ES330941A1 - Procedure for the manufacture of 5 beta-h-6 cetoesteroides-2 beta, 3 beta-disustitute. (Machine-translation by Google Translate, not legally binding) - Google Patents
Procedure for the manufacture of 5 beta-h-6 cetoesteroides-2 beta, 3 beta-disustitute. (Machine-translation by Google Translate, not legally binding)Info
- Publication number
- ES330941A1 ES330941A1 ES0330941A ES330941A ES330941A1 ES 330941 A1 ES330941 A1 ES 330941A1 ES 0330941 A ES0330941 A ES 0330941A ES 330941 A ES330941 A ES 330941A ES 330941 A1 ES330941 A1 ES 330941A1
- Authority
- ES
- Spain
- Prior art keywords
- beta
- manufacture
- disustitute
- cetoesteroides
- translation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J75/00—Processes for the preparation of steroids in general
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Process for the manufacture of 5 β -H-6-ketosteroids 2 β, 3 β -disubstituted partial formula ** (See formula) ** wherein R1 and R2 signify hydrogen or an acyl residue, characterized in that 5 α -H-3,6-diketoesteroids of the partial formula are selectively brominated ** (See formula) ** in position 2 α, the 3-keto group of the 2 α The resultant is selectively reduced, and the bromine atom 2 α of the compound 2 α -bromo-3 β -hydroxy-6-keto-5 α -H obtained, if desired after the previous esterification of the hydroxyl group 3 β by known methods, it is then replaced by simultaneous isomerization of the hydrogen atom 5 α to the state of the hydrogen atom 5 β by the acyloxy group 2 β and then, if desired, the existing hydroxy groups are esterified as usual or the acyloxy groups are saponified, and if desired, the resulting hydroxyl groups are re-esterified.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DESC037892 | 1965-10-15 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES330941A1 true ES330941A1 (en) | 1967-12-01 |
Family
ID=7434487
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES0330941A Expired ES330941A1 (en) | 1965-10-15 | 1966-09-06 | Procedure for the manufacture of 5 beta-h-6 cetoesteroides-2 beta, 3 beta-disustitute. (Machine-translation by Google Translate, not legally binding) |
Country Status (12)
| Country | Link |
|---|---|
| BE (1) | BE686153A (en) |
| BR (1) | BR6683599D0 (en) |
| CH (1) | CH475221A (en) |
| DE (1) | DE1493175C3 (en) |
| DK (1) | DK114772B (en) |
| ES (1) | ES330941A1 (en) |
| FI (1) | FI43073B (en) |
| FR (1) | FR1502943A (en) |
| GB (1) | GB1157252A (en) |
| IL (1) | IL26226A (en) |
| NL (1) | NL6614542A (en) |
| SE (1) | SE330533B (en) |
-
1965
- 1965-10-15 DE DE19651493175 patent/DE1493175C3/en not_active Expired
-
1966
- 1966-07-26 IL IL2622666A patent/IL26226A/en unknown
- 1966-08-23 FI FI218966A patent/FI43073B/fi active
- 1966-08-30 BE BE686153D patent/BE686153A/xx unknown
- 1966-09-06 ES ES0330941A patent/ES330941A1/en not_active Expired
- 1966-09-27 DK DK500766A patent/DK114772B/en unknown
- 1966-09-29 CH CH1407566A patent/CH475221A/en not_active IP Right Cessation
- 1966-10-03 GB GB4404866A patent/GB1157252A/en not_active Expired
- 1966-10-12 BR BR18359966A patent/BR6683599D0/en unknown
- 1966-10-14 SE SE1399366A patent/SE330533B/xx unknown
- 1966-10-14 FR FR80054A patent/FR1502943A/en not_active Expired
- 1966-10-14 NL NL6614542A patent/NL6614542A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CH475221A (en) | 1969-07-15 |
| GB1157252A (en) | 1969-07-02 |
| DK114772B (en) | 1969-08-04 |
| DE1493175A1 (en) | 1969-06-26 |
| BR6683599D0 (en) | 1973-12-18 |
| FR1502943A (en) | 1967-11-24 |
| FI43073B (en) | 1970-10-01 |
| NL6614542A (en) | 1967-04-17 |
| SE330533B (en) | 1970-11-23 |
| BE686153A (en) | 1967-02-28 |
| DE1493175C3 (en) | 1974-03-14 |
| IL26226A (en) | 1972-04-27 |
| DE1493175B2 (en) | 1973-08-02 |
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