DK2209888T3 - Forbedrede fremgangsmåder til fremstilling af rpe-celler og sammensætninger af rpe-celler - Google Patents
Forbedrede fremgangsmåder til fremstilling af rpe-celler og sammensætninger af rpe-celler Download PDFInfo
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- DK2209888T3 DK2209888T3 DK08839134.7T DK08839134T DK2209888T3 DK 2209888 T3 DK2209888 T3 DK 2209888T3 DK 08839134 T DK08839134 T DK 08839134T DK 2209888 T3 DK2209888 T3 DK 2209888T3
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- rpe cells
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- improved procedures
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0618—Cells of the nervous system
- C12N5/0621—Eye cells, e.g. cornea, iris pigmented cells
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/30—Nerves; Brain; Eyes; Corneal cells; Cerebrospinal fluid; Neuronal stem cells; Neuronal precursor cells; Glial cells; Oligodendrocytes; Schwann cells; Astroglia; Astrocytes; Choroid plexus; Spinal cord tissue
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/70—Enzymes
- C12N2501/73—Hydrolases (EC 3.)
- C12N2501/734—Proteases (EC 3.4.)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/02—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from embryonic cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2509/00—Methods for the dissociation of cells, e.g. specific use of enzymes
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/50—Proteins
- C12N2533/54—Collagen; Gelatin
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- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Ophthalmology & Optometry (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Cell Biology (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Developmental Biology & Embryology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Epidemiology (AREA)
- Virology (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Urology & Nephrology (AREA)
- Psychology (AREA)
- Vascular Medicine (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Materials For Medical Uses (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US99866807P | 2007-10-12 | 2007-10-12 | |
US99876607P | 2007-10-12 | 2007-10-12 | |
US990808P | 2008-01-02 | 2008-01-02 | |
US991108P | 2008-01-02 | 2008-01-02 | |
PCT/US2008/011669 WO2009051671A1 (en) | 2007-10-12 | 2008-10-10 | Improved methods of producing rpe cells and compositions of rpe cells |
Publications (1)
Publication Number | Publication Date |
---|---|
DK2209888T3 true DK2209888T3 (da) | 2020-01-20 |
Family
ID=40567677
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK08839134.7T DK2209888T3 (da) | 2007-10-12 | 2008-10-10 | Forbedrede fremgangsmåder til fremstilling af rpe-celler og sammensætninger af rpe-celler |
Country Status (13)
Country | Link |
---|---|
US (4) | US20110274662A1 (da) |
EP (2) | EP2209888B1 (da) |
JP (5) | JP2011500024A (da) |
KR (2) | KR101849336B1 (da) |
CN (2) | CN104946591A (da) |
AU (1) | AU2008312007A1 (da) |
CA (3) | CA3177952A1 (da) |
DK (1) | DK2209888T3 (da) |
ES (1) | ES2764473T3 (da) |
IL (3) | IL292561A (da) |
PL (1) | PL2209888T3 (da) |
PT (1) | PT2209888T (da) |
WO (1) | WO2009051671A1 (da) |
Families Citing this family (47)
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BRPI0507074A (pt) | 2004-01-23 | 2007-06-19 | Advanced Cell Tech Inc | modalidades aperfeiçoadas para o tratamento de doenças degenerativas da retina |
US7794704B2 (en) * | 2004-01-23 | 2010-09-14 | Advanced Cell Technology, Inc. | Methods for producing enriched populations of human retinal pigment epithelium cells for treatment of retinal degeneration |
