ES471365A1 - Un procedimiento para la preparacion de derivados de 3-(4- bromofenil)-3-(3-piridil)-alilamina terapeuticamente activos - Google Patents
Un procedimiento para la preparacion de derivados de 3-(4- bromofenil)-3-(3-piridil)-alilamina terapeuticamente activosInfo
- Publication number
- ES471365A1 ES471365A1 ES471365A ES471365A ES471365A1 ES 471365 A1 ES471365 A1 ES 471365A1 ES 471365 A ES471365 A ES 471365A ES 471365 A ES471365 A ES 471365A ES 471365 A1 ES471365 A1 ES 471365A1
- Authority
- ES
- Spain
- Prior art keywords
- preparation
- therapeutically active
- pyridine compounds
- novel intermediate
- active pyridine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title abstract 2
- 150000003222 pyridines Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 6
- 239000000935 antidepressant agent Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
- C07D213/30—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/26—Radicals substituted by halogen atoms or nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
- C07D213/38—Radicals substituted by singly-bound nitrogen atoms having only hydrogen or hydrocarbon radicals attached to the substituent nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F3/00—Compounds containing elements of Groups 2 or 12 of the Periodic Table
- C07F3/02—Magnesium compounds
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pyridine Compounds (AREA)
Abstract
Un procedimiento para la preparación de derivados de 3-(4-bromofenil)-3-(3-piridil)-alilamina terapéuticamente activos de la fórmula: **(Fórmula)** en la que R es metilo o hidrógeno, un isómero geométrico de dichos compuestos o una sal terapéuticamente aceptable de dichos compuestos o isómeros geométricos en cualquier grado de hidratación.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE7707708A SE409860B (sv) | 1977-07-04 | 1977-07-04 | En ny mellanprodukt for framstellning av terapeutiskt aktiva pyridinforeningar |
Publications (1)
Publication Number | Publication Date |
---|---|
ES471365A1 true ES471365A1 (es) | 1979-10-01 |
Family
ID=20331765
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES471365A Expired ES471365A1 (es) | 1977-07-04 | 1978-07-03 | Un procedimiento para la preparacion de derivados de 3-(4- bromofenil)-3-(3-piridil)-alilamina terapeuticamente activos |
Country Status (20)
Country | Link |
---|---|
US (1) | US4216328A (es) |
EP (1) | EP0006864B1 (es) |
JP (2) | JPS607981B2 (es) |
AT (1) | AT364825B (es) |
AU (1) | AU520374B2 (es) |
BE (1) | BE868701A (es) |
CA (1) | CA1099725A (es) |
CH (1) | CH642354A5 (es) |
DK (1) | DK295278A (es) |
ES (1) | ES471365A1 (es) |
FI (1) | FI64579C (es) |
GB (1) | GB2036002B (es) |
IE (1) | IE47017B1 (es) |
IL (1) | IL54973A (es) |
IT (1) | IT1105249B (es) |
NL (1) | NL7807121A (es) |
NO (1) | NO150604C (es) |
SE (1) | SE409860B (es) |
SU (1) | SU927113A3 (es) |
WO (1) | WO1979000024A1 (es) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE7909514L (sv) | 1979-11-16 | 1981-05-17 | Astra Laekemedel Ab | Nya halofenyl-pyridyl-allylaminderivat |
JPH0354870Y2 (es) * | 1985-10-28 | 1991-12-04 | ||
DE4036216C1 (es) * | 1990-11-14 | 1992-01-30 | Voest-Alpine Industrieanlagenbau Ges.M.B.H., Linz, At |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB850298A (en) * | 1956-10-30 | 1960-10-05 | Maggioni & C Societa Per Azion | ª‡,ª‡[(p-chlorophenyl)-(4-pyridyl)] carbinols and method of preparing same |
DE1468359A1 (de) * | 1963-10-23 | 1968-11-28 | Merck & Co Inc | Verfahren zur Herstellung von Dibenzocycloheptehderivaten |
