US5916891A
(en)
|
1992-01-13 |
1999-06-29 |
Smithkline Beecham Corporation |
Pyrimidinyl imidazoles
|
ES2053401B1
(es)
*
|
1992-01-13 |
1995-03-01 |
Smithkline Beecham Corp |
Compuestos de imidazol y procedimientos para su prepacion.
|
IL110296A
(en)
*
|
1993-07-16 |
1999-12-31 |
Smithkline Beecham Corp |
Imidazole compounds process for their preparation and pharmaceutical compositions containing them
|
US5593992A
(en)
*
|
1993-07-16 |
1997-01-14 |
Smithkline Beecham Corporation |
Compounds
|
US5783664A
(en)
*
|
1993-09-17 |
1998-07-21 |
Smithkline Beecham Corporation |
Cytokine suppressive anit-inflammatory drug binding proteins
|
US5922751A
(en)
*
|
1994-06-24 |
1999-07-13 |
Euro-Celtique, S.A. |
Aryl pyrazole compound for inhibiting phosphodiesterase IV and methods of using same
|
EP0797575B1
(de)
*
|
1994-12-13 |
2003-10-15 |
F. Hoffmann-La Roche Ag |
Imidazol derivate mit proteinkinase, insbesondere egf-r tyrosinkinase, inhibierender wirkung
|
NZ302117A
(en)
*
|
1995-01-12 |
1999-10-28 |
Smithkline Beecham Corp |
1-cycloalkyl or cycloalkylalkyl 4,5-trisubstituted imidazole derivatives and medicaments
|
US5700826A
(en)
*
|
1995-06-07 |
1997-12-23 |
Ontogen Corporation |
1,2,4,5-tetra substituted imidazoles as modulators of multi-drug resistance
|
AU6709596A
(en)
|
1995-08-22 |
1997-03-19 |
Japan Tobacco Inc. |
Amide compounds and use of the same
|
US5717100A
(en)
*
|
1995-10-06 |
1998-02-10 |
Merck & Co., Inc. |
Substituted imidazoles having anti-cancer and cytokine inhibitory activity
|
JP3382951B2
(ja)
*
|
1995-10-06 |
2003-03-04 |
メルク エンド カムパニー インコーポレーテッド |
抗がん活性及びサイトカン阻害活性を有する置換イミダゾール
|
US6083949A
(en)
*
|
1995-10-06 |
2000-07-04 |
Merck & Co., Inc. |
Substituted imidazoles having anti-cancer and cytokine inhibitory activity
|
AU702887B2
(en)
*
|
1995-10-31 |
1999-03-11 |
Merck & Co., Inc. |
Substituted pyridyl pyrroles, compositions containing such compounds and methods of use
|
ZA9610687B
(en)
*
|
1995-12-22 |
1997-09-29 |
Smithkline Beecham Corp |
Novel synthesis.
|
US6046208A
(en)
*
|
1996-01-11 |
2000-04-04 |
Smithkline Beecham Corporation |
Substituted imidazole compounds
|
AP9700912A0
(en)
|
1996-01-11 |
1997-01-31 |
Smithkline Beecham Corp |
Novel cycloalkyl substituted imidazoles
|
US5977103A
(en)
*
|
1996-01-11 |
1999-11-02 |
Smithkline Beecham Corporation |
Substituted imidazole compounds
|
EP1005343A4
(de)
*
|
1996-03-08 |
2000-06-07 |
Smithkline Beecham Corp |
Verwendung von csaids als inhibitoren der angiogenese
|
US6096748A
(en)
*
|
1996-03-13 |
2000-08-01 |
Smithkline Beecham Corporation |
Pyrimidine compounds useful in treating cytokine mediated diseases
|
US6235760B1
(en)
|
1996-03-25 |
2001-05-22 |
Smithkline Beecham Corporation |
Treatment for CNS injuries
|
EP0889888A4
(de)
*
|
1996-03-25 |
2003-01-08 |
Smithkline Beecham Corp |
Behandlung von verletzungen des zentralen nervensystems
