DK0463072T3 - Hidtil ukendte insulinforbindelser - Google Patents

Hidtil ukendte insulinforbindelser

Info

Publication number
DK0463072T3
DK0463072T3 DK90905190.6T DK90905190T DK0463072T3 DK 0463072 T3 DK0463072 T3 DK 0463072T3 DK 90905190 T DK90905190 T DK 90905190T DK 0463072 T3 DK0463072 T3 DK 0463072T3
Authority
DK
Denmark
Prior art keywords
insulin compounds
image
hitherto unknown
coded
amino acid
Prior art date
Application number
DK90905190.6T
Other languages
English (en)
Inventor
Per Balschmidt
Finn Benned Hansen
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Application granted granted Critical
Publication of DK0463072T3 publication Critical patent/DK0463072T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Toxicology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK90905190.6T 1989-03-20 1990-03-15 Hidtil ukendte insulinforbindelser DK0463072T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK134189A DK134189D0 (da) 1989-03-20 1989-03-20 Insulinforbindelser

Publications (1)

Publication Number Publication Date
DK0463072T3 true DK0463072T3 (da) 1995-06-12

Family

ID=8103787

Family Applications (2)

Application Number Title Priority Date Filing Date
DK134189A DK134189D0 (da) 1989-03-20 1989-03-20 Insulinforbindelser
DK90905190.6T DK0463072T3 (da) 1989-03-20 1990-03-15 Hidtil ukendte insulinforbindelser

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK134189A DK134189D0 (da) 1989-03-20 1989-03-20 Insulinforbindelser

Country Status (23)

Country Link
US (1) US5430016A (da)
EP (1) EP0463072B1 (da)
JP (1) JPH04503808A (da)
KR (1) KR920701250A (da)
CN (1) CN1045793A (da)
AT (1) ATE116661T1 (da)
AU (1) AU637365B2 (da)
CA (1) CA2049961A1 (da)
DD (1) DD298788A5 (da)
DE (1) DE69015811T2 (da)
DK (2) DK134189D0 (da)
ES (1) ES2068384T3 (da)
FI (1) FI914419A0 (da)
GR (1) GR1002545B (da)
HU (1) HUT58349A (da)
IE (1) IE66564B1 (da)
IL (1) IL93792A0 (da)
NO (1) NO300640B1 (da)
NZ (1) NZ232953A (da)
PT (1) PT93502B (da)
WO (1) WO1990011299A1 (da)
YU (1) YU53290A (da)
ZA (1) ZA902086B (da)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PH25772A (en) * 1985-08-30 1991-10-18 Novo Industri As Insulin analogues, process for their preparation
DE3844211A1 (de) * 1988-12-29 1990-07-05 Hoechst Ag Neue insulinderivate, verfahren zu deren herstellung, ihre verwendung und eine sie enthaltende pharmazeutische zubereitung
US5304473A (en) * 1991-06-11 1994-04-19 Eli Lilly And Company A-C-B proinsulin, method of manufacturing and using same, and intermediates in insulin production
TW224471B (da) * 1991-11-26 1994-06-01 Lilly Co Eli
US5948751A (en) * 1996-06-20 1999-09-07 Novo Nordisk A/S X14-mannitol
CA2306877A1 (en) 1997-10-24 1999-05-06 Eli Lilly And Company Insoluble insulin compositions
CO4970787A1 (es) 1997-12-23 2000-11-07 Lilly Co Eli Composiciones insolubles de insulina y derivados de insulina que controlan la glucosa sanguinea
US7378390B2 (en) * 1999-12-29 2008-05-27 Novo Nordisk A/S Method for making insulin precursors and insulin precursor analogues having improved fermentation yield in yeast
WO2003053339A2 (en) * 2001-12-20 2003-07-03 Eli Lilly And Company Insulin molecule having protracted time action
KR20050121748A (ko) * 2003-04-29 2005-12-27 일라이 릴리 앤드 캄파니 연장된 시간 작용을 갖는 인슐린 유사체
US8622991B2 (en) 2007-03-19 2014-01-07 Insuline Medical Ltd. Method and device for drug delivery
US9220837B2 (en) 2007-03-19 2015-12-29 Insuline Medical Ltd. Method and device for drug delivery
JP5731120B2 (ja) * 2007-03-19 2015-06-10 インスライン メディカル エルティーディー． 薬剤送達器具
US20100292557A1 (en) * 2007-03-19 2010-11-18 Benny Pesach Method and device for substance measurement
US8409133B2 (en) * 2007-12-18 2013-04-02 Insuline Medical Ltd. Drug delivery device with sensor for closed-loop operation
AU2009203810B2 (en) 2008-01-09 2013-07-25 Sanofi-Aventis Deutschland Gmbh Novel insulin derivatives having an extremely delayed time-action profile
DK2229407T3 (da) 2008-01-09 2017-02-27 Sanofi Aventis Deutschland Nye insulinderivater med ekstremt forsinket tids-/virkningsprofil
MX344293B (es) 2008-10-17 2016-12-13 Sanofi Aventis Deutschland Combinacion de una insulina y un agonista de glp-1.
CA2743027C (en) 2008-11-07 2016-04-12 Insuline Medical Ltd. Device and method for drug delivery
PT2498802E (pt) 2009-11-13 2015-04-13 Sanofi Aventis Deutschland Composição farmacêutica que compreende um agonista de glp-1, uma insulina e metionina
BR112012011403B8 (pt) 2009-11-13 2021-05-25 Sanofi Aventis Deutschland composição farmacêutica líquida compreendendo um agonista glp-1 e metionina e uso da mesma
RU2546520C2 (ru) 2010-08-30 2015-04-10 Санофи-Авентис Дойчланд Гмбх Применение ave0010 для производства лекарственного средства для лечения сахарного диабета 2 типа
US9821032B2 (en) 2011-05-13 2017-11-21 Sanofi-Aventis Deutschland Gmbh Pharmaceutical combination for improving glycemic control as add-on therapy to basal insulin
US9408893B2 (en) 2011-08-29 2016-08-09 Sanofi-Aventis Deutschland Gmbh Pharmaceutical combination for use in glycemic control in diabetes type 2 patients
TWI559929B (en) 2011-09-01 2016-12-01 Sanofi Aventis Deutschland Pharmaceutical composition for use in the treatment of a neurodegenerative disease
CA2909045C (en) 2013-05-02 2022-12-06 Glaxosmithkline Intellectual Property Development Limited Therapeutic peptides
LT3229828T (lt) 2014-12-12 2023-06-12 Sanofi-Aventis Deutschland Gmbh Insulino glargino/liksisenatido fiksuoto santykio kompozicija
TWI748945B (zh) 2015-03-13 2021-12-11 德商賽諾菲阿凡提斯德意志有限公司 第２型糖尿病病患治療
TW201705975A (zh) 2015-03-18 2017-02-16 賽諾菲阿凡提斯德意志有限公司 第２型糖尿病病患之治療
CN106323840A (zh) * 2016-09-13 2017-01-11 西南石油大学 一种页岩孔隙度测量方法
CN109735589B (zh) * 2019-01-02 2020-07-10 珠海冀百康生物科技有限公司 一种胰岛素DesB30的制备方法
CN113773398B (zh) * 2020-06-10 2023-05-23 宁波鲲鹏生物科技有限公司 一种德谷胰岛素衍生物及其应用