US3396224A (en) * | 1965-09-09 | 1968-08-06 | Lilly Co Eli | Controlling phytopathogenic fungi on plants with 3-pyridyl methane derivatives |
US3471505A (en) * | 1967-02-01 | 1969-10-07 | Ciba Geigy Corp | 1-(alkoxyphenyl)-1-(3-pyridyl)-carbinols |
US3928369A (en) * | 1971-04-28 | 1975-12-23 | Haessle Ab | Compounds useful as antidepressive agents, and a process for their preparation |
US4094908A (en) * | 1973-08-15 | 1978-06-13 | Richter Gedeon Vegyeszeti Gyar Rt. | Alpha-substituted benzhydrol derivatives |
GB1480593A (en) * | 1973-11-30 | 1977-07-20 | Kefalas As | Xanthene and thioxanthene derivatives having pharmaceutical activity |
SE388854B (sv) * | 1974-11-21 | 1979-03-26 | Astra Laekemedel Ab | Forfarande for framstellning av fenylpyridylaminderivat |
-
1977
- 1977-07-04 SE SE7707708A patent/SE409860B/sv unknown
-
1978
- 1978-06-22 IL IL54973A patent/IL54973A/xx unknown
- 1978-06-26 US US05/918,724 patent/US4216328A/en not_active Expired - Lifetime
- 1978-06-26 CH CH330079A patent/CH642354A5/de not_active IP Right Cessation
- 1978-06-26 EP EP78900032A patent/EP0006864B1/en not_active Expired
- 1978-06-26 WO PCT/SE1978/000010 patent/WO1979000024A1/en unknown
- 1978-06-26 GB GB7920315A patent/GB2036002B/en not_active Expired
- 1978-06-29 DK DK782952A patent/DK295278A/da not_active Application Discontinuation
- 1978-06-29 AU AU37613/78A patent/AU520374B2/en not_active Expired
- 1978-06-30 CA CA306,599A patent/CA1099725A/en not_active Expired
- 1978-06-30 NL NL7807121A patent/NL7807121A/xx not_active Application Discontinuation
- 1978-06-30 FI FI782116A patent/FI64579C/fi not_active IP Right Cessation
- 1978-07-03 IE IE1334/78A patent/IE47017B1/en unknown
- 1978-07-03 IT IT50141/78A patent/IT1105249B/it active
- 1978-07-03 ES ES471365A patent/ES471365A1/es not_active Expired
- 1978-07-03 NO NO782303A patent/NO150604C/no unknown
- 1978-07-04 JP JP53081819A patent/JPS607981B2/ja not_active Expired
- 1978-07-04 AT AT0483678A patent/AT364825B/de not_active IP Right Cessation
- 1978-07-04 BE BE189041A patent/BE868701A/xx not_active IP Right Cessation
-
1979
- 1979-08-03 SU SU792800303A patent/SU927113A3/ru active
-
1982
- 1982-04-22 JP JP57066429A patent/JPS609024B2/ja not_active Expired
Also Published As
Publication number | Publication date |
---|---|
BE868701A (fr) | 1979-01-04 |
WO1979000024A1 (en) | 1979-01-25 |
NO150604C (no) | 1984-11-14 |
IE47017B1 (en) | 1983-11-30 |
IE781334L (en) | 1979-01-04 |
NO150604B (no) | 1984-08-06 |
NO782303L (no) | 1979-01-05 |
EP0006864B1 (en) | 1981-12-30 |
DK295278A (da) | 1979-01-05 |
EP0006864A1 (en) | 1980-01-23 |
SE7707708L (sv) | 1979-01-05 |
FI782116A (fi) | 1979-01-05 |
AU3761378A (en) | 1980-01-03 |
FI64579B (fi) | 1983-08-31 |
CA1099725A (en) | 1981-04-21 |
JPS609024B2 (ja) | 1985-03-07 |
IT7850141A0 (it) | 1978-07-03 |
SU927113A3 (ru) | 1982-05-07 |
JPS57183759A (en) | 1982-11-12 |
CH642354A5 (de) | 1984-04-13 |
JPS5414975A (en) | 1979-02-03 |
NL7807121A (nl) | 1979-01-08 |
JPS607981B2 (ja) | 1985-02-28 |
SE409860B (sv) | 1979-09-10 |
IT1105249B (it) | 1985-10-28 |
IL54973A0 (en) | 1978-08-31 |
ATA483678A (de) | 1981-04-15 |
GB2036002A (en) | 1980-06-25 |
AU520374B2 (en) | 1982-01-28 |
AT364825B (de) | 1981-11-25 |
IL54973A (en) | 1981-12-31 |
FI64579C (fi) | 1983-12-12 |
GB2036002B (en) | 1982-04-21 |
US4216328A (en) | 1980-08-05 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD1A | Patent lapsed |
Effective date: 20000601 |