ES388783A1 - Pregna-4,9-diene processes for its preparation and compositions thereof - Google Patents

Pregna-4,9-diene processes for its preparation and compositions thereof

Info

Publication number
ES388783A1
ES388783A1 ES388783A ES388783A ES388783A1 ES 388783 A1 ES388783 A1 ES 388783A1 ES 388783 A ES388783 A ES 388783A ES 388783 A ES388783 A ES 388783A ES 388783 A1 ES388783 A1 ES 388783A1
Authority
ES
Spain
Prior art keywords
pregna
diene
formula
13beta
17alpha
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES388783A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Roussel Uclaf SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf SA filed Critical Roussel Uclaf SA
Publication of ES388783A1 publication Critical patent/ES388783A1/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J3/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Preparation procedure for 3,20-dioxo-13beta-ethyl-17alpha-methyl-18,19-dinor-pregna-4,9-diene of formula I **(See formula)** characterized in that the alcohol function in position 20 of the 3-oxo-13beta-ethyl-17alpha-methyl-20alpha-hydroxy-18,19-dinor-pregna-4,9-diene of formula IIA is oxidized **(See formula)** or of 3-oxo-13beta-ethyl-17alpha-methyl-20beta-hydroxy-18,19-dinor-pregna-4,9-diene of formula IIB **(See formula)** or of a mixture of these two compounds, by means of an oxidizing agent, such as chromic anhydride, in the presence of sulfuric acid, in acetone medium, and the desired compound is isolated. (Machine-translation by Google Translate, not legally binding)
ES388783A 1970-03-03 1971-03-02 Pregna-4,9-diene processes for its preparation and compositions thereof Expired ES388783A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR707007551A FR2081561B1 (en) 1970-03-03 1970-03-03

Publications (1)

Publication Number Publication Date
ES388783A1 true ES388783A1 (en) 1974-02-16

Family

ID=9051572

Family Applications (1)

Application Number Title Priority Date Filing Date
ES388783A Expired ES388783A1 (en) 1970-03-03 1971-03-02 Pregna-4,9-diene processes for its preparation and compositions thereof

Country Status (14)

Country Link
JP (1) JPS5343497B1 (en)
AT (1) AT307636B (en)
BE (1) BE763660A (en)
CA (1) CA934367A (en)
CH (1) CH536829A (en)
DE (1) DE2109853B2 (en)
DK (1) DK124127B (en)
ES (1) ES388783A1 (en)
FR (1) FR2081561B1 (en)
GB (1) GB1323383A (en)
IL (1) IL36214A (en)
NL (1) NL169592C (en)
SE (1) SE368397B (en)
ZA (1) ZA711131B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1173408B (en) * 1984-02-29 1987-06-24 Hudson Italiana Spa VENTILATOR, OF THE CAVE Bladed Type, WITH THE INSIDE OF EACH VACUUM VACUUM
DE102007027636A1 (en) * 2007-06-12 2008-12-18 Bayer Schering Pharma Aktiengesellschaft 17β-Cyano-18α-homo-19-nor-androst-4-ene derivative, its use and the derivative-containing drug

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1487510A (en) * 1965-06-01 1967-07-07 Merck & Co Inc Process for the production of gonenols and substituted gonadienols

Also Published As

Publication number Publication date
SE368397B (en) 1974-07-01
GB1323383A (en) 1973-07-11
IL36214A0 (en) 1971-04-28
JPS5343497B1 (en) 1978-11-20
DE2109853A1 (en) 1971-09-23
NL7102735A (en) 1971-09-07
BE763660A (en) 1971-09-02
FR2081561A1 (en) 1971-12-10
DE2109853C3 (en) 1980-02-21
CA934367A (en) 1973-09-25
FR2081561B1 (en) 1973-04-06
IL36214A (en) 1974-09-10
DE2109853B2 (en) 1979-06-21
CH536829A (en) 1973-05-15
ZA711131B (en) 1972-03-29
NL169592C (en) 1982-08-02
AT307636B (en) 1973-05-25
DK124127B (en) 1972-09-18

Similar Documents

Publication Publication Date Title
ES388783A1 (en) Pregna-4,9-diene processes for its preparation and compositions thereof
ES290968A1 (en) Procedure for preparing a diol and its derivatives (Machine-translation by Google Translate, not legally binding)
ES429020A1 (en) Certain 2-alkyl-5-oxymethylthiazoles
ES374039A1 (en) Procedure for the preparation of new 1,3,4-tadiazoles. (Machine-translation by Google Translate, not legally binding)
ES360810A1 (en) A method for the preparation of ketones. (Machine-translation by Google Translate, not legally binding)
ES392355A1 (en) D-homosteroid imides and a process for the preparation thereof
ES394504A1 (en) Cycloalkyl(f)(l)benzopyrans
ES400056A1 (en) 15alpha,16alpha-methylene steroids and processes for their production and use
ES390243A1 (en) Phenanthrotriazolyl derivatives
ES406542A1 (en) Derivatives of 22-fluoro-digoxins
ES384331A1 (en) Procedure for the obtaining of 6 alpha-methyl-19-nor-progesterone. (Machine-translation by Google Translate, not legally binding)
ES449938A1 (en) Preparation of gamma-pyrones
GB1238934A (en)
ES389292A1 (en) Process for the manufacture of optically active bicycloalkane derivatives
GB1054632A (en)
ES385557A1 (en) 06-methyl-steroids and processes for their preparation
ES422248A1 (en) Procedure for the preparation of 7-chlorine-1,2-dihydro-5-phenyl - 1,4-benzodiazepin-2-onas. (Machine-translation by Google Translate, not legally binding)
ES451289A1 (en) Procedure for the preparation of benzofuran derivatives. (Machine-translation by Google Translate, not legally binding)
ES384155A1 (en) An analogical procedure for the preparation of new steroid compounds. (Machine-translation by Google Translate, not legally binding)
GB1077037A (en) Improvements in or relating to novel steroids and the manufacture thereof
ES296880A1 (en) Procedure for obtaining steroid compounds (Machine-translation by Google Translate, not legally binding)
ES351328A1 (en) Procedure for the preparation of proscilaridine a derivatives (Machine-translation by Google Translate, not legally binding)
GB942613A (en) Structural material compositions containing clay
ES283961A1 (en) Procedure for the preparation of d-nor-steroids (Machine-translation by Google Translate, not legally binding)
ES361095A3 (en) A procedure for the preparation of delta 1,4 - pregnadiene - ii/3, 16 alpha 17 alpha, 21 - tetrahydroxy - 3,20 - diona, 16,17 - acetonido. (Machine-translation by Google Translate, not legally binding)