ES2145997T3 - Composiciones de aminoacidos y uso de las mismas en la nutricion clinica. - Google Patents
Composiciones de aminoacidos y uso de las mismas en la nutricion clinica.Info
- Publication number
- ES2145997T3 ES2145997T3 ES96904849T ES96904849T ES2145997T3 ES 2145997 T3 ES2145997 T3 ES 2145997T3 ES 96904849 T ES96904849 T ES 96904849T ES 96904849 T ES96904849 T ES 96904849T ES 2145997 T3 ES2145997 T3 ES 2145997T3
- Authority
- ES
- Spain
- Prior art keywords
- tnf
- amino acid
- levels
- same
- acid compositions
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 150000001413 amino acids Chemical class 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title abstract 2
- 235000016709 nutrition Nutrition 0.000 title abstract 2
- 230000035764 nutrition Effects 0.000 title 1
- 108060008682 Tumor Necrosis Factor Proteins 0.000 abstract 5
- 102000003390 tumor necrosis factor Human genes 0.000 abstract 5
- DHMQDGOQFOQNFH-CNRUNOGKSA-N 2-amino-2-tritioacetic acid Chemical compound [3H]C(N)C(O)=O DHMQDGOQFOQNFH-CNRUNOGKSA-N 0.000 abstract 1
- 206010061218 Inflammation Diseases 0.000 abstract 1
- QNAYBMKLOCPYGJ-REOHCLBHSA-N L-alanine Chemical compound C[C@H](N)C(O)=O QNAYBMKLOCPYGJ-REOHCLBHSA-N 0.000 abstract 1
- 108060008683 Tumor Necrosis Factor Receptor Proteins 0.000 abstract 1
- 235000004279 alanine Nutrition 0.000 abstract 1
- 235000001014 amino acid Nutrition 0.000 abstract 1
- 230000003247 decreasing effect Effects 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 238000009472 formulation Methods 0.000 abstract 1
- 230000013632 homeostatic process Effects 0.000 abstract 1
- 230000004054 inflammatory process Effects 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 102000003298 tumor necrosis factor receptor Human genes 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/115—Fatty acids or derivatives thereof; Fats or oils
- A23L33/12—Fatty acids or derivatives thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/13—Nucleic acids or derivatives thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
- A23L33/175—Amino acids
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/40—Complete food formulations for specific consumer groups or specific purposes, e.g. infant formula
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Nutrition Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Mycology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Pediatric Medicine (AREA)
- Obesity (AREA)
- Diabetes (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
Abstract
LA INVENCION CONTEMPLA EL USO DE AL MENOS UN AMINOACIDO SELECCIONADO DEL GRUPO GLICINA, ALANINA Y SERINA, O LAS SALES FISIOLOGICAMENTE ACEPTABLES DE LOS MISMOS EN LA PREPARACION DE UN MEDICAMENTO O FORMULACION NUTRICIONAL PARA LA DISMINUCION DE LOS NIVELES DE FACTOR DE NECROSIS TUMORAL (TNF) EN PACIENTES EN LOS QUE DICHOS NIVELES SOBREPASAN LOS MEDIADOS POR LA HOMEOSTASIS FISIOLOGICA Y LA INFLAMACION LOCAL. TAL DISMINUCION DE LOS NIVELES DE TNF PUEDE LOGRARSE POR INHIBICION O DISMINUCION DE: (I) LA PRODUCCION DE FACTOR DE NECROSIS TUMORAL (TNF) POR LAS CELULAS DEL TIPO MACROFAGO; (II) LA LIBERACION DE TNF POR LAS CELULAS DE TIPO MACROFAGO; Y/O (III) LA UNION DE TNF POR RECEPTORES DE TNF.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08392694 US5656608B1 (en) | 1995-02-23 | 1995-02-23 | Amino acid compositions and methods of treatment using same |
GBGB9512100.0A GB9512100D0 (en) | 1995-06-14 | 1995-06-14 | Improvements in or relating to organic compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2145997T3 true ES2145997T3 (es) | 2000-07-16 |
Family
ID=26307213
