DZ2440A1 - Atropisomères de 3-aryl-4(3h)-quinazolinones procédé pour leur préparation et compositions les contenant. - Google Patents
Atropisomères de 3-aryl-4(3h)-quinazolinones procédé pour leur préparation et compositions les contenant.Info
- Publication number
- DZ2440A1 DZ2440A1 DZ980050A DZ980050A DZ2440A1 DZ 2440 A1 DZ2440 A1 DZ 2440A1 DZ 980050 A DZ980050 A DZ 980050A DZ 980050 A DZ980050 A DZ 980050A DZ 2440 A1 DZ2440 A1 DZ 2440A1
- Authority
- DZ
- Algeria
- Prior art keywords
- quinazolinones
- atropisomers
- aryl
- preparation
- compositions containing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
- C07D239/88—Oxygen atoms
- C07D239/91—Oxygen atoms with aryl or aralkyl radicals attached in position 2 or 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US3890597P | 1997-02-28 | 1997-02-28 |
Publications (1)
Publication Number | Publication Date |
---|---|
DZ2440A1 true DZ2440A1 (fr) | 2003-01-11 |
Family
ID=21902563
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DZ980050A DZ2440A1 (fr) | 1997-02-28 | 1998-02-25 | Atropisomères de 3-aryl-4(3h)-quinazolinones procédé pour leur préparation et compositions les contenant. |
Country Status (40)
Country | Link |
---|---|
US (1) | US6306864B1 (fr) |
EP (1) | EP0968194B1 (fr) |
JP (1) | JP2000509731A (fr) |
KR (1) | KR100358636B1 (fr) |
CN (1) | CN1248248A (fr) |
AP (1) | AP859A (fr) |
AR (1) | AR011170A1 (fr) |
AT (1) | ATE267817T1 (fr) |
AU (1) | AU744028B2 (fr) |
BG (1) | BG103689A (fr) |
BR (1) | BR9807872A (fr) |
CA (1) | CA2282277C (fr) |
DE (1) | DE69824157T2 (fr) |
DK (1) | DK0968194T3 (fr) |
DZ (1) | DZ2440A1 (fr) |
EA (1) | EA001963B1 (fr) |
ES (1) | ES2219866T3 (fr) |
GT (1) | GT199800038A (fr) |
HR (1) | HRP980106A2 (fr) |
HU (1) | HUP0000914A3 (fr) |
ID (1) | ID22711A (fr) |
IL (1) | IL130900A0 (fr) |
IS (1) | IS1952B (fr) |
MA (1) | MA24484A1 (fr) |
NO (1) | NO313630B1 (fr) |
NZ (1) | NZ336628A (fr) |
OA (1) | OA11089A (fr) |
PA (1) | PA8447001A1 (fr) |
PE (1) | PE58399A1 (fr) |
PL (1) | PL335418A1 (fr) |
PT (1) | PT968194E (fr) |
SK (1) | SK113299A3 (fr) |
TN (1) | TNSN98035A1 (fr) |
TR (1) | TR199902093T2 (fr) |
TW (1) | TW504508B (fr) |
UA (1) | UA61097C2 (fr) |
UY (1) | UY24897A1 (fr) |
WO (1) | WO1998038173A1 (fr) |
YU (1) | YU41299A (fr) |
ZA (1) | ZA981666B (fr) |
Families Citing this family (33)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PL330042A1 (en) | 1996-05-15 | 1999-04-26 | Pfizer | Novel 2,3-disubstituted 4(3h)-quinazolynones |
US6323208B1 (en) | 1997-09-05 | 2001-11-27 | Pfizer Inc | Atropisomers of 2,3-disubstituted-(5.6)-heteroaryl fused-pyrimidin-4-ones |
JPH11279158A (ja) * | 1998-02-09 | 1999-10-12 | Pfizer Prod Inc | キナゾリン―4―オン誘導体の製造方法 |
US6667300B2 (en) | 2000-04-25 | 2003-12-23 | Icos Corporation | Inhibitors of human phosphatidylinositol 3-kinase delta |
ES2527754T3 (es) * | 2000-04-25 | 2015-01-29 | Icos Corporation | Inhibidores de la isoforma delta de la fosfatidilinositol 3-quinasa humana |
EP2053041A3 (fr) | 2000-06-12 | 2009-07-29 | Eisai R&D Management Co., Ltd. | 2(1H)-Pyridones 1,3,5-trisubstituées commes inhibiteurs du récepteur AMPA utilisables pour le traitement par ex. de la maladie de Parkinson |
ATE497385T1 (de) | 2000-08-18 | 2011-02-15 | Ajinomoto Kk | Neue phenylalanin-derivate |
GB0129260D0 (en) | 2001-12-06 | 2002-01-23 | Eisai London Res Lab Ltd | Pharmaceutical compositions and their uses |
US6939968B2 (en) * | 2002-12-23 | 2005-09-06 | Bristol-Myers Squibb Company | Atropisomers of 3-substituted-4-arylquinolin-2-one derivatives |
