IL149669A0 - NEW THERAPEUTIC COMBINATIONS OF (S) -2-(BENZYLAMINO-METHYL)-2,3,8,9-TETRAHYDRO-7H-1,4-DIOXINO[2,3-e] INDOL-8-ONE AND NEUROLEPTICS FOR THE TREATMENT OR PREVENTION OF PSYCHOTIC DISORDERS - Google Patents

NEW THERAPEUTIC COMBINATIONS OF (S) -2-(BENZYLAMINO-METHYL)-2,3,8,9-TETRAHYDRO-7H-1,4-DIOXINO[2,3-e] INDOL-8-ONE AND NEUROLEPTICS FOR THE TREATMENT OR PREVENTION OF PSYCHOTIC DISORDERS

Info

Publication number
IL149669A0
IL149669A0 IL14966900A IL14966900A IL149669A0 IL 149669 A0 IL149669 A0 IL 149669A0 IL 14966900 A IL14966900 A IL 14966900A IL 14966900 A IL14966900 A IL 14966900A IL 149669 A0 IL149669 A0 IL 149669A0
Authority
IL
Israel
Prior art keywords
dioxino
neuroleptics
benzylamino
indol
tetrahydro
Prior art date
Application number
IL14966900A
Other languages
English (en)
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Corp filed Critical Wyeth Corp
Publication of IL149669A0 publication Critical patent/IL149669A0/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A61K31/4045—Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
IL14966900A 1999-12-10 2000-12-07 NEW THERAPEUTIC COMBINATIONS OF (S) -2-(BENZYLAMINO-METHYL)-2,3,8,9-TETRAHYDRO-7H-1,4-DIOXINO[2,3-e] INDOL-8-ONE AND NEUROLEPTICS FOR THE TREATMENT OR PREVENTION OF PSYCHOTIC DISORDERS IL149669A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US45860799A 1999-12-10 1999-12-10
PCT/US2000/033060 WO2001041750A2 (en) 1999-12-10 2000-12-07 Combinations of (s)-2-(benzylamino-methyl)-2,3,8,9,-tetrahydro-7h-1,4-dioxino(2,3)-e indol-8-one and neuroleptics

Publications (1)

Publication Number Publication Date
IL149669A0 true IL149669A0 (en) 2002-11-10

Family

ID=23821437

Family Applications (2)

Application Number Title Priority Date Filing Date
IL14966900A IL149669A0 (en) 1999-12-10 2000-12-07 NEW THERAPEUTIC COMBINATIONS OF (S) -2-(BENZYLAMINO-METHYL)-2,3,8,9-TETRAHYDRO-7H-1,4-DIOXINO[2,3-e] INDOL-8-ONE AND NEUROLEPTICS FOR THE TREATMENT OR PREVENTION OF PSYCHOTIC DISORDERS
IL149669A IL149669A (en) 1999-12-10 2002-05-15 Combinations of (S) - 2) Benzylamino – methyl) 2,9,8,3,2 –– Tetrahydro-H7–1, 4 – Dioxino] E – 3,2 [Indole-8 – on and neuroleptic for the treatment or prevention of Psychotic arrangements

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL149669A IL149669A (en) 1999-12-10 2002-05-15 Combinations of (S) - 2) Benzylamino – methyl) 2,9,8,3,2 –– Tetrahydro-H7–1, 4 – Dioxino] E – 3,2 [Indole-8 – on and neuroleptic for the treatment or prevention of Psychotic arrangements

Country Status (20)

Country Link
EP (1) EP1235570A2 (xx)
JP (1) JP5557409B2 (xx)
KR (1) KR100772854B1 (xx)
CN (1) CN1230164C (xx)
AR (1) AR026756A1 (xx)
AU (1) AU784211B2 (xx)
BR (1) BR0016168A (xx)
CA (1) CA2396351C (xx)
CZ (1) CZ20021880A3 (xx)
EA (1) EA005002B1 (xx)
HK (1) HK1045942A1 (xx)
HU (1) HUP0203309A3 (xx)
IL (2) IL149669A0 (xx)
MX (1) MXPA02005649A (xx)
NO (1) NO20022739L (xx)
NZ (1) NZ519381A (xx)
PL (1) PL355292A1 (xx)
TW (1) TWI222864B (xx)
WO (1) WO2001041750A2 (xx)
ZA (1) ZA200205484B (xx)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1874767A (zh) 2003-10-29 2006-12-06 惠氏公司 包含aplindore和其衍生物的缓释药物组合物
WO2006089053A2 (en) 2005-02-17 2006-08-24 Wyeth Cycloalkylfused indole, benzothiophene, benzofuran and indene derivatives
US20110059947A1 (en) * 2008-02-13 2011-03-10 Targacept, Inc. Alpha 7 nicotinic agonists and antipsychotics

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2987484B2 (ja) * 1995-03-16 1999-12-06 大塚製薬 株式会社 カルボスチリル誘導体の製造方法
US5756532A (en) * 1995-11-06 1998-05-26 American Home Products Corporation Aminomethyl-2 3 8 9-tetrahydro-7H-1 4-dioxino 2 3-E!-indol-8-ones and derivatives
GB9627005D0 (en) * 1996-12-27 1997-02-12 Knoll Ag Therapeutic agents

Also Published As

Publication number Publication date
CZ20021880A3 (cs) 2002-08-14
IL149669A (en) 2006-06-11
PL355292A1 (en) 2004-04-05
JP5557409B2 (ja) 2014-07-23
NO20022739D0 (no) 2002-06-07
EP1235570A2 (en) 2002-09-04
NZ519381A (en) 2004-04-30
ZA200205484B (en) 2003-12-31
AU784211B2 (en) 2006-02-23
CA2396351C (en) 2009-11-10
KR20030016207A (ko) 2003-02-26
WO2001041750A3 (en) 2002-02-14
EA200200656A1 (ru) 2002-12-26
CN1409633A (zh) 2003-04-09
TWI222864B (en) 2004-11-01
WO2001041750A2 (en) 2001-06-14
MXPA02005649A (es) 2004-09-10
CA2396351A1 (en) 2001-06-14
HUP0203309A3 (en) 2004-12-28
CN1230164C (zh) 2005-12-07
HK1045942A1 (zh) 2002-12-20
AU1949001A (en) 2001-06-18
HUP0203309A2 (hu) 2003-01-28
NO20022739L (no) 2002-06-07
AR026756A1 (es) 2003-02-26
BR0016168A (pt) 2002-08-20
JP2003516350A (ja) 2003-05-13
KR100772854B1 (ko) 2007-11-02
EA005002B1 (ru) 2004-10-28

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KB Patent renewed