DK2139477T3 - Pyrazolopyridinderivater som NADPH-oxidaseinhibitorer - Google Patents

Pyrazolopyridinderivater som NADPH-oxidaseinhibitorer

Info

Publication number: DK2139477T3
Authority: DK; Denmark
Prior art keywords: oxidase inhibitors; nadph oxidase; pyrazolopyridine derivatives; pyrazolopyridine; derivatives
Prior art date: 2007-03-22

Application number

DK08718102.0T

Other languages

English (en)

Inventor

Patrick Page

Mike Orchard

Bianca Mottironi

Laetitia Fioraso-Cartier

Original Assignee

Genkyotex Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2007-03-22

Filing date

2008-03-20

Publication date

2013-03-11

2008-03-20 Application filed by Genkyotex Sa filed Critical Genkyotex Sa

2013-03-11 Application granted granted Critical

2013-03-11 Publication of DK2139477T3 publication Critical patent/DK2139477T3/da

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
- A—HUMAN NECESSITIES
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- A61P9/12—Antihypertensives

DK08718102.0T 2007-03-22 2008-03-20 Pyrazolopyridinderivater som NADPH-oxidaseinhibitorer DK2139477T3 (da)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US89628407P	2007-03-22	2007-03-22
EP07109555A EP2002835A1 (en)	2007-06-04	2007-06-04	Pyrazolo pyridine derivatives as NADPH oxidase inhibitors
PCT/EP2008/053390 WO2008113856A1 (en)	2007-03-22	2008-03-20	Pyrazolo pyridine derivatives as nadph oxidase inhibitors

Publications (1)

Publication Number	Publication Date
DK2139477T3 true DK2139477T3 (da)	2013-03-11

Family

ID=38653574

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
DK08718102.0T DK2139477T3 (da)	2007-03-22	2008-03-20	Pyrazolopyridinderivater som NADPH-oxidaseinhibitorer
DK12187254.3T DK2545918T3 (da)	2007-03-22	2008-03-20	Pyrazolopyridinderivater som NADPH-oxidaseinhibitorer

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
DK12187254.3T DK2545918T3 (da)	2007-03-22	2008-03-20	Pyrazolopyridinderivater som NADPH-oxidaseinhibitorer

Country Status (18)

Country	Link
US (2)	US8389518B2 (da)
EP (3)	EP2002835A1 (da)
JP (2)	JP5715340B2 (da)
CN (2)	CN101686967B (da)
AU (1)	AU2008228186C1 (da)
BR (1)	BRPI0808824B8 (da)
CA (1)	CA2676954C (da)
CY (2)	CY1113556T1 (da)
DK (2)	DK2139477T3 (da)
ES (2)	ES2398994T3 (da)
HK (2)	HK1141734A1 (da)
HR (2)	HRP20130143T1 (da)
IL (1)	IL201009A (da)
PL (2)	PL2139477T3 (da)
PT (2)	PT2545918E (da)
RS (2)	RS52640B (da)
SI (2)	SI2139477T1 (da)
WO (1)	WO2008113856A1 (da)

