FI922099A - Foereningar - Google Patents

Foereningar Download PDF

Info

Publication number: FI922099A
Authority: FI; Finland
Prior art keywords: alkyl; opt; substd; phenyl; ring
Prior art date: 1991-05-09

Application number

FI922099A

Other languages

English (en)

Other versions

FI922099A0 (fi

FI102754B (fi

FI102754B1 (fi

Inventor

Thomas Michael Bare

Richard Bruce Sparks

Original Assignee

Ici Plc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-05-09

Filing date

1992-05-08

Publication date

1992-11-10

1991-05-09 Priority claimed from GB919109973A external-priority patent/GB9109973D0/en

1992-02-13 Priority claimed from GB929202991A external-priority patent/GB9202991D0/en

1992-05-08 Application filed by Ici Plc filed Critical Ici Plc

1992-05-08 Publication of FI922099A0 publication Critical patent/FI922099A0/fi

1992-11-10 Publication of FI922099A publication Critical patent/FI922099A/fi

1999-02-15 Application granted granted Critical

1999-02-15 Publication of FI102754B publication Critical patent/FI102754B/fi

1999-02-15 Publication of FI102754B1 publication Critical patent/FI102754B1/fi

Links

125000000217 alkyl group Chemical group 0.000 abstract 11
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 5
125000001475 halogen functional group Chemical group 0.000 abstract 2
125000004076 pyridyl group Chemical group 0.000 abstract 2
150000003839 salts Chemical class 0.000 abstract 2
208000012902 Nervous system disease Diseases 0.000 abstract 1
208000025966 Neurological disease Diseases 0.000 abstract 1
238000005917 acylation reaction Methods 0.000 abstract 1
125000003545 alkoxy group Chemical group 0.000 abstract 1
238000005804 alkylation reaction Methods 0.000 abstract 1
125000004432 carbon atom Chemical group C* 0.000 abstract 1
125000001559 cyclopropyl group Chemical group [H]C1([H])C([H])([H])C1([H])* 0.000 abstract 1
239000003085 diluting agent Substances 0.000 abstract 1
125000000717 hydrazino group Chemical group [H]N([*])N([H])[H] 0.000 abstract 1
125000001449 isopropyl group Chemical group [H]C([H])([H])C([H])(*)C([H])([H])[H] 0.000 abstract 1
125000005010 perfluoroalkyl group Chemical group 0.000 abstract 1
BOYBQQBDCOIBIR-UHFFFAOYSA-N pyrido[2,3-f]cinnoline Chemical compound N1=CC=C2C3=NC=CC=C3C=CC2=N1 BOYBQQBDCOIBIR-UHFFFAOYSA-N 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/50—Pyridazines; Hydrogenated pyridazines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/50—Pyridazines; Hydrogenated pyridazines
- A61K31/5025—Pyridazines; Hydrogenated pyridazines ortho- or peri-condensed with heterocyclic ring systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/14—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D495/14—Ortho-condensed systems

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Epidemiology (AREA)
Neurology (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Psychiatry (AREA)
Hospice & Palliative Care (AREA)
Urology & Nephrology (AREA)
Vascular Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Saccharide Compounds (AREA)

FI922099A 1991-05-09 1992-05-08 Menetelmä terapeuttisesti käyttökelpoisten pyridatsino[4,5-b]kinoliinien tai niiden alkyyli- tai asyylijohdannaisten valmistamiseksi FI102754B1 (fi)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
GB9109973		1991-05-09
GB919109973A GB9109973D0 (en)	1991-05-09	1991-05-09	Therapeutic compositions
GB929202991A GB9202991D0 (en)	1992-02-13	1992-02-13	Compounds
GB9202991		1992-02-13

Publications (4)

Publication Number	Publication Date
FI922099A0 FI922099A0 (fi)	1992-05-08
FI922099A true FI922099A (fi)	1992-11-10
FI102754B FI102754B (fi)	1999-02-15
FI102754B1 FI102754B1 (fi)	1999-02-15

Family

ID=26298868

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI922099A FI102754B1 (fi)	1991-05-09	1992-05-08	Menetelmä terapeuttisesti käyttökelpoisten pyridatsino[4,5-b]kinoliinien tai niiden alkyyli- tai asyylijohdannaisten valmistamiseksi

Country Status (21)