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES96904849T Expired - Lifetime ES2145997T3 (es) | 1995-02-23 | 1996-02-22 | Composiciones de aminoacidos y uso de las mismas en la nutricion clinica. |
Country Status (18)
Country | Link |
---|---|
EP (1) | EP0810829B1 (es) |
JP (1) | JPH11501301A (es) |
KR (1) | KR19980702436A (es) |
CN (1) | CN1175887A (es) |
AT (1) | ATE191615T1 (es) |
AU (1) | AU710527B2 (es) |
BR (1) | BR9607336A (es) |
CA (1) | CA2210499A1 (es) |
CZ (1) | CZ266797A3 (es) |
DE (1) | DE69607750T2 (es) |
DK (1) | DK0810829T3 (es) |
ES (1) | ES2145997T3 (es) |
FI (1) | FI972744A (es) |
HU (1) | HUP9800049A3 (es) |
NO (1) | NO973884L (es) |
PL (1) | PL182205B1 (es) |
PT (1) | PT810829E (es) |
WO (1) | WO1996025861A1 (es) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9512100D0 (en) * | 1995-06-14 | 1995-08-09 | Sandoz Nutrition Ltd | Improvements in or relating to organic compounds |
CA2260886A1 (en) * | 1996-07-30 | 1998-02-05 | Novartis Nutrition Ag | Amino acid composition and use thereof in treating tumor growth and metastasis |
US6096785A (en) * | 1996-07-30 | 2000-08-01 | Novartis Nutrition Ag | Amino acid compositions and use thereof in treating renal dysfunction |
GB9701674D0 (en) * | 1997-01-28 | 1997-03-19 | Novartis Nutrition Ag | Use of organic compounds |
ATE266395T1 (de) * | 1997-06-05 | 2004-05-15 | Novartis Nutrition Ag | Glycin zur vorbeugung oder behandlung von transplantatabstossungen |
WO1999004781A1 (fr) * | 1997-07-28 | 1999-02-04 | The Institute Of Physical And Chemical Research | Agent promoteur de protection et de survie des cellules du systeme nerveux central |
US6143786A (en) * | 1999-02-02 | 2000-11-07 | Novartis Nutrition Ag | Oral arginine and insulin secretion |
US6808902B1 (en) | 1999-11-12 | 2004-10-26 | Amgen Inc. | Process for correction of a disulfide misfold in IL-1Ra Fc fusion molecules |
CN1547486A (zh) | 2001-06-26 | 2004-11-17 | 抗opgl抗体 | |
NL1019368C2 (nl) | 2001-11-14 | 2003-05-20 | Nutricia Nv | Preparaat voor het verbeteren van receptorwerking. |
DE10257360A1 (de) * | 2002-12-09 | 2004-07-08 | Fresenius Kabi Deutschland Gmbh | Gastro-intestinal verabreichbare Formulierung und deren Verwendung |
US20060280776A1 (en) | 2003-09-02 | 2006-12-14 | Masafumi Koide | Diet food |
EP1591118A1 (en) | 2004-04-27 | 2005-11-02 | Nutri-Fit GmbH & Co. KG | Use of melatonin in preventing postoperative complications |
KR100555904B1 (ko) * | 2004-05-19 | 2006-03-03 | 주식회사 오스코텍 | 큰느타리버섯과 오가피의 혼합 생약재 추출물 및 이를유효성분으로 하는 골다공증 예방 및 치료용 조성물 |
EP2032170B1 (en) * | 2006-06-14 | 2012-11-28 | N.V. Nutricia | Anti-inflammatory composition comprising glycine and lactoferrin and the use thereof |
CA2709660C (en) | 2008-01-04 | 2018-06-05 | Nestec S.A. | Compositions comprising unsaturated fatty acids and nitric oxide releasing compounds and use thereof for enhancing cognitive and related functions |
US20100179089A1 (en) * | 2009-01-13 | 2010-07-15 | Deutz Nicolaas E P | Compositions and Methods to Manage the Inflammatory Basis of Chronic Disease Conditions and Maintain an Optimal Immune Response in Elderly |
AU2010258888B2 (en) * | 2009-06-08 | 2014-08-07 | Ocera Therapeutics, Inc. | Treatment of portal hypertension and restoration of liver function using L-ornithine phenylacetate |
KR101213825B1 (ko) * | 2010-07-16 | 2012-12-18 | 서울대학교산학협력단 | 세린을 유효성분으로 함유하는 지방간 질환의 예방 및 치료용 조성물 |
JP6000253B2 (ja) | 2010-09-24 | 2016-09-28 | ユニバーシティ オブ フロリダ リサーチ ファンデーション インコーポレーティッド | 胃腸機能を改善するための材料および方法 |
MX361647B (es) | 2013-03-11 | 2018-12-13 | Univ Florida | Materiales y métodos para mejorar la función pulmonar y para la prevención y/o tratamiento de complicaciones pulmonares inducidas por radiación. |
