DE69628257D1 - Fluoreszierende Verbindungen und deren Verwendung zum Messen von Reticulozyten - Google Patents

Fluoreszierende Verbindungen und deren Verwendung zum Messen von Reticulozyten

Info

Publication number
DE69628257D1
DE69628257D1 DE69628257T DE69628257T DE69628257D1 DE 69628257 D1 DE69628257 D1 DE 69628257D1 DE 69628257 T DE69628257 T DE 69628257T DE 69628257 T DE69628257 T DE 69628257T DE 69628257 D1 DE69628257 D1 DE 69628257D1
Authority
DE
Germany
Prior art keywords
fluorescent compounds
measuring reticulocytes
reticulocytes
measuring
fluorescent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69628257T
Other languages
English (en)
Other versions
DE69628257T2 (de
Inventor
Yasumasa Akai
Kiminori Miyazaki
Takashi Sakata
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sysmex Corp
Original Assignee
Sysmex Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sysmex Corp filed Critical Sysmex Corp
Publication of DE69628257D1 publication Critical patent/DE69628257D1/de
Application granted granted Critical
Publication of DE69628257T2 publication Critical patent/DE69628257T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1468—Optical investigation techniques, e.g. flow cytometry with spatial resolution of the texture or inner structure of the particle
    • G01N15/147—Optical investigation techniques, e.g. flow cytometry with spatial resolution of the texture or inner structure of the particle the analysis being performed on a sample stream
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B23/00—Methine or polymethine dyes, e.g. cyanine dyes
    • C09B23/02—Methine or polymethine dyes, e.g. cyanine dyes the polymethine chain containing an odd number of >CH- or >C[alkyl]- groups
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/80—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood groups or blood types or red blood cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/01—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials specially adapted for biological cells, e.g. blood cells
    • G01N2015/012—Red blood cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/01—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials specially adapted for biological cells, e.g. blood cells
    • G01N2015/012—Red blood cells
    • G01N2015/014—Reticulocytes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/01—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials specially adapted for biological cells, e.g. blood cells
    • G01N2015/018—Platelets
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N2015/1477—Multiparameters
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N2015/1486—Counting the particles
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/80—Fluorescent dyes, e.g. rhodamine
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • Y10T436/101666—Particle count or volume standard or control [e.g., platelet count standards, etc.]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • Y10T436/107497—Preparation composition [e.g., lysing or precipitation, etc.]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • Y10T436/108331—Preservative, buffer, anticoagulant or diluent

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Organic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
DE69628257T 1995-10-06 1996-10-04 Fluoreszierende Verbindungen und deren Verwendung zum Messen von Reticulozyten Expired - Lifetime DE69628257T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP26034695A JP3425830B2 (ja) 1995-10-06 1995-10-06 新規化合物とその用途

Publications (2)

Publication Number Publication Date
DE69628257D1 true DE69628257D1 (de) 2003-06-26
DE69628257T2 DE69628257T2 (de) 2004-01-29

Family

ID=17346700

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69628257T Expired - Lifetime DE69628257T2 (de) 1995-10-06 1996-10-04 Fluoreszierende Verbindungen und deren Verwendung zum Messen von Reticulozyten

Country Status (7)