Country	Link
US (4)	US5604227A (fi)
EP (1)	EP0516297B1 (fi)
JP (1)	JP3279633B2 (fi)
KR (1)	KR100231095B1 (fi)
AT (1)	ATE144707T1 (fi)
AU (1)	AU642086B2 (fi)
CA (1)	CA2067537A1 (fi)
CZ (1)	CZ286814B6 (fi)
DE (1)	DE69214881T2 (fi)
DK (1)	DK0516297T3 (fi)
ES (1)	ES2093782T3 (fi)
FI (1)	FI102754B1 (fi)
GB (1)	GB9208511D0 (fi)
GR (1)	GR3021512T3 (fi)
HU (2)	HUT61302A (fi)
IE (1)	IE921294A1 (fi)
IL (1)	IL101711A0 (fi)
MY (1)	MY108482A (fi)
NO (1)	NO180619C (fi)
NZ (1)	NZ242540A (fi)
SK (1)	SK280336B6 (fi)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2676053B1 (fr) *	1991-05-03	1993-08-27	Sanofi Elf	Nouveaux composes dialkylenepiperidino et leurs enantiomeres, procede pour leur preparation et compositions pharmaceutiques les contenant.
GB9208511D0 (en) *	1991-05-09	1992-06-03	Ici Plc	Compounds
CA2115792C (en)	1993-03-05	2005-11-01	David J. Mayer	Method for the treatment of pain
US5834479A (en) *	1993-03-05	1998-11-10	Mayer; David J.	Method and composition for alleviating pain
IL111266A (en) *	1993-10-22	2002-03-10	Zeneca Ltd	2-HETEROARYL OR 2-ARYLPYRIDAZINO [4,5-b] QUINOLINE - 1, 10 - DIONES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
GB9411955D0 (en) *	1994-06-15	1994-08-03	Merck Sharp & Dohme	Therapeutic agents
GB9422894D0 (en) *	1994-11-12	1995-01-04	Zeneca Ltd	Pyridazino quinoline compounds
US6214826B1 (en)	1994-11-12	2001-04-10	Zeneca Limited	Pyridazino quinoline compounds
GB9507318D0 (en) *	1995-04-07	1995-05-31	Zeneca Ltd	Alpha substituted pyridazino quinoline compounds
US5776935A (en) *	1996-07-25	1998-07-07	Merz & Co. Gmbh & Co.	Pyrido-phtalazin diones and their use against neurological disorders associated with excitotoxicity and malfunctioning of glutamatergic neurotransmission
US6861442B1 (en) *	1998-12-30	2005-03-01	Sugen, Inc.	PYK2 and inflammation
ES2203443T3 (es) *	1999-03-31	2004-04-16	Basf Aktiengesellschaft	Compuestos de anilina substituidos.
US6417394B2 (en) *	2000-04-05	2002-07-09	Bristol Myers Squibb Pharma Company	Specific salt forms of triphenylethylene derivatives as selective estrogen receptor modulators
KR100965861B1 (ko)	2002-10-24	2010-06-24	삼성전자주식회사	이동통신 시스템에서 복합 재전송 제어 장치
GB0525068D0 (en) *	2005-12-08	2006-01-18	Novartis Ag	Organic compounds

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9208511D0 (en) *	1991-05-09	1992-06-03	Ici Plc	Compounds

1992
- 1992-04-16 GB GB929208511A patent/GB9208511D0/en active Pending
- 1992-04-22 IE IE129492A patent/IE921294A1/en not_active IP Right Cessation
- 1992-04-28 AU AU15213/92A patent/AU642086B2/en not_active Ceased
- 1992-04-28 IL IL101711A patent/IL101711A0/xx unknown
- 1992-04-28 MY MYPI92000780A patent/MY108482A/en unknown
- 1992-04-29 NZ NZ242540A patent/NZ242540A/en unknown
- 1992-04-29 CA CA002067537A patent/CA2067537A1/en not_active Abandoned
- 1992-05-04 HU HU9201486A patent/HUT61302A/hu unknown
- 1992-05-06 DE DE69214881T patent/DE69214881T2/de not_active Expired - Fee Related
- 1992-05-06 ES ES92304084T patent/ES2093782T3/es not_active Expired - Lifetime
- 1992-05-06 AT AT92304084T patent/ATE144707T1/de not_active IP Right Cessation
- 1992-05-06 EP EP92304084A patent/EP0516297B1/en not_active Expired - Lifetime
- 1992-05-06 DK DK92304084.4T patent/DK0516297T3/da active
- 1992-05-07 CZ CS19921396A patent/CZ286814B6/cs not_active IP Right Cessation
- 1992-05-07 SK SK1396-92A patent/SK280336B6/sk unknown
- 1992-05-08 FI FI922099A patent/FI102754B1/fi active
- 1992-05-08 NO NO921841A patent/NO180619C/no not_active IP Right Cessation
- 1992-05-08 KR KR1019920007938A patent/KR100231095B1/ko not_active IP Right Cessation
- 1992-05-11 JP JP11728592A patent/JP3279633B2/ja not_active Expired - Fee Related
1995
- 1995-04-13 US US08/421,133 patent/US5604227A/en not_active Expired - Lifetime
- 1995-04-24 US US08/427,469 patent/US5599814A/en not_active Expired - Lifetime
- 1995-06-23 HU HU95P/P00416P patent/HU211149A9/hu unknown
1996
- 1996-08-05 US US08/689,259 patent/US5733910A/en not_active Expired - Lifetime
- 1996-08-15 US US08/700,654 patent/US5739133A/en not_active Expired - Fee Related
- 1996-10-31 GR GR960402628T patent/GR3021512T3/el unknown