AU2004262533A1 (en) * | 2003-08-08 | 2005-02-17 | Ulysses Pharmaceutical Products Inc. | Halogenated quinazolinyl nitrofurans as antibacterial agents |
US20080146562A1 (en) * | 2003-08-08 | 2008-06-19 | Ulysses Pharmaceutical Products Inc., | Halogenated quinazolinyl nitrofurans as antibacterial agents |
GB0325390D0 (en) * | 2003-10-30 | 2003-12-03 | Novartis Ag | Organic compounds |
AU2004303696B2 (en) | 2003-12-22 | 2011-03-31 | Ea Pharma Co., Ltd. | Novel phenylalanine derivative |
PL3153514T3 (pl) | 2004-05-13 | 2022-01-10 | Icos Corporation | Chinazolinony jako inhibitory ludzkiej 3-kinazy fosfatydyloinozytolowej delta |
MY148809A (en) | 2004-07-06 | 2013-05-31 | Eisai R&D Man Co Ltd | Crystals of 1,2-dihydropyridine compound and their production process |
GB0416730D0 (en) * | 2004-07-27 | 2004-09-01 | Novartis Ag | Organic compounds |
JP2009514954A (ja) | 2005-11-04 | 2009-04-09 | ハイドラ バイオサイエンシズ インコーポレイテッド | Trpv3機能を変調するための化合物 |
CA2663436A1 (fr) | 2006-10-04 | 2008-04-10 | Pfizer Products Inc. | Derives de pyrido[4,3-d]pyrimidin-4(3h)-one utilises en tant qu'antagonistes du recepteur calcique |
WO2008140750A1 (fr) | 2007-05-10 | 2008-11-20 | Hydra Biosciences Inc. | Composés modulant la fonction du trp v3 |
CN101429166B (zh) * | 2007-11-07 | 2013-08-21 | 上海特化医药科技有限公司 | 喹唑啉酮衍生物及其制备方法和用途 |
US9492449B2 (en) | 2008-11-13 | 2016-11-15 | Gilead Calistoga Llc | Therapies for hematologic malignancies |
CN102271683B (zh) | 2008-11-13 | 2014-07-09 | 吉里德卡利斯托加公司 | 恶性血液病的治疗 |
EA019499B1 (ru) | 2009-03-24 | 2014-04-30 | ГИЛИЭД КАЛИСТОГА ЭлЭлСи | Производные атропоизомеров 2-пуринил-3-толилхиназолинона и способы применения |
MX2012000817A (es) | 2009-07-21 | 2012-05-08 | Gilead Calistoga Llc | Tratamiento para desordenes del higado con inhibidores pi3k. |
AP2014007875A0 (en) | 2012-03-05 | 2014-08-31 | Gilead Calistoga Llc | Polymorphic forms of (S)-2-(1-(9H-purin-6-ylamino)propyl)-5-fluoro-3-phenylquinazolin-4(3H)-one |
CN103275086B (zh) * | 2013-05-30 | 2015-04-15 | 温州大学 | 一种6-取代喹唑啉并喹唑啉酮化合物及其合成方法和用途 |
CN105849108A (zh) | 2013-12-20 | 2016-08-10 | 吉利德卡利斯托加公司 | 磷脂酰肌醇3-激酶抑制剂的制备方法 |
WO2015095605A1 (fr) | 2013-12-20 | 2015-06-25 | Gilead Calistoga Llc | Formes polymorphes d'un sel chlorhydrate de la (s)-2-(9h-purine-6-ylamino)propyl)-5-fluoro-3-phénylquinazolin-4(3h)-one |
US9533909B2 (en) | 2014-03-31 | 2017-01-03 | Corning Incorporated | Methods and apparatus for material processing using atmospheric thermal plasma reactor |
MA40059A (fr) | 2014-06-13 | 2015-12-17 | Gilead Sciences Inc | Inhibiteurs de la phosphatidylinositol 3-kinase |
DE102014217021A1 (de) * | 2014-08-27 | 2016-03-03 | Skf Lubrication Systems Germany Ag | Gehäuse für eine Vorrichtung zum dosierten Verteilen eines Mediums sowie eine Dosiereinrichtung zur Verwendung in dem Gehäuse |
BR112021010953A2 (pt) | 2018-12-14 | 2021-08-24 | Eisai R&D Management Co., Ltd. | Formulações farmacêuticas de base aquosa de compostos de 1,2-di-hidropiridina |
US11807621B2 (en) | 2020-01-29 | 2023-11-07 | Kamari Pharma Ltd. | Compounds and compositions for use in treating skin disorders |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1195321B (de) * | 1962-03-16 | 1965-06-24 | Troponwerke Dinklage & Co | Verfahren zur Herstellung von substituierten Chinazolon-(4)-derivaten |
DE1670416A1 (de) * | 1966-12-30 | 1971-02-11 | Chem Fab Von Heyden Gmbh Muenc | Verfahren zur Herstellung von aminosubstituierten Chinazolinonderivaten |