|
US6294541B1
(en)
|
1996-06-06 |
2001-09-25 |
Euro-Celtique S.A. |
Purine derivatives having phosphodiesterase IV inhibition activity
|
JP3418624B2
(ja)
*
|
1996-06-10 |
2003-06-23 |
メルク エンド カンパニー インコーポレーテッド |
サイトカイン阻害活性を有する置換イミダゾール類
|
WO1998007425A1
(en)
|
1996-08-21 |
1998-02-26 |
Smithkline Beecham Corporation |
Imidazole compounds, compositions and use
|
US5744473A
(en)
*
|
1996-09-16 |
1998-04-28 |
Euro-Celtique, S.A. |
PDE IV inhibitors: "bis-compounds"
|
DE69728688T2
(de)
|
1996-11-19 |
2004-08-19 |
Amgen Inc., Thousand Oaks |
Aryl und heteroaryl substituierte kondensierte pyrrole als entzündunghemmende mittel
|
EP0959885A4
(de)
*
|
1996-11-20 |
2002-07-17 |
Merck & Co Inc |
Triaryl substituierte imidazole und verfahren zur verwendung
|
WO1998022109A1
(en)
*
|
1996-11-20 |
1998-05-28 |
Merck & Co., Inc. |
Triaryl substituted imidazoles as glucagon antagonists
|
AU728760B2
(en)
*
|
1996-11-20 |
2001-01-18 |
Merck & Co., Inc. |
Triaryl substituted imidazoles, compositions containing such compounds and methods of use
|
US5880139A
(en)
*
|
1996-11-20 |
1999-03-09 |
Merck & Co., Inc. |
Triaryl substituted imidazoles as glucagon antagonists
|
US6410729B1
(en)
|
1996-12-05 |
2002-06-25 |
Amgen Inc. |
Substituted pyrimidine compounds and methods of use
|
US6096753A
(en)
*
|
1996-12-05 |
2000-08-01 |
Amgen Inc. |
Substituted pyrimidinone and pyridone compounds and methods of use
|
US5929076A
(en)
*
|
1997-01-10 |
1999-07-27 |
Smithkline Beecham Corporation |
Cycloalkyl substituted imidazoles
|
EP1028954B1
(de)
*
|
1997-04-24 |
2003-07-02 |
Ortho-McNeil Pharmaceutical, Inc. |
Substituierte imidazole zur behandlung von entzündlichen krankheiten
|
PL199893B1
(pl)
*
|
1997-06-12 |
2008-11-28 |
Rhone Poulenc Rorer Ltd |
Imidazolilo-cykliczne acetale, kompozycja farmaceutyczna oraz zastosowanie imidazolilo-cyklicznych acetali
|
JP2002504909A
(ja)
|
1997-06-13 |
2002-02-12 |
スミスクライン・ビーチャム・コーポレイション |
新規な置換ピラゾールおよびピラゾリン化合物
|
US6610695B1
(en)
|
1997-06-19 |
2003-08-26 |
Smithkline Beecham Corporation |
Aryloxy substituted pyrimidine imidazole compounds
|
GB9713726D0
(en)
|
1997-06-30 |
1997-09-03 |
Ciba Geigy Ag |
Organic compounds
|
KR20010014288A
(ko)
*
|
1997-06-30 |
2001-02-26 |
오르토-맥네일 파마슈티칼, 인코퍼레이티드 |
염증성 질환의 치료에 유용한 2-치환된 이미다졸
|
US7301021B2
(en)
|
1997-07-02 |
2007-11-27 |
Smithkline Beecham Corporation |
Substituted imidazole compounds
|
AU8381098A
(en)
|
1997-07-02 |
1999-01-25 |
Smithkline Beecham Corporation |
Novel cycloalkyl substituted imidazoles
|
TW517055B
(en)
|
1997-07-02 |
2003-01-11 |
Smithkline Beecham Corp |
Novel substituted imidazole compounds
|
US6562832B1
(en)
|
1997-07-02 |
2003-05-13 |
Smithkline Beecham Corporation |
Substituted imidazole compounds
|
US6489325B1
(en)
|
1998-07-01 |
2002-12-03 |
Smithkline Beecham Corporation |
Substituted imidazole compounds
|
US5840721A
(en)
*
|
1997-07-09 |
