DE69802100D1 - 1,2,4-triazolo[4,3-b]pyrido[3,2-d]pyridazinderivate und diese enthaltende pharmaceutische zubereitungen - Google Patents

1,2,4-triazolo[4,3-b]pyrido[3,2-d]pyridazinderivate und diese enthaltende pharmaceutische zubereitungen

Info

Publication number
DE69802100D1
DE69802100D1 DE69802100T DE69802100T DE69802100D1 DE 69802100 D1 DE69802100 D1 DE 69802100D1 DE 69802100 T DE69802100 T DE 69802100T DE 69802100 T DE69802100 T DE 69802100T DE 69802100 D1 DE69802100 D1 DE 69802100D1
Authority
DE
Germany
Prior art keywords
triazolo
pyrido
pharmaceutical preparations
preparations containing
pyridazine derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69802100T
Other languages
English (en)
Other versions
DE69802100T2 (de
Inventor
Ferrer Jordi Gracia
Crespo M Isabel Crespo
Noverola Armando Vega
Garcia Andres Fernandez
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Almirall SA
Original Assignee
Almirall Prodesfarma SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Almirall Prodesfarma SA filed Critical Almirall Prodesfarma SA
Publication of DE69802100D1 publication Critical patent/DE69802100D1/de
Application granted granted Critical
Publication of DE69802100T2 publication Critical patent/DE69802100T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/14—Decongestants or antiallergics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Immunology (AREA)
  • Cardiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE69802100T 1997-07-29 1998-07-13 1,2,4-triazolo[4,3-b]pyrido[3,2-d]pyridazinderivate und diese enthaltende pharmaceutische zubereitungen Expired - Fee Related DE69802100T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ES009701670A ES2137113B1 (es) 1997-07-29 1997-07-29 Nuevos derivados de triazolo-piridazinas heterociclicos.
PCT/EP1998/004340 WO1999006404A1 (en) 1997-07-29 1998-07-13 1,2,4-triazolo[4,3-b]pyrido[3,2-d]pyridazine derivatives and pharmaceutical compositions containing them

Publications (2)

Publication Number Publication Date
DE69802100D1 true DE69802100D1 (de) 2001-11-22
DE69802100T2 DE69802100T2 (de) 2002-03-14

Family

ID=8300216

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69802100T Expired - Fee Related DE69802100T2 (de) 1997-07-29 1998-07-13 1,2,4-triazolo[4,3-b]pyrido[3,2-d]pyridazinderivate und diese enthaltende pharmaceutische zubereitungen

Country Status (36)

