DK1224180T3 - Substituerede azoler - Google Patents

Substituerede azoler

Info

Publication number: DK1224180T3
Authority: DK; Denmark
Prior art keywords: substituted azoles; azoles; substituted
Prior art date: 1999-04-14

Application number

DK00922630T

Other languages

English (en)

Inventor

Achim Schlapbach

Laszlo Revesz

Original Assignee

Novartis Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-04-14

Filing date

2000-04-12

Publication date

2003-10-20

1999-04-14 Priority claimed from GBGB9908531.8A external-priority patent/GB9908531D0/en

1999-04-14 Priority claimed from GBGB9908532.6A external-priority patent/GB9908532D0/en

2000-04-12 Application filed by Novartis Ag filed Critical Novartis Ag

2003-10-20 Application granted granted Critical

2003-10-20 Publication of DK1224180T3 publication Critical patent/DK1224180T3/da

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

DK00922630T 1999-04-14 2000-04-12 Substituerede azoler DK1224180T3 (da)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
GBGB9908531.8A GB9908531D0 (en)	1999-04-14	1999-04-14	Organic compounds
GBGB9908532.6A GB9908532D0 (en)	1999-04-14	1999-04-14	Organic compounds
PCT/EP2000/003290 WO2000063204A2 (en)	1999-04-14	2000-04-12	Substituted azoles

Publications (1)

Publication Number	Publication Date
DK1224180T3 true DK1224180T3 (da)	2003-10-20

Family

ID=26315413

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK00922630T DK1224180T3 (da)	1999-04-14	2000-04-12	Substituerede azoler

Country Status (25)

Country	Link
US (1)	US6579874B2 (da)
EP (1)	EP1224180B1 (da)
JP (1)	JP2003503311A (da)
KR (1)	KR20010108504A (da)
CN (1)	CN1378544A (da)
AR (1)	AR023465A1 (da)
AT (1)	ATE244236T1 (da)
AU (1)	AU4295300A (da)
BR (1)	BR0010598A (da)
CA (1)	CA2370417A1 (da)
CO (1)	CO5170501A1 (da)
CZ (1)	CZ20013696A3 (da)
DE (1)	DE60003709T2 (da)
DK (1)	DK1224180T3 (da)
ES (1)	ES2202114T3 (da)
HU (1)	HUP0302747A2 (da)
IL (1)	IL145836A0 (da)
MX (1)	MXPA01010434A (da)
NO (1)	NO20014987L (da)
PE (1)	PE20010031A1 (da)
PL (1)	PL364789A1 (da)
PT (1)	PT1224180E (da)
SK (1)	SK14562001A3 (da)
TR (1)	TR200102967T2 (da)
WO (1)	WO2000063204A2 (da)