US20170326088A1 (en) | 2014-11-24 | 2017-11-16 | Entrinsic Health Solutions, Llc | Amino acid compositions for the treatment of symptoms of disease |
CN108348493B (zh) * | 2015-10-02 | 2022-03-29 | 荷兰纽迪希亚公司 | 甘氨酸用于过敏性患者的耐受性诱导 |
FR3041882B1 (fr) * | 2015-10-06 | 2019-04-12 | Universite D'angers | Preparation pharmaceutique pour le traitement preventif de lesions d'ischenie reperfusion |
BR112019006742A2 (pt) | 2016-10-04 | 2019-09-03 | Entrinsic Health Solutions Inc | composições de aminoácido e usos das mesmas |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2591893B1 (fr) * | 1985-12-19 | 1988-11-10 | Centre Nat Rech Scient | Compositions nutritionnelles carencees en methionine destinees a inhiber le developpement et la dissemination des tumeurs malignes chez les mammiferes |
US4988724A (en) * | 1988-12-09 | 1991-01-29 | Board Of Regents, The University Of Texas System | Methods and improved formulations for the determination and treatment of malignant disease in patients |
WO1993005780A1 (en) * | 1991-09-27 | 1993-04-01 | Board Of Regents, The University Of Texas System | Amino acids containing parenteral formulations for the treatment of hypotension and related pathologies |
US5571783A (en) * | 1993-03-09 | 1996-11-05 | Clintec Nutrition Company | Composition and method for treating patients with hepatic disease |
-
1996
- 1996-02-22 AU AU48795/96A patent/AU710527B2/en not_active Ceased
- 1996-02-22 JP JP8525404A patent/JPH11501301A/ja active Pending
- 1996-02-22 AT AT96904849T patent/ATE191615T1/de not_active IP Right Cessation
- 1996-02-22 ES ES96904849T patent/ES2145997T3/es not_active Expired - Lifetime
- 1996-02-22 PT PT96904849T patent/PT810829E/pt unknown
- 1996-02-22 PL PL96321238A patent/PL182205B1/pl unknown
- 1996-02-22 EP EP96904849A patent/EP0810829B1/en not_active Expired - Lifetime
- 1996-02-22 CZ CZ972667A patent/CZ266797A3/cs unknown
- 1996-02-22 BR BR9607336A patent/BR9607336A/pt not_active Application Discontinuation
- 1996-02-22 DK DK96904849T patent/DK0810829T3/da active
- 1996-02-22 CN CN96192066A patent/CN1175887A/zh active Pending
- 1996-02-22 CA CA002210499A patent/CA2210499A1/en not_active Abandoned
- 1996-02-22 DE DE69607750T patent/DE69607750T2/de not_active Expired - Fee Related
- 1996-02-22 KR KR1019970705835A patent/KR19980702436A/ko not_active Application Discontinuation
- 1996-02-22 HU HU9800049A patent/HUP9800049A3/hu unknown
- 1996-02-22 WO PCT/EP1996/000739 patent/WO1996025861A1/en not_active Application Discontinuation
-
1997
- 1997-06-25 FI FI972744A patent/FI972744A/fi unknown
- 1997-08-22 NO NO973884A patent/NO973884L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
EP0810829B1 (en) | 2000-04-12 |
CA2210499A1 (en) | 1996-08-29 |
CZ266797A3 (cs) | 1998-03-18 |
PL182205B1 (pl) | 2001-11-30 |
NO973884D0 (no) | 1997-08-22 |
NO973884L (no) | 1997-10-17 |
PT810829E (pt) | 2000-08-31 |
PL321238A1 (en) | 1997-11-24 |
DE69607750D1 (de) | 2000-05-18 |
HUP9800049A2 (hu) | 1998-05-28 |
ATE191615T1 (de) | 2000-04-15 |
WO1996025861A1 (en) | 1996-08-29 |
BR9607336A (pt) | 1997-11-25 |
HUP9800049A3 (en) | 1999-01-28 |
EP0810829A1 (en) | 1997-12-10 |
JPH11501301A (ja) | 1999-02-02 |
DE69607750T2 (de) | 2000-08-31 |
MX9706140A (es) | 1997-11-29 |
DK0810829T3 (da) | 2000-08-28 |
AU4879596A (en) | 1996-09-11 |
KR19980702436A (ko) | 1998-07-15 |
CN1175887A (zh) | 1998-03-11 |
FI972744A0 (fi) | 1997-06-25 |
AU710527B2 (en) | 1999-09-23 |
FI972744A (fi) | 1997-08-22 |
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Legal Events
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