Country Link
US (1) US5821127A (de)
EP (1) EP0767382B1 (de)
JP (1) JP3425830B2 (de)
KR (1) KR100463129B1 (de)
CN (1) CN1083839C (de)
DE (1) DE69628257T2 (de)
TW (1) TW438795B (de)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW379284B (en) * 1996-04-12 2000-01-11 Toa Medical Electronics Agent for detecting reticulocyte
JP3783808B2 (ja) * 1997-05-19 2006-06-07 シスメックス株式会社 白血球分類計数用試薬
JP3886271B2 (ja) * 1998-11-27 2007-02-28 シスメックス株式会社 赤芽球の分類計数用試薬及び分類計数方法
JP2001238216A (ja) * 2000-02-23 2001-08-31 Matsushita Electric Ind Co Ltd 動画像圧縮装置および動画像圧縮方法
US6368864B1 (en) 2000-05-05 2002-04-09 Coulter International Corp. Dyes and methods of reticulocyte enumeration
US7405082B2 (en) * 2002-09-10 2008-07-29 Sysmex Corporation Methods and devices for measuring reticulocytes
JP4484442B2 (ja) 2003-04-10 2010-06-16 シスメックス株式会社 細菌測定方法と装置とプログラム
JP2005024472A (ja) * 2003-07-04 2005-01-27 Sysmex Corp 幼若血小板測定装置
JP4417143B2 (ja) * 2004-03-11 2010-02-17 シスメックス株式会社 試料分析装置、プログラムおよびそのプログラムを記録した記録媒体
JP4794414B2 (ja) * 2006-10-30 2011-10-19 シスメックス株式会社 血小板測定用試薬、血小板測定用試薬キット並びに血小板測定方法
JP4806330B2 (ja) * 2006-10-30 2011-11-02 シスメックス株式会社 網状赤血球及び血小板測定用試薬、網状赤血球及び血小板測定用試薬キット並びに網状赤血球及び血小板測定方法
CN101231243B (zh) * 2007-01-24 2011-11-16 深圳迈瑞生物医疗电子股份有限公司 网织红细胞检测试剂及检测方法
CN101236158B (zh) * 2007-01-29 2011-11-16 深圳迈瑞生物医疗电子股份有限公司 网织红细胞检测方法及检测装置
CN101349644B (zh) 2007-07-20 2012-06-27 深圳迈瑞生物医疗电子股份有限公司 一种白细胞分类试剂和其使用方法
CN105440725A (zh) 2008-01-04 2016-03-30 深圳迈瑞生物医疗电子股份有限公司 不对称菁类荧光染料，组合物及在生物样品染色中的用途
US9081021B2 (en) * 2008-02-18 2015-07-14 Sysmex Corporation Platelet measurement reagent, platelet measurement reagent kit, and platelet measurement method
CN101602762B (zh) 2008-06-10 2013-10-16 深圳迈瑞生物医疗电子股份有限公司 不对称菁类化合物、其制备方法及应用
CN101726579B (zh) 2008-10-17 2014-06-18 深圳迈瑞生物医疗电子股份有限公司 血液检测试剂和方法
CN101750274B (zh) 2008-12-17 2014-06-25 深圳迈瑞生物医疗电子股份有限公司 白细胞分类计数试剂、试剂盒以及白细胞分类计数的方法
JP5355145B2 (ja) 2009-02-26 2013-11-27 シスメックス株式会社 試薬調製装置、検体測定装置および試薬調製方法
CN101988082B (zh) 2009-07-31 2015-04-08 深圳迈瑞生物医疗电子股份有限公司 白细胞分类计数试剂、试剂盒及其制备方法和白细胞分类计数的方法
JP5773644B2 (ja) * 2010-12-28 2015-09-02 日揮触媒化成株式会社 水素化処理触媒の再生方法
CN103385236A (zh) * 2013-07-23 2013-11-13 山西省农业科学院果树研究所 一种果园中趋避黑绒鳃金龟的方法
CN104749144A (zh) * 2013-12-31 2015-07-01 深圳迈瑞生物医疗电子股份有限公司 血细胞检测试剂及血细胞处理方法和识别方法
WO2016106688A1 (zh) * 2014-12-31 2016-07-07 深圳迈瑞生物医疗电子股份有限公司 一种有核红细胞报警方法、装置及流式细胞分析仪
CN108956431B (zh) * 2018-08-09 2021-04-30 苏州叠代生物科技有限公司 一种单采血小板制品中残留细胞的检测方法

