DK0593755T3 - Adenovirus, som er defekte m.h.t. replikation, og som udtrykker cytokiner, til antitumorbehandling - Google Patents

Adenovirus, som er defekte m.h.t. replikation, og som udtrykker cytokiner, til antitumorbehandling

Info

Publication number
DK0593755T3
DK0593755T3 DK93920562T DK93920562T DK0593755T3 DK 0593755 T3 DK0593755 T3 DK 0593755T3 DK 93920562 T DK93920562 T DK 93920562T DK 93920562 T DK93920562 T DK 93920562T DK 0593755 T3 DK0593755 T3 DK 0593755T3
Authority
DK
Denmark
Prior art keywords
replication
defective
adenovirus
regard
antitumor therapy
Prior art date
Application number
DK93920562T
Other languages
English (en)
Inventor
Hedi Haddada
Michel Perricaudet
Thierry Ragot
Original Assignee
Centre Nat Rech Scient
Roussy Inst Gustave
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centre Nat Rech Scient, Roussy Inst Gustave filed Critical Centre Nat Rech Scient
Application granted granted Critical
Publication of DK0593755T3 publication Critical patent/DK0593755T3/da

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/76—Viruses; Subviral particles; Bacteriophages
    • A61K35/761—Adenovirus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10211—Aviadenovirus, e.g. fowl adenovirus A
    • C12N2710/10241—Use of virus, viral particle or viral elements as a vector
    • C12N2710/10243—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10332—Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10341—Use of virus, viral particle or viral elements as a vector
    • C12N2710/10343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
DK93920562T 1992-03-16 1993-03-16 Adenovirus, som er defekte m.h.t. replikation, og som udtrykker cytokiner, til antitumorbehandling DK0593755T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9203120A FR2688514A1 (fr) 1992-03-16 1992-03-16 Adenovirus recombinants defectifs exprimant des cytokines et medicaments antitumoraux les contenant.
PCT/FR1993/000264 WO1993019191A1 (fr) 1992-03-16 1993-03-16 Adenovirus recombinants defectifs exprimant des cytokines pour traitement antitumoral

Publications (1)

Publication Number Publication Date
DK0593755T3 true DK0593755T3 (da) 2001-12-31

Family

ID=9427724

Family Applications (1)

Application Number Title Priority Date Filing Date
DK93920562T DK0593755T3 (da) 1992-03-16 1993-03-16 Adenovirus, som er defekte m.h.t. replikation, og som udtrykker cytokiner, til antitumorbehandling

Country Status (17)

Country Link
US (2) US6811774B2 (da)
EP (2) EP1138774A2 (da)
JP (1) JP3422995B2 (da)
AT (1) ATE205883T1 (da)
AU (1) AU672195B2 (da)
CA (1) CA2102302C (da)
DE (1) DE69330774T2 (da)
DK (1) DK0593755T3 (da)
ES (1) ES2164669T3 (da)
FI (1) FI935058A (da)
FR (1) FR2688514A1 (da)
HU (1) HU221275B1 (da)
NO (2) NO315454B1 (da)
NZ (1) NZ255950A (da)
PT (1) PT593755E (da)
SG (1) SG49002A1 (da)
WO (1) WO1993019191A1 (da)

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ATE205883T1 (de) 2001-10-15
EP0593755A1 (fr) 1994-04-27
WO1993019191A1 (fr) 1993-09-30
HU9303229D0 (en) 1994-03-28
US20020031499A1 (en) 2002-03-14
CA2102302A1 (fr) 1993-09-17
SG49002A1 (en) 1998-05-18
FR2688514B1 (da) 1994-12-30
NO20033523D0 (no) 2003-08-08
FI935058A0 (fi) 1993-11-16
FR2688514A1 (fr) 1993-09-17
NZ255950A (en) 1996-03-26
HU221275B1 (en) 2002-09-28
EP1138774A2 (fr) 2001-10-04
PT593755E (pt) 2002-03-28
DE69330774D1 (de) 2001-10-25
NO315454B1 (no) 2003-09-08
JP3422995B2 (ja) 2003-07-07
ES2164669T3 (es) 2002-03-01
US20050048031A1 (en) 2005-03-03
EP0593755B1 (fr) 2001-09-19
CA2102302C (fr) 2003-05-20
NO934061D0 (no) 1993-11-09
US7306793B2 (en) 2007-12-11
HUT66486A (en) 1994-11-28
AU3757093A (en) 1993-10-21
NO934061L (no) 1993-11-09
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FI935058A (fi) 1994-01-14
DE69330774T2 (de) 2002-07-04
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JPH06508039A (ja) 1994-09-14
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