ATE291575T1 - N-carbamoyloxyalkyl-substituierte azolium- verbindungen - Google Patents

N-carbamoyloxyalkyl-substituierte azolium- verbindungen

Info

Publication number
ATE291575T1
ATE291575T1 AT00992946T AT00992946T ATE291575T1 AT E291575 T1 ATE291575 T1 AT E291575T1 AT 00992946 T AT00992946 T AT 00992946T AT 00992946 T AT00992946 T AT 00992946T AT E291575 T1 ATE291575 T1 AT E291575T1
Authority
AT
Austria
Prior art keywords
carbamoyloxyalkyl
substituted
azolium compounds
compounds
substituted azolium
Prior art date
Application number
AT00992946T
Other languages
English (en)
Inventor
Hiroshi Fukuda
Tadakatsu Hayase
Eisaku Mizuguchi
Nobuo Shimma
Jun Ohwada
Nobuhiro Oikawa
Masahiro Sakaitani
Masao Tsukazaki
Isao Umeda
Original Assignee
Basilea Pharmaceutica Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basilea Pharmaceutica Ag filed Critical Basilea Pharmaceutica Ag
Application granted granted Critical
Publication of ATE291575T1 publication Critical patent/ATE291575T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
AT00992946T 1999-11-02 2000-10-25 N-carbamoyloxyalkyl-substituierte azolium- verbindungen ATE291575T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP99121694 1999-11-02
PCT/EP2000/010524 WO2001032652A2 (en) 1999-11-02 2000-10-25 N-substituted carbamoyloxyalkyl-azolium derivatives

Publications (1)

Publication Number Publication Date
ATE291575T1 true ATE291575T1 (de) 2005-04-15

Family

ID=8239312

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00992946T ATE291575T1 (de) 1999-11-02 2000-10-25 N-carbamoyloxyalkyl-substituierte azolium- verbindungen

Country Status (22)

Country Link
EP (1) EP1280795B1 (de)
JP (1) JP3787307B2 (de)
KR (1) KR100449797B1 (de)
CN (1) CN1185230C (de)
AR (1) AR029403A1 (de)
AT (1) ATE291575T1 (de)
AU (1) AU777859B2 (de)
BE (1) BE2016C007I2 (de)
BR (1) BRPI0015254C1 (de)
CA (2) CA2680292C (de)
CY (1) CY2016002I2 (de)
DE (1) DE60018989T2 (de)
DK (1) DK1280795T3 (de)
ES (1) ES2238341T3 (de)
FR (1) FR15C0096I2 (de)
LU (1) LU92939I2 (de)
MX (1) MXPA02004145A (de)
NL (1) NL300791I2 (de)
PT (1) PT1280795E (de)
TR (1) TR200201205T2 (de)
WO (1) WO2001032652A2 (de)
ZA (1) ZA200203003B (de)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY148805A (en) 2002-10-16 2013-05-31 Takeda Pharmaceutical Controlled release preparation
PL2192893T3 (pl) 2007-08-21 2015-12-31 Basilea Pharmaceutica Ag Kompozycja przeciwgrzybicza
CN103857440B (zh) 2011-06-22 2018-09-25 维奥姆生物科学有限公司 基于缀合物的抗真菌和抗细菌前药
CA2914583C (en) 2013-06-04 2019-06-18 Vyome Biosciences Pvt. Ltd. Coated particles and compositions comprising same
CN104230894B (zh) * 2013-06-06 2016-08-24 南京华威医药科技开发有限公司 ***类化合物
BR122019026066B1 (pt) * 2014-12-30 2022-01-18 Dow Agrosciences Llc Compostos de picolinamida
CN106032356B (zh) * 2015-03-13 2018-09-14 江苏正大丰海制药有限公司 一种[n-甲基-吡啶-2-基]氨基甲酸-1-氯乙酯的制备方法
CN104974143A (zh) * 2015-05-12 2015-10-14 深圳致君制药有限公司 一种季铵盐类化合物、其制备方法以及用途
CN106467519B (zh) * 2015-08-17 2019-08-13 南京华威医药科技集团有限公司 一种水溶性***化合物
CN106467534B (zh) * 2015-08-17 2019-10-11 江苏奥赛康药业有限公司 一种硫酸艾沙康唑鎓化合物及其药物组合物
CN106565699B (zh) * 2015-10-10 2019-07-26 江苏正大丰海制药有限公司 一种艾沙康唑硫酸盐晶体及其制备方法
WO2018067702A1 (en) 2016-10-04 2018-04-12 Massachusetts Institute Of Technology Bottlebrush copolymers and uses thereof
US11040958B2 (en) 2017-02-17 2021-06-22 Wuhan Ll Science And Technology Development Co., Ltd. Triazole antimicrobial derivative, pharmaceutical composition and use thereof
CN106916152B (zh) * 2017-04-27 2019-09-17 扬子江药业集团有限公司 氧化还原反应制备艾沙康唑鎓单硫酸盐的方法
WO2019006425A1 (en) 2017-06-30 2019-01-03 Massachusetts Institute Of Technology IMAGING AGENTS OF BRUSH ARRAY STAR POLYMERS AND USES THEREOF
US10716858B2 (en) 2017-06-30 2020-07-21 Massachusetts Institute Of Technology Branched multi-functional macromonomers and uses thereof
CN110317165A (zh) * 2018-03-28 2019-10-11 上海医药工业研究院 一种药物中间体2-甲胺基-3-吡啶甲醇的制备方法
CN110551064B (zh) * 2018-06-01 2021-01-01 重庆世森医药科技有限公司 艾沙康唑硫酸酯及其中间体的制备方法
SG11202100894XA (en) 2018-08-01 2021-02-25 Basilea Pharm Int Ag Methods for purifying isavuconazonium sulfate
WO2020037236A1 (en) 2018-08-17 2020-02-20 Massachusetts Institute Of Technology Degradable polymers of a cyclic silyl ether and uses thereof
CN110128420A (zh) * 2019-05-08 2019-08-16 阴启明 硫酸氢根/硫酸根型阴离子交换技术制备艾沙康唑鎓单硫酸盐的方法
EP4021576A1 (de) 2019-08-26 2022-07-06 Synthon B.V. Isavuconazoniumsalze und verfahren zur herstellung davon
CN114829447A (zh) * 2019-10-16 2022-07-29 麻省理工学院 刷前药及其用途
JP7454905B2 (ja) 2021-09-28 2024-03-25 旭化成ファーマ株式会社 有効成分であるイサブコナゾール又はそのプロドラッグを含有する真菌症治療及び／又は予防剤
JP2023049010A (ja) 2021-09-28 2023-04-07 旭化成ファーマ株式会社 エアベント付き輸液フィルタを備える点滴静脈投与用輸液セット
EP4289840A1 (de) 2022-06-07 2023-12-13 Zaklady Farmaceutyczne Polpharma S.A. Ein verfahren zur herstellung von isavuconazoniumsulfat

