LT3272764T - Giminingumo chromatografijos metodas - Google Patents

Giminingumo chromatografijos metodas

Info

Publication number
LT3272764T
LT3272764T LTEP17188657.5T LT17188657T LT3272764T LT 3272764 T LT3272764 T LT 3272764T LT 17188657 T LT17188657 T LT 17188657T LT 3272764 T LT3272764 T LT 3272764T
Authority
LT
Lithuania
Prior art keywords
affinity chromatography
affinity
chromatography
Prior art date
Application number
LTEP17188657.5T
Other languages
English (en)
Inventor
Achim Frauenschuh
Kurt Bill
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=43598315&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=LT3272764(T) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of LT3272764T publication Critical patent/LT3272764T/lt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/16Extraction; Separation; Purification by chromatography
    • C07K1/22Affinity chromatography or related techniques based upon selective absorption processes
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D15/00Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08Selective adsorption, e.g. chromatography
    • B01D15/26Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/38Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 - B01D15/36
    • B01D15/3804Affinity chromatography
    • B01D15/3809Affinity chromatography of the antigen-antibody type, e.g. protein A, G, L chromatography
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
LTEP17188657.5T 2009-12-18 2010-12-17 Giminingumo chromatografijos metodas LT3272764T (lt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US28805909P 2009-12-18 2009-12-18

Publications (1)

Publication Number Publication Date
LT3272764T true LT3272764T (lt) 2024-05-10

Family

ID=43598315

Family Applications (2)

Application Number Title Priority Date Filing Date
LTEP10790452.6T LT2513134T (lt) 2009-12-18 2010-12-17 Praplovimo tirpalas ir afininės chromatografijos metodas
LTEP17188657.5T LT3272764T (lt) 2009-12-18 2010-12-17 Giminingumo chromatografijos metodas

Family Applications Before (1)

Application Number Title Priority Date Filing Date
LTEP10790452.6T LT2513134T (lt) 2009-12-18 2010-12-17 Praplovimo tirpalas ir afininės chromatografijos metodas

Country Status (18)

