ES385557A1 - 06-methyl-steroids and processes for their preparation - Google Patents
06-methyl-steroids and processes for their preparationInfo
- Publication number
- ES385557A1 ES385557A1 ES385557A ES385557A ES385557A1 ES 385557 A1 ES385557 A1 ES 385557A1 ES 385557 A ES385557 A ES 385557A ES 385557 A ES385557 A ES 385557A ES 385557 A1 ES385557 A1 ES 385557A1
- Authority
- ES
- Spain
- Prior art keywords
- steroids
- methyl
- general formula
- formula
- hydroxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Steroid Compounds (AREA)
Abstract
Procedure for the preparation of 16-nethyl steroids of the general formula I **(See formula)** in which RO means an esterified or etherified hydroxy group and R1 means F, Cl, Br, CH3 or CF3 and where an additional double bond may optionally be present in position 6 (7), characterized in that a 3-hydroxy-l6-methyl-steroid of the general formula II **(See formula)** in which R1 has the indicated significance and where an additional double bond may eventually be present in position 6 (7), or a 3-position esterified derivative suitable for reaction of one of such 3-hydroxy-16-methyl-steroids is treated with an esterifying or etherifying agent of the general formula ROH in which R has the indicated significance, or with a derivative suitable for the reaction of one of such compounds or because in a steroid that otherwise corresponds to formula I, a functionally altered 20-preserve group is solvolitically released. (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19691957473 DE1957473A1 (en) | 1969-11-15 | 1969-11-15 | 16-methyl steroids and process for their preparation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES385557A1 true ES385557A1 (en) | 1973-03-16 |
Family
ID=5751167
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES385557A Expired ES385557A1 (en) | 1969-11-15 | 1970-11-14 | 06-methyl-steroids and processes for their preparation |
Country Status (17)
| Country | Link |
|---|---|
| JP (1) | JPS501271B1 (en) |
| AT (2) | AT313489B (en) |
| BE (1) | BE758843A (en) |
| BR (1) | BR6915400D0 (en) |
| CH (1) | CH549561A (en) |
| CS (1) | CS156510B2 (en) |
| DE (1) | DE1957473A1 (en) |
| DK (1) | DK131608C (en) |
| ES (1) | ES385557A1 (en) |
| FR (1) | FR2073362B1 (en) |
| GB (1) | GB1282520A (en) |
| HU (1) | HU162451B (en) |
| IL (1) | IL35432A (en) |
| NL (1) | NL7013989A (en) |
| PL (1) | PL81132B1 (en) |
| SE (2) | SE378826B (en) |
| ZA (1) | ZA706463B (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS54114684U (en) * | 1978-01-28 | 1979-08-11 | ||
| JPH0389670U (en) * | 1989-12-29 | 1991-09-12 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1094258B (en) * | 1959-02-17 | 1960-12-08 | Merck Ag E | Process for the preparation of fluorinated 16-methyl steroids |
-
0
- BE BE758843D patent/BE758843A/en unknown
-
1969
- 1969-11-15 DE DE19691957473 patent/DE1957473A1/en active Pending
- 1969-12-19 BR BR215400/69A patent/BR6915400D0/en unknown
-
1970
- 1970-08-10 CH CH1198370A patent/CH549561A/en not_active IP Right Cessation
- 1970-09-22 ZA ZA706463A patent/ZA706463B/en unknown
- 1970-09-22 GB GB45060/70A patent/GB1282520A/en not_active Expired
- 1970-09-22 NL NL7013989A patent/NL7013989A/xx unknown
- 1970-10-08 DK DK511070A patent/DK131608C/en active
- 1970-10-12 IL IL35432A patent/IL35432A/en unknown
- 1970-10-23 CS CS717470A patent/CS156510B2/cs unknown
- 1970-11-02 PL PL1970144208A patent/PL81132B1/pl unknown
- 1970-11-10 SE SE7305984A patent/SE378826B/xx unknown
- 1970-11-10 SE SE15151/70A patent/SE364707B/xx unknown
- 1970-11-13 HU HUME1288A patent/HU162451B/hu unknown
- 1970-11-13 FR FR7040683A patent/FR2073362B1/fr not_active Expired
- 1970-11-13 AT AT1025270A patent/AT313489B/en not_active IP Right Cessation
- 1970-11-13 AT AT931072*1A patent/AT324587B/en not_active IP Right Cessation
- 1970-11-14 JP JP45099881A patent/JPS501271B1/ja active Pending
- 1970-11-14 ES ES385557A patent/ES385557A1/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| BE758843A (en) | 1971-05-12 |
| SE378826B (en) | 1975-09-15 |
