DK134189D0 - Insulinforbindelser - Google Patents

Insulinforbindelser

Info

Publication number
DK134189D0
DK134189D0 DK134189A DK134189A DK134189D0 DK 134189 D0 DK134189 D0 DK 134189D0 DK 134189 A DK134189 A DK 134189A DK 134189 A DK134189 A DK 134189A DK 134189 D0 DK134189 D0 DK 134189D0
Authority
DK
Denmark
Prior art keywords
image
insulin compounds
coded
amino acid
acid residue
Prior art date
Application number
DK134189A
Other languages
Danish (da)
English (en)
Inventor
Per Balschmidt
Finn Benned Hansen
Original Assignee
Nordisk Gentofte
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nordisk Gentofte filed Critical Nordisk Gentofte
Priority to DK134189A priority Critical patent/DK134189D0/da
Publication of DK134189D0 publication Critical patent/DK134189D0/da
Priority to DK90905190.6T priority patent/DK0463072T3/da
Priority to HU902706A priority patent/HUT58349A/hu
Priority to AT90905190T priority patent/ATE116661T1/de
Priority to PCT/DK1990/000071 priority patent/WO1990011299A1/en
Priority to KR1019910701125A priority patent/KR920701250A/ko
Priority to DE69015811T priority patent/DE69015811T2/de
Priority to EP90905190A priority patent/EP0463072B1/en
Priority to CA002049961A priority patent/CA2049961A1/en
Priority to ES90905190T priority patent/ES2068384T3/es
Priority to AU53448/90A priority patent/AU637365B2/en
Priority to JP2505142A priority patent/JPH04503808A/ja
Priority to NZ232953A priority patent/NZ232953A/en
Priority to CN90101564A priority patent/CN1045793A/zh
Priority to DD90338860A priority patent/DD298788A5/de
Priority to ZA902086A priority patent/ZA902086B/xx
Priority to IL93792A priority patent/IL93792A0/xx
Priority to PT93502A priority patent/PT93502B/pt
Priority to YU53290A priority patent/YU53290A/sh
Priority to US07/495,798 priority patent/US5430016A/en
Priority to IE100490A priority patent/IE66564B1/en
Priority to GR900100206A priority patent/GR1002545B/el
Priority to NO913687A priority patent/NO300640B1/no
Priority to FI914419A priority patent/FI914419A0/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Toxicology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK134189A 1989-03-20 1989-03-20 Insulinforbindelser DK134189D0 (da)

Priority Applications (24)

Application Number Priority Date Filing Date Title
DK134189A DK134189D0 (da) 1989-03-20 1989-03-20 Insulinforbindelser
HU902706A HUT58349A (en) 1989-03-20 1990-03-15 Process for producing new isoleucine derivatives
AU53448/90A AU637365B2 (en) 1989-03-20 1990-03-15 Novel insulin compounds
JP2505142A JPH04503808A (ja) 1989-03-20 1990-03-15 新規インシュリン化合物
AT90905190T ATE116661T1 (de) 1989-03-20 1990-03-15 Insulinverbindungen.
PCT/DK1990/000071 WO1990011299A1 (en) 1989-03-20 1990-03-15 Novel insulin compounds
KR1019910701125A KR920701250A (ko) 1989-03-20 1990-03-15 신규 인슐린 화합물
DE69015811T DE69015811T2 (de) 1989-03-20 1990-03-15 Insulinverbindungen.
EP90905190A EP0463072B1 (en) 1989-03-20 1990-03-15 Novel insulin compounds
CA002049961A CA2049961A1 (en) 1989-03-20 1990-03-15 Insulin compounds
ES90905190T ES2068384T3 (es) 1989-03-20 1990-03-15 Nuevos compuestos de insulina.
DK90905190.6T DK0463072T3 (da) 1989-03-20 1990-03-15 Hidtil ukendte insulinforbindelser
NZ232953A NZ232953A (en) 1989-03-20 1990-03-16 Arg ao -insulin derivatives and pharmaceutical compositions
CN90101564A CN1045793A (zh) 1989-03-20 1990-03-19 新的胰岛素化合物及其制备方法
US07/495,798 US5430016A (en) 1989-03-20 1990-03-19 Insulin compounds and compositions
DD90338860A DD298788A5 (de) 1989-03-20 1990-03-19 Neue insulinverbindungen
ZA902086A ZA902086B (en) 1989-03-20 1990-03-19 Novel insulin compounds
IL93792A IL93792A0 (en) 1989-03-20 1990-03-19 Insulin compounds,their preparation and compositions comprising them
PT93502A PT93502B (pt) 1989-03-20 1990-03-19 Processo para a preparacao de novos derivados de insulina e de composicoes farmaceuticas que os contem
YU53290A YU53290A (sh) 1989-03-20 1990-03-19 Postupak za dobijanje novih jedinjenja insulina
IE100490A IE66564B1 (en) 1989-03-20 1990-03-20 Novel insulin compounds
GR900100206A GR1002545B (el) 1989-03-20 1990-03-20 Μεθοδος παρασκευης νεων συνθεσεων ινσουλινης.
NO913687A NO300640B1 (no) 1989-03-20 1991-09-19 Fremgangsmåte ved fremstilling av nye insulinforbindelser
FI914419A FI914419A0 (fi) 1989-03-20 1991-09-19 Nya insulinfoereningar.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK134189A DK134189D0 (da) 1989-03-20 1989-03-20 Insulinforbindelser

