DK3272764T3 - Fremgangsmåde til affinitetskromatografi - Google Patents

Fremgangsmåde til affinitetskromatografi Download PDF

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Publication number
DK3272764T3
DK3272764T3 DK17188657.5T DK17188657T DK3272764T3 DK 3272764 T3 DK3272764 T3 DK 3272764T3 DK 17188657 T DK17188657 T DK 17188657T DK 3272764 T3 DK3272764 T3 DK 3272764T3
Authority
DK
Denmark
Prior art keywords
procedure
affinity chromatography
affinity
chromatography
Prior art date
Application number
DK17188657.5T
Other languages
English (en)
Inventor
Achim Frauenschuh
Kurt Bill
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=43598315&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK3272764(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Application granted granted Critical
Publication of DK3272764T3 publication Critical patent/DK3272764T3/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 - B01D15/36
    • B01D15/3804—Affinity chromatography
    • B01D15/3809—Affinity chromatography of the antigen-antibody type, e.g. protein A, G, L chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK17188657.5T 2009-12-18 2010-12-17 Fremgangsmåde til affinitetskromatografi DK3272764T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US28805909P 2009-12-18 2009-12-18
EP10790452.6A EP2513134B1 (en) 2009-12-18 2010-12-17 Wash solution and method for affinity chromatography

Publications (1)

Publication Number Publication Date
DK3272764T3 true DK3272764T3 (da) 2024-05-06

Family

ID=43598315

Family Applications (2)

Application Number Title Priority Date Filing Date
DK17188657.5T DK3272764T3 (da) 2009-12-18 2010-12-17 Fremgangsmåde til affinitetskromatografi
DK10790452.6T DK2513134T3 (da) 2009-12-18 2010-12-17 Vaskeopløsning og fremgangsmåde til affinitetschromatografi

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK10790452.6T DK2513134T3 (da) 2009-12-18 2010-12-17 Vaskeopløsning og fremgangsmåde til affinitetschromatografi

Country Status (18)

Country Link
US (3) US9505803B2 (da)
EP (2) EP2513134B1 (da)
JP (2) JP5909450B2 (da)
KR (1) KR101858266B1 (da)
CN (1) CN102725304B (da)
AU (1) AU2010332778B2 (da)
BR (1) BR112012014937B1 (da)
CA (1) CA2784278C (da)
DK (2) DK3272764T3 (da)
ES (1) ES2651065T3 (da)
IL (1) IL220164B (da)
LT (2) LT2513134T (da)
MX (1) MX2012007103A (da)
PL (2) PL3272764T3 (da)
PT (2) PT3272764T (da)
RU (1) RU2564569C2 (da)
SG (2) SG181771A1 (da)
WO (1) WO2011073389A1 (da)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8911964B2 (en) 2006-09-13 2014-12-16 Abbvie Inc. Fed-batch method of making human anti-TNF-alpha antibody
KR20090074040A (ko) 2006-09-13 2009-07-03 아보트 러보러터리즈 세포 배양의 개선
SG10201702951RA (en) 2008-10-20 2017-06-29 Abbvie Inc Viral inactivation during purification of antibodies
SG10201702922VA (en) 2008-10-20 2017-06-29 Abbvie Inc Isolation and purification of antibodies using protein a affinity chromatography
PT3272764T (pt) * 2009-12-18 2024-04-24 Novartis Ag Método para cromatografia de afinidade
AU2011208659B2 (en) * 2010-01-22 2015-05-28 Boehringer Ingelheim International Gmbh Chromatographic method for purifying Fc-containing proteins
CA2834300C (en) * 2011-06-01 2022-01-11 Novartis Ag Wash solution and method for affinity chromatography
PL3418306T3 (pl) 2011-10-11 2024-04-15 F. Hoffmann-La Roche Ag Ulepszone składanie przeciwciał dwuswoistych
CA2910065C (en) * 2013-05-15 2023-09-19 Medimmune Limited Purification of recombinantly produced polypeptides
CN105848746B (zh) * 2013-09-05 2019-07-09 豪夫迈·罗氏有限公司 用于层析重复利用的方法
CN105407905B (zh) 2014-01-03 2020-03-03 生物辐射实验室股份有限公司 蛋白a洗脱产物中杂质的去除
US11566082B2 (en) 2014-11-17 2023-01-31 Cytiva Bioprocess R&D Ab Mutated immunoglobulin-binding polypeptides
WO2016149088A1 (en) 2015-03-13 2016-09-22 Bristol-Myers Squibb Company Use of alkaline washes during chromatography to remove impurities
JP6968055B2 (ja) 2015-08-21 2021-11-17 ジェネンテック， インコーポレイテッド アフィニティークロマトグラフィーにおける宿主細胞タンパク質の低減方法
US10654887B2 (en) 2016-05-11 2020-05-19 Ge Healthcare Bio-Process R&D Ab Separation matrix
US10730908B2 (en) 2016-05-11 2020-08-04 Ge Healthcare Bioprocess R&D Ab Separation method
CN109311948B (zh) 2016-05-11 2022-09-16 思拓凡生物工艺研发有限公司 清洁和/或消毒分离基质的方法
US10889615B2 (en) 2016-05-11 2021-01-12 Cytiva Bioprocess R&D Ab Mutated immunoglobulin-binding polypeptides
JP7106187B2 (ja) 2016-05-11 2022-07-26 サイティバ・バイオプロセス・アールアンドディ・アクチボラグ 分離マトリックスを保存する方法
US10703774B2 (en) 2016-09-30 2020-07-07 Ge Healthcare Bioprocess R&D Ab Separation method
US10513537B2 (en) 2016-05-11 2019-12-24 Ge Healthcare Bioprocess R&D Ab Separation matrix
MX2019000898A (es) * 2016-07-25 2019-07-01 Cephalon Inc Amortiguador de lavado de cromatografia de afinidad.
JP7097433B2 (ja) 2017-08-17 2022-07-07 ジャスト－エヴォテック バイオロジックス、インコーポレイテッド 宿主細胞ガレクチンおよび他の夾雑物からグリコシル化タンパク質を精製する方法
CN107793469B (zh) * 2017-10-16 2021-07-30 上海药明生物技术有限公司 一种去除宿主细胞蛋白含量的亲和纯化工艺
AU2018392697A1 (en) * 2017-12-21 2020-08-06 Genzyme Corporation Methods for enhanced removal of impurities during protein a chromatography
US11155575B2 (en) 2018-03-21 2021-10-26 Waters Technologies Corporation Non-antibody high-affinity-based sample preparation, sorbent, devices and methods
CN111954678A (zh) 2018-04-02 2020-11-17 美国安进公司 厄瑞努单抗组合物及其用途
EP4041745A4 (en) * 2019-10-08 2024-02-07 Univ North Carolina State PEPTIDES FOR PURIFYING IMMUNOGLOBULINS AND THEIR USE
CA3176109A1 (en) * 2020-03-27 2021-09-30 Haemalogix Pty Ltd Composition and method
EP4143203A1 (en) * 2020-04-27 2023-03-08 Alexion Pharmaceuticals, Inc. Protein a chromatography purification of an antibody
CN112827217A (zh) * 2020-12-29 2021-05-25 苏州良辰生物医药科技有限公司 一种层析柱清洗液及其应用

