DK0414297T3 - Effektiv fremstilling af mutantproteaser - Google Patents

Effektiv fremstilling af mutantproteaser

Info

Publication number
DK0414297T3
DK0414297T3 DK90202109.6T DK90202109T DK0414297T3 DK 0414297 T3 DK0414297 T3 DK 0414297T3 DK 90202109 T DK90202109 T DK 90202109T DK 0414297 T3 DK0414297 T3 DK 0414297T3
Authority
DK
Denmark
Prior art keywords
efficient production
mutant proteases
proteases
bacillus
mutant
Prior art date
Application number
DK90202109.6T
Other languages
English (en)
Inventor
Eekelen Christiaan Albertu Van
Der Laan Johannes Cornelis Van
Original Assignee
Genencor Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8202457&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0414297(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Genencor Int filed Critical Genencor Int
Application granted granted Critical
Publication of DK0414297T3 publication Critical patent/DK0414297T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
    • C12N9/54Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea bacteria being Bacillus
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52Genes encoding for enzymes or proenzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • C12N1/205Bacterial isolates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/75Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Bacillus
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/07Bacillus

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Detergent Compositions (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Mushroom Cultivation (AREA)
DK90202109.6T 1989-08-11 1990-08-02 Effektiv fremstilling af mutantproteaser DK0414297T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP89202117 1989-08-11

Publications (1)

Publication Number Publication Date
DK0414297T3 true DK0414297T3 (da) 1997-07-07

Family

ID=8202457

Family Applications (1)

Application Number Title Priority Date Filing Date
DK90202109.6T DK0414297T3 (da) 1989-08-11 1990-08-02 Effektiv fremstilling af mutantproteaser

Country Status (19)

Country Link
US (1) US20040014175A1 (da)
EP (1) EP0414297B1 (da)
JP (1) JP3490435B2 (da)
KR (1) KR0169978B1 (da)
CN (1) CN1049866A (da)
AT (1) ATE144283T1 (da)
AU (1) AU629970B2 (da)
BG (1) BG60567B1 (da)
BR (1) BR9003956A (da)
CA (1) CA2023094C (da)
DD (1) DD297187A5 (da)
DE (1) DE69028890T2 (da)
DK (1) DK0414297T3 (da)
ES (1) ES2095233T3 (da)
FI (1) FI110365B (da)
GR (1) GR3021669T3 (da)
IE (1) IE77037B1 (da)
PT (1) PT94961B (da)
RU (1) RU2060276C1 (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4304161A1 (de) * 1993-02-12 1994-08-25 Solvay Enzymes Gmbh & Co Kg Verbesserte hochalkalische Proteasen
DK0772684T3 (da) 1994-06-17 2005-12-12 Genencor Int Amylolytiske enzymer afledt fra B. Licheniformis alpha-amylasen med forbedrede karakteristika
DK0894126T3 (da) * 1996-03-27 2006-06-12 Novozymes As Alkalisk phosphatase-deficient trådformet svamp
JP3440694B2 (ja) * 1996-05-16 2003-08-25 ライオン株式会社 口腔用組成物
GB0024554D0 (en) 2000-10-06 2000-11-22 Agrol Ltd Ethanol production
US8124399B2 (en) * 2002-03-29 2012-02-28 Danisco Us Inc. Enhanced protein expression in Bacillus
WO2006088972A2 (en) 2005-02-16 2006-08-24 The General Hospital Corporation Use of modulatirs of compounds of tgf-beta superfamily to regulate hepcidin-mediated iron metabolism
RU2511416C1 (ru) * 2012-10-24 2014-04-10 Федеральное государственное автономное образовательное учреждение высшего профессионального образования "Казанский (Приволжский) федеральный университет" (ФГАО ВПО КФУ) Штамм бактерий bacillus pumilus 2a-5 с низкой протеолитической активностью, повышенной активностью фосфатазы, способ его получения и применения
RU2510821C1 (ru) * 2012-10-24 2014-04-10 Федеральное государственное автономное образовательное учреждение высшего профессионального образования "Казанский (Приволжский) Федеральный Университет" (ФГАОУ ВПО КФУ) Штамм бактерий bacillus pumilus мк-10 с низкой протеолитической активностью и его применение

