DK0855397T3 - (R)-5-brom-N-(ethyl-4-methylhexahydro-1H-1,4-diazepin-6-yl)-2-methoxy-6-methylamino-3-pyridincarboxamid, fremgangsmåde til dets fremstilling og medicinsk præparat indeholdende denne forbindelse - Google Patents

(R)-5-brom-N-(ethyl-4-methylhexahydro-1H-1,4-diazepin-6-yl)-2-methoxy-6-methylamino-3-pyridincarboxamid, fremgangsmåde til dets fremstilling og medicinsk præparat indeholdende denne forbindelse

Info

Publication number: DK0855397T3
Authority: DK; Denmark
Prior art keywords: methylhexahydro; pyridinecarboxamide; diazepin; methylamino; bromo
Prior art date: 1995-07-28

Application number

DK96924189T

Other languages

Danish (da)

English (en)

Inventor

Shiro Kato

Toshiya Morie

Hiroshi Harada

Naoyuki Yoshida

Yoshimi Hirokawa

Original Assignee

Dainippon Pharmaceutical Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-07-28

Filing date

1996-07-23

Publication date

2001-06-25

1996-07-23 Application filed by Dainippon Pharmaceutical Co filed Critical Dainippon Pharmaceutical Co

2001-06-25 Application granted granted Critical

2001-06-25 Publication of DK0855397T3 publication Critical patent/DK0855397T3/da

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/08—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 not condensed with other rings
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

DK96924189T 1995-07-28 1996-07-23 (R)-5-brom-N-(ethyl-4-methylhexahydro-1H-1,4-diazepin-6-yl)-2-methoxy-6-methylamino-3-pyridincarboxamid, fremgangsmåde til dets fremstilling og medicinsk præparat indeholdende denne forbindelse DK0855397T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP07212495		1995-07-28
PCT/JP1996/002053 WO1997005129A1 (fr)	1995-07-28	1996-07-23	(r)-5-bromo-n-(1-ethyl-4-methylhexahydro-1h-1,4-diazepin-6-yl)-2-methoxy-6-methylamino-3-pyridine-carboxamide, son procede d'obtention et medicament le contenant

Publications (1)

Publication Number	Publication Date
DK0855397T3 true DK0855397T3 (da)	2001-06-25

Family

ID=16623612

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK96924189T DK0855397T3 (da)	1995-07-28	1996-07-23	(R)-5-brom-N-(ethyl-4-methylhexahydro-1H-1,4-diazepin-6-yl)-2-methoxy-6-methylamino-3-pyridincarboxamid, fremgangsmåde til dets fremstilling og medicinsk præparat indeholdende denne forbindelse

Country Status (25)

Country	Link
US (1)	US5945415A (pt)
EP (1)	EP0855397B1 (pt)
KR (1)	KR19990028395A (pt)
CN (1)	CN1096459C (pt)
AT (1)	ATE201021T1 (pt)
AU (1)	AU700635B2 (pt)
BR (1)	BR9609691A (pt)
CA (1)	CA2228056A1 (pt)
CZ (1)	CZ290442B6 (pt)
DE (1)	DE69612753T2 (pt)
DK (1)	DK0855397T3 (pt)
ES (1)	ES2156616T3 (pt)
GR (1)	GR3036089T3 (pt)
HK (1)	HK1018049A1 (pt)
HU (1)	HUP9901208A3 (pt)
IL (1)	IL122753A (pt)
MX (1)	MX9800620A (pt)
NO (1)	NO312964B1 (pt)
NZ (1)	NZ312799A (pt)
PL (1)	PL184073B1 (pt)
PT (1)	PT855397E (pt)
RU (1)	RU2156248C2 (pt)
SK (1)	SK282044B6 (pt)
TR (1)	TR199800165T1 (pt)
WO (1)	WO1997005129A1 (pt)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE19650778C2 (de) *	1996-12-06	2001-01-04	Asta Medica Ag	Verwendung von Dopaminrezeptor-Antagonisten in der palliativen Tumortherapie
GB0216027D0 (en) *	2002-07-10	2002-08-21	Arachnova Therapeutics Ltd	New therapeutic use
US20040048874A1 (en) *	2001-05-22	2004-03-11	Bardsley Hazel Judith	New therapeutic use of 4-(2-fluorophenyl)-6-methyl-2-(1-piperazinyl)thieno[2,3-D]pyrimidine
ITBO20020198A1 (it) *	2002-04-12	2003-10-13	Univ Bologna	Derivati 2 , 5 bis diammino 1 , 4 benzochenionici utili per il trattamento della malattia di alzheimer , metodo per la loro preparazione ed
EP2286817A3 (en) *	2003-01-13	2011-06-15	Edusa Pharmaceuticals, Inc	Method of treating functional bowel disorders
JP2006516977A (ja) *	2003-01-13	2006-07-13	ダイノゲンファーマシューティカルズ，インコーポレイテッド	悪心、嘔吐、レッチング、またはそれらの任意の組み合わせの治療方法
ES2290741T3 (es) *	2003-04-04	2008-02-16	Dynogen Pharmaceuticals Inc.	Metodo de tratamiento de trastornos del tracto urinario inferior.
US20060293309A1 (en) *	2005-03-28	2006-12-28	Dynogen Pharmaceuticals, Inc.	Method of treating disorders and conditions using peripherally-restricted antagonists and inhibitors
KR20120027111A (ko)	2009-03-31	2012-03-21	제리아 신야쿠 고교 가부시키 가이샤	1, 5－벤조디아제핀 유도체의 제조법
JP5858917B2 (ja)	2010-08-26	2016-02-10	興和株式会社	イソキノリン誘導体又はその塩の新規製造方法
ES2713686T3 (es) *	2014-02-03	2019-05-23	Mylan Laboratories Ltd	Procedimiento para la preparación de intermedios de Raltegravir

