DK1326585T3 - Fremgangsmåde til fremstilling af pulverformuleringer - Google Patents

Fremgangsmåde til fremstilling af pulverformuleringer

Info

Publication number: DK1326585T3
Authority: DK; Denmark
Prior art keywords: preparation; powder formulations; formulations; powder
Prior art date: 2000-10-12

Application number

DK01986599T

Other languages

English (en)

Other versions

DK1326585T4 (da

Inventor

Michael Walz

Georg Boeck

Original Assignee

Boehringer Ingelheim Pharma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-10-12

Filing date

2001-10-09

Publication date

2006-05-22

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26007343&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1326585(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2001-08-10 Priority claimed from DE2001138022 external-priority patent/DE10138022A1/de

2001-10-09 Application filed by Boehringer Ingelheim Pharma filed Critical Boehringer Ingelheim Pharma

2006-05-22 Publication of DK1326585T3 publication Critical patent/DK1326585T3/da

2011-01-10 Application granted granted Critical

2011-01-10 Publication of DK1326585T4 publication Critical patent/DK1326585T4/da

Links

238000009472 formulation Methods 0.000 title 1
238000000034 method Methods 0.000 title 1
239000000203 mixture Substances 0.000 title 1
239000000843 powder Substances 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Epidemiology (AREA)
Pulmonology (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Otolaryngology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Detergent Compositions (AREA)
Cosmetics (AREA)

DK01986599.7T 2000-10-12 2001-10-09 Fremgangsmåde til fremstilling af pulverformuleringer DK1326585T4 (da)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
DE10050635		2000-10-12
DE2001138022 DE10138022A1 (de)	2001-08-10	2001-08-10	Verfahren zur Herstellung von Pulverformulierungen
PCT/EP2001/011636 WO2002030390A2 (de)	2000-10-12	2001-10-09	Verfahren zur herstellung von pulverformulierungen

Publications (2)

Publication Number	Publication Date
DK1326585T3 true DK1326585T3 (da)	2006-05-22
DK1326585T4 DK1326585T4 (da)	2011-01-10

Family

ID=26007343

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK01986599.7T DK1326585T4 (da)	2000-10-12	2001-10-09	Fremgangsmåde til fremstilling af pulverformuleringer

Country Status (40)

Country	Link
US (2)	US6585959B2 (da)
EP (1)	EP1326585B2 (da)
JP (2)	JP4986369B2 (da)
KR (1)	KR100849837B1 (da)
CN (1)	CN1269470C (da)
AR (1)	AR034166A1 (da)
AT (1)	ATE319422T1 (da)
AU (2)	AU1822002A (da)
BG (1)	BG66194B1 (da)
BR (1)	BR0114316A (da)
CA (1)	CA2425005C (da)
CY (1)	CY1105037T1 (da)
CZ (1)	CZ300022B6 (da)
DE (1)	DE50109178D1 (da)
DK (1)	DK1326585T4 (da)
EA (1)	EA004689B1 (da)
EE (1)	EE05146B1 (da)
EG (1)	EG24478A (da)
ES (1)	ES2259046T5 (da)
HK (1)	HK1060522A1 (da)
HR (1)	HRP20030277B1 (da)
HU (1)	HU229512B1 (da)
IL (2)	IL154919A0 (da)
ME (1)	ME02762B (da)
MX (1)	MXPA03003219A (da)
MY (1)	MY155912A (da)
NO (1)	NO333719B1 (da)
NZ (1)	NZ525781A (da)
PE (1)	PE20020424A1 (da)
PL (1)	PL204733B1 (da)
PT (1)	PT1326585E (da)
RS (1)	RS50495B (da)
SA (1)	SA01220518B1 (da)
SI (1)	SI1326585T2 (da)
SK (1)	SK285841B6 (da)
TW (1)	TWI283180B (da)
UA (1)	UA75375C2 (da)
UY (1)	UY26960A1 (da)
WO (1)	WO2002030390A2 (da)
ZA (1)	ZA200301349B (da)

