MXPA02005649A - Nuevas combinaciones terapeuticas de (s)-2 -(bencilamino -metil)-2, 3, 8, 9-tetrahidro-7h -1, 4-dioxino(2-3 -e]indol-8 -ona y agentes neurolepticos para el tratamiento o prevencion de trastornos psicoticos. - Google Patents

Nuevas combinaciones terapeuticas de (s)-2 -(bencilamino -metil)-2, 3, 8, 9-tetrahidro-7h -1, 4-dioxino(2-3 -e]indol-8 -ona y agentes neurolepticos para el tratamiento o prevencion de trastornos psicoticos.

Info

Publication number
MXPA02005649A
MXPA02005649A MXPA02005649A MXPA02005649A MXPA02005649A MX PA02005649 A MXPA02005649 A MX PA02005649A MX PA02005649 A MXPA02005649 A MX PA02005649A MX PA02005649 A MXPA02005649 A MX PA02005649A MX PA02005649 A MXPA02005649 A MX PA02005649A
Authority
MX
Mexico
Prior art keywords
combinations
dioxino
neuroleptics
benzylamino
indol
Prior art date
Application number
MXPA02005649A
Other languages
English (en)
Inventor
Lovell Marquis Karen
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Corp filed Critical Wyeth Corp
Publication of MXPA02005649A publication Critical patent/MXPA02005649A/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404Indoles, e.g. pindolol
    • A61K31/4045Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/407Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Abstract

La invencion se refiere a combinaciones farmaceuticas utiles en el tratamiento o prevencion de trastornos psicoticos, a composiciones farmaceuticas que las contienen, y a su uso en el tratamiento o profilaxis de trastornos psicoticos.
MXPA02005649A 1999-12-10 2000-12-07 Nuevas combinaciones terapeuticas de (s)-2 -(bencilamino -metil)-2, 3, 8, 9-tetrahidro-7h -1, 4-dioxino(2-3 -e]indol-8 -ona y agentes neurolepticos para el tratamiento o prevencion de trastornos psicoticos. MXPA02005649A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US45860799A 1999-12-10 1999-12-10
PCT/US2000/033060 WO2001041750A2 (en) 1999-12-10 2000-12-07 Combinations of (s)-2-(benzylamino-methyl)-2,3,8,9,-tetrahydro-7h-1,4-dioxino(2,3)-e indol-8-one and neuroleptics

Publications (1)

Publication Number Publication Date
MXPA02005649A true MXPA02005649A (es) 2004-09-10

Family

ID=23821437

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA02005649A MXPA02005649A (es) 1999-12-10 2000-12-07 Nuevas combinaciones terapeuticas de (s)-2 -(bencilamino -metil)-2, 3, 8, 9-tetrahidro-7h -1, 4-dioxino(2-3 -e]indol-8 -ona y agentes neurolepticos para el tratamiento o prevencion de trastornos psicoticos.

Country Status (20)

Country Link
EP (1) EP1235570A2 (es)
JP (1) JP5557409B2 (es)
KR (1) KR100772854B1 (es)
CN (1) CN1230164C (es)
AR (1) AR026756A1 (es)
AU (1) AU784211B2 (es)
BR (1) BR0016168A (es)
CA (1) CA2396351C (es)
CZ (1) CZ20021880A3 (es)
EA (1) EA005002B1 (es)
HK (1) HK1045942A1 (es)
HU (1) HUP0203309A3 (es)
IL (2) IL149669A0 (es)
MX (1) MXPA02005649A (es)
NO (1) NO20022739L (es)
NZ (1) NZ519381A (es)
PL (1) PL355292A1 (es)
TW (1) TWI222864B (es)
WO (1) WO2001041750A2 (es)
ZA (1) ZA200205484B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1874767A (zh) 2003-10-29 2006-12-06 惠氏公司 包含aplindore和其衍生物的缓释药物组合物
WO2006089053A2 (en) 2005-02-17 2006-08-24 Wyeth Cycloalkylfused indole, benzothiophene, benzofuran and indene derivatives
US20110059947A1 (en) * 2008-02-13 2011-03-10 Targacept, Inc. Alpha 7 nicotinic agonists and antipsychotics

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2987484B2 (ja) * 1995-03-16 1999-12-06 大塚製薬 株式会社 カルボスチリル誘導体の製造方法
US5756532A (en) * 1995-11-06 1998-05-26 American Home Products Corporation Aminomethyl-2 3 8 9-tetrahydro-7H-1 4-dioxino 2 3-E!-indol-8-ones and derivatives
GB9627005D0 (en) * 1996-12-27 1997-02-12 Knoll Ag Therapeutic agents

Also Published As

Publication number Publication date
CZ20021880A3 (cs) 2002-08-14
IL149669A (en) 2006-06-11
PL355292A1 (en) 2004-04-05
JP5557409B2 (ja) 2014-07-23
NO20022739D0 (no) 2002-06-07
EP1235570A2 (en) 2002-09-04
IL149669A0 (en) 2002-11-10
NZ519381A (en) 2004-04-30
ZA200205484B (en) 2003-12-31
AU784211B2 (en) 2006-02-23
CA2396351C (en) 2009-11-10
KR20030016207A (ko) 2003-02-26
WO2001041750A3 (en) 2002-02-14
EA200200656A1 (ru) 2002-12-26
CN1409633A (zh) 2003-04-09
TWI222864B (en) 2004-11-01
WO2001041750A2 (en) 2001-06-14
CA2396351A1 (en) 2001-06-14
HUP0203309A3 (en) 2004-12-28
CN1230164C (zh) 2005-12-07
HK1045942A1 (zh) 2002-12-20
AU1949001A (en) 2001-06-18
HUP0203309A2 (hu) 2003-01-28
NO20022739L (no) 2002-06-07
AR026756A1 (es) 2003-02-26
BR0016168A (pt) 2002-08-20
JP2003516350A (ja) 2003-05-13
KR100772854B1 (ko) 2007-11-02
EA005002B1 (ru) 2004-10-28

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