1998-11-24 |
Ontogen Corporation |
Imidazole derivatives as MDR modulators
|
JP2001518507A
(ja)
|
1997-10-08 |
2001-10-16 |
スミスクライン・ビーチャム・コーポレイション |
新規シクロアルケニル置換化合物
|
US6022884A
(en)
|
1997-11-07 |
2000-02-08 |
Amgen Inc. |
Substituted pyridine compounds and methods of use
|
WO1999025697A1
(fr)
|
1997-11-19 |
1999-05-27 |
Kowa Co., Ltd. |
Nouveaux derives de pyridazine et medicaments contenant ces composes comme principe actif
|
BR9815170A
(pt)
|
1997-12-12 |
2000-10-10 |
Euro Celtique S A Luxembourg |
"método de obter composto aplicável no tratamento de asma em mamìferos"
|
US6335340B1
(en)
|
1997-12-19 |
2002-01-01 |
Smithkline Beecham Corporation |
compounds of heteroaryl substituted imidazole, their pharmaceutical compositons and uses
|
JP4570777B2
(ja)
*
|
1998-02-26 |
2010-10-27 |
オーソ−マクニール・フアーマシユーチカル・インコーポレーテツド |
炎症性疾患を処置するための置換されたピロロベンゾイミダゾール
|
BR9910621A
(pt)
|
1998-05-22 |
2001-01-30 |
Smithkline Beecham Corp |
Novos compostos de imidazol 2-alquil substituìdos
|
US6858617B2
(en)
|
1998-05-26 |
2005-02-22 |
Smithkline Beecham Corporation |
Substituted imidazole compounds
|
WO1999067283A2
(en)
*
|
1998-06-24 |
1999-12-29 |
University Of Dundee |
Two-kinase domain mitogen- and stress-activated protein kinases and uses thereof
|
AU4395399A
(en)
*
|
1998-07-02 |
2000-01-24 |
Sankyo Company Limited |
Five-membered heteroaryl compounds
|
ES2221426T3
(es)
|
1998-08-20 |
2004-12-16 |
Smithkline Beecham Corporation |
Nuevos compuestos de triazol sustituidos.
|
EP1112275B9
(de)
|
1998-09-09 |
2004-03-10 |
Metabasis Therapeutics, Inc. |
Neue heteroaromatische fructose 1,6-bisphosphatase inhibitoren
|
DE19842833B4
(de)
*
|
1998-09-18 |
2005-04-14 |
Merckle Gmbh |
2-Arylalkylthio-imidazole, 2-Arylalkenylthio-imidazole und 2-Arylalkinylthio-imidazole als Entzündungs-Hemmstoffe und Hemmstoffe der Cytokin-Freisetzung
|
ATE258055T1
(de)
|
1998-11-04 |
2004-02-15 |
Smithkline Beecham Corp |
Pyridin-4-yl oder pyrimidin-4-yl substituierte pyrazine
|
US6319928B1
(en)
|
1998-11-30 |
2001-11-20 |
Euro-Celtique, S.A. |
Purine derivatives having phosphodiesterase IV inhibition activity
|
US6239279B1
(en)
*
|
1998-12-16 |
2001-05-29 |
Smithkline Beecham Corporation |
Synthesis for 4-aryl-5-pyrimidine imidazole substituted derivatives
|
JP2002534385A
(ja)
|
1999-01-08 |
2002-10-15 |
スミスクライン・ビーチャム・コーポレイション |
新規化合物
|
UA73492C2
(en)
*
|
1999-01-19 |
2005-08-15 |
|
Aromatic heterocyclic compounds as antiinflammatory agents
|
EP1157026A1
(de)
|
1999-02-22 |
2001-11-28 |
Boehringer Ingelheim Pharmaceuticals Inc. |
Polyheterocyclische verbindungen mit entzündungshemmender wirkung
|
JP2000247959A
(ja)
|
1999-02-26 |
2000-09-12 |
Kowa Co |
ピリダジン−3−オン誘導体及びこれを含有する医薬
|
ES2251360T3
(es)
|
1999-03-12 |
2006-05-01 |
Boehringer Ingelheim Pharmaceuticals Inc. |
Compuestos heterociclicos aromaticos en calidad de agentes antiinflamatorios.