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EP1397134A2 (en) *	2001-05-25	2004-03-17	Boehringer Ingelheim Pharma GmbH & Co.KG	Combination of a dopamine d2-receptor agonist and tiotropium or a derivative therof for treating obstructive airways
US20030070679A1 (en) *	2001-06-01	2003-04-17	Boehringer Ingelheim Pharma Kg	Capsules containing inhalable tiotropium
US20030008001A1 (en) *	2001-06-13	2003-01-09	Boehringer Ingelheim Pharma Kg	Process for cleaning hard gelatine capsules
US20030018019A1 (en) *	2001-06-23	2003-01-23	Boehringer Ingelheim Pharma Kg	Pharmaceutical compositions based on anticholinergics, corticosteroids and betamimetics
DE10141376A1 (de) *	2001-08-23	2003-03-13	Boehringer Ingelheim Pharma	Verfahren zur Herstellung von Inhalationspulvern
DE10141377A1 (de)	2001-08-23	2003-03-13	Boehringer Ingelheim Pharma	Aufstreuverfahren zur Herstellung von Pulverformulierungen
US7309707B2 (en) *	2002-03-20	2007-12-18	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Crystalline micronisate, process for the manufacture thereof and use thereof for the preparation of a medicament
US7244415B2 (en) *	2002-03-28	2007-07-17	Boehringer Ingelheim Pharma Gmbh & Co. Kg	HFA suspension formulations of an anhydrate
WO2003084509A1 (en) *	2002-04-04	2003-10-16	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Powder formulations suitable for inhalation
US20050158248A1 (en) *	2002-08-21	2005-07-21	Xian-Ming Zeng	Method of preparing dry powder inhalation compositions
GB0219513D0 (en)	2002-08-21	2002-10-02	Norton Healthcare Ltd	Inhalation compositions including coarse carrier
GB0219511D0 (en) *	2002-08-21	2002-10-02	Norton Healthcare Ltd	Method of preparing dry powder inhalation compositions
JP4744876B2 (ja) *	2002-08-21	2011-08-10	ノートン・ヘルスケアーリミテッド	乾燥粉末吸入組成物の製造方法
EA007377B1 (ru) *	2002-08-21	2006-10-27	Нортон Хелткэа Лтд.	Композиции для ингаляции
DE10255387A1 (de) *	2002-11-28	2004-06-09	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Neue Tiotropium-haltige Pulverformulierung für die Inhalation
US7763280B2 (en)	2002-11-28	2010-07-27	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Tiotropium containing powder formulation for inhalation
DE10351663A1 (de) *	2002-12-20	2004-07-01	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Pulverförmige Arzneimittel enthaltend ein Tiotropiumsalz und Salmeterolxinafoat
DE10317461A1 (de)	2003-04-16	2004-10-28	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Radioaktiv markierte Mikropartikel, Verfahren zu deren Herstellung und deren Verwendung
US20040226556A1 (en)	2003-05-13	2004-11-18	Deem Mark E.	Apparatus for treating asthma using neurotoxin
DE10331350A1 (de) *	2003-07-11	2005-01-27	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Pulverformulierungen für die Inhalation enthaltend ein neues Anticholinergikum
US7462367B2 (en)	2003-07-11	2008-12-09	Boehringer Ingelheim International Gmbh	Anticholinergic powder formulations for inhalation
WO2005020963A1 (en) *	2003-09-02	2005-03-10	Ivax Corporation	Process for preparing a medicament
GB0327723D0 (en) *	2003-09-15	2003-12-31	Vectura Ltd	Pharmaceutical compositions
RS20060293A (en)	2003-11-03	2008-08-07	Boehringer Ingelheim International Gmbh.,	Novel tiotropium salts, methods for the production thereof, and pharmaceutical formulations containing the same
SI2067779T1 (sl)	2003-11-03	2013-08-30	Boehringer Ingelheim International Gmbh	Tiotropijeve soli, postopek za njihovo pripravo in formulacije zdravil, ki jih vsebujejo
JP2007512898A (ja) *	2003-12-03	2007-05-24	マイクロドラッグアクチェンゲゼルシャフト	湿度に過敏な薬剤向けの予め計量されたドライパウダー吸入器
DE102004048389A1 (de)	2004-10-01	2006-04-06	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Modifizierung von Oberflächen von Laktose als Hilfsstoff zur Verwendung für Pulverinhalativa
WO2006086270A1 (en)	2005-02-10	2006-08-17	Glaxo Group Limited	Processes for making lactose utilizing pre-classification techniques and pharmaceutical formulations formed therefrom
GB0507835D0 (en) *	2005-04-18	2005-05-25	Solexa Ltd	Method and device for nucleic acid sequencing using a planar wave guide
DK1881980T3 (da)	2005-05-02	2012-10-01	Boehringer Ingelheim Int	Nye krystalline former af tiotropiumbromid
DE102005059602A1 (de)	2005-12-14	2007-06-21	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Verfahren zur Mikronisierung
ES2569359T3 (es)	2007-07-06	2016-05-10	Vectura Delivery Devices Limited	Inhalador
CN103691530A (zh) *	2007-07-27	2014-04-02	卡吉尔公司	多元醇的微粉化
EP2082768A1 (en)	2008-01-24	2009-07-29	Vectura Delivery Devices Limited	Inhaler
EP2082772A1 (en)	2008-01-24	2009-07-29	Vectura Delivery Devices Limited	Inhaler