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55138393A (en) * 1979-04-13 1980-10-29 Shionogi & Co Ltd Semisynthesis of insulin
US4343898A (en) * 1980-02-11 1982-08-10 Novo Industri A/S Process for preparing esters of human insulin
DK147437A (en) * 1980-02-11 1900-01-01 Process for preparing human insulin or threonine B30 esters of human insulin, or a salt or complex thereof
DE3326472A1 (de) * 1983-07-22 1985-02-14 Hoechst Ag, 6230 Frankfurt Neue insulin-derivate, verfahren zu deren herstellung und deren verwendung sowie pharmazeutische mittel zur behandlung des diabetes mellitus
DE3326473A1 (de) * 1983-07-22 1985-01-31 Hoechst Ag, 6230 Frankfurt Pharmazeutisches mittel zur behandlung des diabetes mellitus
DE3327709A1 (de) * 1983-07-29 1985-02-07 Hoechst Ag, 6230 Frankfurt Insulin-derivat-kristallsuspensionen, verfahren zu deren herstellung und deren verwendung
DK58285D0 (da) * 1984-05-30 1985-02-08 Novo Industri As Peptider samt fremstilling og anvendelse deraf
US4946828A (en) * 1985-03-12 1990-08-07 Novo Nordisk A/S Novel insulin peptides
US5008241A (en) * 1985-03-12 1991-04-16 Novo Nordisk A/S Novel insulin peptides
DK347086D0 (da) * 1986-07-21 1986-07-21 Novo Industri As Novel peptides
DK113585D0 (da) * 1985-03-12 1985-03-12 Novo Industri As Nye peptider
DK119785D0 (da) * 1985-03-15 1985-03-15 Nordisk Gentofte Insulinpraeparat
DK129385A (da) * 1985-03-22 1986-09-23 Novo Industri As Peptider og fremstilling deraf
DK437786D0 (da) * 1986-09-12 1986-09-12 Nordisk Gentofte Insulinprecursorer
DE3717370A1 (de) * 1987-05-22 1988-12-01 Hoechst Ag Mischkristalle aus insulin und insulinderivaten, verfahren zur herstellung dieser mischkristalle, diese mischkristalle enthaltende pharmazeutische mittel und ihre verwendung zur behandlung von diabetes mellitus
DK336188D0 (da) * 1988-06-20 1988-06-20 Nordisk Gentofte Propeptider
DE3844211A1 (de) * 1988-12-29 1990-07-05 Hoechst Ag Neue insulinderivate, verfahren zu deren herstellung, ihre verwendung und eine sie enthaltende pharmazeutische zubereitung

Also Published As

Publication number Publication date
DE69015811T2 (de) 1995-05-11
KR920701250A (ko) 1992-08-11
ATE116661T1 (de) 1995-01-15
NO300640B1 (no) 1997-06-30
ZA902086B (en) 1990-11-28
NO913687L (no) 1991-11-19
DK134189D0 (da) 1989-03-20
HU902706D0 (en) 1991-12-30
EP0463072A1 (en) 1992-01-02
DE69015811D1 (de) 1995-02-16
GR1002545B (el) 1997-01-28
JPH04503808A (ja) 1992-07-09
IE66564B1 (en) 1996-01-24
EP0463072B1 (en) 1995-01-04
NZ232953A (en) 1992-10-28
GR900100206A (el) 1991-07-31
DD298788A5 (de) 1992-03-12
CN1045793A (zh) 1990-10-03
NO913687D0 (no) 1991-09-19
PT93502A (pt) 1990-11-07
CA2049961A1 (en) 1990-09-21
IE901004L (en) 1990-09-20
HUT58349A (en) 1992-02-28
US5430016A (en) 1995-07-04
FI914419A0 (fi) 1991-09-19
IL93792A0 (en) 1990-12-23
YU53290A (sh) 1992-12-21
WO1990011299A1 (en) 1990-10-04
ES2068384T3 (es) 1995-04-16
AU637365B2 (en) 1993-05-27
AU5344890A (en) 1990-10-22
PT93502B (pt) 1996-02-29

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