Also Published As

Publication number	Publication date
NO180619C (no)	1997-05-21
EP0516297A1 (en)	1992-12-02
KR100231095B1 (ko)	1999-11-15
US5599814A (en)	1997-02-04
GB9208511D0 (en)	1992-06-03
EP0516297B1 (en)	1996-10-30
AU1521392A (en)	1992-11-12
HUT61302A (en)	1992-12-28
NZ242540A (en)	1994-10-26
GR3021512T3 (en)	1997-01-31
NO180619B (no)	1997-02-10
US5739133A (en)	1998-04-14
ATE144707T1 (de)	1996-11-15
CA2067537A1 (en)	1992-11-10
KR920021147A (ko)	1992-12-18
IE921294A1 (en)	1992-11-18
DE69214881T2 (de)	1997-03-13
FI922099A0 (fi)	1992-05-08
AU642086B2 (en)	1993-10-07
HU9201486D0 (en)	1992-07-28
ES2093782T3 (es)	1997-01-01
US5733910A (en)	1998-03-31
JPH05140162A (ja)	1993-06-08
DK0516297T3 (da)	1997-04-07
NO921841L (no)	1992-11-10
US5604227A (en)	1997-02-18
IL101711A0 (en)	1992-12-30
SK280336B6 (sk)	1999-12-10
HU211149A9 (en)	1995-10-30
FI102754B (fi)	1999-02-15
FI102754B1 (fi)	1999-02-15
MY108482A (en)	1996-09-30
DE69214881D1 (de)	1996-12-05
NO921841D0 (no)	1992-05-08
CZ286814B6 (cs)	2000-07-12
CS139692A3 (en)	1992-11-18
JP3279633B2 (ja)	2002-04-30

Publication	Publication Date	Title
FI922099A (fi)	1992-11-10	Foereningar
TW229156B (fi)	1994-09-01
AU587623B2 (en)	1989-08-24	Herbicidal 5-imidazole carboxylic acid derivatives
GR1000462B (el)	1992-07-30	Διαδικασια για την παρασκευη των παραγωγων του cephem και των ενδιαμεσων αυτου.
DK0467564T3 (da)	1996-05-13	Behandling af inflammatoriske sygdomme med 15-ketoprostaglandinforbindelser
HK186696A (en)	1996-10-11	Substituted imidazobenzaze-pines and imidazopyridoaze-pines
JPS57176988A (en)	1982-10-30	Penam-3-carboxylic acid derivative and its preparation
FI915245A (fi)	1992-05-10	7-acyl-3-(substitueradkarbamoyloxi) cefemfoereningar samt foerfarande foer framstaellning av dessa.
JPS5618967A (en)	1981-02-23	Azolyllalkenol* its manufacture and its use as bactericide
EP0675127A4 (en)	1995-08-08	CHINOLINE CARBONIC ACID DERIVATIVES AND METHOD FOR THE PRODUCTION THEREOF.
ES8604556A1 (es)	1986-02-01	Procedimiento para preparar derivados de flaveno y tioflave-no
SE8006142L (sv)	1981-03-05	1,2,4-triazol-3-tioler
FR2021123A1 (fr)	1970-07-17	Nouveaux derives du 1,3-diamino-propane-2-ol
FR2267102A1 (en)	1975-11-07	2,6-Di(branched alkylamino)pyridines - for treatment of fatty degeneration and diabetes
SE8005425L (sv)	1981-02-02	2-amino-3-(alkyltiobenzoyl)-fenylettiksyror
GB1198853A (en)	1970-07-15	Adamante Derivatives
EP0148007A3 (en)	1986-04-02	Cephalosporin compounds and medicaments and their production
CY1423A (en)	1988-09-02	Novel amidines,processes for their manufacture,pharmaceutical preparations containing them,and their use
GB1095783A (en)	1967-12-20	Process for preparing troponeimines
SU1088319A1 (ru)	2006-12-27	2-Ацетилгидразино-4-(3,4-диоксифенил)-тиазол, проявляющий антимикробную активность в отношении кишечной палочки и золотистого стафилококка
JPS5337689A (en)	1978-04-06	Compounds having antibacterial activity
DE3869197D1 (de)	1992-04-23	Hydroxyalkyl-triazolyl-derivate.
ATA502477A (de)	1978-03-15	Verfahren zur herstellung von neuen n-acylamino-alfa-arylacetamidocephalosporinderivaten und deren salzen
GB1187779A (en)	1970-04-15	Dihydrobenzofuran Derivatives
NL7510483A (en)	1977-03-08	Alpha-ureido-thienylacetamido-cephalosporanic acids - with broad-spectrum antibacterial activity for oral or parenteral admin., for disinfection and as additives for animal feeds