Families Citing this family (55)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP2003511378A (ja)	1999-10-07	2003-03-25	アムジエン・インコーポレーテツド	トリアジン系キナーゼ阻害薬
EP1224185B1 (en) *	1999-10-27	2005-11-30	Novartis AG	Thiazole and imidazo[4,5-b]pyridine compounds and their pharmaceutical use
WO2001060816A1 (en) *	2000-02-17	2001-08-23	Amgen Inc.	Kinase inhibitors
ATE430742T1 (de)	2000-12-21	2009-05-15	Smithkline Beecham Corp	Pyrimidinamine als angiogenesemodulatoren
CA2436739A1 (en) *	2000-12-26	2002-07-04	Takeda Chemical Industries, Ltd.	Combination agent
CA2437248A1 (en)	2001-02-02	2002-08-15	Takeda Chemical Industries, Ltd.	Jnk inhibitor
BR0207957A (pt) *	2001-03-09	2004-02-25	Pfizer Prod Inc	Compostos antiinflamatórios de benzimidazol
AP2002002463A0 (en)	2001-03-09	2002-06-30	Pfizer Prod Inc	Novel triazolo-pyrimides anti-inflammatory compounds.
DE60205974T2 (de)	2001-04-04	2006-06-29	Pfizer Products Inc., Groton	Neue Benzotriazole mit entzündungshemmender Wirkung
WO2002100433A1 (en) *	2001-06-11	2002-12-19	Takeda Chemical Industries, Ltd.	Medicinal compositions
TWI231757B (en)	2001-09-21	2005-05-01	Solvay Pharm Bv	1H-Imidazole derivatives having CB1 agonistic, CB1 partial agonistic or CB1-antagonistic activity
US7109216B2 (en)	2001-09-21	2006-09-19	Solvay Pharmaceuticals B.V.	1H-imidazole derivatives having CB1 agonistic, CB1 partial agonistic or CB1-antagonistic activity
CA2456606C (en)	2001-09-21	2010-01-26	Solvay Pharmaceuticals B.V.	4,5-dihydro-1h-pyrazole derivatives having cb1-antagonistic activity
US7473695B2 (en) *	2001-10-22	2009-01-06	Mitsubishi Tanabe Pharma Corporation	4-imidazolin-2-one compounds
WO2003053922A2 (en) *	2001-12-19	2003-07-03	Merck & Co., Inc.	Heteroaryl substituted imidazole modulators of metabotropic glutamate receptor-5
AR039241A1 (es) *	2002-04-04	2005-02-16	Biogen Inc	Heteroarilos trisustituidos y metodos para su produccion y uso de los mismos
EP1534282B1 (en)	2002-07-09	2006-12-27	Boehringer Ingelheim Pharma GmbH & Co.KG	Pharmaceutical compositions of anticholinergics and p38 kinase inhibitors in the treatment of respiratory diseases
EP1529045A2 (en)	2002-08-09	2005-05-11	Astra Zeneca AB	New compounds
JP2006502134A (ja)	2002-08-09	2006-01-19	アストラゼネカアクチボラグ	代謝調節型グルタミン酸受容体において活性を有する化合物
KR20050039846A (ko) *	2002-08-09	2005-04-29	아스트라제네카 에이비이	메타보트로픽 글루타메이트 수용체-5의 조절제로서의옥사디아졸
US6949652B2 (en)	2002-08-30	2005-09-27	Pfizer, Inc.	Crystalline forms of 3-isopropyl-6-[4-(2,5-difluoro-phenyl)-oxazol-5-yl]-[1,2,4]triazolo-[4,3-A]pyridine
PA8579601A1 (es)	2002-08-30	2004-05-07	Pfizer Prod Inc	Compuestos antiinflamatorios de di y trifloruro-triazolo-piridinas
US7005523B2 (en)	2002-08-30	2006-02-28	Pfizer Inc.	Cycloalkyl-[4-(trifluorophenyl)-oxazol-5yl]-triazolo-pyridines
US7037923B2 (en)	2002-08-30	2006-05-02	Pfizer, Inc.	Alkyl-[4-(trifluorophenyl)-oxazol-5-yl]-triazolo-pyridines
US7012143B2 (en)	2002-08-30	2006-03-14	Dombroski Mark A	Cycloalkyl-[4-(difluorophenyl)-oxazol-5-yl]-triazolo-pyridines
JP2006508914A (ja) *	2002-08-30	2006-03-16	ファイザー・プロダクツ・インク	トリアゾロ−ピリジン製造のための新規な方法および中間体
UA80295C2 (en) *	2002-09-06	2007-09-10	Biogen Inc	Pyrazolopyridines and using the same
JP2006516548A (ja)	2002-12-30	2006-07-06	アンジオテックインターナショナルアクツィエンゲゼルシャフト	迅速ゲル化ポリマー組成物からの薬物送達法