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1234445A (da) * 1967-10-03 1971-06-03
JPS6055118B2 (ja) * 1982-02-08 1985-12-03 昭和電工株式会社 新規な細菌アルカリプロテア−ゼ及びその製造方法
NZ208612A (en) * 1983-06-24 1991-09-25 Genentech Inc Method of producing "procaryotic carbonyl hydrolases" containing predetermined, site specific mutations
US4828994A (en) * 1984-09-21 1989-05-09 Genex Corporation Bacillus strains with reduced extracellular protease levels
AU620326B2 (en) * 1987-02-27 1992-02-20 Dsm Ip Assets B.V. Stable gene amplification in chromosomal dna of prokaryotic microorganisms
EP0479396B1 (en) * 1987-02-27 1999-06-09 Genencor International, Inc. Transformation of alkalophilic bacillus strains
CN1056187C (zh) * 1988-02-11 2000-09-06 金克克国际有限公司 新的蛋白水解酶及其在洗涤剂中的应用

Also Published As

Publication number Publication date
US20040014175A1 (en) 2004-01-22
CA2023094A1 (en) 1991-02-12
BG92653A (bg) 1993-12-24
CA2023094C (en) 2000-03-28
JPH03210177A (ja) 1991-09-13
PT94961A (pt) 1991-04-18
RU2060276C1 (ru) 1996-05-20
DD297187A5 (de) 1992-01-02
IE77037B1 (en) 1997-11-19
FI110365B (fi) 2002-12-31
KR0169978B1 (ko) 1999-02-01
IE902904A1 (en) 1991-02-27
EP0414297B1 (en) 1996-10-16
BG60567B1 (bg) 1995-08-28
PT94961B (pt) 1997-05-28
GR3021669T3 (en) 1997-02-28
CN1049866A (zh) 1991-03-13
EP0414297A1 (en) 1991-02-27
ES2095233T3 (es) 1997-02-16
JP3490435B2 (ja) 2004-01-26
KR910004805A (ko) 1991-03-29
AU629970B2 (en) 1992-10-15
FI903927A0 (fi) 1990-08-08
DE69028890T2 (de) 1997-02-27
DE69028890D1 (de) 1996-11-21
AU6096190A (en) 1991-02-14
BR9003956A (pt) 1991-09-03
ATE144283T1 (de) 1996-11-15

Similar Documents

Publication Publication Date Title
FI892114A0 (fi) Foerfarande foer framstaellning av polypeptider.
DK0902777T3 (da) D-Mannitol og dets fremstilling
DK0414297T3 (da) Effektiv fremstilling af mutantproteaser
AU6794994A (en) New alkaline serine protease of paecilomyces lilacinus
ES2196019T3 (es) Proteasa fungica.
IT1250692B (it) Procedimento per la preparazione di demetilepipodofillotossina- beta-d-glucosidi.
FI931634A0 (fi) Nytt svampproteas
DE69737457D1 (de) O-fukosyltransferase
DK585784A (da) Bacillus subtilis dsm 2704 og fremgangsmaade til fremstilling af alfa-amylase
DE69942984D1 (de) Ien und ihre verwendungen
ZA846388B (en) Alpha-allenic-alpha-amino acids
ATE89741T1 (de) Thrombolytisch wirkendes kombinationspraeparat.
ZA91752B (en) Process for the enzymatic cleavage or recombinant proteins using iga proteases
ES2113928T3 (es) Nuevos microorganismos y un procedimiento para preparar acido 3-alfa,7-alfa-dihidroxi-12-ceto-5-beta-colanico.
NO874143D0 (no) Fremgangsmaate for fremstilling av trombolytiske midler.
SU1826520A1 (ru) Штамм бактерий bacillus polymyxa - продуцент полисахарида
DK0717778T3 (da) Höjalkalisk serinprotease