ES8707709A1 - Un procedimiento para producir derivados cristalinos de acido 3-acil o haloacil-amino-4-trimetilaminobutilico - Google Patents

Un procedimiento para producir derivados cristalinos de acido 3-acil o haloacil-amino-4-trimetilaminobutilico

Info

Publication number
ES8707709A1
ES8707709A1 ES557181A ES557181A ES8707709A1 ES 8707709 A1 ES8707709 A1 ES 8707709A1 ES 557181 A ES557181 A ES 557181A ES 557181 A ES557181 A ES 557181A ES 8707709 A1 ES8707709 A1 ES 8707709A1
Authority
ES
Spain
Prior art keywords
aminocarnitines
utility
acylated
compounds
unacylated
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES557181A
Other languages
English (en)
Other versions
ES557181A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cornell Research Foundation Inc
Original Assignee
Cornell Research Foundation Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cornell Research Foundation Inc filed Critical Cornell Research Foundation Inc
Publication of ES8707709A1 publication Critical patent/ES8707709A1/es
Publication of ES557181A0 publication Critical patent/ES557181A0/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/22—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from lactams, cyclic ketones or cyclic oximes, e.g. by reactions involving Beckmann rearrangement
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/26—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having more than one amino group bound to the carbon skeleton, e.g. lysine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/45—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
    • C07C233/46—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
    • C07C233/47—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

PROCEDIMIENTO DE PREPARAR ACETILAMINO. COMPRENDE: A) ESTERIFICAR EL GRUPO B-CARBOXILICO DEL ACIDO D-ASPARTICO CON ALCOHOL BENCILICO; B) PROTEGENER EL GRUPO AMINO DEL COMPUESTO DE (A) CON BENCILOXICARBONILO; C) HACER REACCIONAR EL COMPUESTO DE (B) CON DICICLOHEXILCARBOIMIDA Y DIMETILAMINA PARA FORMAR LA A-DIMETILAMINA; D) REDUCIR SELECTIVAMENTE EN LA PORCION (1) DE LA CADENA DEL COMPUESTO DE (C) CON BOROHIDRURO DE TETRABUTILAMONIO; Y E) METILAR EL COMPUESTO DE D) CON CH3I PARA FORMAR EL ACETILAMINO.
ES557181A 1984-04-02 1986-11-03 Un procedimiento para producir derivados cristalinos de acido 3-acil o haloacil-amino-4-trimetilaminobutilico Expired ES8707709A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US59618084A 1984-04-02 1984-04-02

Publications (2)

Publication Number Publication Date
ES8707709A1 true ES8707709A1 (es) 1987-08-16
ES557181A0 ES557181A0 (es) 1987-08-16

Family

ID=24386277

Family Applications (3)

Application Number Title Priority Date Filing Date
ES541825A Expired ES8703828A1 (es) 1984-04-02 1985-04-01 Un procedimiento para producir acido 3-acetamido-4-trimetilaminabutirico h2o.
ES557180A Expired ES557180A1 (es) 1984-04-02 1986-11-03 Un procedimiento para producir aminocarnitina
ES557181A Expired ES8707709A1 (es) 1984-04-02 1986-11-03 Un procedimiento para producir derivados cristalinos de acido 3-acil o haloacil-amino-4-trimetilaminobutilico

Family Applications Before (2)

Application Number Title Priority Date Filing Date
ES541825A Expired ES8703828A1 (es) 1984-04-02 1985-04-01 Un procedimiento para producir acido 3-acetamido-4-trimetilaminabutirico h2o.
ES557180A Expired ES557180A1 (es) 1984-04-02 1986-11-03 Un procedimiento para producir aminocarnitina

Country Status (8)

Country Link
EP (1) EP0177574B1 (es)
JP (1) JPH0662523B2 (es)
KR (1) KR870001319B1 (es)
AU (1) AU570112B2 (es)
CA (1) CA1297901C (es)
DE (1) DE3574867D1 (es)
ES (3) ES8703828A1 (es)
WO (1) WO1985004396A1 (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1205758B (it) * 1987-03-18 1989-03-31 Sigma Tau Ind Farmaceuti Procedimento per la produzione di (-) n-acetil ammino carnitina e di (+) n-acetil ammino carnitina
IT1299266B1 (it) 1998-05-15 2000-02-29 Sigma Tau Ind Farmaceuti Inibitori reversibili della carnitina palmitoil trasferasi
JP6473352B2 (ja) * 2015-03-10 2019-02-20 利幸 糸井 虚血性疾患治療薬
KR102034429B1 (ko) 2017-11-30 2019-10-18 주식회사 포스코 강재 및 그 제조방법
CN114364385A (zh) 2019-08-30 2022-04-15 中国科学院动物研究所 用于对抗代谢疾病的组合物及其用途

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH370093A (fr) * 1956-07-17 1963-06-30 Roussel Uclaf Procédé pour la préparation de dérivés de l'acide diamino-caproïque
GB1093937A (en) * 1963-11-22 1967-12-06 Takeda Chemical Industries Ltd Betaines of lysine
FR1442318A (fr) * 1963-11-22 1966-06-17 Takeda Chemical Industries Ltd Procédé d'obtention de nouvelles bétaïnes de lysine
US4521432A (en) * 1981-11-26 1985-06-04 Takeda Chemical Industries, Ltd. Physiologically active substance FA-5859, its derivative, their production and use
DE3476656D1 (en) * 1983-05-25 1989-03-16 Takeda Chemical Industries Ltd Derivatives of beta-amino-gamma-trimethylammonio-butyrate, their production and use
JP2016000092A (ja) * 2014-06-11 2016-01-07 株式会社コスモ計器 指紋採取用シート

Also Published As

Publication number Publication date
DE3574867D1 (de) 1990-01-25
WO1985004396A1 (en) 1985-10-10
CA1297901C (en) 1992-03-24
ES557181A0 (es) 1987-08-16
ES541825A0 (es) 1987-03-01
AU4216685A (en) 1985-11-01
ES557180A1 (es) 1987-08-16
JPS61501776A (ja) 1986-08-21
AU570112B2 (en) 1988-03-03
EP0177574B1 (en) 1989-12-20
ES8703828A1 (es) 1987-03-01
KR870001319B1 (ko) 1987-07-13
EP0177574A1 (en) 1986-04-16
JPH0662523B2 (ja) 1994-08-17
KR860700032A (ko) 1986-01-31
EP0177574A4 (en) 1987-08-03

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Legal Events

Date Code Title Description
MM4A Patent lapsed

Effective date: 19960506