Country Link
US (3) US9505803B2 (lt)
EP (2) EP3272764B1 (lt)
JP (2) JP5909450B2 (lt)
KR (1) KR101858266B1 (lt)
CN (1) CN102725304B (lt)
AU (1) AU2010332778B2 (lt)
BR (1) BR112012014937B1 (lt)
CA (1) CA2784278C (lt)
DK (2) DK3272764T3 (lt)
ES (1) ES2651065T3 (lt)
IL (1) IL220164B (lt)
LT (2) LT2513134T (lt)
MX (1) MX2012007103A (lt)
PL (2) PL3272764T3 (lt)
PT (2) PT2513134T (lt)
RU (1) RU2564569C2 (lt)
SG (2) SG10201408384PA (lt)
WO (1) WO2011073389A1 (lt)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8911964B2 (en) 2006-09-13 2014-12-16 Abbvie Inc. Fed-batch method of making human anti-TNF-alpha antibody
BRPI0716762A2 (pt) 2006-09-13 2013-09-24 Abbott Lab melhorias da cultura celular
EP2921501A1 (en) 2008-10-20 2015-09-23 Abbvie Inc. Isolation and purification of antibodies using Protein A affinity chromatography
CA2738499A1 (en) 2008-10-20 2010-04-29 Abbott Laboratories Viral inactivation during purification of antibodies
SG10201408384PA (en) 2009-12-18 2015-01-29 Novartis Ag Wash solution and method for affinity chromatography
EP2526114B1 (de) 2010-01-22 2014-06-18 Boehringer Ingelheim International GmbH Chromatographisches verfahren zur aufreinigung von fc enthaltenden proteinen
KR101953405B1 (ko) * 2011-06-01 2019-02-28 노파르티스 아게 친화성 크로마토그래피를 위한 세척 용액 및 방법
KR102106002B1 (ko) 2011-10-11 2020-05-07 제넨테크, 인크. 이중특이적 항체의 개선된 어셈블리
WO2014186350A1 (en) * 2013-05-15 2014-11-20 Medimmune Limited Purification of recombinantly produced polypeptides
JP6602765B2 (ja) 2013-09-05 2019-11-06 ジェネンテック, インコーポレイテッド クロマトグラフィー再使用のための方法
EP2986307A4 (en) 2014-01-03 2017-04-12 Bio-rad Laboratories, Inc. Removal of impurities from protein a eluates
US11566082B2 (en) 2014-11-17 2023-01-31 Cytiva Bioprocess R&D Ab Mutated immunoglobulin-binding polypeptides
EP3268100A1 (en) 2015-03-13 2018-01-17 Bristol-Myers Squibb Company Use of alkaline washes during chromatography to remove impurities
EP3337812B1 (en) 2015-08-21 2021-04-28 F. Hoffmann-La Roche AG Method for the reduction of host cell proteins in affinity chromatography
CN109311949B (zh) 2016-05-11 2022-09-16 思拓凡生物工艺研发有限公司 储存分离基质的方法
US10703774B2 (en) 2016-09-30 2020-07-07 Ge Healthcare Bioprocess R&D Ab Separation method
US11753438B2 (en) 2016-05-11 2023-09-12 Cytiva Bioprocess R&D Ab Method of cleaning and/or sanitizing a separation matrix
ES2874974T3 (es) 2016-05-11 2021-11-05 Cytiva Bioprocess R & D Ab Matriz de separación
US10654887B2 (en) 2016-05-11 2020-05-19 Ge Healthcare Bio-Process R&D Ab Separation matrix
US10730908B2 (en) 2016-05-11 2020-08-04 Ge Healthcare Bioprocess R&D Ab Separation method
US10889615B2 (en) 2016-05-11 2021-01-12 Cytiva Bioprocess R&D Ab Mutated immunoglobulin-binding polypeptides
US10688412B2 (en) * 2016-07-25 2020-06-23 Cehpalon, Inc. Affinity chromatography wash buffer
DK3668985T3 (da) 2017-08-17 2021-09-20 Just Evotec Biologics Inc Fremgangsmåde til rensning af glycosyleret protein fra værtscellegalectiner og andre urenheder
CN107793469B (zh) * 2017-10-16 2021-07-30 上海药明生物技术有限公司 一种去除宿主细胞蛋白含量的亲和纯化工艺
SG11202005809TA (en) * 2017-12-21 2020-07-29 Genzyme Corp Methods for enhanced removal of impurities during protein a chromatography
CN111902720A (zh) 2018-03-21 2020-11-06 沃特世科技公司 基于非抗体高亲和力的样品制备、吸附剂、装置和方法
JP2021519790A (ja) 2018-04-02 2021-08-12 アムジェン インコーポレイテッド エレヌマブ組成物及びその使用
US11612885B2 (en) * 2018-05-08 2023-03-28 Waters Technologies Corporation Methods, compositions and kits useful for pH gradient cation exchange chromatography
CN114502569A (zh) * 2019-10-08 2022-05-13 北卡罗莱纳州立大学 免疫球蛋白纯化肽及其用途
CN115551877A (zh) * 2020-03-27 2022-12-30 哈马洛吉克斯有限公司 组合物和方法
US20230143163A1 (en) * 2020-04-27 2023-05-11 Alexion Pharmaceuticals, Inc. Protein a chromatography purification of an antibody
CN112827217A (zh) * 2020-12-29 2021-05-25 苏州良辰生物医药科技有限公司 一种层析柱清洗液及其应用
WO2024126337A1 (en) * 2022-12-12 2024-06-20 H. Lundbeck A/S Arginine wash in protein purification