Publications (1)

Publication Number Publication Date
DK134189D0 true DK134189D0 (da) 1989-03-20

Family

ID=8103787

Family Applications (2)

Application Number Title Priority Date Filing Date
DK134189A DK134189D0 (da) 1989-03-20 1989-03-20 Insulinforbindelser
DK90905190.6T DK0463072T3 (da) 1989-03-20 1990-03-15 Hidtil ukendte insulinforbindelser

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK90905190.6T DK0463072T3 (da) 1989-03-20 1990-03-15 Hidtil ukendte insulinforbindelser

Country Status (23)

Country Link
US (1) US5430016A (ko)
EP (1) EP0463072B1 (ko)
JP (1) JPH04503808A (ko)
KR (1) KR920701250A (ko)
CN (1) CN1045793A (ko)
AT (1) ATE116661T1 (ko)
AU (1) AU637365B2 (ko)
CA (1) CA2049961A1 (ko)
DD (1) DD298788A5 (ko)
DE (1) DE69015811T2 (ko)
DK (2) DK134189D0 (ko)
ES (1) ES2068384T3 (ko)
FI (1) FI914419A0 (ko)
GR (1) GR1002545B (ko)
HU (1) HUT58349A (ko)
IE (1) IE66564B1 (ko)
IL (1) IL93792A0 (ko)
NO (1) NO300640B1 (ko)
NZ (1) NZ232953A (ko)
PT (1) PT93502B (ko)
WO (1) WO1990011299A1 (ko)
YU (1) YU53290A (ko)
ZA (1) ZA902086B (ko)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PH25772A (en) * 1985-08-30 1991-10-18 Novo Industri As Insulin analogues, process for their preparation
DE3844211A1 (de) * 1988-12-29 1990-07-05 Hoechst Ag Neue insulinderivate, verfahren zu deren herstellung, ihre verwendung und eine sie enthaltende pharmazeutische zubereitung
US5304473A (en) * 1991-06-11 1994-04-19 Eli Lilly And Company A-C-B proinsulin, method of manufacturing and using same, and intermediates in insulin production
NZ245170A (en) * 1991-11-26 1994-07-26 Lilly Co Eli Insulin and proinsulin analogues with arg at b31, b32 and ao and pharmaceutical compositions
US5948751A (en) * 1996-06-20 1999-09-07 Novo Nordisk A/S X14-mannitol
WO1999021573A1 (en) 1997-10-24 1999-05-06 Eli Lilly And Company Fatty acid-acylated insulin analogs
US6531448B1 (en) 1997-12-23 2003-03-11 Eli Lilly And Company Insoluble compositions for controlling blood glucose
US7378390B2 (en) * 1999-12-29 2008-05-27 Novo Nordisk A/S Method for making insulin precursors and insulin precursor analogues having improved fermentation yield in yeast
CA2468100A1 (en) * 2001-12-20 2003-07-03 Eli Lilly And Company Insulin molecule having protracted time action
EP1620465A2 (en) * 2003-04-29 2006-02-01 Eli Lilly And Company Insulin analogs having protracted time action
