FR2401914A1 - Nouveaux composes heterocycliques, procede pour leur preparation et compositions medicinales contenant lesdits composes - Google Patents

Nouveaux composes heterocycliques, procede pour leur preparation et compositions medicinales contenant lesdits composes

Info

Publication number
FR2401914A1
FR2401914A1 FR7824926A FR7824926A FR2401914A1 FR 2401914 A1 FR2401914 A1 FR 2401914A1 FR 7824926 A FR7824926 A FR 7824926A FR 7824926 A FR7824926 A FR 7824926A FR 2401914 A1 FR2401914 A1 FR 2401914A1
Authority
FR
France
Prior art keywords
compounds
preparation
compositions containing
medicinal compositions
new heterocyclic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7824926A
Other languages
English (en)
Other versions
FR2401914B1 (fr
Inventor
Yasufumi Hirata
Isao Yanagisawa
Toshinari Tamura
Massaki Takeda
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yamanouchi Pharmaceutical Co Ltd
Original Assignee
Yamanouchi Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP10407977A external-priority patent/JPS5444660A/ja
Priority claimed from JP8694478A external-priority patent/JPS5515415A/ja
Application filed by Yamanouchi Pharmaceutical Co Ltd filed Critical Yamanouchi Pharmaceutical Co Ltd
Publication of FR2401914A1 publication Critical patent/FR2401914A1/fr
Application granted granted Critical
Publication of FR2401914B1 publication Critical patent/FR2401914B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/86—Hydrazides; Thio or imino analogues thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
    • C07D213/32—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/63—One oxygen atom
    • C07D213/68—One oxygen atom attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D277/26—Radicals substituted by sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/52—Radicals substituted by nitrogen atoms not forming part of a nitro radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

La présente invention concerne de nouveaux composés hétérocycliques, un procédé pour leur préparation et des compositions médicinales contenant lesdits composés. Les composés hétérocycliques sont représentés par la formule :
FR7824926A 1977-08-29 1978-08-29 Nouveaux composes heterocycliques, procede pour leur preparation et compositions medicinales contenant lesdits composes Granted FR2401914A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP10407977A JPS5444660A (en) 1977-08-29 1977-08-29 Heterocyclic compound and its preparation
JP8694478A JPS5515415A (en) 1978-07-17 1978-07-17 Heterocyclic compound and its preparation

Publications (2)

Publication Number Publication Date
FR2401914A1 true FR2401914A1 (fr) 1979-03-30
FR2401914B1 FR2401914B1 (fr) 1981-05-08

Family

ID=26428021

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7824926A Granted FR2401914A1 (fr) 1977-08-29 1978-08-29 Nouveaux composes heterocycliques, procede pour leur preparation et compositions medicinales contenant lesdits composes

Country Status (7)