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5017573A (en) *	1988-07-29	1991-05-21	Dainippon Pharmaceutical Co., Ltd.	Indazole-3-carboxylic acid derivatives
US5166341A (en) *	1988-07-29	1992-11-24	Dainippon Pharmaceutical Co., Ltd.	6-amino-1,4-hexahydro-1H-diazepine derivatives
JPH04210970A (ja) *	1990-01-26	1992-08-03	Dainippon Pharmaceut Co Ltd	ベンズアミド誘導体及びその中間体
JPH03223265A (ja) *	1990-01-26	1991-10-02	Dainippon Pharmaceut Co Ltd	環状ジアミン誘導体
MX9206075A (es) *	1991-10-24	1993-04-01	Smithkline Beecham Plc	Nuevos compuestos antagonistas del receptor 5-hidroxitriptamina y composiciones farmaceuticas que los contienen

1996
- 1996-07-23 IL IL12275396A patent/IL122753A/xx not_active IP Right Cessation
- 1996-07-23 TR TR1998/00165T patent/TR199800165T1/xx unknown
- 1996-07-23 CZ CZ1998230A patent/CZ290442B6/cs not_active IP Right Cessation
- 1996-07-23 PT PT96924189T patent/PT855397E/pt unknown
- 1996-07-23 AU AU64717/96A patent/AU700635B2/en not_active Ceased
- 1996-07-23 BR BR9609691A patent/BR9609691A/pt not_active Application Discontinuation
- 1996-07-23 DK DK96924189T patent/DK0855397T3/da active
- 1996-07-23 HU HU9901208A patent/HUP9901208A3/hu unknown
- 1996-07-23 CA CA002228056A patent/CA2228056A1/en not_active Abandoned
- 1996-07-23 RU RU98103388/04A patent/RU2156248C2/ru not_active IP Right Cessation
- 1996-07-23 SK SK93-98A patent/SK282044B6/sk unknown
- 1996-07-23 CN CN96195988A patent/CN1096459C/zh not_active Expired - Fee Related
- 1996-07-23 WO PCT/JP1996/002053 patent/WO1997005129A1/ja not_active Application Discontinuation
- 1996-07-23 AT AT96924189T patent/ATE201021T1/de not_active IP Right Cessation
- 1996-07-23 DE DE69612753T patent/DE69612753T2/de not_active Expired - Fee Related
- 1996-07-23 PL PL96324749A patent/PL184073B1/pl unknown
- 1996-07-23 EP EP96924189A patent/EP0855397B1/en not_active Expired - Lifetime
- 1996-07-23 KR KR1019970709711A patent/KR19990028395A/ko not_active Application Discontinuation
- 1996-07-23 NZ NZ312799A patent/NZ312799A/en unknown
- 1996-07-23 ES ES96924189T patent/ES2156616T3/es not_active Expired - Lifetime
- 1996-07-23 US US09/000,468 patent/US5945415A/en not_active Expired - Fee Related
- 1996-07-23 MX MX9800620A patent/MX9800620A/es not_active IP Right Cessation
1998
- 1998-01-26 NO NO19980333A patent/NO312964B1/no not_active IP Right Cessation
- 1998-12-08 HK HK98112940A patent/HK1018049A1/xx not_active IP Right Cessation
2001
- 2001-06-19 GR GR20010400934T patent/GR3036089T3/el not_active IP Right Cessation

Also Published As

Publication number	Publication date
NO312964B1 (no)	2002-07-22
SK9398A3 (en)	1998-08-05
EP0855397B1 (en)	2001-05-09
CZ23098A3 (cs)	1998-06-17
PL184073B1 (pl)	2002-08-30
RU2156248C2 (ru)	2000-09-20
KR19990028395A (ko)	1999-04-15
WO1997005129A1 (fr)	1997-02-13
MX9800620A (es)	1998-04-30
NO980333D0 (no)	1998-01-26
CZ290442B6 (cs)	2002-07-17
NO980333L (no)	1998-03-23
EP0855397A1 (en)	1998-07-29
HUP9901208A3 (en)	2002-10-28
TR199800165T1 (xx)	1998-06-22
CN1096459C (zh)	2002-12-18
DE69612753T2 (de)	2005-07-07
DE69612753D1 (de)	2001-06-13
NZ312799A (en)	1999-04-29
CN1192213A (zh)	1998-09-02
BR9609691A (pt)	1999-03-23
ES2156616T3 (es)	2001-07-01
ATE201021T1 (de)	2001-05-15
EP0855397A4 (en)	1998-12-02
PT855397E (pt)	2001-08-30
CA2228056A1 (en)	1997-02-13
IL122753A0 (en)	1998-08-16
IL122753A (en)	2000-10-31
HUP9901208A2 (hu)	2000-04-28
PL324749A1 (en)	1998-06-08
AU700635B2 (en)	1999-01-07
AU6471796A (en)	1997-02-26
SK282044B6 (sk)	2001-10-08
GR3036089T3 (en)	2001-09-28
HK1018049A1 (en)	1999-12-10
US5945415A (en)	1999-08-31

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DK0855397T3 (da)	2001-06-25	(R)-5-brom-N-(ethyl-4-methylhexahydro-1H-1,4-diazepin-6-yl)-2-methoxy-6-methylamino-3-pyridincarboxamid, fremgangsmåde til dets fremstilling og medicinsk præparat indeholdende denne forbindelse
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