US9220837B2 (en) 2007-03-19 2015-12-29 Insuline Medical Ltd. Method and device for drug delivery
US20100292557A1 (en) * 2007-03-19 2010-11-18 Benny Pesach Method and device for substance measurement
US8622991B2 (en) 2007-03-19 2014-01-07 Insuline Medical Ltd. Method and device for drug delivery
EP2131900B1 (en) * 2007-03-19 2018-05-30 Insuline Medical Ltd. Drug delivery device
US8409133B2 (en) * 2007-12-18 2013-04-02 Insuline Medical Ltd. Drug delivery device with sensor for closed-loop operation
WO2009087082A2 (de) * 2008-01-09 2009-07-16 Sanofi-Aventis Deutschland Gmbh Neue insulinderivate mit extrem verzögertem zeit- / wirkungsprofil
CN102007143B (zh) 2008-01-09 2015-08-26 塞诺菲-安万特德国有限公司 具有超延迟时效特征的新型胰岛素衍生物
CN102256618A (zh) 2008-10-17 2011-11-23 赛诺菲-安万特德国有限公司 胰岛素和glp-1激动剂的组合
AU2009312474B2 (en) 2008-11-07 2014-12-04 Insuline Medical Ltd. Device and method for drug delivery
MY159565A (en) 2009-11-13 2017-01-13 Sanofi Aventis Deutschland Pharmaceutical composition comprising a glp-1 agonist and methionine
PT2554183T (pt) 2009-11-13 2018-07-09 Sanofi Aventis Deutschland Composição farmacêutica que compreende um agonista de glp-1, uma insulina e metionina
LT2611458T (lt) 2010-08-30 2016-12-27 Sanofi-Aventis Deutschland Gmbh Ave0010 panaudojimas gaminant vaistą, skirtą 2 tipo cukrinio diabeto gydymui
US9821032B2 (en) 2011-05-13 2017-11-21 Sanofi-Aventis Deutschland Gmbh Pharmaceutical combination for improving glycemic control as add-on therapy to basal insulin
WO2013030160A1 (en) 2011-08-29 2013-03-07 Sanofi-Aventis Deutschland Gmbh Pharmaceutical combination for use in glycemic control in diabetes type 2 patients
AR087744A1 (es) 2011-09-01 2014-04-16 Sanofi Aventis Deutschland Composicion farmaceutica para uso en el tratamiento de una enfermedad neurodegenerativa
WO2014178018A1 (en) 2013-05-02 2014-11-06 Glaxosmithkline Intellectual Property Development Limited Therapeutic peptides
CR20170314A (es) 2014-12-12 2017-10-20 Sanofi Aventis Deutschland Formulación de relación fija de insulina glargina/lixisenatida
TWI748945B (zh) 2015-03-13 2021-12-11 德商賽諾菲阿凡提斯德意志有限公司 第２型糖尿病病患治療
TW201705975A (zh) 2015-03-18 2017-02-16 賽諾菲阿凡提斯德意志有限公司 第２型糖尿病病患之治療
CN106323840A (zh) * 2016-09-13 2017-01-11 西南石油大学 一种页岩孔隙度测量方法
CN109735589B (zh) * 2019-01-02 2020-07-10 珠海冀百康生物科技有限公司 一种胰岛素DesB30的制备方法
CN113773398B (zh) * 2020-06-10 2023-05-23 宁波鲲鹏生物科技有限公司 一种德谷胰岛素衍生物及其应用