| IL35432A0 (en) | 1971-04-28 |
| CH549561A (en) | 1974-05-31 |
| DK131608B (en) | 1975-08-11 |
| ZA706463B (en) | 1971-05-27 |
| PL81132B1 (en) | 1975-08-30 |
| IL35432A (en) | 1974-11-29 |
| FR2073362B1 (en) | 1974-09-27 |
| HU162451B (en) | 1973-02-28 |
| CS156510B2 (en) | 1974-07-24 |
| DE1957473A1 (en) | 1971-05-27 |
| AT313489B (en) | 1974-02-25 |
| JPS501271B1 (en) | 1975-01-16 |
| NL7013989A (en) | 1971-05-18 |
| SE364707B (en) | 1974-03-04 |
| BR6915400D0 (en) | 1973-03-13 |
| FR2073362A1 (en) | 1971-10-01 |
| DK131608C (en) | 1976-01-19 |
| AT324587B (en) | 1975-09-10 |
| GB1282520A (en) | 1972-07-19 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES300814A1 (en) | A procedure for the preparation of steroid compounds (Machine-translation by Google Translate, not legally binding) | |
| ES385557A1 (en) | 06-methyl-steroids and processes for their preparation | |
| ES295331A1 (en) | 3-hydroxy-1, 5-bis-dehydro steroids and methods for their manufacture | |
| ES412235A1 (en) | Anti-inflammatory pregnane derivative | |
| ES390459A1 (en) | Oestrone derivative and a process for its manufacture | |
| ES334055A1 (en) | Procedure for the preparation of useful products for radiodiagnosis. (Machine-translation by Google Translate, not legally binding) | |
| ES276465A1 (en) | Procedure for preparing derivatives of 19-nor-testosterone (Machine-translation by Google Translate, not legally binding) | |
| ES333171A1 (en) | Procedure for the preparation of new esters 21 delta 16 alfametilesteroides. (Machine-translation by Google Translate, not legally binding) | |
| ES432262A1 (en) | Procedure for obtaining eteres and esters of 3, 3- difenol-2-indolinone. (Machine-translation by Google Translate, not legally binding) | |
| ES319114A1 (en) | A procedure for preparing the 21-hydroxy steroids of the pregnan series esterified in the position 21. (Machine-translation by Google Translate, not legally binding) | |
| ES358836A1 (en) | Procedure for the obtaining of organic acid esters of 3-beta-hydroxy-5-androsten-17-ona (dehidroepian-drosterone) with 3 to 14 atomos c in the rest of ester. (Machine-translation by Google Translate, not legally binding) | |
| ES330941A1 (en) | Procedure for the manufacture of 5 beta-h-6 cetoesteroides-2 beta, 3 beta-disustitute. (Machine-translation by Google Translate, not legally binding) | |
| ES320392A3 (en) | Procedure for the obtaining of hormonal derivatives. (Machine-translation by Google Translate, not legally binding) | |
| ES388783A1 (en) | Pregna-4,9-diene processes for its preparation and compositions thereof | |
| ES410933A1 (en) | 15alpha,16alpha-methylene-delta4-oestren-17beta-ols | |
| ES344654A1 (en) | Process for preparing 3-indolyl acetic acids | |
| ES399242A1 (en) | Procedure to prepare delta-6-esteroides of the strange series. (Machine-translation by Google Translate, not legally binding) | |
| ES386351A1 (en) | Terpenic homoterpenic and terpenylacetic acid esters of 19-nortes terone | |
| ES371696A1 (en) | Procedure for the preparation of cortico-steroid esters. (Machine-translation by Google Translate, not legally binding) | |
| ES219424A1 (en) | Procedure for obtaining steroid derivatives of 6-alcoxy-tropine (Machine-translation by Google Translate, not legally binding) | |
| ES392567A1 (en) | Procedure for the preparation of 18-methyl-17-alpha-etiniltestosteron-esteres. (Machine-translation by Google Translate, not legally binding) | |
| ES264430A1 (en) | A procedure of preparation derivatives of pre-non-bishidroximethylene (Machine-translation by Google Translate, not legally binding) | |
| ES415478A1 (en) | Procedure for the preparation of esters of the antibiotic g7-694 (rosamicina). (Machine-translation by Google Translate, not legally binding) | |
| ES320497A1 (en) | Procedure for the obtaining of dexamethasone 21-pivalate. (Machine-translation by Google Translate, not legally binding) | |
| ES390641A1 (en) | Cardio-active glycosides of 3beta,14-dihydroxy - 4,5beta - oxido - 14beta - bufa - 20,22-dienolides and process for their preparation |