ES469821A1 - Un procedimiento para la preparacion de un derivado de ses- quiterpeno - Google Patents

Un procedimiento para la preparacion de un derivado de ses- quiterpeno

Info

Publication number
ES469821A1
ES469821A1 ES469821A ES469821A ES469821A1 ES 469821 A1 ES469821 A1 ES 469821A1 ES 469821 A ES469821 A ES 469821A ES 469821 A ES469821 A ES 469821A ES 469821 A1 ES469821 A1 ES 469821A1
Authority
ES
Spain
Prior art keywords
group
hydrogen atom
general formula
salts
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES469821A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Otsuka Pharmaceutical Co Ltd
Original Assignee
Otsuka Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP52078641A external-priority patent/JPS589114B2/ja
Priority claimed from JP15895977A external-priority patent/JPS5492680A/ja
Priority claimed from JP53014674A external-priority patent/JPS5936913B2/ja
Application filed by Otsuka Pharmaceutical Co Ltd filed Critical Otsuka Pharmaceutical Co Ltd
Publication of ES469821A1 publication Critical patent/ES469821A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/94—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom spiro-condensed with carbocyclic rings or ring systems, e.g. griseofulvins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/10—Spiro-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02—Oxygen as only ring hetero atoms
    • C12P17/04—Oxygen as only ring hetero atoms containing a five-membered hetero ring, e.g. griseofulvin, vitamin C

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Furan Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)

Abstract

Un procedimiento para la preparación de un derivado de sesquiterpeno, de fórmula (Ia): **(Fórmula)** que consiste en cultivar aeróbicamente un microorganismo del género Stachybotrys en un medio de cultivo que contiene fuentes asimilables de nitrógeno, carbono, sales inorgánicas y minerales traza, a un pH de 3,5 a 11,5 aproximadamente y a una temperatura de 15 a 35º C aproximadamente y recuperar el producto resultante de fórmula (Ia) del caldo de cultivo.
ES469821A 1977-06-30 1978-05-12 Un procedimiento para la preparacion de un derivado de ses- quiterpeno Expired ES469821A1 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP52078641A JPS589114B2 (ja) 1977-06-30 1977-06-30 セスキテルペン類縁体、その製造法及び腎炎治療剤
JP15895977A JPS5492680A (en) 1977-12-29 1977-12-29 Novel microorganism
JP53014674A JPS5936913B2 (ja) 1978-02-10 1978-02-10 セスキテルペン誘導体

Publications (1)

Publication Number Publication Date
ES469821A1 true ES469821A1 (es) 1979-09-16

Family

ID=27280728

Family Applications (2)

Application Number Title Priority Date Filing Date
ES469821A Expired ES469821A1 (es) 1977-06-30 1978-05-12 Un procedimiento para la preparacion de un derivado de ses- quiterpeno
ES477771A Expired ES477771A1 (es) 1977-06-30 1979-02-15 Un procedimiento para la preparacion de un derivado de ses- quiterpeno.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES477771A Expired ES477771A1 (es) 1977-06-30 1979-02-15 Un procedimiento para la preparacion de un derivado de ses- quiterpeno.

Country Status (17)

