FR3041882B1 - Preparation pharmaceutique pour le traitement preventif de lesions d'ischenie reperfusion - Google Patents
Preparation pharmaceutique pour le traitement preventif de lesions d'ischenie reperfusion Download PDFInfo
- Publication number
- FR3041882B1 FR3041882B1 FR1502083A FR1502083A FR3041882B1 FR 3041882 B1 FR3041882 B1 FR 3041882B1 FR 1502083 A FR1502083 A FR 1502083A FR 1502083 A FR1502083 A FR 1502083A FR 3041882 B1 FR3041882 B1 FR 3041882B1
- Authority
- FR
- France
- Prior art keywords
- pharmaceutical preparation
- ischenie
- reperfusion
- lesions
- preventive treatment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 239000000825 pharmaceutical preparation Substances 0.000 title abstract 2
- 230000003902 lesion Effects 0.000 title 1
- 230000003449 preventive effect Effects 0.000 title 1
- 230000010410 reperfusion Effects 0.000 title 1
- YGPSJZOEDVAXAB-UHFFFAOYSA-N kynurenine Chemical compound OC(=O)C(N)CC(=O)C1=CC=CC=C1N YGPSJZOEDVAXAB-UHFFFAOYSA-N 0.000 abstract 2
- 206010063837 Reperfusion injury Diseases 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000001120 cytoprotective effect Effects 0.000 abstract 1
- 208000012947 ischemia reperfusion injury Diseases 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Urology & Nephrology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
L'invention concerne une préparation pharmaceutique comprenant un composé aux effets cytoprotecteurs de type kynurénine ou son sel, en mélange racémique ou non-racémique, pour le traitement des lésions d'ischémie reperfusion. L'invention concerne également une méthode thérapeutique utilisant cette préparation.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR1502083A FR3041882B1 (fr) | 2015-10-06 | 2015-10-06 | Preparation pharmaceutique pour le traitement preventif de lesions d'ischenie reperfusion |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR1502083 | 2015-10-06 | ||
FR1502083A FR3041882B1 (fr) | 2015-10-06 | 2015-10-06 | Preparation pharmaceutique pour le traitement preventif de lesions d'ischenie reperfusion |
Publications (2)
Publication Number | Publication Date |
---|---|
FR3041882A1 FR3041882A1 (fr) | 2017-04-07 |
FR3041882B1 true FR3041882B1 (fr) | 2019-04-12 |
Family
ID=56137363
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR1502083A Expired - Fee Related FR3041882B1 (fr) | 2015-10-06 | 2015-10-06 | Preparation pharmaceutique pour le traitement preventif de lesions d'ischenie reperfusion |
Country Status (1)
Country | Link |
---|---|
FR (1) | FR3041882B1 (fr) |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6265442B1 (en) * | 1990-09-13 | 2001-07-24 | The General Hospital Corporation | Treatment of neurological diseases by increasing brain concentrations of kynurenic acid |
AU710527B2 (en) * | 1995-02-23 | 1999-09-23 | Novartis Nutrition Ag | Amino acid compositions and use thereof in clinical nutrition |
TWI386396B (zh) * | 2008-06-20 | 2013-02-21 | Standard Chem & Pharm Co Ltd | 阿朴芬化合物與含羧基藥劑之醫藥可接受鹽類及其製備方法 |
-
2015
- 2015-10-06 FR FR1502083A patent/FR3041882B1/fr not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
FR3041882A1 (fr) | 2017-04-07 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PLFP | Fee payment |
Year of fee payment: 2 |
|
PLSC | Search report ready |
Effective date: 20170407 |
|
PLFP | Fee payment |
Year of fee payment: 3 |
|
PLFP | Fee payment |
Year of fee payment: 4 |
|
PLFP | Fee payment |
Year of fee payment: 5 |
|
ST | Notification of lapse |
Effective date: 20210605 |