EA201691401A1 - Индазольные соединения в качестве ингибиторов irak4 - Google Patents

Индазольные соединения в качестве ингибиторов irak4

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Publication number
EA201691401A1
EA201691401A1 EA201691401A EA201691401A EA201691401A1 EA 201691401 A1 EA201691401 A1 EA 201691401A1 EA 201691401 A EA201691401 A EA 201691401A EA 201691401 A EA201691401 A EA 201691401A EA 201691401 A1 EA201691401 A1 EA 201691401A1
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Eurasian Patent Office
Prior art keywords
indasolic
compounds
irak4
irak4 inhibitors
formula
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EA201691401A
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English (en)
Inventor
Венкатешвар Рао Гуммади
Сусанта Самадждар
Аджай Гупта
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Ориджин Дискавери Текнолоджиз Лимитед
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Application filed by Ориджин Дискавери Текнолоджиз Лимитед filed Critical Ориджин Дискавери Текнолоджиз Лимитед
Publication of EA201691401A1 publication Critical patent/EA201691401A1/ru

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Abstract

Настоящее изобретение относится к индазольному соединению формулы (I), которое является терапевтически полезным в качестве ингибитора киназы, в частности, ингибиторов IRAK4.где Z, Z, R, R, R, 'm' и 'n' имеют значения, указанные в описании, и его фармацевтически приемлемым солям или стереоизомерам, которые могут быть использованы для лечения и профилактики заболеваний или расстройств, в частности заболеваний или расстройств, опосредованных киназным ферментом, в частности ферментом IRAK4. Настоящее изобретение относится также к фармацевтической композиции, содержащей по меньшей мере одно соединение формулы (I) вместе с фармацевтически приемлемым носителем, разбавителем или вспомогательным веществом.
EA201691401A 2014-01-10 2015-01-07 Индазольные соединения в качестве ингибиторов irak4 EA201691401A1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IN146CH2014 2014-01-10
IN3018CH2014 2014-06-20
PCT/IB2015/050119 WO2015104662A1 (en) 2014-01-10 2015-01-07 Indazole compounds as irak4 inhibitors

Publications (1)

Publication Number Publication Date
EA201691401A1 true EA201691401A1 (ru) 2016-11-30

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ID=52462359

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EA201691401A EA201691401A1 (ru) 2014-01-10 2015-01-07 Индазольные соединения в качестве ингибиторов irak4

Country Status (16)

Country Link
US (1) US10160753B2 (ru)
EP (1) EP3092226B1 (ru)
JP (1) JP2017505337A (ru)
KR (1) KR20160115933A (ru)
CN (1) CN106458982A (ru)
AU (1) AU2015205348A1 (ru)
BR (1) BR112016015983A2 (ru)
CA (1) CA2935880A1 (ru)
CU (1) CU20160109A7 (ru)
EA (1) EA201691401A1 (ru)
HK (1) HK1231480A1 (ru)
IL (1) IL246555A0 (ru)
MX (1) MX2016009011A (ru)
PH (1) PH12016501338A1 (ru)
SG (1) SG11201605408RA (ru)
WO (1) WO2015104662A1 (ru)

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