EA200200656A1 - НОВЫЕ ТЕРАПЕВТИЧЕСКИЕ КОМБИНАЦИИ (S)-2-(БЕНЗИЛАМИНОМЕТИЛ)-2,3,8,9-ТЕТРАГИДРО-7H-1,4-ДИОКСИН [2,3-е]ИНДОЛ-8-ОНА И НЕЙРОЛЕПТИКОВ ДЛЯ ЛЕЧЕНИЯ ИЛИ ПРЕДОТВРАЩЕНИЯ ПСИХОТИЧЕСКИХ РАССТРОЙСТВ - Google Patents

НОВЫЕ ТЕРАПЕВТИЧЕСКИЕ КОМБИНАЦИИ (S)-2-(БЕНЗИЛАМИНОМЕТИЛ)-2,3,8,9-ТЕТРАГИДРО-7H-1,4-ДИОКСИН [2,3-е]ИНДОЛ-8-ОНА И НЕЙРОЛЕПТИКОВ ДЛЯ ЛЕЧЕНИЯ ИЛИ ПРЕДОТВРАЩЕНИЯ ПСИХОТИЧЕСКИХ РАССТРОЙСТВ

Info

Publication number
EA200200656A1
EA200200656A1 EA200200656A EA200200656A EA200200656A1 EA 200200656 A1 EA200200656 A1 EA 200200656A1 EA 200200656 A EA200200656 A EA 200200656A EA 200200656 A EA200200656 A EA 200200656A EA 200200656 A1 EA200200656 A1 EA 200200656A1
Authority
EA
Eurasian Patent Office
Prior art keywords
benzylaminometyl
neuroleptic
dioxin
indol
psychological
Prior art date
Application number
EA200200656A
Other languages
English (en)
Other versions
EA005002B1 (ru
Inventor
Карен Лавелл Марквис
Original Assignee
Уайт
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Уайт filed Critical Уайт
Publication of EA200200656A1 publication Critical patent/EA200200656A1/ru
Publication of EA005002B1 publication Critical patent/EA005002B1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A61K31/4045—Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Abstract

Предоставляются терапевтические комбинации, которые можно применять при лечении или предотвращении психотических расстройств, фармацевтические композиции, содержащие указанные комбинации, и их применение при лечении или предотвращении психотических расстройств.Отчет о международном поиске был опубликован 2002.02.14.
EA200200656A 1999-12-10 2000-12-07 НОВЫЕ ТЕРАПЕВТИЧЕСКИЕ КОМБИНАЦИИ (S)-2-(БЕНЗИЛАМИНОМЕТИЛ)-2,3,8,9-ТЕТРАГИДРО-7H-1,4-ДИОКСИН [2,3-e]ИНДОЛ-8-ОНА И НЕЙРОЛЕПТИКОВ ДЛЯ ЛЕЧЕНИЯ ИЛИ ПРЕДОТВРАЩЕНИЯ ПСИХОТИЧЕСКИХ РАССТРОЙСТВ EA005002B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US45860799A 1999-12-10 1999-12-10
PCT/US2000/033060 WO2001041750A2 (en) 1999-12-10 2000-12-07 Combinations of (s)-2-(benzylamino-methyl)-2,3,8,9,-tetrahydro-7h-1,4-dioxino(2,3)-e indol-8-one and neuroleptics

Publications (2)

Publication Number Publication Date
EA200200656A1 true EA200200656A1 (ru) 2002-12-26
EA005002B1 EA005002B1 (ru) 2004-10-28

Family

ID=23821437

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200200656A EA005002B1 (ru) 1999-12-10 2000-12-07 НОВЫЕ ТЕРАПЕВТИЧЕСКИЕ КОМБИНАЦИИ (S)-2-(БЕНЗИЛАМИНОМЕТИЛ)-2,3,8,9-ТЕТРАГИДРО-7H-1,4-ДИОКСИН [2,3-e]ИНДОЛ-8-ОНА И НЕЙРОЛЕПТИКОВ ДЛЯ ЛЕЧЕНИЯ ИЛИ ПРЕДОТВРАЩЕНИЯ ПСИХОТИЧЕСКИХ РАССТРОЙСТВ

Country Status (20)

Country Link
EP (1) EP1235570A2 (ru)
JP (1) JP5557409B2 (ru)
KR (1) KR100772854B1 (ru)
CN (1) CN1230164C (ru)
AR (1) AR026756A1 (ru)
AU (1) AU784211B2 (ru)
BR (1) BR0016168A (ru)
CA (1) CA2396351C (ru)
CZ (1) CZ20021880A3 (ru)
EA (1) EA005002B1 (ru)
HK (1) HK1045942A1 (ru)
HU (1) HUP0203309A3 (ru)
IL (2) IL149669A0 (ru)
MX (1) MXPA02005649A (ru)
NO (1) NO20022739L (ru)
NZ (1) NZ519381A (ru)
PL (1) PL355292A1 (ru)
TW (1) TWI222864B (ru)
WO (1) WO2001041750A2 (ru)
ZA (1) ZA200205484B (ru)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2376988C2 (ru) 2003-10-29 2009-12-27 Уайт Фармацевтические композиции замедленного высвобождения, содержащие аплиндор и его производные
BRPI0608353A2 (pt) 2005-02-17 2009-12-01 Wyeth Corp derivados de indol, benzotiofeno, benzofurano e indeno cicloalquilfundidos
WO2009102962A2 (en) * 2008-02-13 2009-08-20 Targacept, Inc. Combination of alpha 7 nicotinic agonists and antipsychotics

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2987484B2 (ja) * 1995-03-16 1999-12-06 大塚製薬 株式会社 カルボスチリル誘導体の製造方法
US5756532A (en) * 1995-11-06 1998-05-26 American Home Products Corporation Aminomethyl-2 3 8 9-tetrahydro-7H-1 4-dioxino 2 3-E!-indol-8-ones and derivatives
GB9627005D0 (en) * 1996-12-27 1997-02-12 Knoll Ag Therapeutic agents

Also Published As

Publication number Publication date
MXPA02005649A (es) 2004-09-10
JP2003516350A (ja) 2003-05-13
WO2001041750A3 (en) 2002-02-14
NZ519381A (en) 2004-04-30
HUP0203309A2 (hu) 2003-01-28
IL149669A (en) 2006-06-11
CN1409633A (zh) 2003-04-09
AU784211B2 (en) 2006-02-23
CA2396351C (en) 2009-11-10
CA2396351A1 (en) 2001-06-14
CZ20021880A3 (cs) 2002-08-14
CN1230164C (zh) 2005-12-07
EA005002B1 (ru) 2004-10-28
PL355292A1 (en) 2004-04-05
EP1235570A2 (en) 2002-09-04
NO20022739D0 (no) 2002-06-07
AR026756A1 (es) 2003-02-26
TWI222864B (en) 2004-11-01
AU1949001A (en) 2001-06-18
KR100772854B1 (ko) 2007-11-02
KR20030016207A (ko) 2003-02-26
HUP0203309A3 (en) 2004-12-28
HK1045942A1 (zh) 2002-12-20
ZA200205484B (en) 2003-12-31
BR0016168A (pt) 2002-08-20
NO20022739L (no) 2002-06-07
JP5557409B2 (ja) 2014-07-23
WO2001041750A2 (en) 2001-06-14
IL149669A0 (en) 2002-11-10

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Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG MD TJ TM

MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): RU