Country Link
US (1) US4379158A (fr)
CA (1) CA1125298A (fr)
DE (1) DE2835695A1 (fr)
FR (1) FR2401914A1 (fr)
GB (1) GB2003471B (fr)
IT (1) IT1113092B (fr)
SE (1) SE7809035L (fr)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR228941A1 (es) * 1978-04-26 1983-05-13 Glaxo Group Ltd Procedimiento para preparar nuevos derivados de 3,5-diamino-1,2,4-triazol que son activos contra receptores histaminicos
PH18379A (en) * 1979-03-02 1985-06-19 Glaxo Group Ltd Triazole acylamines and pharmaceutical compositions thereof
JPS55120571A (en) * 1979-03-02 1980-09-17 Glaxo Group Ltd Heterocyclic derivative
JPS568352A (en) * 1979-07-03 1981-01-28 Shionogi & Co Ltd Aminoalkylvenzene derivative
EP0028483B1 (fr) * 1979-10-22 1984-04-18 Glaxo Group Limited Dérivés de 1,2,4-triazole, procédés pour leur préparation et compositions pharmaceutiques les contenant
US4238487A (en) 1979-10-31 1980-12-09 Merck & Co., Inc. Aminoalkyl benzofuran derivatives
CH655104A5 (fr) * 1980-02-28 1986-03-27 Glaxo Group Ltd Derives heterocycliques triazoliques, procedes pour leur preparation et compositions pharmaceutiques les comportant.
JPS5775976A (en) * 1980-08-27 1982-05-12 Glaxo Group Ltd Novel heterocyclic derivative, manufacture and medicinal composition containing same
US4375547A (en) * 1980-10-02 1983-03-01 Eli Lilly And Company N-Methyl-N'-2-([(2-dimethylaminomethyl)-4-thiazolyl]methylthio)ethyl 2-nitro-1,1-ethenediamine
CA1209998A (fr) * 1981-03-09 1986-08-19 David J. Gilman Derives amides inhibiteurs des recepteurs h.sub.2 de l'histamine
IN158869B (fr) * 1981-03-18 1987-02-07 Ici Plc
EP0067508B1 (fr) * 1981-05-18 1985-10-30 Imperial Chemical Industries Plc Dérivés d'amidine
FR2509305B1 (fr) * 1981-07-08 1986-04-18 Sanofi Sa Benzamides, procede pour leur preparation et compositions pharmaceutiques les renfermant
AU547405B2 (en) * 1981-07-08 1985-10-17 Sanofi Amidobenzamides
US4808589A (en) * 1982-02-20 1989-02-28 Smith Kline & French Laboratories Limited Pyrimidone derivatives
EP0089153B1 (fr) * 1982-03-17 1986-09-24 Smith Kline & French Laboratories Limited Dérivés de pyridine
DE3224984A1 (de) * 1982-07-03 1984-01-05 Bayer Ag, 5090 Leverkusen Substituierte diphenylether, verfahren zu ihrer herstellung und ihre verwendung als herbizide
US4496737A (en) * 1982-09-27 1985-01-29 Merck & Co., Inc. Process for preparing sulfamylamidine antisecretory agents
US4837316A (en) * 1985-08-29 1989-06-06 Fujirebio Kabushiki Kaisha Alkylamide derivatives with H2 -receptor antagonistic and cytoprotective action
US4829081A (en) * 1986-01-07 1989-05-09 Sandoz Pharm. Corp. Analogs of mevalonolactone and derivatives thereof
US4927851A (en) * 1986-01-07 1990-05-22 Sandoz Pharm. Corp. Analogs of mevalonolactone and derivatives thereof
DE3631334A1 (de) * 1986-09-15 1988-03-17 Heumann Pharma Gmbh & Co Neue imidazolylguanidinderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
JP2608439B2 (ja) * 1988-01-25 1997-05-07 三菱レイヨン株式会社 耐衝撃性樹脂組成物
DE4404916A1 (de) * 1994-02-16 1995-08-17 Steinecker Anton Entwicklung Drehvorrichtung zum Lagern von Behältern
WO2022034121A1 (fr) 2020-08-11 2022-02-17 Université De Strasbourg Bloqueurs de h2 ciblant des macrophages du foie pour la prévention et le traitement d'une maladie du foie et du cancer

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3558640A (en) * 1967-12-20 1971-01-26 Merck & Co Inc Certain pyridyl and thiazolyl methylthiopropionic acids and derivatives
US4104382A (en) * 1972-04-20 1978-08-01 Smith Kline & French Laboratories Limited Pharmaceutical compositions and methods of inhibiting H-1 and H-2 histamine receptors
GB1398426A (en) 1972-09-05 1975-06-18 Smith Kline French Lab Heterocyclic substituted guanidines

Also Published As

Publication number Publication date
GB2003471B (en) 1982-04-07
CA1125298A (fr) 1982-06-08
FR2401914B1 (fr) 1981-05-08
GB2003471A (en) 1979-03-14
SE7809035L (sv) 1979-03-01
DE2835695A1 (de) 1979-03-15
IT1113092B (it) 1986-01-20
US4379158A (en) 1983-04-05
IT7826925A0 (it) 1978-08-22

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Legal Events

Date Code Title Description
ST Notification of lapse