Country Link
US (2) US6407108B1 (de)
EP (1) EP1001955B1 (de)
JP (1) JP4320118B2 (de)
KR (1) KR20010022353A (de)
CN (1) CN1135231C (de)
AR (1) AR015927A1 (de)
AT (1) ATE207069T1 (de)
AU (1) AU737709B2 (de)
BG (1) BG64448B1 (de)
BR (1) BR9810829B1 (de)
CA (1) CA2298935A1 (de)
CO (1) CO4970780A1 (de)
CZ (1) CZ290208B6 (de)
DE (1) DE69802100T2 (de)
DK (1) DK1001955T3 (de)
EE (1) EE04313B1 (de)
EG (1) EG24041A (de)
ES (2) ES2137113B1 (de)
HK (1) HK1024914A1 (de)
HU (1) HUP0004708A3 (de)
ID (1) ID24506A (de)
IL (1) IL134081A (de)
MY (1) MY118796A (de)
NO (1) NO315118B1 (de)
NZ (1) NZ502356A (de)
PE (1) PE111099A1 (de)
PL (1) PL191031B1 (de)
PT (1) PT1001955E (de)
RU (1) RU2202552C2 (de)
SI (1) SI1001955T1 (de)
SK (1) SK284046B6 (de)
TR (1) TR200000243T2 (de)
TW (1) TW542837B (de)
UA (1) UA60339C2 (de)
WO (1) WO1999006404A1 (de)
ZA (1) ZA986248B (de)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2792938B1 (fr) * 1999-04-28 2001-07-06 Warner Lambert Co NOUVELLES 1-AMINO TRIAZOLO [4,3-a] QUINAZOLINE-5-ONES INHIBITRICES DE PHOSPHODIESTERASES IV
KR100701904B1 (ko) 1999-08-21 2007-04-02 알타나 파마 아게 Ｐｄｅ 억제제 및 베타 2 아드레날린수용체 작동제의상승적 조합
WO2002080974A1 (fr) * 2001-04-04 2002-10-17 Sankyo Company, Limited Utilisation medicale d'inhibiteur de production de cytokine
AU2002337105B2 (en) * 2001-09-19 2008-03-20 Takeda Gmbh Combination of a NSAID and a PDE-4 inhibitor
FR2832711B1 (fr) * 2001-11-26 2004-01-30 Warner Lambert Co Derives de triazolo [4,3-a] pyrido [2,3-d] pyrimidin-5-ones, compositions les contenant, procede de preparation et utilisation
KR101064227B1 (ko) * 2002-11-06 2011-09-14 아스카 세이야쿠 가부시키가이샤 피라졸로나프티리딘 유도체
ES2211344B1 (es) 2002-12-26 2005-10-01 Almirall Prodesfarma, S.A. Nuevos derivados de piridazin-3(2h)-ona.
US20050187278A1 (en) * 2003-08-28 2005-08-25 Pharmacia Corporation Treatment or prevention of vascular disorders with Cox-2 inhibitors in combination with cyclic AMP-specific phosphodiesterase inhibitors
RU2246496C1 (ru) * 2003-09-12 2005-02-20 Тец Виктор Вениаминович Вещество с противовирусной и антибактериальной активностью на основе производных 2,8-дитиоксо-1h-пирано[2,3-d, 6,5-d`] дипиримидина и их 10-аза-аналогов
ES2251866B1 (es) 2004-06-18 2007-06-16 Laboratorios Almirall S.A. Nuevos derivados de piridazin-3(2h)-ona.
PT1898903E (pt) * 2005-06-10 2013-06-28 Merck Sharp & Dohme Inibidores da atividade de akt
EP2258359A3 (de) 2005-08-26 2011-04-06 Braincells, Inc. Neurogenese durch Modulation des Muscarinrezeptors mit Sabcomelin
CA2620333A1 (en) 2005-08-26 2007-03-01 Braincells, Inc. Neurogenesis by muscarinic receptor modulation
CA2622605A1 (en) * 2005-09-15 2007-03-22 Aska Pharmaceutical Co., Ltd. Heterocycle compound, and production process and application thereof
EP2377530A3 (de) 2005-10-21 2012-06-20 Braincells, Inc. Modulation von Neurogenese durch PDE-Hemmung
WO2007053596A1 (en) 2005-10-31 2007-05-10 Braincells, Inc. Gaba receptor mediated modulation of neurogenesis
US20100216734A1 (en) 2006-03-08 2010-08-26 Braincells, Inc. Modulation of neurogenesis by nootropic agents
EP2026813A2 (de) 2006-05-09 2009-02-25 Braincells, Inc. 5-ht-rezeptor-vermittelte neurogenese
JP2009536669A (ja) 2006-05-09 2009-10-15 ブレインセルス，インコーポレイティド アンジオテンシン調節による神経新生
WO2008021781A1 (en) 2006-08-07 2008-02-21 Incyte Corporation Triazolotriazines as kinase inhibitors
KR20090064418A (ko) 2006-09-08 2009-06-18 브레인셀즈 인코퍼레이션 4-아실아미노피리딘 유도체 포함 조합물
US20100184806A1 (en) 2006-09-19 2010-07-22 Braincells, Inc. Modulation of neurogenesis by ppar agents
HUE026659T2 (en) 2006-11-22 2016-07-28 Incyte Holdings Corp Imidazotriazines and imidazopyrimidines as kinase inhibitors
US20110112079A1 (en) * 2008-01-09 2011-05-12 Thomas Craig J Phosphodiesterase inhibitors
SI2300455T1 (sl) 2008-05-21 2017-12-29 Incyte Holdings Corporation Soli 2-fluoro-n-metil-4-(7-(kinolin-6-il-metil)-imidazo(1,2-b)1,2,4) triazin-2-il)benzamid in postopki v zvezi z njihovo pripravo
EP2196465A1 (de) 2008-12-15 2010-06-16 Almirall, S.A. (3-oxo)pyridazin-4-ylurea-Derivate als PDE4 Hemmern
US20100216805A1 (en) 2009-02-25 2010-08-26 Braincells, Inc. Modulation of neurogenesis using d-cycloserine combinations
EP2226323A1 (de) 2009-02-27 2010-09-08 Almirall, S.A. Neuartige Tetrahydropyrazol[3,4-c]isochinolin-5-amin-Derivate
KR20120111739A (ko) 2009-12-31 2012-10-10 센트로 내셔널 드 인베스티가시오네스 온콜로지카스 (씨엔아이오) 키나제 억제제로서의 사용을 위한 삼환식 화합물
AU2011269788B2 (en) 2010-02-03 2015-12-10 Incyte Holdings Corporation Imidazo[1,2-b][1,2,4]triazines as c-Met inhibitors
EP2380890A1 (de) 2010-04-23 2011-10-26 Almirall, S.A. Neue 7,8-Dihydro-1,6-Naphthyridin-5(6H)-on-Derivate als PDE4 Inhibitoren
EP2394998A1 (de) 2010-05-31 2011-12-14 Almirall, S.A. 3-(5-Amino-6-oxo-1,6-dihydropyridazin-3-yl)-biphenyl Derivate als PDE4 Inhibitoren
WO2012098387A1 (en) 2011-01-18 2012-07-26 Centro Nacional De Investigaciones Oncológicas (Cnio) 6, 7-ring-fused triazolo [4, 3 - b] pyridazine derivatives as pim inhibitors
WO2013004984A1 (en) 2011-07-07 2013-01-10 Centro Nacional De Investigaciones Oncologicas (Cnio) Tricyclic compounds for use as kinase inhibitors
WO2013005041A1 (en) 2011-07-07 2013-01-10 Centro Nacional De Investigaciones Oncológicas (Cnio) Tricyclic heterocyclic compounds as kinase inhibitors
WO2013005057A1 (en) 2011-07-07 2013-01-10 Centro Nacional De Investigaciones Oncológicas (Cnio) New compounds
US20150119399A1 (en) 2012-01-10 2015-04-30 President And Fellows Of Harvard College Beta-cell replication promoting compounds and methods of their use