ATE478859T1 (de)	2003-02-07	2010-09-15	Daiichi Sankyo Co Ltd	Pyrazolderivat
WO2004072072A1 (en)	2003-02-14	2004-08-26	Pfizer Products Inc.	Triazolo-pyridines as anti-inflammatory compounds
MY143245A (en) *	2004-04-28	2011-04-15	Mitsubishi Tanabe Pharma Corp	4- 2-(cycloalkylamino)pyrimidin-4-yl-(phenyl)-imidazolin-2-one derivatives as p38 map-kinase inhibitors for the treatment of inflammatory diseases
JP4803034B2 (ja)	2004-06-30	2011-10-26	Ｍｓｄ株式会社	ビアリール誘導体
US20060035893A1 (en)	2004-08-07	2006-02-16	Boehringer Ingelheim International Gmbh	Pharmaceutical compositions for treatment of respiratory and gastrointestinal disorders
PE20060777A1 (es)	2004-12-24	2006-10-06	Boehringer Ingelheim Int	Derivados de indolinona para el tratamiento o la prevencion de enfermedades fibroticas
EP1988825B1 (en) *	2006-02-08	2016-12-21	The General Hospital Corporation	Arrangements and systems for obtaining information associated with an anatomical sample using optical microscopy
ES2301380B1 (es)	2006-08-09	2009-06-08	Laboratorios Almirall S.A.	Nuevos derivados de 1,7-naftiridina.
ES2320955B1 (es)	2007-03-02	2010-03-16	Laboratorios Almirall S.A.	Nuevos derivados de 3-((1,2,4)triazolo(4,3-a)piridin-7-il)benzamida.
ES2329639B1 (es)	2007-04-26	2010-09-23	Laboratorios Almirall S.A.	Nuevos derivados de 4,8-difenilpoliazanaftaleno.
MX2009011754A (es) *	2007-04-30	2009-12-01	Abbott Lab	Inhibidores de enzima de diacilglicerol o-aciltransferasa tipo 1.
EP1992344A1 (en)	2007-05-18	2008-11-19	Institut Curie	P38 alpha as a therapeutic target in pathologies linked to FGFR3 mutation
EP2250160B1 (en)	2008-01-25	2015-11-11	Millennium Pharmaceuticals, Inc.	Thiophenes and their use as phosphatidylinositol 3-kinase (pi3k) inhibitors
EP2108641A1 (en)	2008-04-11	2009-10-14	Laboratorios Almirall, S.A.	New substituted spiro[cycloalkyl-1,3'-indo]-2'(1'H)-one derivatives and their use as p38 mitogen-activated kinase inhibitors
EP2113503A1 (en)	2008-04-28	2009-11-04	Laboratorios Almirall, S.A.	New substituted indolin-2-one derivatives and their use as p39 mitogen-activated kinase inhibitors
CA2750935A1 (en)	2009-01-30	2010-08-12	Millennium Pharmaceuticals, Inc.	Heteroaryls and their use as pi3k inhibitors
US8796314B2 (en)	2009-01-30	2014-08-05	Millennium Pharmaceuticals, Inc.	Heteroaryls and uses thereof
US9090601B2 (en)	2009-01-30	2015-07-28	Millennium Pharmaceuticals, Inc.	Thiazole derivatives
RU2011151603A (ru) *	2009-05-19	2013-06-27	ДАУ АГРОСАЙЕНСИЗ ЭлЭсСи	Соединения и способы борьбы с грибами
EP2322176A1 (en)	2009-11-11	2011-05-18	Almirall, S.A.	New 7-phenyl-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one derivatives
EP2603216A4 (en)	2010-08-11	2013-12-18	Millennium Pharm Inc	HETEROARYLE AND USES THEREOF
MA34797B1 (fr)	2010-08-11	2014-01-02	Millennium Pharm Inc	Hétéroaryles et leurs utilisations
US9062038B2 (en)	2010-08-11	2015-06-23	Millennium Pharmaceuticals, Inc.	Heteroaryls and uses thereof
EP2627181A4 (en)	2010-10-13	2014-03-19	Millennium Pharm Inc	HETEROARYLE AND USES THEREOF
AR086113A1 (es)	2011-04-30	2013-11-20	Abbott Lab	Isoxazolinas como agentes terapeuticos
US20190060286A1 (en)	2016-02-29	2019-02-28	University Of Florida Research Foundation, Incorpo	Chemotherapeutic Methods
JPWO2018159650A1 (ja) *	2017-02-28	2019-12-19	東レ株式会社	グアニジン誘導体及びその医薬用途

