ES2195027T3 - Nuevos derivados de purina que poseen en particular propiedades anti-proliferativas y sus aplicaciones biologicas. - Google Patents

Nuevos derivados de purina que poseen en particular propiedades anti-proliferativas y sus aplicaciones biologicas.

Info

Publication number
ES2195027T3
ES2195027T3 ES96941088T ES96941088T ES2195027T3 ES 2195027 T3 ES2195027 T3 ES 2195027T3 ES 96941088 T ES96941088 T ES 96941088T ES 96941088 T ES96941088 T ES 96941088T ES 2195027 T3 ES2195027 T3 ES 2195027T3
Authority
ES
Spain
Prior art keywords
purine derivatives
rnh
cyclin
alkyl
biological applications
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES96941088T
Other languages
English (en)
Inventor
Laurent Meijer
Emile Bisagni
Michel Legraverend
Miroslav Strnad
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
INST BOTAN EXPERIMENTALE
Centre National de la Recherche Scientifique CNRS
Original Assignee
INST BOTAN EXPERIMENTALE
Centre National de la Recherche Scientifique CNRS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by INST BOTAN EXPERIMENTALE, Centre National de la Recherche Scientifique CNRS filed Critical INST BOTAN EXPERIMENTALE
Application granted granted Critical
Publication of ES2195027T3 publication Critical patent/ES2195027T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/16—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Abstract

LA INVENCION SE REFIERE A DERIVADOS DE LA PURINA SUSTITUIDOS EN LAS POSICIONES 2, 6 Y 9. SE TRATA EN PARTICULAR DE LA 2 - (1 R HIDROXIMETILPROPILAMINO) - 6 - BENCILAMINO - 9 ISOPROPILPURINA. ESTOS DERIVADOS PRESENTAN EN PARTICULAR PROPIEDADES ANTIPROLIFERATIVAS Y PUEDEN UTILIZARSE COMO MEDICAMENTOS Y COMO HERBICIDAS.
ES96941088T 1995-12-01 1996-11-29 Nuevos derivados de purina que poseen en particular propiedades anti-proliferativas y sus aplicaciones biologicas. Expired - Lifetime ES2195027T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9514237A FR2741881B1 (fr) 1995-12-01 1995-12-01 Nouveaux derives de purine possedant notamment des prorietes anti-proliferatives et leurs applications biologiques

Publications (1)

Publication Number Publication Date
ES2195027T3 true ES2195027T3 (es) 2003-12-01

Family

ID=9485066

Family Applications (2)

Application Number Title Priority Date Filing Date
ES02293256T Expired - Lifetime ES2364722T3 (es) 1995-12-01 1996-11-29 Derivado de purina para usar en el tratamiento de un trastorno proliferativo.
ES96941088T Expired - Lifetime ES2195027T3 (es) 1995-12-01 1996-11-29 Nuevos derivados de purina que poseen en particular propiedades anti-proliferativas y sus aplicaciones biologicas.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES02293256T Expired - Lifetime ES2364722T3 (es) 1995-12-01 1996-11-29 Derivado de purina para usar en el tratamiento de un trastorno proliferativo.

Country Status (11)

Country Link
US (6) US6316456B1 (es)
EP (2) EP0874847B1 (es)
JP (1) JP4340796B2 (es)
AT (2) ATE500255T1 (es)
CA (1) CA2238843C (es)
DE (2) DE69626855T2 (es)
DK (2) DK0874847T3 (es)
ES (2) ES2364722T3 (es)
FR (1) FR2741881B1 (es)
PT (2) PT1308447E (es)
WO (1) WO1997020842A1 (es)

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PT874847E (pt) 2003-08-29
DE69638337D1 (de) 2011-04-14
DK1308447T3 (da) 2011-06-20
EP1308447B1 (fr) 2011-03-02
ES2364722T3 (es) 2011-09-13
CA2238843C (fr) 2012-04-10
PT1308447E (pt) 2011-06-07
CA2238843A1 (fr) 1997-06-12
FR2741881A1 (fr) 1997-06-06
EP0874847A1 (fr) 1998-11-04
JP2000501408A (ja) 2000-02-08
DE69626855T2 (de) 2003-12-24
ATE234838T1 (de) 2003-04-15
EP0874847B1 (fr) 2003-03-19
EP1308447A1 (fr) 2003-05-07
FR2741881B1 (fr) 1999-07-30
US20100273802A1 (en) 2010-10-28
DK0874847T3 (da) 2003-07-14
US20020049218A1 (en) 2002-04-25
ATE500255T1 (de) 2011-03-15
WO1997020842A1 (fr) 1997-06-12
DE69626855D1 (de) 2003-04-24
JP4340796B2 (ja) 2009-10-07
US20030186999A1 (en) 2003-10-02
US20040235868A1 (en) 2004-11-25
US20090030019A1 (en) 2009-01-29
US6316456B1 (en) 2001-11-13
US8163762B2 (en) 2012-04-24

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