ES2167889T3 - Composiciones solidas adecuadas para administracion oral que comprenden tartrato de l-carnitina colina o tartrato de alcanoil-l-carnitina colina. - Google Patents
Composiciones solidas adecuadas para administracion oral que comprenden tartrato de l-carnitina colina o tartrato de alcanoil-l-carnitina colina.Info
- Publication number
- ES2167889T3 ES2167889T3 ES98917598T ES98917598T ES2167889T3 ES 2167889 T3 ES2167889 T3 ES 2167889T3 ES 98917598 T ES98917598 T ES 98917598T ES 98917598 T ES98917598 T ES 98917598T ES 2167889 T3 ES2167889 T3 ES 2167889T3
- Authority
- ES
- Spain
- Prior art keywords
- colina
- carnitine
- oral administration
- compositions suitable
- carnitina
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- PHIQHXFUZVPYII-ZCFIWIBFSA-N (R)-carnitine Chemical compound C[N+](C)(C)C[C@H](O)CC([O-])=O PHIQHXFUZVPYII-ZCFIWIBFSA-N 0.000 title abstract 3
- 239000008247 solid mixture Substances 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- QWJSAWXRUVVRLH-LREBCSMRSA-M 2-hydroxyethyl(trimethyl)azanium;(2r,3r)-2,3,4-trihydroxy-4-oxobutanoate Chemical compound C[N+](C)(C)CCO.OC(=O)[C@H](O)[C@@H](O)C([O-])=O QWJSAWXRUVVRLH-LREBCSMRSA-M 0.000 abstract 1
- FEWJPZIEWOKRBE-JCYAYHJZSA-N Dextrotartaric acid Chemical compound OC(=O)[C@H](O)[C@@H](O)C(O)=O FEWJPZIEWOKRBE-JCYAYHJZSA-N 0.000 abstract 1
- 125000001589 carboacyl group Chemical group 0.000 abstract 1
- 235000013402 health food Nutrition 0.000 abstract 1
- 239000002417 nutraceutical Substances 0.000 abstract 1
- 235000021436 nutraceutical agent Nutrition 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 229940127557 pharmaceutical product Drugs 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
- 229940095064 tartrate Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/235—Saturated compounds containing more than one carboxyl group
- C07C59/245—Saturated compounds containing more than one carboxyl group containing hydroxy or O-metal groups
- C07C59/255—Tartaric acid
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/105—Aliphatic or alicyclic compounds
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/174—Vitamins
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
- A23L33/175—Amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C215/40—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton with quaternised nitrogen atoms bound to carbon atoms of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C229/22—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated the carbon skeleton being further substituted by oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Polymers & Plastics (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Zoology (AREA)
- Animal Husbandry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nutrition Science (AREA)
- Public Health (AREA)
- Cardiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Mycology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Hospice & Palliative Care (AREA)
- Heart & Thoracic Surgery (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Cosmetics (AREA)
- Fodder In General (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Composiciones sólidas adecuadas para administración oral que comprenden tartrato de L-carnitina colina o tartrato de alcanoil-L-carnitinacolina. La presente invención se relaciona con sales estables, no higroscópicas, farmacológicamente aceptables de L-carnitina y alcanoil(inferior)-L-carnitina que se prestan por sí mismas muy bien para la preparación de composiciones sólidas administrables por vía oral, las cuales son de utilidad no solo como productos farmacéuticos sino también para el mercado de "productos alimenti- cios para la salud" y "nutracéutico". La presente invención se relaciona igualmente con dichas composiciones.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT97RM000222A IT1291143B1 (it) | 1997-04-18 | 1997-04-18 | Composizioni solide atte alla somministrazione orale comprendenti l-carnitina colina tartrato o una alcanoil l-carnitina colina |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2167889T3 true ES2167889T3 (es) | 2002-05-16 |
Family
ID=11404982
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES98917598T Expired - Lifetime ES2167889T3 (es) | 1997-04-18 | 1998-04-08 | Composiciones solidas adecuadas para administracion oral que comprenden tartrato de l-carnitina colina o tartrato de alcanoil-l-carnitina colina. |
Country Status (17)
Country | Link |
---|---|
US (1) | US6080786A (es) |
EP (1) | EP0975581B1 (es) |
JP (1) | JP4046361B2 (es) |
KR (1) | KR100562052B1 (es) |
AT (1) | ATE208759T1 (es) |