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998043970A1 (en) * 1997-03-31 1998-10-08 Takeda Chemical Industries, Ltd. Azole compounds, their production and their use
JP3108997B2 (ja) * 1997-03-31 2000-11-13 武田薬品工業株式会社 アゾール化合物、その製造法および用途
WO1999045008A1 (en) * 1998-03-06 1999-09-10 F. Hoffmann-La Roche Ag 3-[4-(4-cyanophenyl)thiazol-2-y)]-1-(1h-1,2,4-triazol-1-yl)-butan-2-ol derivatives having antifungal activity

Also Published As

Publication number Publication date
CA2680292C (en) 2012-11-27
CY2016002I1 (el) 2016-10-05
ES2238341T3 (es) 2005-09-01
TR200201205T2 (tr) 2002-08-21
AU2835201A (en) 2001-05-14
DE60018989T2 (de) 2005-08-18
KR20020062298A (ko) 2002-07-25
EP1280795A2 (de) 2003-02-05
NL300791I1 (de) 2016-03-15
CA2388320A1 (en) 2001-05-10
ZA200203003B (en) 2003-09-23
BRPI0015254B8 (pt) 2017-04-25
BR0015254B1 (pt) 2013-05-21
CA2388320C (en) 2009-12-15
JP2003513090A (ja) 2003-04-08
PT1280795E (pt) 2005-06-30
DE60018989D1 (de) 2005-04-28
CN1185230C (zh) 2005-01-19
CY2016002I2 (el) 2016-10-05
FR15C0096I2 (fr) 2016-04-22
JP3787307B2 (ja) 2006-06-21
CN1387529A (zh) 2002-12-25
AR029403A1 (es) 2003-06-25
EP1280795B1 (de) 2005-03-23
KR100449797B1 (ko) 2004-09-30
WO2001032652A2 (en) 2001-05-10
FR15C0096I1 (de) 2016-02-12
MXPA02004145A (es) 2002-10-17
NL300791I2 (de) 2016-03-15
BRPI0015254C1 (pt) 2021-05-25
LU92939I2 (fr) 2016-03-07
BR0015254A (pt) 2002-06-25
AU777859B2 (en) 2004-11-04
WO2001032652A3 (en) 2001-11-15
ES2238341T9 (es) 2016-03-02
DK1280795T3 (da) 2005-07-18
BE2016C007I2 (de) 2019-10-23
CA2680292A1 (en) 2001-05-10

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