Country Link
US (1) US4229466A (es)
AR (1) AR228011A1 (es)
CA (1) CA1142106A (es)
CH (1) CH641452A5 (es)
DE (1) DE2821403C2 (es)
DK (2) DK154704C (es)
ES (2) ES469821A1 (es)
FR (1) FR2405941A1 (es)
GB (1) GB1601479A (es)
IE (1) IE46785B1 (es)
IT (1) IT1103138B (es)
MX (1) MX6053E (es)
NL (1) NL181804C (es)
NO (2) NO152220C (es)
NZ (1) NZ187243A (es)
PT (1) PT68035B (es)
SE (2) SE439322B (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5630917A (en) * 1979-08-22 1981-03-28 Otsuka Pharmaceut Co Ltd Preventive and remedy for hepatitis
US4423027A (en) * 1982-12-22 1983-12-27 Simon Lionel N Pharmaceutical compositions of deglycyrrhizinated licorice (DGL)
JPS6193179A (ja) * 1984-10-15 1986-05-12 Takara Shuzo Co Ltd グアニジルフンジン類の誘導体及びその製造方法
JPS646214A (en) * 1987-02-13 1989-01-10 Otsuka Pharma Co Ltd Remedy for ulcerative colonopathy
US5506247A (en) * 1988-04-15 1996-04-09 T Cell Sciences, Inc. Compounds that inhibit complement and/or suppress immune activity
US5173499A (en) * 1988-04-15 1992-12-22 T Cell Sciences, Inc. Compounds which inhibit complement and/or suppress immune activity
US5366986A (en) * 1988-04-15 1994-11-22 T Cell Sciences, Inc. Compounds which inhibit complement and/or suppress immune activity
US4981980A (en) * 1989-09-14 1991-01-01 Merck & Co., Inc. Drug for treating manic depression
EP0447813A1 (en) * 1990-02-28 1991-09-25 GRUPPO LEPETIT S.p.A. Water soluble salts of purpuromycin and pharmaceutical formulations thereof
US5532416A (en) * 1994-07-20 1996-07-02 Monsanto Company Benzoyl derivatives and synthesis thereof
DE69509643T2 (de) * 1994-03-25 1999-10-14 Gruppo Lepetit S.P.A. Sesquiterpenderivate
US5869688A (en) * 1994-07-20 1999-02-09 Monsanto Company Preparation of substituted 3-aryl-5-haloalkyl-pyrazoles having herbicidal activity
US5698708A (en) * 1996-06-20 1997-12-16 Monsanto Company Preparation of substituted 3-aryl-5-haloalkyl-pyrazoles having herbicidal activity
JP4194196B2 (ja) * 1999-02-22 2008-12-10 花王株式会社 浴用剤組成物

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3985896A (en) * 1975-07-15 1976-10-12 Smithkline Corporation Benzophenalenofurans
US4046805A (en) * 1976-05-10 1977-09-06 American Cyanamid Company Substituted-hydroxy-naphthalenedisulfonic acid compounds

Also Published As

Publication number Publication date
DK212778A (da) 1978-12-31
NO781704L (no) 1979-01-03
FR2405941A1 (fr) 1979-05-11
SE7805606L (sv) 1979-01-08
NL7805160A (nl) 1979-01-03
NL181804C (nl) 1987-11-02
NO834363L (no) 1979-01-03
CH641452A5 (de) 1984-02-29
SE8305390L (sv) 1983-09-30
MX6053E (es) 1984-10-16
DE2821403C2 (de) 1984-01-26
ES477771A1 (es) 1979-12-01
IE46785B1 (en) 1983-09-21
PT68035B (en) 1979-10-24
GB1601479A (en) 1981-10-28
CA1142106A (en) 1983-03-01
DE2821403A1 (de) 1979-01-25
IT1103138B (it) 1985-10-14
NL181804B (nl) 1987-06-01
SE452008B (sv) 1987-11-09
SE439322B (sv) 1985-06-10
NO152220B (no) 1985-05-13
NZ187243A (en) 1984-07-31
DK58487D0 (da) 1987-02-04
SE8305390D0 (sv) 1983-09-30
US4229466A (en) 1980-10-21
IT7849342A0 (it) 1978-05-15
DK154704C (da) 1989-05-08
IE780975L (en) 1978-12-30
DK154704B (da) 1988-12-12
AR228011A1 (es) 1983-01-14
DK155670B (da) 1989-05-01
DK155670C (da) 1989-09-18
PT68035A (en) 1978-05-31
DK58487A (da) 1987-02-04
NO154013C (no) 1986-07-02
NO152220C (no) 1985-08-21
NO154013B (no) 1986-03-24
FR2405941B1 (es) 1983-02-04

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20000301