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3122670A1 (de) 1981-06-06 1982-12-23 Dr. Karl Thomae Gmbh, 7950 Biberach "neue 1,4,9,10-tetrahydro-pyrazolo(4,3-e) pyrido(3,2-b)(1,4)diazepin-10-one, verfahren zu ihrer herstellung und ihre verwendung zur herstellung von pharmazeutischen wirkstoffen"
FI81350C (fi) * 1982-01-18 1990-10-10 Lepetit Spa Analogfoerfarande foer framstaellning av nya, farmakologiskt aktiva 6-substituerade s-triatsolo/3,4-a/ ftalazinderivat.
JP3120857B2 (ja) * 1990-02-19 2000-12-25 中外製薬株式会社 新規な縮合複素環化合物とこれを用いた抗喘息剤
TW365606B (en) * 1991-10-09 1999-08-01 Syntex Inc Pyrido pyridazinone and pyridazinthione compounds
GB9514465D0 (en) 1995-07-14 1995-09-13 Glaxo Lab Sa Chemical compounds

Also Published As

Publication number Publication date
UA60339C2 (uk) 2003-10-15
PT1001955E (pt) 2002-02-28
CZ2000333A3 (cs) 2000-05-17
NO315118B1 (no) 2003-07-14
CO4970780A1 (es) 2000-11-07
TR200000243T2 (tr) 2000-07-21
ES2137113A1 (es) 1999-12-01
BR9810829A (pt) 2000-07-25
HK1024914A1 (en) 2000-10-27
NZ502356A (en) 2001-03-30
DE69802100T2 (de) 2002-03-14
ZA986248B (en) 1999-02-05
CA2298935A1 (en) 1999-02-11
SI1001955T1 (en) 2002-02-28
ATE207069T1 (de) 2001-11-15
EP1001955A1 (de) 2000-05-24
US6407108B1 (en) 2002-06-18
US20020183326A1 (en) 2002-12-05
PL191031B1 (pl) 2006-03-31
PE111099A1 (es) 1999-11-18
SK284046B6 (sk) 2004-08-03
JP2001512121A (ja) 2001-08-21
JP4320118B2 (ja) 2009-08-26
EG24041A (en) 2008-04-03
IL134081A (en) 2004-02-08
HUP0004708A2 (hu) 2001-07-30
WO1999006404A1 (en) 1999-02-11
TW542837B (en) 2003-07-21
AU8861298A (en) 1999-02-22
EE200000052A (et) 2000-10-16
DK1001955T3 (da) 2001-11-19
NO20000394D0 (no) 2000-01-26
KR20010022353A (ko) 2001-03-15
AU737709B2 (en) 2001-08-30
CN1135231C (zh) 2004-01-21
BG104112A (en) 2001-01-31
IL134081A0 (en) 2001-04-30
EE04313B1 (et) 2004-06-15
ES2162466T3 (es) 2001-12-16
HUP0004708A3 (en) 2002-11-28
CN1266434A (zh) 2000-09-13
BR9810829B1 (pt) 2009-08-11
RU2202552C2 (ru) 2003-04-20
ES2137113B1 (es) 2000-09-16
BG64448B1 (en) 2005-02-28
NO20000394L (no) 2000-03-27
AR015927A1 (es) 2001-05-30
CZ290208B6 (cs) 2002-06-12
ID24506A (id) 2000-07-20
EP1001955B1 (de) 2001-10-17
SK862000A3 (en) 2000-07-11
MY118796A (en) 2005-01-31
PL338214A1 (en) 2000-10-09

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