MX2020010947A - Metodos de tratamiento de enfermedad de alzheimer. - Google Patents

Metodos de tratamiento de enfermedad de alzheimer.

Info

Publication number
MX2020010947A
MX2020010947A MX2020010947A MX2020010947A MX2020010947A MX 2020010947 A MX2020010947 A MX 2020010947A MX 2020010947 A MX2020010947 A MX 2020010947A MX 2020010947 A MX2020010947 A MX 2020010947A MX 2020010947 A MX2020010947 A MX 2020010947A
Authority
MX
Mexico
Prior art keywords
methods
disease
treating alzheimer
patients
mild
Prior art date
Application number
MX2020010947A
Other languages
English (en)
Inventor
Robert Graham
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of MX2020010947A publication Critical patent/MX2020010947A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

Abstract

Se proporcionan métodos de tratamiento de enfermedad de Alzheimer (AD) en pacientes que sufren de AD leve a moderada, incluyendo pacientes ApoE4 positivos y pacientes que sufren de AD leve. También se proporcionan métodos de selección o identificación de pacientes para el tratamiento con un anticuerpo anti-Abeta. Los métodos incluyen el uso de biomarcadores pronósticos y/o predictivos.
MX2020010947A 2014-02-08 2016-08-05 Metodos de tratamiento de enfermedad de alzheimer. MX2020010947A (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201461937472P 2014-02-08 2014-02-08
US201461971499P 2014-03-27 2014-03-27
US201462010265P 2014-06-10 2014-06-10
US201462082013P 2014-11-19 2014-11-19

Publications (1)

Publication Number Publication Date
MX2020010947A true MX2020010947A (es) 2020-11-09

Family

ID=52574436

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2016010237A MX2016010237A (es) 2014-02-08 2015-02-06 Metodos de tratamiento de enfermedad de alzheimer.
MX2020010947A MX2020010947A (es) 2014-02-08 2016-08-05 Metodos de tratamiento de enfermedad de alzheimer.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
MX2016010237A MX2016010237A (es) 2014-02-08 2015-02-06 Metodos de tratamiento de enfermedad de alzheimer.

Country Status (16)

Country Link
US (2) US20170369559A9 (es)
EP (2) EP3102230B1 (es)
JP (3) JP6702878B2 (es)
KR (1) KR102476641B1 (es)
CN (2) CN112826930A (es)
AU (2) AU2015213741B2 (es)
BR (1) BR112016018205A8 (es)
CA (1) CA2938731A1 (es)
ES (1) ES2873248T3 (es)
IL (1) IL247085B (es)
MX (2) MX2016010237A (es)
PL (1) PL3102230T3 (es)
RU (2) RU2720468C2 (es)
SG (2) SG11201606490YA (es)
TW (3) TWI785472B (es)
WO (1) WO2015120280A1 (es)

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WO2017193046A1 (en) 2016-05-06 2017-11-09 Sage Therapeutics, Inc. Oxysterols and methods of use thereof
TWI735600B (zh) 2016-07-01 2021-08-11 美商美國禮來大藥廠 抗－N3pGlu類澱粉β肽抗體及其用途
WO2018023036A1 (en) * 2016-07-29 2018-02-01 Biogen Chesapeake Llc Methods of treating or preventing amyloid related imaging abnormalities associated with alzheimer's disease treatment
JP2019020206A (ja) * 2017-07-14 2019-02-07 株式会社島津製作所 質量分析を用いた認知機能障害疾患バイオマーカーの定量方法及び質量分析装置
US11058729B2 (en) * 2018-01-25 2021-07-13 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Exosomes and miRNA to treat glaucoma
KR102555878B1 (ko) * 2020-04-23 2023-07-17 주식회사 바이오오케스트라 하향조절된 mirna의 진단 및 치료를 위한 용도
JP2023535024A (ja) 2020-07-23 2023-08-15 オター プロシーナ リミテッド 抗ａベータ抗体
JP2023550242A (ja) * 2020-11-19 2023-12-01 リジェネロン・ファーマシューティカルズ・インコーポレイテッド シーケンシングによるジェノタイピング
KR20240035444A (ko) * 2021-06-11 2024-03-15 세이지 테라퓨틱스, 인크. 알츠하이머병 치료를 위한 신경활성 스테로이드
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JP2017507130A (ja) 2017-03-16
MX2016010237A (es) 2017-04-27
RU2020111676A (ru) 2020-06-10
JP2020090497A (ja) 2020-06-11
TWI785472B (zh) 2022-12-01
BR112016018205A2 (pt) 2017-10-10
IL247085A0 (en) 2016-09-29
RU2016132162A3 (es) 2018-11-20
TW202239429A (zh) 2022-10-16
JP2022036946A (ja) 2022-03-08
IL247085B (en) 2020-10-29
EP3102230A1 (en) 2016-12-14
TWI769970B (zh) 2022-07-11
AU2020233696A1 (en) 2020-10-08
US20170369559A9 (en) 2017-12-28
EP3102230B1 (en) 2021-04-28
SG10201901076WA (en) 2019-03-28
CN112826930A (zh) 2021-05-25
AU2015213741B2 (en) 2020-10-08
CA2938731A1 (en) 2015-08-13
JP6702878B2 (ja) 2020-06-03
ES2873248T3 (es) 2021-11-03
RU2720468C2 (ru) 2020-04-30
AU2015213741A1 (en) 2016-08-25
BR112016018205A8 (pt) 2018-04-17
KR20160113722A (ko) 2016-09-30
SG11201606490YA (en) 2016-09-29
CN106456729A (zh) 2017-02-22
EP3900738A1 (en) 2021-10-27
KR102476641B1 (ko) 2022-12-09
TW201613637A (en) 2016-04-16
TW202140070A (zh) 2021-11-01
RU2016132162A (ru) 2018-03-14
US20170198030A1 (en) 2017-07-13
PL3102230T3 (pl) 2021-11-15
WO2015120280A1 (en) 2015-08-13
US20220098288A1 (en) 2022-03-31

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