EA200300663A1 - Антагонисты cxcr3 - Google Patents

Антагонисты cxcr3

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Publication number
EA200300663A1
EA200300663A1 EA200300663A EA200300663A EA200300663A1 EA 200300663 A1 EA200300663 A1 EA 200300663A1 EA 200300663 A EA200300663 A EA 200300663A EA 200300663 A EA200300663 A EA 200300663A EA 200300663 A1 EA200300663 A1 EA 200300663A1
Authority
EA
Eurasian Patent Office
Prior art keywords
inflammatory
diseases
applicable
treatment
compounds
Prior art date
Application number
EA200300663A
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English (en)
Other versions
EA007538B1 (ru
Inventor
Джулио К. Медина
Майкл Дж. Джонсон
Ан-Ронг Ли
Дживен Лиу
Алан Кси Хуанг
Лиушенг Жу
Эндрю П. Маркус
Original Assignee
Туларик Инк.
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Application filed by Туларик Инк. filed Critical Туларик Инк.
Publication of EA200300663A1 publication Critical patent/EA200300663A1/ru
Publication of EA007538B1 publication Critical patent/EA007538B1/ru

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    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
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    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
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Abstract

Предложены соединения, композиции и способы, которые применимы при лечении воспалительных и иммунных состояний и заболеваний. В частности, изобретение относится к соединениям, которые модулируют экспрессию и/или функцию рецептора хемокина. Предложенные способы применимы для лечения воспалительных и иммунорегуляторных расстройств и заболеваний, таких как рассеянный склероз, ревматоидный артрит и диабет типа I.Международная заявка была опубликована вместе с отчетом о международном поиске.
EA200300663A 2000-12-11 2001-12-11 Антагонисты cxcr3 EA007538B1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US25524100P 2000-12-11 2000-12-11
US29649901P 2001-06-06 2001-06-06
PCT/US2001/047850 WO2002083143A1 (en) 2000-12-11 2001-12-11 Cxcr3 antagonists

Publications (2)

Publication Number Publication Date
EA200300663A1 true EA200300663A1 (ru) 2004-06-24
EA007538B1 EA007538B1 (ru) 2006-10-27

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EA200300663A EA007538B1 (ru) 2000-12-11 2001-12-11 Антагонисты cxcr3

Country Status (19)

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US (3) US6964967B2 (ru)
EP (1) EP1343505A1 (ru)
JP (1) JP4259877B2 (ru)
KR (1) KR100883184B1 (ru)
CN (1) CN1575177A (ru)
AU (1) AU2001297717B2 (ru)
BR (1) BR0116096A (ru)
CA (1) CA2431553A1 (ru)
CZ (1) CZ20031910A3 (ru)
EA (1) EA007538B1 (ru)
HU (1) HUP0500880A2 (ru)
IL (2) IL156304A0 (ru)
MX (1) MXPA03005152A (ru)
NO (1) NO325450B1 (ru)
NZ (1) NZ526622A (ru)
PL (1) PL366311A1 (ru)
SK (1) SK8752003A3 (ru)
WO (1) WO2002083143A1 (ru)
ZA (1) ZA200304342B (ru)

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