EA201690213A1 - Композиции и способ лечения связанных с комплементом состояний - Google Patents

Композиции и способ лечения связанных с комплементом состояний

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Publication number
EA201690213A1
EA201690213A1 EA201690213A EA201690213A EA201690213A1 EA 201690213 A1 EA201690213 A1 EA 201690213A1 EA 201690213 A EA201690213 A EA 201690213A EA 201690213 A EA201690213 A EA 201690213A EA 201690213 A1 EA201690213 A1 EA 201690213A1
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EA
Eurasian Patent Office
Prior art keywords
treatment
compositions
factor
connected states
methods
Prior art date
Application number
EA201690213A
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English (en)
Inventor
Брайан Яспен
Роберт Ройял Грэхэм
Эми Дрессен
Чжэнрон Ли
Эрих Штраусс
Теодорика Бугаван
Original Assignee
Дженентек, Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Дженентек, Инк. filed Critical Дженентек, Инк.
Publication of EA201690213A1 publication Critical patent/EA201690213A1/ru

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/118—Prognosis of disease development
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

Abstract

Описаны способы и композиции для лечения различных дегенеративных заболеваний (например, ВМД) с ингибитором фактора D (например, антителом к фактору D или его антигенсвязывающим фрагментом). Также предусмотрены способы выбора или идентификации пациентов для лечения с ингибитором фактора D. Способы включают применение прогностических и/или предиктивных биомаркеров.
EA201690213A 2013-08-12 2014-08-11 Композиции и способ лечения связанных с комплементом состояний EA201690213A1 (ru)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US201361864941P 2013-08-12 2013-08-12
US201361866651P 2013-08-16 2013-08-16
US201361872098P 2013-08-30 2013-08-30
US201461988012P 2014-05-02 2014-05-02
US201462021487P 2014-07-07 2014-07-07
PCT/US2014/050579 WO2015023596A1 (en) 2013-08-12 2014-08-11 Compositions and method for treating complement-associated conditions

Publications (1)

Publication Number Publication Date
EA201690213A1 true EA201690213A1 (ru) 2016-07-29

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
EA201690213A EA201690213A1 (ru) 2013-08-12 2014-08-11 Композиции и способ лечения связанных с комплементом состояний

Country Status (18)

Country Link
US (3) US10093978B2 (ru)
EP (1) EP3033436A1 (ru)
JP (3) JP6463359B2 (ru)
KR (2) KR20180021234A (ru)
CN (1) CN107318267B (ru)
AU (1) AU2014306867B2 (ru)
BR (1) BR112016002845A2 (ru)
CA (1) CA2920666A1 (ru)
CL (1) CL2016000326A1 (ru)
CR (1) CR20160132A (ru)
EA (1) EA201690213A1 (ru)
IL (1) IL243928A0 (ru)
MX (1) MX2016001854A (ru)
PE (1) PE20160192A1 (ru)
PH (1) PH12016500302A1 (ru)
SG (1) SG11201601044XA (ru)
TW (1) TWI656217B (ru)
WO (1) WO2015023596A1 (ru)

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CN109448781B (zh) * 2018-11-06 2021-09-14 云南大学 一种流感病毒抗原变化的预测方法
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