ES2105334T3 - Sistema terapeutico percutaneo para la administracion de fisostigmina en la piel y el procedimiento para su obtencion. - Google Patents
Sistema terapeutico percutaneo para la administracion de fisostigmina en la piel y el procedimiento para su obtencion.Info
- Publication number
- ES2105334T3 ES2105334T3 ES93923558T ES93923558T ES2105334T3 ES 2105334 T3 ES2105334 T3 ES 2105334T3 ES 93923558 T ES93923558 T ES 93923558T ES 93923558 T ES93923558 T ES 93923558T ES 2105334 T3 ES2105334 T3 ES 2105334T3
- Authority
- ES
- Spain
- Prior art keywords
- pct
- physostigmine
- administration
- skin
- therapeutic system
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
- A61K9/7061—Polyacrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Materials For Medical Uses (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Saccharide Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
SE DESCRIBE UN SISTEMA TERAPEUTICO TRANSDERMAL PARA ADMINISTRACION DE FISOSTIGMINA A TRAVES DE LA PIEL, COMPRENDIENDO EL SISTEMA UNA PELICULA POSTERIOR QUE ES IMPERMEABLE A LA SUSTANCIA ACTIVA, UNA CAPA DE RESERVA ADHESIVA CONTENIENDO 40 HASTA 90 % EN PESO DE MATERIAL POLIMERO Y 0,1 HASTA 20 % EN PESO DE BASE FISOSTIGMINA O UNA DE SUS SALES ACEPTABLE FARMACEUTICAMENTE, MAS UNA PELICULA PROTECTORA DESMONTABLE QUE CUBRE LA CAPA DE RESERVA. LA CAPA DE RESERVA CONTIENE MATERIAL POLIMERO ACRILATO Y/O METACRILATO Y 0,1 HASTA 40 % EN PESO DE UN PLASTIFICADOR QUE CONTIENE GRUPOS HIDROXIL Y UN VALOR HLB ENTRE 1,1 Y 12,0.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE4238223A DE4238223C1 (de) | 1992-11-12 | 1992-11-12 | Transdermales therapeutisches System zur Verabreichung von Physostigmin an die Haut und Verfahren zu dessen Herstellung |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2105334T3 true ES2105334T3 (es) | 1997-10-16 |
Family
ID=6472735
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES93923558T Expired - Lifetime ES2105334T3 (es) | 1992-11-12 | 1993-10-27 | Sistema terapeutico percutaneo para la administracion de fisostigmina en la piel y el procedimiento para su obtencion. |
Country Status (32)
Country | Link |
---|---|
US (1) | US5698216A (es) |
EP (1) | EP0667774B1 (es) |
JP (1) | JP3407073B2 (es) |
KR (1) | KR100254573B1 (es) |
CN (1) | CN1088457A (es) |
AT (1) | ATE156356T1 (es) |
AU (1) | AU684256B2 (es) |
CA (1) | CA2147274C (es) |
CZ (1) | CZ284008B6 (es) |
DE (2) | DE4238223C1 (es) |
DK (1) | DK0667774T3 (es) |
EE (1) | EE03135B1 (es) |
EG (1) | EG20527A (es) |
ES (1) | ES2105334T3 (es) |
FI (1) | FI952269A (es) |
GR (1) | GR3024720T3 (es) |
HR (1) | HRP931391B1 (es) |
HU (1) | HUT72963A (es) |
IL (1) | IL107547A (es) |
LT (1) | LT3107B (es) |
LV (1) | LV10749B (es) |
MD (1) | MD937C2 (es) |
MY (1) | MY111373A (es) |
NO (1) | NO306760B1 (es) |
NZ (1) | NZ257136A (es) |
PL (1) | PL172999B1 (es) |
RU (1) | RU2108812C1 (es) |
SI (1) | SI9300589A (es) |
SK (1) | SK280185B6 (es) |
WO (1) | WO1994010999A1 (es) |
YU (1) | YU71293A (es) |
ZA (1) | ZA938413B (es) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE4446600A1 (de) * | 1994-12-24 | 1996-06-27 | Lohmann Therapie Syst Lts | Transdermale Resorption von Wirkstoffen aus unterkühlten Schmelzen |
DE19828273B4 (de) * | 1998-06-25 | 2005-02-24 | Lts Lohmann Therapie-Systeme Ag | Transdermales therapeutisches System, enthaltend Hormone und Kristallisationsinhibitoren |
DE19923551A1 (de) * | 1999-05-21 | 2000-11-30 | Lohmann Therapie Syst Lts | Pharmazeutisches Präparat mit dem Wirkstoff Diamorphin und seine Verwendung in einem Verfahren zur Behandlung der Opiatsucht |