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EP2000176A1 (en)	2007-06-04	2008-12-10	GenKyo Tex	Tetrahydroindole derivatives as NADPH Oxidase inhibitors
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EP2166009A1 (en)	2008-09-23	2010-03-24	Genkyo Tex Sa	Pyrazolo pyridine derivatives as nadph oxidase inhibitors
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EP2305679A1 (en)	2009-09-28	2011-04-06	GenKyoTex SA	Pyrazoline dione derivatives as nadph oxidase inhibitors
EP2512242B8 (en) *	2009-12-18	2015-12-09	GlaxoSmithKline Intellectual Property Limited	Novel compounds
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WO2012173952A1 (en)	2011-06-13	2012-12-20	Emory University	Piperazine derivatives, compositions, and uses related thereto
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WO2014153227A1 (en)	2013-03-14	2014-09-25	Eastern Virginia Medical School	Methods of preserving and protecting pancreatic beta cells and treating or preventing diabetes by inhibiting nox-1
EP2857399A1 (en)	2013-10-03	2015-04-08	GenKyoTex SA	Compounds useful for the treatment of PDE5 inhibitor-poorly responsive erectile dysfunction
EP3098220A1 (en)	2015-05-28	2016-11-30	GenKyoTex SA	Process for the preparation of a nadph oxidase inhibitor and its polymorphs and uses thereof
CA2989098A1 (en) *	2015-06-22	2016-12-29	Actelion Pharmaceuticals Ltd	Nadph oxidase 4 inhibitors
US11084796B2 (en)	2016-05-10	2021-08-10	Georgia State University Research Foundation, Inc.	Heterocyclic derivatives for the treatment of RSV
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WO2018152220A1 (en)	2017-02-15	2018-08-23	Incyte Corporation	Pyrazolopyridine compounds and uses thereof
WO2018203298A1 (en)	2017-05-04	2018-11-08	Glenmark Pharmaceuticals S.A.	Substituted bicyclic heterocyclic compounds as nadph oxidase inhibitors
WO2019023448A1 (en)	2017-07-26	2019-01-31	Emory University	INHIBITORS OF NADPH OXIDASE AND THEIR USE
US10722495B2 (en)	2017-09-08	2020-07-28	Incyte Corporation	Cyanoindazole compounds and uses thereof
EP3479843A1 (en)	2017-11-01	2019-05-08	GenKyoTex Suisse SA	Use of nox inhibitors for treatment of cancer
MX2020008656A (es)	2018-02-20	2020-12-09	Incyte Corp	Derivados de n-(fenil)-2-(fenil)pirimidina-4-carboxamida y compuestos relacionados como inhibidores de la cinasa de progenitores hematopoyeticos 1 (hpk1) para tratar el cancer.
US10752635B2 (en)	2018-02-20	2020-08-25	Incyte Corporation	Indazole compounds and uses thereof
US10745388B2 (en)	2018-02-20	2020-08-18	Incyte Corporation	Indazole compounds and uses thereof
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CN109846900B (zh) *	2018-05-25	2021-07-23	四川大学	还原型烟酰胺腺嘌呤二核苷酸磷酸在制备抗病毒药物中的用途
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Also Published As

Publication number	Publication date
HRP20141029T1 (hr)	2014-12-19
ES2512491T3 (es)	2014-10-24
JP2015134805A (ja)	2015-07-27
JP5715340B2 (ja)	2015-05-07
US20100048560A1 (en)	2010-02-25
US9073919B2 (en)	2015-07-07
RS53641B1 (en)	2015-04-30
JP2010521522A (ja)	2010-06-24
CY1113556T1 (el)	2016-06-22
BRPI0808824B1 (pt)	2020-10-13
EP2545918B1 (en)	2014-08-06
BRPI0808824B8 (pt)	2021-05-25
EP2139477B1 (en)	2012-12-12
CA2676954A1 (en)	2008-09-25
WO2008113856A1 (en)	2008-09-25
SI2139477T1 (sl)	2013-02-28
AU2008228186A1 (en)	2008-09-25
CN105061422B (zh)	2019-07-12
HK1141734A1 (en)	2010-11-19
CN101686967B (zh)	2015-08-19
RS52640B (en)	2013-06-28
ES2398994T3 (es)	2013-03-25
IL201009A0 (en)	2010-05-17
HRP20130143T1 (hr)	2013-03-31
SI2545918T1 (sl)	2014-12-31
US8389518B2 (en)	2013-03-05
PT2139477E (pt)	2013-02-07
AU2008228186C1 (en)	2012-12-06
BRPI0808824A2 (pt)	2014-08-19
CY1115633T1 (el)	2017-01-04
DK2545918T3 (da)	2014-11-10
PT2545918E (pt)	2014-11-03
IL201009A (en)	2016-03-31
PL2139477T3 (pl)	2013-05-31
AU2008228186B2 (en)	2012-06-14
PL2545918T3 (pl)	2015-03-31
HK1179871A1 (en)	2013-10-11
EP2139477A1 (en)	2010-01-06
CN101686967A (zh)	2010-03-31
CN105061422A (zh)	2015-11-18
EP2545918A1 (en)	2013-01-16
JP6047189B2 (ja)	2016-12-21
CA2676954C (en)	2016-01-12
EP2002835A1 (en)	2008-12-17
US20130123256A1 (en)	2013-05-16

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