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE69433501T2 (de) *	1993-11-08	2004-11-04	Smithkline Beecham Corp.	Oxazole zur behandlung von zytokinvermittelten erkrankungen
US5739143A (en) *	1995-06-07	1998-04-14	Smithkline Beecham Corporation	Imidazole compounds and compositions
US5658903A (en) *	1995-06-07	1997-08-19	Smithkline Beecham Corporation	Imidazole compounds, compositions and use
JP3294616B2 (ja) *	1995-08-10	2002-06-24	メルクエンドカンパニーインコーポレーテッド	２−置換アリールピロール、このような化合物を含む組成物及び使用方法
US6492516B1 (en) *	1999-05-14	2002-12-10	Merck & Co., Inc.	Compounds having cytokine inhibitory activity

2000
- 2000-04-11 CO CO00026470A patent/CO5170501A1/es not_active Application Discontinuation
- 2000-04-12 BR BR0010598-8A patent/BR0010598A/pt not_active IP Right Cessation
- 2000-04-12 SK SK1456-2001A patent/SK14562001A3/sk unknown
- 2000-04-12 EP EP00922630A patent/EP1224180B1/en not_active Expired - Lifetime
- 2000-04-12 KR KR1020017013086A patent/KR20010108504A/ko not_active Application Discontinuation
- 2000-04-12 MX MXPA01010434A patent/MXPA01010434A/es unknown
- 2000-04-12 HU HU0302747A patent/HUP0302747A2/hu unknown
- 2000-04-12 AR ARP000101686A patent/AR023465A1/es unknown
- 2000-04-12 DK DK00922630T patent/DK1224180T3/da active
- 2000-04-12 CZ CZ20013696A patent/CZ20013696A3/cs unknown
- 2000-04-12 AT AT00922630T patent/ATE244236T1/de not_active IP Right Cessation
- 2000-04-12 CA CA002370417A patent/CA2370417A1/en not_active Abandoned
- 2000-04-12 IL IL14583600A patent/IL145836A0/xx unknown
- 2000-04-12 DE DE60003709T patent/DE60003709T2/de not_active Expired - Fee Related
- 2000-04-12 WO PCT/EP2000/003290 patent/WO2000063204A2/en not_active Application Discontinuation
- 2000-04-12 CN CN00807552A patent/CN1378544A/zh active Pending
- 2000-04-12 JP JP2000612294A patent/JP2003503311A/ja active Pending
- 2000-04-12 ES ES00922630T patent/ES2202114T3/es not_active Expired - Lifetime
- 2000-04-12 PL PL00364789A patent/PL364789A1/xx not_active Application Discontinuation
- 2000-04-12 AU AU42953/00A patent/AU4295300A/en not_active Abandoned
- 2000-04-12 PT PT00922630T patent/PT1224180E/pt unknown
- 2000-04-12 TR TR2001/02967T patent/TR200102967T2/xx unknown
- 2000-04-12 PE PE2000000337A patent/PE20010031A1/es not_active Application Discontinuation
2001
- 2001-10-12 US US09/975,913 patent/US6579874B2/en not_active Expired - Fee Related
- 2001-10-12 NO NO20014987A patent/NO20014987L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
BR0010598A (pt)	2002-02-05
US20020049220A1 (en)	2002-04-25
PL364789A1 (en)	2004-12-13
CZ20013696A3 (cs)	2002-02-13
EP1224180A2 (en)	2002-07-24
MXPA01010434A (es)	2002-03-27
CN1378544A (zh)	2002-11-06
CO5170501A1 (es)	2002-06-27
NO20014987L (no)	2001-12-14
SK14562001A3 (sk)	2002-03-05
DE60003709D1 (de)	2003-08-07
EP1224180B1 (en)	2003-07-02
NO20014987D0 (no)	2001-10-12
WO2000063204A3 (en)	2002-05-23
CA2370417A1 (en)	2000-10-26
ATE244236T1 (de)	2003-07-15
PT1224180E (pt)	2003-11-28
AR023465A1 (es)	2002-09-04
IL145836A0 (en)	2002-07-25
JP2003503311A (ja)	2003-01-28
ES2202114T3 (es)	2004-04-01
KR20010108504A (ko)	2001-12-07
DE60003709T2 (de)	2004-12-23
HUP0302747A2 (hu)	2003-12-29
AU4295300A (en)	2000-11-02
PE20010031A1 (es)	2001-02-23
WO2000063204A2 (en)	2000-10-26
TR200102967T2 (tr)	2002-01-21
US6579874B2 (en)	2003-06-17

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DK1224180T3 (da)	2003-10-20	Substituerede azoler
NO20016115L (no)	2002-02-12	Substituerte heterosykelkondenserte gamma-karbolin
EE200100502A (et)	2002-12-16	Ühendid
DE10084676T1 (de)	2003-04-30	Einmallanzettvorrichtung
ATA51899A (de)	2002-04-15	Handstempel
IS6662A (is)	2002-12-19	Imídasól afleiður
ATE360620T1 (de)	2007-05-15	Imidazolderivate
ATE357433T1 (de)	2007-04-15	4-pyrimidinyl-n-acyl-l-phenylanine
DK1070708T3 (da)	2004-05-10	Triazolderivater
ATE291575T1 (de)	2005-04-15	N-carbamoyloxyalkyl-substituierte azolium- verbindungen
ATE297895T1 (de)	2005-07-15	4-pyridinyl-n-acyl-l-phenylalanine
ID29533A (id)	2001-09-06	Senyawa-senyawa kalsilitik
NO20020466L (no)	2002-03-20	Kalsilytiske forbindelser
DE10085008T1 (de)	2002-10-10	Oberflächenbehandlungsdüse
NO20022927L (no)	2002-06-18	Substituerte pyrrazoler
NO20014262D0 (no)	2001-09-03	Tiazoloindolinon-forbindelser
ATE269311T1 (de)	2004-07-15	Benzoylpyridazine
DE10082008D2 (de)	2002-12-19	Ausbeulgerät
DK1200423T3 (da)	2003-12-22	Substituerede pehnyluraciler
ATE440824T1 (de)	2009-09-15	Nitro-sulfobenzamide
ATA107599A (de)	2002-06-15	Heizwasserbereiter
ID29984A (id)	2001-10-25	Senyawa-senyawa bis-stirilbifenil
DE10085167T1 (de)	2002-11-07	Gangumschalteinrichtung
ATA732000A (de)	2004-04-15	Kachelofen
DE10085144T1 (de)	2003-04-24	Polypeptidkomposition