Family Cites Families (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4704366A (en) 1984-06-22 1987-11-03 Bio-Rad Laboratories, Inc. Process for binding IgG to protein A
US4857320A (en) * 1987-02-19 1989-08-15 Monsanto Company Method of enhancing the solubility of tissue plasminogen activator
JPH01238534A (ja) * 1988-03-17 1989-09-22 Mitsui Toatsu Chem Inc エンドトキシンの除去方法
US5429746A (en) 1994-02-22 1995-07-04 Smith Kline Beecham Corporation Antibody purification
DE69739673D1 (de) 1996-11-27 2009-12-31 Genentech Inc Affinitätsreinigung von Polypeptid-Proteinen auf einer Protein A Matrix
SI1308455T1 (sl) 1998-05-06 2006-08-31 Genentech Inc Sestavek, ki obsega protitelesa anti-HER2
DE69919701T2 (de) 1998-06-01 2005-09-15 Genentech, Inc., South San Francisco Abtrennung von antikörper-monomeren von deren multimeren mittels ionaustausch-chromatographie
EP3088412B1 (en) 2001-03-09 2021-05-05 Chugai Seiyaku Kabushiki Kaisha Protein purification method
DK1714982T3 (da) 2001-06-05 2009-05-04 Genetics Inst Llc Fremgangsmåde til rensning af stærkt anioniske proteiner
EP2048154B2 (en) 2002-02-05 2015-06-03 Genentech, Inc. Protein purification
ES2626268T3 (es) 2002-09-11 2017-07-24 Chugai Seiyaku Kabushiki Kaisha Método de purificación de proteínas
KR20050083827A (ko) * 2002-10-24 2005-08-26 이노스 파마슈티칼스, 인코포레이티드 서방성 l-아르기닌 포뮬레이션 및 이의 제조방법 및 용도
CN100369930C (zh) * 2002-11-26 2008-02-20 Pdl生物制药股份有限公司 调节血管生成的α5β1整合素的嵌合的和人源化的抗体
EA008038B1 (ru) * 2003-01-08 2007-02-27 Чирон Корпорейшн Стабилизированные водные композиции, содержащие ингибитор пути метаболизма, тканевого фактора (tfpi) или вариант ингибитора пути метаболизма тканевого фактора
GB0304576D0 (en) 2003-02-28 2003-04-02 Lonza Biologics Plc Protein a chromatography
DK1601697T3 (da) 2003-02-28 2007-10-01 Lonza Biologics Plc Oprensning af antistof ved protein A- og ionbytningskromatografi
PT1678208E (pt) 2003-10-27 2013-07-10 Wyeth Llc Remoção de agregados de elevado peso molecular utilizando cromatografia de hidroxiapatite
US8084032B2 (en) 2004-01-21 2011-12-27 Ajinomoto Co., Inc. Purification method which prevents denaturation of an antibody
EP1698637B1 (en) 2005-03-03 2008-10-15 Ajinomoto Co., Inc. A method for improving recovery yield in protein purification with gel filtration chromatography using arginine
KR101660575B1 (ko) * 2005-03-11 2016-09-27 와이어쓰 엘엘씨 약한 분배성 크로마토그래피법
EP1974215B1 (en) 2006-01-06 2017-12-27 EMD Millipore Corporation Affinity chromatography matrices and methods of making and using the same
US8263750B2 (en) 2006-03-16 2012-09-11 Amgen Inc. Method for purifying a protein using protein-A affinity chromatography using an intermediate wash step
CA2645739A1 (en) 2006-03-20 2007-09-27 Medarex, Inc. Protein purification
US7754689B2 (en) * 2006-06-02 2010-07-13 Wyeth Llc Finger-1 peptide analogs of the TGF-β superfamily
EP2377876A1 (en) * 2006-06-02 2011-10-19 Wyeth LLC Use of proteins and peptides of the TGF-BETA superfamily for purification and therapeutic methods
FI2061803T4 (fi) 2006-08-28 2023-03-14 Process for the purification of fc-containing proteins
JP5386354B2 (ja) 2006-09-08 2014-01-15 ワイス・エルエルシー アフィニティークロマトグラフィーを使用するタンパク質精製におけるアルギニン洗浄
AU2008206923A1 (en) 2007-01-17 2008-07-24 Merck Serono S.A. Process for the purification of Fc-containing proteins
US9493548B2 (en) 2007-06-01 2016-11-15 Hoffmann-La Roche Inc. Immunoglobulin purification
CN102027010A (zh) 2008-05-15 2011-04-20 诺沃-诺迪斯克有限公司 抗体纯化方法
MX2011001696A (es) 2008-08-14 2011-03-25 Merck Sharp & Dohme Metodos para purificar anticuerpos usando cromatografia de afinidad con proteina a.
SG10201408384PA (en) * 2009-12-18 2015-01-29 Novartis Ag Wash solution and method for affinity chromatography
KR101953405B1 (ko) * 2011-06-01 2019-02-28 노파르티스 아게 친화성 크로마토그래피를 위한 세척 용액 및 방법

Also Published As

Publication number Publication date
RU2564569C2 (ru) 2015-10-10
PL2513134T3 (pl) 2018-02-28
PL3272764T3 (pl) 2024-06-10
RU2012130151A (ru) 2014-01-27
EP2513134A1 (en) 2012-10-24
JP2016128495A (ja) 2016-07-14
DK2513134T3 (en) 2017-12-18
IL220164A0 (en) 2012-07-31
CA2784278C (en) 2019-02-26
EP2513134B1 (en) 2017-09-06
BR112012014937B1 (pt) 2021-01-19
KR101858266B1 (ko) 2018-05-15
LT2513134T (lt) 2017-11-27
KR20120109506A (ko) 2012-10-08
JP5909450B2 (ja) 2016-04-26
EP3272764B1 (en) 2024-02-07
DK3272764T3 (da) 2024-05-06
CN102725304A (zh) 2012-10-10
PT3272764T (pt) 2024-04-24
SG10201408384PA (en) 2015-01-29
EP3272764A1 (en) 2018-01-24
JP2013514073A (ja) 2013-04-25
IL220164B (en) 2019-02-28
WO2011073389A1 (en) 2011-06-23
MX2012007103A (es) 2012-07-17
CN102725304B (zh) 2015-12-09
SG181771A1 (en) 2012-07-30
ES2651065T3 (es) 2018-01-24
US20170044211A1 (en) 2017-02-16
CA2784278A1 (en) 2011-06-23
PT2513134T (pt) 2017-12-14
US9505803B2 (en) 2016-11-29
AU2010332778B2 (en) 2015-03-19
US20120283416A1 (en) 2012-11-08
AU2010332778A1 (en) 2012-07-19
US20190233469A1 (en) 2019-08-01
BR112012014937A2 (pt) 2016-03-08

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