WO2008087917A1 (ja) | 2007-01-18 | 2008-07-24 | Riken | 視細胞への分化誘導方法 |
DK2209888T3 (da) | 2007-10-12 | 2020-01-20 | Astellas Inst For Regenerative Medicine | Forbedrede fremgangsmåder til fremstilling af rpe-celler og sammensætninger af rpe-celler |
WO2009132156A1 (en) * | 2008-04-22 | 2009-10-29 | Regenerative Research Foundation | Retinal pigment epithelial stem cells |
WO2009148170A1 (ja) | 2008-06-06 | 2009-12-10 | 独立行政法人理化学研究所 | 幹細胞の培養方法 |
ES2509567T3 (es) * | 2009-08-28 | 2014-10-17 | Cellular Dynamics International, Inc. | Identificación de variación genética en tejidos afectados |
DK2496688T3 (da) * | 2009-11-05 | 2017-04-03 | Riken | Fremgangsmåde til induktion af differentiering hos dyrkede stamceller |
IL281453B (en) | 2009-11-17 | 2022-07-01 | Astellas Inst For Regenerative Medicine | Methods for preparing human rpe cells and pharmaceutical preparations of human rpe cells |
CA2783699C (en) | 2009-12-08 | 2019-01-15 | Case Western Reserve University | Primary amine compounds for treating ocular disorders |
PL2596119T3 (pl) * | 2010-07-23 | 2021-12-06 | Astellas Institute For Regenerative Medicine | Sposoby wykrywania rzadkich subpopulacji komórek i kompozycje wysoko oczyszczonych komórek |
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KR101972610B1 (ko) | 2011-05-18 | 2019-04-25 | 더 리젠츠 오브 더 유니버시티 오브 캘리포니아 | 망막 질환을 치료하기 위한 조성물 및 방법 |
EP3563860A1 (en) * | 2011-11-14 | 2019-11-06 | Astellas Institute for Regenerative Medicine | Pharmaceutical preparations of human rpe cells and uses thereof |
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JP5985208B2 (ja) * | 2011-11-25 | 2016-09-06 | 住友化学株式会社 | 網膜組織の製造方法 |
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CA2856867C (en) | 2011-11-25 | 2021-06-01 | Sumitomo Chemical Company, Limited | Methods for producing retinal tissue and retina-related cell |
JP5985207B2 (ja) * | 2011-11-25 | 2016-09-06 | 住友化学株式会社 | 網膜色素上皮細胞の製造方法 |
JP5985209B2 (ja) * | 2011-11-25 | 2016-09-06 | 住友化学株式会社 | 眼杯様構造体の製造方法 |
AU2012345630A1 (en) | 2011-11-30 | 2014-07-17 | Astellas Institute For Regenerative Medicine | Mesenchymal stromal cells and uses related thereto |
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US10519422B2 (en) * | 2012-02-29 | 2019-12-31 | Riken | Method of producing human retinal pigment epithelial cells |
EP2934555B1 (en) * | 2012-12-21 | 2021-09-22 | Astellas Institute for Regenerative Medicine | Methods for production of platelets from pluripotent stem cells |
CA2899865C (en) | 2013-02-01 | 2023-10-10 | Kapil BHARTI | Method for generating retinal pigment epithelium (rpe) cells from induced pluripotent stem cells (ipscs) |
EP2828380B1 (en) * | 2013-04-03 | 2016-09-21 | Tampereen Yliopisto | Methods and media for differentiating eye cells |
EP3656853B1 (en) | 2013-08-23 | 2023-02-15 | Sumitomo Chemical Company, Limited | Method for producing retinal tissue and retina-related cells |
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KR102511192B1 (ko) | 2014-10-24 | 2023-03-17 | 스미토모 파마 가부시키가이샤 | 망막 조직의 제조 방법 |
AU2015336453B2 (en) | 2014-10-24 | 2021-05-20 | Riken | Production method for nerve tissue |
JP6734853B2 (ja) * | 2014-12-18 | 2020-08-05 | ソルボンヌ・ユニヴェルシテSorbonne Universite | 網膜変性処置のためのotx2過剰発現トランスジェニック網膜色素上皮細胞 |
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AU2015373111B2 (en) * | 2014-12-30 | 2021-06-24 | Cell Cure Neurosciences Ltd. | Methods of treating retinal diseases |
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KR20180042436A (ko) * | 2015-09-08 | 2018-04-25 | 셀룰러 다이내믹스 인터내셔널, 인코포레이티드 | 줄기 세포에서 유래된 망막색소상피의 macs 기반 정제 |
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