Family Cites Families (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4704366A (en) 1984-06-22 1987-11-03 Bio-Rad Laboratories, Inc. Process for binding IgG to protein A
US4857320A (en) * 1987-02-19 1989-08-15 Monsanto Company Method of enhancing the solubility of tissue plasminogen activator
JPH01238534A (ja) * 1988-03-17 1989-09-22 Mitsui Toatsu Chem Inc エンドトキシンの除去方法
US5429746A (en) 1994-02-22 1995-07-04 Smith Kline Beecham Corporation Antibody purification
ES2337091T3 (es) 1996-11-27 2010-04-20 Genentech, Inc. Purificacion por afinidad de polipeptido en una matriz de proteina.
PT1308455E (pt) 1998-05-06 2006-08-31 Genentech Inc Composicao compreendendo anticorpos anti-her2
ATE274522T1 (de) 1998-06-01 2004-09-15 Genentech Inc Abtrennung von antikörper-monomeren von deren multimeren mittels ionaustausch-chromatographie
WO2002072615A1 (fr) 2001-03-09 2002-09-19 Chugai Seiyaku Kabushiki Kaisha Methode de purification de proteines
US7223848B2 (en) 2001-06-05 2007-05-29 Genetics Institute, Llc Methods for purifying Fc-containing proteins
JP4460302B2 (ja) 2002-02-05 2010-05-12 ジェネンテック インコーポレイテッド タンパク質精製法
SI1561756T1 (sl) 2002-09-11 2016-02-29 Chugai Seiyaku Kabushiki Kaisha Postopek čiščenja proteinov
WO2004037203A2 (en) * 2002-10-24 2004-05-06 Enos Pharmaceuticals, Inc. Sustained release l-arginine formulations and methods of manufacture and use
CN100369930C (zh) * 2002-11-26 2008-02-20 Pdl生物制药股份有限公司 调节血管生成的α5β1整合素的嵌合的和人源化的抗体
SI1599222T1 (sl) * 2003-01-08 2009-08-31 Novartis Vaccines & Diagnostic Stabilizirani vodni sestavki, ki obsegajo inhibitor poti tkivnega faktorja (TFPI) ali varianto inhibitorja poti tkivnega faktorja
GB0304576D0 (en) 2003-02-28 2003-04-02 Lonza Biologics Plc Protein a chromatography
AU2004215653B2 (en) 2003-02-28 2011-03-17 Lonza Biologics Plc. Antibody purification by protein A and ion exchange chromatography
EP2336172B1 (en) 2003-10-27 2014-12-10 Wyeth LLC Removal of high molecular weight aggregates using hydroxyapatite chromatography
US8084032B2 (en) * 2004-01-21 2011-12-27 Ajinomoto Co., Inc. Purification method which prevents denaturation of an antibody
EP1698637B1 (en) 2005-03-03 2008-10-15 Ajinomoto Co., Inc. A method for improving recovery yield in protein purification with gel filtration chromatography using arginine
HUE049797T2 (hu) * 2005-03-11 2020-10-28 Wyeth Llc Gyenge megoszlási kromatográfiás eljárás
WO2007081851A2 (en) 2006-01-06 2007-07-19 Millipore Corporation Affinity chromatography matrices and methods of making and using the same
WO2007109163A2 (en) 2006-03-16 2007-09-27 Amgen Inc Wash buffer and method of using
CN101437839A (zh) 2006-03-20 2009-05-20 米德列斯公司 蛋白质纯化
EP2024386A2 (en) * 2006-06-02 2009-02-18 Wyeth Use of proteins and peptides of the tgf-beta superfamily for purification and therapeutic methods
US7754689B2 (en) 2006-06-02 2010-07-13 Wyeth Llc Finger-1 peptide analogs of the TGF-β superfamily
KR101770312B1 (ko) 2006-08-28 2017-08-22 아레스 트레이딩 에스.에이. Ｆｃ­함유 단백질을 정제하는 방법
MX2009002576A (es) * 2006-09-08 2009-03-20 Wyeth Corp Lavado de arginina en purificacion de proteina utilizando cromatografia de afinidad.
AU2008206923A1 (en) 2007-01-17 2008-07-24 Merck Serono S.A. Process for the purification of Fc-containing proteins
CN101679509A (zh) 2007-06-01 2010-03-24 弗·哈夫曼-拉罗切有限公司 免疫球蛋白纯化
CN103396480A (zh) 2008-05-15 2013-11-20 诺沃—诺迪斯克有限公司 抗体纯化方法
WO2010019493A1 (en) 2008-08-14 2010-02-18 Merck Sharp & Dohme Corp. Methods for purifying antibodies using protein a affinity chromatography
PT3272764T (pt) 2009-12-18 2024-04-24 Novartis Ag Método para cromatografia de afinidade
CA2834300C (en) * 2011-06-01 2022-01-11 Novartis Ag Wash solution and method for affinity chromatography

