MX9706140A - Composiciones de aminoacidos y el uso de las mismas en nutricion clinica. - Google Patents
Composiciones de aminoacidos y el uso de las mismas en nutricion clinica.Info
- Publication number
- MX9706140A MX9706140A MX9706140A MX9706140A MX9706140A MX 9706140 A MX9706140 A MX 9706140A MX 9706140 A MX9706140 A MX 9706140A MX 9706140 A MX9706140 A MX 9706140A MX 9706140 A MX9706140 A MX 9706140A
- Authority
- MX
- Mexico
- Prior art keywords
- tnf
- amino acid
- diminution
- levels
- acid compositions
- Prior art date
Links
- 150000001413 amino acids Chemical class 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title abstract 2
- 235000016709 nutrition Nutrition 0.000 title abstract 2
- 230000035764 nutrition Effects 0.000 title 1
- 108060008682 Tumor Necrosis Factor Proteins 0.000 abstract 7
- 102000003390 tumor necrosis factor Human genes 0.000 abstract 7
- DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Chemical compound NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 abstract 2
- MTCFGRXMJLQNBG-REOHCLBHSA-N (2S)-2-Amino-3-hydroxypropansäure Chemical compound OC[C@H](N)C(O)=O MTCFGRXMJLQNBG-REOHCLBHSA-N 0.000 abstract 1
- 239000004471 Glycine Substances 0.000 abstract 1
- 206010061218 Inflammation Diseases 0.000 abstract 1
- QNAYBMKLOCPYGJ-REOHCLBHSA-N L-alanine Chemical compound C[C@H](N)C(O)=O QNAYBMKLOCPYGJ-REOHCLBHSA-N 0.000 abstract 1
- MTCFGRXMJLQNBG-UHFFFAOYSA-N Serine Natural products OCC(N)C(O)=O MTCFGRXMJLQNBG-UHFFFAOYSA-N 0.000 abstract 1
- 108060008683 Tumor Necrosis Factor Receptor Proteins 0.000 abstract 1
- 235000004279 alanine Nutrition 0.000 abstract 1
- 235000001014 amino acid Nutrition 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 238000009472 formulation Methods 0.000 abstract 1
- 230000013632 homeostatic process Effects 0.000 abstract 1
- 230000004054 inflammatory process Effects 0.000 abstract 1
- 230000005764 inhibitory process Effects 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 102000003298 tumor necrosis factor receptor Human genes 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/115—Fatty acids or derivatives thereof; Fats or oils
- A23L33/12—Fatty acids or derivatives thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/13—Nucleic acids or derivatives thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
- A23L33/175—Amino acids
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/40—Complete food formulations for specific consumer groups or specific purposes, e.g. infant formula
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Nutrition Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Mycology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Pediatric Medicine (AREA)
- Obesity (AREA)
- Diabetes (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
Abstract
La presente invencion proporciona el uso de al menos un aminoácido seleccionado del grupo que consiste de la glicina, alanina y serina, o las sales fisiologicamente aceptables de los mismos, en la preparacion de un medicamente o formulacion nutricional, para la disminucion de los niveles del factor de la necrosis en tumores (TNF) en pacientes en quienes esos niveles están elevados más allá de aquéllos que median la homeostasis fisiologica y la inflamacion local. Esa disminucion de los niveles del TNF se pueden lograr, inter alia, mediante la inhibicion o disminucion de: (i) la produccion del factor de la necrosis de tumores (TNF) por células del tipo macrofagos; (ii) la liberacion del TNF por células del tipo macrofagos; y/o (iii) el enlazamiento del TNF por receptores del TNF.
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08392694 | 1995-02-23 | ||
| US08392694 US5656608B1 (en) | 1995-02-23 | 1995-02-23 | Amino acid compositions and methods of treatment using same |
| GB9512100.0 | 1995-06-14 | ||
| GBGB9512100.0A GB9512100D0 (en) | 1995-06-14 | 1995-06-14 | Improvements in or relating to organic compounds |
| PCT/EP1996/000739 WO1996025861A1 (en) | 1995-02-23 | 1996-02-22 | Amino acid compositions and use thereof in clinical nutrition |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX9706140A true MX9706140A (es) | 1997-11-29 |
| MXPA97006140A MXPA97006140A (es) | 1998-07-03 |
Family
ID=
Also Published As
| Publication number | Publication date |
|---|---|
| EP0810829B1 (en) | 2000-04-12 |
| CA2210499A1 (en) | 1996-08-29 |
| CZ266797A3 (cs) | 1998-03-18 |
| ES2145997T3 (es) | 2000-07-16 |
| PL182205B1 (pl) | 2001-11-30 |
| NO973884D0 (no) | 1997-08-22 |
| NO973884L (no) | 1997-10-17 |
| PT810829E (pt) | 2000-08-31 |
| PL321238A1 (en) | 1997-11-24 |
| DE69607750D1 (de) | 2000-05-18 |
| HUP9800049A2 (hu) | 1998-05-28 |
| ATE191615T1 (de) | 2000-04-15 |
| WO1996025861A1 (en) | 1996-08-29 |
| BR9607336A (pt) | 1997-11-25 |
| HUP9800049A3 (en) | 1999-01-28 |
| EP0810829A1 (en) | 1997-12-10 |
| JPH11501301A (ja) | 1999-02-02 |
| DE69607750T2 (de) | 2000-08-31 |
| DK0810829T3 (da) | 2000-08-28 |
| AU4879596A (en) | 1996-09-11 |
| KR19980702436A (ko) | 1998-07-15 |
| CN1175887A (zh) | 1998-03-11 |
| FI972744A0 (fi) | 1997-06-25 |
| AU710527B2 (en) | 1999-09-23 |
| FI972744A (fi) | 1997-08-22 |
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