AU (1) | AU731223B2 (es) |
BR (1) | BR9808908B1 (es) |
CA (1) | CA2286631C (es) |
DE (1) | DE69802518T2 (es) |
DK (1) | DK0975581T3 (es) |
ES (1) | ES2167889T3 (es) |
HK (1) | HK1025562A1 (es) |
IT (1) | IT1291143B1 (es) |
NZ (1) | NZ500535A (es) |
PT (1) | PT975581E (es) |
SI (1) | SI0975581T1 (es) |
WO (1) | WO1998047857A1 (es) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1306147B1 (it) * | 1999-05-28 | 2001-05-30 | Biosalts Srl | Derivati di principi attivi ad attivita' terapeutica e/o nutrizionalee composizioni atte alla somministrazione orale contenenti tali |
IT1306186B1 (it) * | 1999-09-03 | 2001-05-30 | Biosalts Srl | Sali non igroscopici di principi attivi ad attivita' terapeutica e/onutrizionale e composizioni atte alla somministrazione orale |
DE19956772A1 (de) * | 1999-11-25 | 2001-06-07 | Basf Ag | Verwendung von y-Butyrobetain Salzen zur Herstellung von Zubereitungen für die menschliche und tierische Ernährung |
DE10350140A1 (de) * | 2003-03-28 | 2004-10-14 | Martin Schymura | Fruchtgummizusammensetzung |
BR102016009579A2 (pt) * | 2016-04-28 | 2017-10-31 | Geralatex Indl E Coml Prod Agro Florestais | Nutritional food supplement formulated on the basis of pulp or humid watermelon factor, modified by hydration or reidrating, also known as tapioca, used as a source of carbohydrates and nucleus for formulations for food and dietary supplementation or, still as a partial substitute of meals for athletes or practicers of physical activities, its compositions and process |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1153640A (en) * | 1967-04-10 | 1969-05-29 | Soc D Etudes Prod Chimique | A Carnitin Salt |
FR2529545B1 (fr) * | 1982-07-02 | 1985-05-31 | Sanofi Sa | Nouveaux sels de carnitine ainsi que leur procede de preparation |
EP0150688B1 (en) * | 1983-12-28 | 1987-04-22 | Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. | Salts of l-carnitine and alkanoyl l-carnitines and process for preparing same |
US5001117A (en) * | 1989-03-07 | 1991-03-19 | Pharmacaps, Inc. | Use of lecithin to restore olfaction and taste |
CA2018137C (en) * | 1989-06-14 | 2000-01-11 | Thomas Scholl | L-carnitine magnesium citrate |
US5073376A (en) * | 1989-12-22 | 1991-12-17 | Lonza Ltd. | Preparations containing l-carnitine |
IT1261688B (it) * | 1993-05-28 | 1996-05-29 | Avantgarde Spa | Uso di esteri sull'ossidrile della l-carnitina per produrre composizioni farmaceutiche per il trattamento di affezioni cutanee. |
-
1997
- 1997-04-18 IT IT97RM000222A patent/IT1291143B1/it active IP Right Grant
-
1998
- 1998-04-04 US US09/402,650 patent/US6080786A/en not_active Expired - Fee Related
- 1998-04-08 CA CA002286631A patent/CA2286631C/en not_active Expired - Fee Related
- 1998-04-08 AU AU70777/98A patent/AU731223B2/en not_active Ceased
- 1998-04-08 ES ES98917598T patent/ES2167889T3/es not_active Expired - Lifetime
- 1998-04-08 JP JP54538898A patent/JP4046361B2/ja not_active Expired - Fee Related
- 1998-04-08 DE DE69802518T patent/DE69802518T2/de not_active Expired - Lifetime
- 1998-04-08 PT PT98917598T patent/PT975581E/pt unknown
- 1998-04-08 WO PCT/IT1998/000080 patent/WO1998047857A1/en not_active Application Discontinuation
- 1998-04-08 BR BRPI9808908-0A patent/BR9808908B1/pt not_active IP Right Cessation
- 1998-04-08 NZ NZ500535A patent/NZ500535A/en unknown
- 1998-04-08 AT AT98917598T patent/ATE208759T1/de not_active IP Right Cessation
- 1998-04-08 EP EP98917598A patent/EP0975581B1/en not_active Expired - Lifetime
- 1998-04-08 DK DK98917598T patent/DK0975581T3/da active
- 1998-04-08 SI SI9830051T patent/SI0975581T1/xx unknown
- 1998-04-08 KR KR1019997009473A patent/KR100562052B1/ko not_active IP Right Cessation
-
2000
- 2000-04-20 HK HK00102419A patent/HK1025562A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
DK0975581T3 (da) | 2002-03-25 |
HK1025562A1 (en) | 2000-11-17 |
CA2286631A1 (en) | 1998-10-29 |
KR20010006386A (ko) | 2001-01-26 |
WO1998047857A1 (en) | 1998-10-29 |
JP2002512613A (ja) | 2002-04-23 |
IT1291143B1 (it) | 1998-12-29 |
EP0975581A1 (en) | 2000-02-02 |
SI0975581T1 (en) | 2002-06-30 |
AU7077798A (en) | 1998-11-13 |
AU731223B2 (en) | 2001-03-29 |
BR9808908B1 (pt) | 2011-02-08 |
KR100562052B1 (ko) | 2006-03-17 |
JP4046361B2 (ja) | 2008-02-13 |
ATE208759T1 (de) | 2001-11-15 |
CA2286631C (en) | 2008-07-08 |
NZ500535A (en) | 2001-03-30 |
BR9808908A (pt) | 2000-08-01 |
DE69802518T2 (de) | 2002-05-16 |
US6080786A (en) | 2000-06-27 |
DE69802518D1 (de) | 2001-12-20 |
PT975581E (pt) | 2002-04-29 |
ITRM970222A1 (it) | 1998-10-18 |
EP0975581B1 (en) | 2001-11-14 |
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