EP2082766A1 (en)	2008-01-24	2009-07-29	Vectura Delivery Devices Limited	Blister Strip Coil Forming
EP2082767A1 (en)	2008-01-24	2009-07-29	Vectura Delivery Devices Limited	Inhaler
EP2082771A1 (en)	2008-01-24	2009-07-29	Vectura Delivery Devices Limited	Inhaler
US8483831B1 (en)	2008-02-15	2013-07-09	Holaira, Inc.	System and method for bronchial dilation
ES2398052T5 (es)	2008-05-09	2021-10-25	Nuvaira Inc	Sistemas para tratar un árbol bronquial
CN102119238B (zh) *	2008-07-24	2014-05-28	乔治洛德方法研究和开发液化空气有限公司	沉积含过渡金属的膜的方法
TWI491416B (zh)	2008-12-24	2015-07-11	Daiichi Sankyo Co Ltd	吸入用乾燥粉末醫藥組成物
GB0918450D0 (en)	2009-10-21	2009-12-09	Innovata Ltd	Composition
EP2926757B1 (en)	2009-10-27	2023-01-25	Nuvaira, Inc.	Delivery devices with coolable energy emitting assemblies
CN106618731B (zh)	2009-11-11	2020-08-07	努瓦拉公司	用于处理组织和控制狭窄的***、装置和方法
US8911439B2 (en)	2009-11-11	2014-12-16	Holaira, Inc.	Non-invasive and minimally invasive denervation methods and systems for performing the same
WO2011152804A2 (en)	2010-06-03	2011-12-08	Mahmut Bilgic	Process for dry powder formulations
TR201007251A2 (tr) *	2010-09-01	2012-03-21	Bi̇lgi̇ç Mahmut	Kalsiyum kanal blokörü formülasyonu.
US9398933B2 (en)	2012-12-27	2016-07-26	Holaira, Inc.	Methods for improving drug efficacy including a combination of drug administration and nerve modulation
TR201818680T4 (tr)	2014-07-09	2019-01-21	Arven Ilac Sanayi Ve Ticaret Anonim Sirketi	İnhalasyona yönelik formülasyonların hazırlanması için bir proses.
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2001
- 2001-09-10 UA UA2003054184A patent/UA75375C2/uk unknown
- 2001-10-09 DE DE50109178T patent/DE50109178D1/de not_active Expired - Lifetime
- 2001-10-09 PT PT01986599T patent/PT1326585E/pt unknown
- 2001-10-09 ME MEP-2008-427A patent/ME02762B/me unknown
- 2001-10-09 CZ CZ20031024A patent/CZ300022B6/cs not_active IP Right Cessation
- 2001-10-09 SK SK437-2003A patent/SK285841B6/sk not_active IP Right Cessation
- 2001-10-09 AT AT01986599T patent/ATE319422T1/de active
- 2001-10-09 ES ES01986599T patent/ES2259046T5/es not_active Expired - Lifetime
- 2001-10-09 EP EP01986599A patent/EP1326585B2/de not_active Expired - Lifetime
- 2001-10-09 PL PL362511A patent/PL204733B1/pl unknown
- 2001-10-09 SI SI200130509T patent/SI1326585T2/sl unknown
- 2001-10-09 WO PCT/EP2001/011636 patent/WO2002030390A2/de active IP Right Grant
- 2001-10-09 JP JP2002533833A patent/JP4986369B2/ja not_active Expired - Lifetime
- 2001-10-09 CN CNB01817146XA patent/CN1269470C/zh not_active Expired - Lifetime
- 2001-10-09 TW TW090124981A patent/TWI283180B/zh not_active IP Right Cessation
- 2001-10-09 KR KR1020037005039A patent/KR100849837B1/ko active IP Right Grant
- 2001-10-09 CA CA 2425005 patent/CA2425005C/en not_active Expired - Lifetime
- 2001-10-09 IL IL15491901A patent/IL154919A0/xx active IP Right Grant
- 2001-10-09 EE EEP200300170A patent/EE05146B1/xx unknown
- 2001-10-09 RS YUP-274/03A patent/RS50495B/sr unknown
- 2001-10-09 AU AU1822002A patent/AU1822002A/xx active Pending
- 2001-10-09 DK DK01986599.7T patent/DK1326585T4/da active
- 2001-10-09 MX MXPA03003219A patent/MXPA03003219A/es active IP Right Grant
- 2001-10-09 AU AU2002218220A patent/AU2002218220B2/en not_active Expired
- 2001-10-09 NZ NZ525781A patent/NZ525781A/en not_active IP Right Cessation
- 2001-10-09 HU HU0301268A patent/HU229512B1/hu unknown
- 2001-10-09 BR BR0114316-6A patent/BR0114316A/pt active Pending
- 2001-10-09 EA EA200300429A patent/EA004689B1/ru not_active IP Right Cessation
- 2001-10-10 PE PE2001001002A patent/PE20020424A1/es active IP Right Grant
- 2001-10-10 UY UY26960A patent/UY26960A1/es not_active IP Right Cessation
- 2001-10-10 EG EG2001101063A patent/EG24478A/xx active
- 2001-10-10 MY MYPI20014704A patent/MY155912A/en unknown
- 2001-10-11 US US09/977,911 patent/US6585959B2/en not_active Ceased
- 2001-10-12 AR ARP010104784A patent/AR034166A1/es active Pending
- 2001-11-11 SA SA01220518A patent/SA01220518B1/ar unknown
2003
- 2003-02-19 ZA ZA2003/01349A patent/ZA200301349B/en unknown
- 2003-03-13 IL IL154919A patent/IL154919A/en unknown
- 2003-03-26 BG BG107673A patent/BG66194B1/bg active Active
- 2003-04-10 HR HR20030277A patent/HRP20030277B1/xx not_active IP Right Cessation
- 2003-04-11 NO NO20031692A patent/NO333719B1/no not_active IP Right Cessation
2004
- 2004-01-28 US US10/766,748 patent/USRE38912E1/en not_active Expired - Lifetime
- 2004-05-20 HK HK04103581A patent/HK1060522A1/xx not_active IP Right Cessation
2006
- 2006-05-19 CY CY20061100654T patent/CY1105037T1/el unknown
2009
- 2009-06-08 JP JP2009136927A patent/JP2009197025A/ja active Pending