Also Published As

Publication number Publication date
AU2010332778A1 (en) 2012-07-19
SG10201408384PA (en) 2015-01-29
BR112012014937B1 (pt) 2021-01-19
JP5909450B2 (ja) 2016-04-26
US20120283416A1 (en) 2012-11-08
ES2651065T3 (es) 2018-01-24
JP2016128495A (ja) 2016-07-14
EP2513134B1 (en) 2017-09-06
PL2513134T3 (pl) 2018-02-28
PT2513134T (pt) 2017-12-14
CA2784278C (en) 2019-02-26
US9505803B2 (en) 2016-11-29
RU2564569C2 (ru) 2015-10-10
EP2513134A1 (en) 2012-10-24
RU2012130151A (ru) 2014-01-27
CN102725304A (zh) 2012-10-10
CN102725304B (zh) 2015-12-09
IL220164B (en) 2019-02-28
LT3272764T (lt) 2024-05-10
KR20120109506A (ko) 2012-10-08
MX2012007103A (es) 2012-07-17
BR112012014937A2 (pt) 2016-03-08
CA2784278A1 (en) 2011-06-23
KR101858266B1 (ko) 2018-05-15
WO2011073389A1 (en) 2011-06-23
SG181771A1 (en) 2012-07-30
DK2513134T3 (da) 2017-12-18
PL3272764T3 (pl) 2024-06-10
PT3272764T (pt) 2024-04-24
EP3272764B1 (en) 2024-02-07
IL220164A0 (en) 2012-07-31
JP2013514073A (ja) 2013-04-25
EP3272764A1 (en) 2018-01-24
AU2010332778B2 (en) 2015-03-19
US20190233469A1 (en) 2019-08-01
US20170044211A1 (en) 2017-02-16
LT2513134T (lt) 2017-11-27

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