ES264430A1 - A procedure of preparation derivatives of pre-non-bishidroximethylene (Machine-translation by Google Translate, not legally binding) - Google Patents

A procedure of preparation derivatives of pre-non-bishidroximethylene (Machine-translation by Google Translate, not legally binding)

Info

Publication number
ES264430A1
ES264430A1 ES0264430A ES264430A ES264430A1 ES 264430 A1 ES264430 A1 ES 264430A1 ES 0264430 A ES0264430 A ES 0264430A ES 264430 A ES264430 A ES 264430A ES 264430 A1 ES264430 A1 ES 264430A1
Authority
ES
Spain
Prior art keywords
translation
machine
legally binding
*** translate
bishidroximethylene
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES0264430A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratoires Francais de Chimiotherapie SA
Laboratoires Francaise de Chimiotherapie
Original Assignee
Laboratoires Francais de Chimiotherapie SA
Laboratoires Francaise de Chimiotherapie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratoires Francais de Chimiotherapie SA, Laboratoires Francaise de Chimiotherapie filed Critical Laboratoires Francais de Chimiotherapie SA
Publication of ES264430A1 publication Critical patent/ES264430A1/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J9/00Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J41/00Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J41/00Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0055Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of at least three carbon atoms which may or may not be branched, e.g. cholane or cholestane derivatives, optionally cyclised, e.g. 17-beta-phenyl or 17-beta-furyl derivatives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J75/00Processes for the preparation of steroids in general

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)

Abstract

A process for the preparation of the compounds of the general formula: ** (See formula) ** wherein R1 represents H2, O or (see formula), and R2 and R3 represent H or an acyl radical, characterized mainly by introducing bromine at positions 2 and 4 of a 3-keto 20,20-bis-hydroxymethylene steroid whose hydroxyls in 20 have been previously blocked by an acyl radical, the brominated compound is de-brominated and the primary hydroxyl groups of the 3-keto-20,20-bis-acyloxymethylene Δ 1,4-steroid obtained are liberated by saponification, optionally in organic or mineral diester, such as dinitrate. (Machine-translation by Google Translate, not legally binding)
ES0264430A 1960-07-05 1961-01-28 A procedure of preparation derivatives of pre-non-bishidroximethylene (Machine-translation by Google Translate, not legally binding) Expired ES264430A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR832083A FR1365256A (en) 1960-07-05 1960-07-05 Bis-hydroxymethylene pregnane derivatives and method of manufacture

Publications (1)

Publication Number Publication Date
ES264430A1 true ES264430A1 (en) 1961-08-16

Family

ID=8734891

Family Applications (1)

Application Number Title Priority Date Filing Date
ES0264430A Expired ES264430A1 (en) 1960-07-05 1961-01-28 A procedure of preparation derivatives of pre-non-bishidroximethylene (Machine-translation by Google Translate, not legally binding)

Country Status (4)

Country Link
CH (1) CH394192A (en)
ES (1) ES264430A1 (en)
FR (2) FR1365256A (en)
NL (2) NL261312A (en)

Also Published As

Publication number Publication date
FR695M (en) 1961-07-24
NL261312A (en) 1964-01-01
NL108128C (en) 1964-03-17
CH394192A (en) 1965-06-30
FR1365256A (en) 1964-07-03

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