Also Published As

Publication number	Publication date
EE200300170A (et)	2003-06-16
IL154919A (en)	2011-01-31
AU1822002A (en)	2002-04-22
WO2002030390A3 (de)	2002-06-27
SK4372003A3 (en)	2003-07-01
EA200300429A1 (ru)	2003-10-30
BR0114316A (pt)	2003-08-26
CN1269470C (zh)	2006-08-16
UA75375C2 (en)	2006-04-17
HUP0301268A2 (hu)	2003-10-28
HUP0301268A3 (en)	2005-05-30
RS50495B (sr)	2010-03-02
JP2009197025A (ja)	2009-09-03
UY26960A1 (es)	2002-06-20
JP2004510806A (ja)	2004-04-08
EE05146B1 (et)	2009-04-15
ES2259046T3 (es)	2006-09-16
NO20031692L (no)	2003-06-06
BG107673A (bg)	2003-11-28
IL154919A0 (en)	2003-10-31
EP1326585B2 (de)	2010-09-29
BG66194B1 (bg)	2012-01-31
EP1326585A2 (de)	2003-07-16
CA2425005C (en)	2008-08-05
ZA200301349B (en)	2004-06-30
EP1326585B1 (de)	2006-03-08
HU229512B1 (en)	2014-01-28
NO333719B1 (no)	2013-09-02
DK1326585T4 (da)	2011-01-10
TWI283180B (en)	2007-07-01
CA2425005A1 (en)	2003-04-04
AR034166A1 (es)	2004-02-04
NZ525781A (en)	2004-11-26
EA004689B1 (ru)	2004-06-24
EG24478A (en)	2009-08-03
SI1326585T2 (sl)	2011-01-31
AU2002218220B2 (en)	2006-06-15
DE50109178D1 (de)	2006-05-04
ATE319422T1 (de)	2006-03-15
MXPA03003219A (es)	2004-12-03
US6585959B2 (en)	2003-07-01
PE20020424A1 (es)	2002-07-02
USRE38912E1 (en)	2005-12-06
CZ300022B6 (cs)	2009-01-14
JP4986369B2 (ja)	2012-07-25
HK1060522A1 (en)	2004-08-13
KR20030051706A (ko)	2003-06-25
CN1469733A (zh)	2004-01-21
SI1326585T1 (sl)	2006-06-30
MEP42708A (en)	2011-02-10
ME02762B (me)	2011-05-10
CY1105037T1 (el)	2010-03-03
SA01220518B1 (ar)	2006-12-10
YU27403A (sh)	2006-03-03
KR100849837B1 (ko)	2008-08-01
SK285841B6 (sk)	2007-09-06
HRP20030277A2 (en)	2005-02-28
NO20031692D0 (no)	2003-04-11
PT1326585E (pt)	2006-05-31
MY155912A (en)	2015-12-15
US20020106332A1 (en)	2002-08-08
HRP20030277B1 (en)	2011-09-30
WO2002030390A2 (de)	2002-04-18
PL204733B1 (pl)	2010-02-26
PL362511A1 (en)	2004-11-02
ES2259046T5 (es)	2011-02-28

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