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55138393A (en) * 1979-04-13 1980-10-29 Shionogi & Co Ltd Semisynthesis of insulin
US4343898A (en) * 1980-02-11 1982-08-10 Novo Industri A/S Process for preparing esters of human insulin
DK147437A (en) * 1980-02-11 1900-01-01 Process for preparing human insulin or threonine B30 esters of human insulin, or a salt or complex thereof
DE3326473A1 (de) * 1983-07-22 1985-01-31 Hoechst Ag, 6230 Frankfurt Pharmazeutisches mittel zur behandlung des diabetes mellitus
DE3326472A1 (de) * 1983-07-22 1985-02-14 Hoechst Ag, 6230 Frankfurt Neue insulin-derivate, verfahren zu deren herstellung und deren verwendung sowie pharmazeutische mittel zur behandlung des diabetes mellitus
DE3327709A1 (de) * 1983-07-29 1985-02-07 Hoechst Ag, 6230 Frankfurt Insulin-derivat-kristallsuspensionen, verfahren zu deren herstellung und deren verwendung
DK58285D0 (da) * 1984-05-30 1985-02-08 Novo Industri As Peptider samt fremstilling og anvendelse deraf
US5008241A (en) * 1985-03-12 1991-04-16 Novo Nordisk A/S Novel insulin peptides
DK347086D0 (da) * 1986-07-21 1986-07-21 Novo Industri As Novel peptides
DK113585D0 (da) * 1985-03-12 1985-03-12 Novo Industri As Nye peptider
US4946828A (en) * 1985-03-12 1990-08-07 Novo Nordisk A/S Novel insulin peptides
DK119785D0 (da) * 1985-03-15 1985-03-15 Nordisk Gentofte Insulinpraeparat
DK129385A (da) * 1985-03-22 1986-09-23 Novo Industri As Peptider og fremstilling deraf
DK437786D0 (da) * 1986-09-12 1986-09-12 Nordisk Gentofte Insulinprecursorer
DE3717370A1 (de) * 1987-05-22 1988-12-01 Hoechst Ag Mischkristalle aus insulin und insulinderivaten, verfahren zur herstellung dieser mischkristalle, diese mischkristalle enthaltende pharmazeutische mittel und ihre verwendung zur behandlung von diabetes mellitus
DK336188D0 (da) * 1988-06-20 1988-06-20 Nordisk Gentofte Propeptider
DE3844211A1 (de) * 1988-12-29 1990-07-05 Hoechst Ag Neue insulinderivate, verfahren zu deren herstellung, ihre verwendung und eine sie enthaltende pharmazeutische zubereitung

Also Published As

Publication number Publication date
IE66564B1 (en) 1996-01-24
FI914419A0 (fi) 1991-09-19
IE901004L (en) 1990-09-20
CN1045793A (zh) 1990-10-03
AU637365B2 (en) 1993-05-27
NO913687D0 (no) 1991-09-19
DE69015811T2 (de) 1995-05-11
IL93792A0 (en) 1990-12-23
HUT58349A (en) 1992-02-28
CA2049961A1 (en) 1990-09-21
EP0463072A1 (en) 1992-01-02
AU5344890A (en) 1990-10-22
JPH04503808A (ja) 1992-07-09
NO300640B1 (no) 1997-06-30
PT93502B (pt) 1996-02-29
PT93502A (pt) 1990-11-07
YU53290A (sh) 1992-12-21
KR920701250A (ko) 1992-08-11
WO1990011299A1 (en) 1990-10-04
GR1002545B (el) 1997-01-28
DE69015811D1 (de) 1995-02-16
US5430016A (en) 1995-07-04
NO913687L (no) 1991-11-19
GR900100206A (el) 1991-07-31
HU902706D0 (en) 1991-12-30
ZA902086B (en) 1990-11-28
DK0463072T3 (da) 1995-06-12
DD298788A5 (de) 1992-03-12
ES2068384T3 (es) 1995-04-16
NZ232953A (en) 1992-10-28
EP0463072B1 (en) 1995-01-04
ATE116661T1 (de) 1995-01-15

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Legal Events

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PUP Patent expired