AT500143A1 (de) * | 2004-04-22 | 2005-11-15 | Sanochemia Pharmazeutika Ag | Cholinesterase-inhibitoren in liposomen sowie deren herstellung und verwendung |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3921363A (en) | 1974-05-17 | 1975-11-25 | Preston Metal & Roofing Prod | Cross member with end connector |
IL72684A (en) * | 1984-08-14 | 1989-02-28 | Israel State | Pharmaceutical compositions for controlled transdermal delivery of cholinergic or anticholinergic basic drugs |
US4680172A (en) | 1985-03-05 | 1987-07-14 | Ciba-Geigy Corporation | Devices and methods for treating memory impairment |
DE3843239C1 (es) | 1988-12-22 | 1990-02-22 | Lohmann Therapie Syst Lts | |
DE3843238C1 (es) * | 1988-12-22 | 1990-02-22 | Lohmann Therapie Syst Lts | |
US5350581A (en) * | 1989-12-14 | 1994-09-27 | Pharmetrix Corporation | Method for manufacturing transdermal devices |
NZ237241A (en) * | 1990-03-02 | 1993-11-25 | Pharmetrix Corp | Method for increasing the storage stability of physostigmine |
WO1991015176A1 (en) * | 1990-04-06 | 1991-10-17 | Pharmetrix Corporation | Device and method for enhanced administration of physostigmine |
JP4355469B2 (ja) * | 2002-03-08 | 2009-11-04 | 日本碍子株式会社 | アルミナ担持担体、触媒体及びアルミナ担持担体の製造方法 |
-
1992
- 1992-11-12 DE DE4238223A patent/DE4238223C1/de not_active Expired - Lifetime
-
1993
- 1993-10-27 DE DE59307089T patent/DE59307089D1/de not_active Expired - Lifetime
- 1993-10-27 RU RU95113504A patent/RU2108812C1/ru active
- 1993-10-27 ES ES93923558T patent/ES2105334T3/es not_active Expired - Lifetime
- 1993-10-27 CZ CZ951244A patent/CZ284008B6/cs not_active IP Right Cessation
- 1993-10-27 KR KR1019950701873A patent/KR100254573B1/ko not_active IP Right Cessation
- 1993-10-27 WO PCT/EP1993/002970 patent/WO1994010999A1/de active IP Right Grant
- 1993-10-27 CA CA002147274A patent/CA2147274C/en not_active Expired - Fee Related
- 1993-10-27 JP JP51164994A patent/JP3407073B2/ja not_active Expired - Fee Related
- 1993-10-27 AU AU53385/94A patent/AU684256B2/en not_active Ceased
- 1993-10-27 US US08/433,459 patent/US5698216A/en not_active Expired - Lifetime
- 1993-10-27 HU HU9501390A patent/HUT72963A/hu unknown
- 1993-10-27 NZ NZ257136A patent/NZ257136A/en unknown
- 1993-10-27 AT AT93923558T patent/ATE156356T1/de active
- 1993-10-27 DK DK93923558.6T patent/DK0667774T3/da active
- 1993-10-27 PL PL93308531A patent/PL172999B1/pl unknown
- 1993-10-27 SK SK593-95A patent/SK280185B6/sk unknown
- 1993-10-27 EP EP93923558A patent/EP0667774B1/de not_active Expired - Lifetime
- 1993-11-05 LV LVP-93-1204A patent/LV10749B/lv unknown
- 1993-11-09 IL IL10754793A patent/IL107547A/en not_active IP Right Cessation
- 1993-11-10 YU YU71293A patent/YU71293A/sh unknown
- 1993-11-11 HR HRP4238223.8A patent/HRP931391B1/xx not_active IP Right Cessation
- 1993-11-11 MY MYPI93002363A patent/MY111373A/en unknown
- 1993-11-11 EG EG71993A patent/EG20527A/xx active
- 1993-11-11 CN CN93112909A patent/CN1088457A/zh active Pending
- 1993-11-11 ZA ZA938413A patent/ZA938413B/xx unknown
- 1993-11-11 SI SI9300589A patent/SI9300589A/sl unknown
- 1993-11-12 LT LTIP1469A patent/LT3107B/lt not_active IP Right Cessation
-
1994
- 1994-07-26 MD MD94-0311A patent/MD937C2/ro active IP Right Grant
- 1994-11-18 EE EE9400145A patent/EE03135B1/xx unknown
-
1995
- 1995-05-10 FI FI952269A patent/FI952269A/fi unknown
- 1995-05-11 NO NO951864A patent/NO306760B1/no not_active IP Right Cessation
-
1997
- 1997-09-16 GR GR970402363T patent/GR3024720T3/el unknown
Also Published As
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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