谷为岳 一种抗肿瘤的单克隆抗体的序列及应用
GB0916686D0 (en) * 2009-09-23 2009-11-04 Univ Manchester Metropolitan Treatment of cancer
US8802091B2 (en) 2010-03-04 2014-08-12 Macrogenics, Inc. Antibodies reactive with B7-H3 and uses thereof
SG183847A1 (en) 2010-03-04 2012-10-30 Macrogenics Inc Antibodies reactive with b7-h3, immunologically active fragments thereof and uses thereof
CN105424942B (zh) * 2010-09-17 2017-07-18 国立研究开发法人产业技术综合研究所 肺癌鉴定标志物
CN102391992B (zh) * 2011-11-03 2012-08-29 潘世扬 抗人非小细胞肺癌单克隆抗体及其应用
EP3442574A4 (fr) 2016-04-15 2019-12-11 MacroGenics, Inc. Nouvelles molécules de liaison à b7-h3, leurs conjugués anticorps-médicaments et leurs procédés d'utilisation
CN111662371B (zh) * 2020-04-30 2023-07-04 美康生物科技股份有限公司 细胞角蛋白19片段抗原及其制备方法和应用
CN112300284B (zh) * 2020-12-29 2021-04-06 慈达(广州)生物技术有限公司 核酸筛选结合抗体检测用于癌症检测中的用途及其制备的试剂盒

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4569788A (en) * 1983-05-18 1986-02-11 The United States Of America As Represented By The Department Of Health And Human Services Monoclonal antibodies against non small cell lung cancer
ZA858371B (en) * 1984-11-02 1987-03-25 Oncogen Monoclonal antibodies for human non-small cell lung carcinomas
IL76877A (en) * 1984-11-02 1991-11-21 Oncogen Diagnostic method for the determination of human non-small cell lung carcinomas employing novel monoclonal antibodies and compositions containing said antibodies

Also Published As

Publication number Publication date
YU25787A (en) 1990-12-31
KR870008026A (ko) 1987-09-23
NO870770L (no) 1987-08-27
BE1000611A5 (fr) 1989-02-21
AU6927287A (en) 1987-08-27
DK98187A (da) 1987-08-27
NZ219338A (en) 1991-11-26
ATA43587A (de) 1995-06-15
IT1203511B (it) 1989-02-15
AU612967B2 (en) 1991-07-25
GB2186885B (en) 1990-10-03
SE9201529A0 (sv) 1992-05-14
IE870487L (en) 1987-08-26
SE8700805D0 (sv) 1987-02-25
NO174719C (no) 1994-06-22
CN87100927A (zh) 1988-10-05
SE8700805L (sv) 1987-10-22
PT84370A (en) 1987-03-01
NO870770D0 (no) 1987-02-25
SE467988B (sv) 1992-10-12
NO174719B (no) 1994-03-14
GR870294B (en) 1987-06-30
AT400577B (de) 1996-01-25
GB2186885A (en) 1987-08-26
DK98187D0 (da) 1987-02-25
CH675880A5 (fr) 1990-11-15
DD266028A5 (de) 1989-03-22
NL8700415A (nl) 1987-09-16
CA1312025C (fr) 1992-12-29
DE3705276A1 (de) 1987-08-27
IT8719491A0 (it) 1987-02-25
FR2596062A1 (fr) 1987-09-25
OA08485A (fr) 1988-07-29
KR880010438A (ko) 1988-10-08
FI870764A (fi) 1987-08-27
ES2004245A6 (es) 1988-12-16
KR900006338B1 (ko) 1990-08-28
JPS62220197A (ja) 1987-09-28
YU46189B (sh) 1993-05-28
PT84370B (pt) 1989-11-10
LU86786A1 (fr) 1987-09-15
US5185432A (en) 1993-02-09
IE60286B1 (en) 1994-06-29
FI870764A0 (fi) 1987-02-23
GB8703700D0 (en) 1987-03-25
SE9201529D0 (sv) 1992-05-14
ZA869494B (en) 1987-10-28
DD276165A5 (de) 1990-02-14

Similar Documents

Publication Publication Date Title
FR2596062B1 (fr) Anticorps monoclonaux et antigene du carcinome pulmonaire humain a cellules non petites et de certains autres carcinomes humains
ZA859761B (en) Monoclonal antibodies and antigen for human non-small cell lung carcinomas
DK323486D0 (da) Monoklont antistof mod et med human carcinom associeret antigen
ZA853025B (en) Isolation of proteins of htlv-iii,serological detection of antibodies to htlv-iii in sera of patients with aids and pre-aids conditions,and detection of htlv-iii infection by immuno-assays using htlv-iii and its proteins
GB2196634B (en) Monoclonal antibodies to hiv and related peptides
FR2499414B1 (fr) Production d'anticorps proteiniques humains
DE3584035D1 (de) Nachweis von menschlichem cytomegalovirus-spezifischem igm.
FR2631239B1 (fr) Anticorps monoclonal humain et hybridome le produisant
DE3477845D1 (en) Lewis blood group phenotype assay
GB2182949A (en) Monoclonal antibodies and antigens for human non-small cell lung carcinomas
RO92427A (fr) Anticorps monoclonaux pour la detection des cellules malignes et procede d'obtention
NZ220803A (en) Composite immunogen consisting of t and b cell epitopes of hepatitis b surface antigen
IT7848508A0 (it) Antigeni e anticorpi della teofillina
AU550364B2 (en) Immunogen of lidocaine-protein conjugate and antibodies derived therefrom
IL61641A0 (en) Immunological detection of human cancer cells and antigens and antibodies for use therein
DE3689948D1 (de) Monoklonale antikörper und testverfahren.
EP0210029A3 (en) Monoclonal antibodies to human plasma prekallikrein and methods of preparing and using same
EP0269526A3 (en) Method of quantitative determination of antigens and antibodies
EP0190711A3 (en) Monoclonal antibodies to tissue plasminogen activator derived from human normal cells
KR880701561A (ko) 피브린에 대한 단클론의 항체
ZA871979B (en) Detection of haptens in immunoassay techniques
KR860005021A (ko) HBc 항원의 정재방법 및 정제된 HBc 항원을 이용한 HBc 항체의 측정방법
GB8804802D0 (en) Preparation of monoclonal antibodies
IL86960A0 (en) Preparation of human monoclonal antibodies
FR2621127B1 (fr) Anticorps monoclonal reconnaissant un epitope de la chaine gamma des recepteurs de surface des cellules t humaines, lignee de cellules d'hybridomes produisant cet anticorps, et utilisation de cet anticorps monoclonal

Legal Events

Date Code Title Description
ST Notification of lapse