ES8308832A1 - Procedimiento para preparar derivados fluorados de diaminohepteno o -heptina. - Google Patents

Procedimiento para preparar derivados fluorados de diaminohepteno o -heptina.

Info

Publication number
ES8308832A1
ES8308832A1 ES515094A ES515094A ES8308832A1 ES 8308832 A1 ES8308832 A1 ES 8308832A1 ES 515094 A ES515094 A ES 515094A ES 515094 A ES515094 A ES 515094A ES 8308832 A1 ES8308832 A1 ES 8308832A1
Authority
ES
Spain
Prior art keywords
heptene
diamino
heptyne
derivatives
fluorinated
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES515094A
Other languages
English (en)
Other versions
ES515094A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merrell Toraude et Cie
Original Assignee
Merrell Toraude et Cie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Toraude et Cie filed Critical Merrell Toraude et Cie
Publication of ES515094A0 publication Critical patent/ES515094A0/es
Publication of ES8308832A1 publication Critical patent/ES8308832A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00—Compounds containing amino groups bound to a carbon skeleton
    • C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
    • C07C211/02—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
    • C07C211/09—Diamines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/15—Oximes (>C=N—O—); Hydrazines (>N—N<); Hydrazones (>N—N=) ; Imines (C—N=C)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/0803—Compounds with Si-C or Si-Si linkages
    • C07F7/081—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE DERIVADOS FLUORADOS DE DIAMINO-HEPTENO O -HEPTINA Y DE SUS SALES FISIOLOGICAMENTE COMPATIBLES, DE FORMULA (I), EN LA QUE P VALE 1 O 2; E Y ES CH<2=CH- O CH=C-. CONSISTE EN LA REACCION DE ALQUILACION DE UN DERIVADO AMINO- Y ACETILENO- PROTEGIDO DE PROPARGILAMINA CON UN DERIVADO AMINO- PROTEGIDO DE UN HALURO DE FORMULA (II) EN LA QUE P VALE 1 O 2 Y X ES CLORO, BROMO O YODO; SEGUIDA DE LA EVENTUAL REDUCCION Y SEPARACION DE LOS GRUPOS PROTECTORES. LA ALQUILACION SE LLEVA A CABO EN UN DISOLVENTE INERTE A UNA TEMPERATURA NO SUPERIOR A -70 C. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS PARA EL CONTROL DEL CRECIMIENTO O PROLIFERACION CELULAR INDESEABLE.
ES515094A 1981-08-19 1982-08-18 Procedimiento para preparar derivados fluorados de diaminohepteno o -heptina. Expired ES8308832A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8125357 1981-08-19

Publications (2)

Publication Number Publication Date
ES515094A0 ES515094A0 (es) 1983-10-16
ES8308832A1 true ES8308832A1 (es) 1983-10-16

Family

ID=10524041

Family Applications (1)

Application Number Title Priority Date Filing Date
ES515094A Expired ES8308832A1 (es) 1981-08-19 1982-08-18 Procedimiento para preparar derivados fluorados de diaminohepteno o -heptina.

Country Status (17)

Country Link
EP (1) EP0072760B1 (es)
JP (1) JPS5841844A (es)
KR (1) KR890000795B1 (es)
AT (1) ATE29487T1 (es)
AU (1) AU548094B2 (es)
CA (1) CA1202985A (es)
DE (1) DE3277199D1 (es)
DK (1) DK161021C (es)
ES (1) ES8308832A1 (es)
GB (1) GB2104073B (es)
GR (1) GR77601B (es)
IE (1) IE54304B1 (es)
IL (1) IL66569A0 (es)
NO (1) NO153005C (es)
NZ (1) NZ201588A (es)
PH (1) PH18003A (es)
ZA (1) ZA825898B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4421768A (en) 1982-08-11 1983-12-20 Merrell Toraude Et Compagnie Fluorinated diamino-heptene and-heptyne derivatives
JPS60117791U (ja) * 1984-01-18 1985-08-09 有限会社　名倉製作所 カ−テン吊具
US4707498A (en) * 1986-01-14 1987-11-17 Merrell Dow Pharmaceuticals Inc. Fluorinated diaminoalkyne derivatives

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4139563A (en) * 1977-07-01 1979-02-13 Merrell Toraude Et Compagnie α-ACETYLENIC DERIVATIVES OF AMINES
US4173971A (en) * 1977-08-29 1979-11-13 Karz Allen E Continuous electrocardiogram monitoring method and system for cardiac patients
US4134918A (en) * 1977-09-06 1979-01-16 Merrell Toraude Et Compagnie Alpha-halomethyl derivatives of amines

Also Published As

Publication number Publication date
NO153005B (no) 1985-09-23
ES515094A0 (es) 1983-10-16
IE821944L (en) 1983-02-19
DK161021B (da) 1991-05-21
NO153005C (no) 1986-01-02
GR77601B (es) 1984-09-25
GB2104073B (en) 1985-02-06
GB2104073A (en) 1983-03-02
AU548094B2 (en) 1985-11-21
CA1202985A (en) 1986-04-08
IE54304B1 (en) 1989-08-16
NO822809L (no) 1983-02-21
ATE29487T1 (de) 1987-09-15
DK161021C (da) 1991-10-28
PH18003A (en) 1985-02-28
NZ201588A (en) 1985-02-28
EP0072760A1 (en) 1983-02-23
EP0072760B1 (en) 1987-09-09
JPH0244298B2 (es) 1990-10-03
AU8724382A (en) 1983-02-24
JPS5841844A (ja) 1983-03-11
KR890000795B1 (ko) 1989-04-07
DE3277199D1 (de) 1987-10-15
ZA825898B (en) 1983-07-27
DK370782A (da) 1983-02-20
KR840001122A (ko) 1984-03-28
IL66569A0 (en) 1982-12-31

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970401