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5772150A (en) * 1980-10-23 1982-05-06 Ishihara Sangyo Kaisha Ltd Electrophotographic sensitive material
JPS6179163A (ja) * 1984-09-26 1986-04-22 Toa Medical Electronics Co Ltd 血球測定用試薬
US4957870A (en) * 1985-11-01 1990-09-18 Becton, Dickinson And Company Detection of Reticulocytes, RNA and DNA
EP0226272B1 (de) * 1985-11-01 1991-03-06 Becton, Dickinson and Company Nachweis von Retikulozyten
JPS62153758A (ja) * 1985-12-27 1987-07-08 Toa Medical Electronics Co Ltd フロ−サイトメ−タによる網状赤血球測定方法
JPS6361622A (ja) * 1986-08-29 1988-03-17 Nissan Shatai Co Ltd 自動車用空調装置
US4937198A (en) * 1989-07-28 1990-06-26 Becton, Dickinson And Company Novel fluorescent dye
US5312921A (en) * 1990-03-14 1994-05-17 Regents Of The University Of California Dyes designed for high sensitivity detection of double-stranded DNA
US5284771A (en) * 1991-12-05 1994-02-08 Miles Inc. Reagent compositions and their use in sphering cells
US5360739A (en) * 1991-12-05 1994-11-01 Miles Inc. Methods for the identification and characterization of reticulocytes in whole blood
US5321130A (en) * 1992-02-10 1994-06-14 Molecular Probes, Inc. Unsymmetrical cyanine dyes with a cationic side chain
US5534416A (en) * 1993-04-13 1996-07-09 Molecular Probes, Inc. Fluorescent viability assay using cyclic-substituted unsymmetrical cyanine dyes
US5436134A (en) * 1993-04-13 1995-07-25 Molecular Probes, Inc. Cyclic-substituted unsymmetrical cyanine dyes
AU6830894A (en) * 1993-05-14 1994-12-12 Coulter Corporation Reticulocyte analyzing method and apparatus utilizing light scatter techniques
US5563070A (en) * 1993-05-28 1996-10-08 Omron Corporation Method of counting reticulocytes
JP3553691B2 (ja) * 1995-04-12 2004-08-11 シスメックス株式会社 網状赤血球測定用試薬及び測定方法

Also Published As

Publication number Publication date
JP3425830B2 (ja) 2003-07-14
EP0767382A2 (de) 1997-04-09
CN1083839C (zh) 2002-05-01
EP0767382A3 (de) 1998-02-25
EP0767382B1 (de) 2003-05-21
KR100463129B1 (ko) 2005-07-01
DE69628257T2 (de) 2004-01-29
KR970021075A (ko) 1997-05-28
CN1154966A (zh) 1997-07-23
US5821127A (en) 1998-10-13
JPH09104683A (ja) 1997-04-22
TW438795B (en) 2001-06-07

Similar Documents

Publication Publication Date Title
DE69628257T2 (de) Fluoreszierende Verbindungen und deren Verwendung zum Messen von Reticulozyten
DE69627831D1 (de) Benzopyran-enthaltende verbindungen und verfahren zu deren verwendung
DE69833399D1 (de) Vorrichtung zum Messen der Konzentration von NOx
DE69414896D1 (de) Rasterabtastmikroskop und dessen Verwendung zum Vermessen von Oberflächen
DE59408401D1 (de) Polymerisierbare chirale verbindungen und deren verwendung
DE69620613D1 (de) System zum vermessen von bildern
DE69419291D1 (de) Formmessapparat
FI955511A0 (fi) Menetelmä fysikaalisten suureiden havaitsemiseksi ja/tai mittaamiseksi käyttäen hajautettua tunnistinta
FI951139A (fi) Menetelmä ja laite vaihe-eron mittaamiseksi
DE59601159D1 (de) Verfahren zum gegenseitigen ausrichten von körpern und lagemesssonde hierfür
DE69533910D1 (de) Messfühlersystem und Messverfahren
DE69430152D1 (de) Verfahren und Vorrichtung zum Messen von Glukoseverwandten Substanzen
DE69629640D1 (de) NOx-Sensor und Messverfahren dazu
FI924716A0 (fi) Menetelmä ja laitteisto näytteen analysoimiseksi
DE69329963D1 (de) Verbindungen für Fluoreszenzpolarisationsimmunoassays und Verwendung derselben in Immunoassays
DE69733590D1 (de) Reagenz zum Messen von Retikulozyten und Verfahren zu deren Messung
DE69635620D1 (de) Lichtquelle und messmethode
DE69632097D1 (de) Messapparat und -verfahren mit zwei zugeordneten Interferometern
NO973279D0 (no) PIK-beslektede kinasematerialer og fremgangsmåter for cellesykluskontrollpunkt
FI963253A0 (fi) Mittausjärjestely jauhimia varten
FI972172A (fi) Menetelmä kaasupitoisuuden mittaamiseksi ja kaasupitoisuusmittari
DE69028495D1 (de) Fühler für ionisierbare Substanzen
DE69620213D1 (de) [(3-alkoxy-phenoxy)-ethyl]-dialkylaminderivate und deren verwendung als lokalanaesthetika
DE68912477D1 (de) Verfahren zum messen der biologischen wirkung von antithrombin iii und reagenzien zu dessen messung.
DE69119791D1 (de) Hochempfindliche Bestimmungsmethode für L-Carnitin und Zusammensetzung für einen Reagenziensatz

Legal Events

Date Code Title Description
8364 No opposition during term of opposition