GB1298603A (en) * | 1970-04-06 | 1972-12-06 | Karamchand Premchand Private | Quinazolinone derivatives |
US4183931A (en) * | 1977-09-08 | 1980-01-15 | Research Corporation | 2-Ketoalkyl-4(3H)-quinazolinones |
GB9022785D0 (en) * | 1990-10-19 | 1990-12-05 | Merck Sharp & Dohme | Therapeutic agents |
WO1992013535A1 (fr) * | 1991-02-06 | 1992-08-20 | Research Corporation Technologies, Inc. | Quinazolones substituees a activite anticonvulsivante |
US5777271A (en) * | 1996-01-18 | 1998-07-07 | Commscope, Inc. | Cable having an at least partially oxidized armor layer |
PL330042A1 (en) * | 1996-05-15 | 1999-04-26 | Pfizer | Novel 2,3-disubstituted 4(3h)-quinazolynones |
-
1998
- 1998-02-06 ID IDW990937A patent/ID22711A/id unknown
- 1998-02-06 US US09/367,960 patent/US6306864B1/en not_active Expired - Fee Related
- 1998-02-06 EP EP98900978A patent/EP0968194B1/fr not_active Expired - Lifetime
- 1998-02-06 DE DE69824157T patent/DE69824157T2/de not_active Expired - Fee Related
- 1998-02-06 YU YU41299A patent/YU41299A/sh unknown
- 1998-02-06 JP JP10537448A patent/JP2000509731A/ja active Pending
- 1998-02-06 IL IL13090098A patent/IL130900A0/xx unknown
- 1998-02-06 PL PL98335418A patent/PL335418A1/xx unknown
- 1998-02-06 DK DK98900978T patent/DK0968194T3/da active
- 1998-02-06 NZ NZ336628A patent/NZ336628A/xx unknown
- 1998-02-06 EA EA199900693A patent/EA001963B1/ru not_active IP Right Cessation
- 1998-02-06 BR BR9807872A patent/BR9807872A/pt not_active Application Discontinuation
- 1998-02-06 TR TR1999/02093T patent/TR199902093T2/xx unknown
- 1998-02-06 CN CN98802638A patent/CN1248248A/zh active Pending
- 1998-02-06 SK SK1132-99A patent/SK113299A3/sk unknown
- 1998-02-06 CA CA002282277A patent/CA2282277C/fr not_active Expired - Fee Related
- 1998-02-06 KR KR1019997007887A patent/KR100358636B1/ko not_active IP Right Cessation
- 1998-02-06 AT AT98900978T patent/ATE267817T1/de not_active IP Right Cessation
- 1998-02-06 PT PT98900978T patent/PT968194E/pt unknown
- 1998-02-06 AU AU56768/98A patent/AU744028B2/en not_active Ceased
- 1998-02-06 HU HU0000914A patent/HUP0000914A3/hu unknown
- 1998-02-06 ES ES98900978T patent/ES2219866T3/es not_active Expired - Lifetime
- 1998-02-06 WO PCT/IB1998/000150 patent/WO1998038173A1/fr not_active Application Discontinuation
- 1998-02-17 PA PA19988447001A patent/PA8447001A1/es unknown
- 1998-02-19 GT GT199800038A patent/GT199800038A/es unknown
- 1998-02-20 UY UY24897A patent/UY24897A1/es not_active Application Discontinuation
- 1998-02-23 PE PE1998000126A patent/PE58399A1/es not_active Application Discontinuation
- 1998-02-25 TN TNTNSN98035A patent/TNSN98035A1/fr unknown
- 1998-02-25 MA MA24978A patent/MA24484A1/fr unknown
- 1998-02-25 TW TW087102714A patent/TW504508B/zh not_active IP Right Cessation
- 1998-02-25 DZ DZ980050A patent/DZ2440A1/fr active
- 1998-02-26 AP APAP/P/1998/001199A patent/AP859A/en active
- 1998-02-26 AR ARP980100871A patent/AR011170A1/es not_active Application Discontinuation
- 1998-02-27 HR HR60/038,905A patent/HRP980106A2/hr not_active Application Discontinuation
- 1998-02-27 ZA ZA9801666A patent/ZA981666B/xx unknown
- 1998-06-02 UA UA99084849A patent/UA61097C2/uk unknown
-
1999
- 1999-07-30 IS IS5140A patent/IS1952B/is unknown
- 1999-08-20 OA OA9900187A patent/OA11089A/en unknown
- 1999-08-24 BG BG103689A patent/BG103689A/bg unknown
- 1999-08-27 NO NO19994177A patent/NO313630B1/no not_active IP Right Cessation
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