|
EE04799B1
(et)
|
1999-03-12 |
2007-04-16 |
Boehringer Ingelheim Pharmaceuticals, Inc. |
Ühendid, mis on kasulikud põletikuvastaste vahenditena, nende ühendite valmistamise meetodid ja neid sisaldavad farmatseutilised kompositsioonid
|
WO2000059449A2
(en)
|
1999-04-02 |
2000-10-12 |
Euro-Celtique S.A. |
Purine derivatives having phosphodiesterase iv inhibition activity
|
AU4315100A
(en)
*
|
1999-04-28 |
2000-11-17 |
Sankyo Company Limited |
Preventive or inhibitory agents for hepatopathy
|
CA2374559A1
(en)
|
1999-05-14 |
2000-11-23 |
Ortho-Mcneil Pharmaceutical, Inc. |
Substituted 3-pyridyl-4-arylpyrroles, and related therapeutic and prophylactic methods
|
ES2253233T3
(es)
*
|
1999-07-09 |
2006-06-01 |
Boehringer Ingelheim Pharmaceuticals Inc. |
Procedimiento para sintesis de compuestos de urea heteroaril sustituidos.
|
SK9892001A3
(en)
|
1999-11-10 |
2002-04-04 |
Ortho Mcneil Pharm Inc |
Substituted 2-aryl-3-(heteroaryl)-imidazo[1,2-a]pyrimidines, and related pharmaceutical compositions and methods
|
US6808902B1
(en)
|
1999-11-12 |
2004-10-26 |
Amgen Inc. |
Process for correction of a disulfide misfold in IL-1Ra Fc fusion molecules
|
ATE281439T1
(de)
|
1999-11-23 |
2004-11-15 |
Smithkline Beecham Corp |
3,4-dihydro-(1h)chinazolin-2-on-verbindungen als csbp/p38-kinase-inhibitoren
|
US6759410B1
(en)
|
1999-11-23 |
2004-07-06 |
Smithline Beecham Corporation |
3,4-dihydro-(1H)-quinazolin-2-ones and their use as CSBP/p38 kinase inhibitors
|
US7053098B1
(en)
|
1999-11-23 |
2006-05-30 |
Smithkline Beecham Corporation |
3,4-Dihydro-(1H) quinazolin-2-one compounds as CSBP/P38 kinase inhibitors
|
JP2003528043A
(ja)
|
1999-11-23 |
2003-09-24 |
スミスクライン・ビーチャム・コーポレイション |
CSBP/p38キナーゼ阻害剤としての3,4‐ジヒドロ−(1H)キナゾリン−2−オン化合物
|
US6525046B1
(en)
|
2000-01-18 |
2003-02-25 |
Boehringer Ingelheim Pharmaceuticals, Inc. |
Aromatic heterocyclic compounds as antiinflammatory agents
|
US6608052B2
(en)
|
2000-02-16 |
2003-08-19 |
Boehringer Ingelheim Pharmaceuticals, Inc. |
Compounds useful as anti-inflammatory agents
|
AR029803A1
(es)
*
|
2000-02-21 |
2003-07-16 |
Smithkline Beecham Plc |
Imidazoles sustituidos con piridilo y composiciones farmaceuticas que las comprenden
|
US7235551B2
(en)
|
2000-03-02 |
2007-06-26 |
Smithkline Beecham Corporation |
1,5-disubstituted-3,4-dihydro-1h-pyrimido[4,5-d]pyrimidin-2-one compounds and their use in treating csbp/p38 kinase mediated diseases
|
GB0007405D0
(en)
*
|
2000-03-27 |
2000-05-17 |
Smithkline Beecham Corp |
Compounds
|
EP1268474A2
(de)
*
|
2000-03-30 |
2003-01-02 |
Takeda Chemical Industries, Ltd. |
Substituierte 1,3-thiazol-verbindungen, ihre herstellung und verwendung
|
US7563774B2
(en)
|
2000-06-29 |
2009-07-21 |
Metabasis Therapeutics, Inc. |
Combination of FBPase inhibitors and antidiabetic agents useful for the treatment of diabetes
|
US6664256B1
(en)
|
2000-07-10 |
2003-12-16 |
Kowa Co., Ltd. |
Phenylpyridazine compounds and medicines containing the same
|
DE60111417T2
(de)
|
2000-10-18 |
2006-03-16 |
Ortho-Mcneil Pharmaceutical, Inc. |
Substituierte imidazole, die sich für die behandlung entzündlicher krankheiten eignen
|
CA2426654C
(en)
|
2000-10-23 |
2010-12-21 |
Smithkline Beecham Corporation |
2,4,8-trisubstituted-8h-pyrido[2,3-d}pyrimidin-7-one compounds
|
CA2436739A1
(en)
*
|
2000-12-26 |
2002-07-04 |
Takeda Chemical Industries, Ltd. |
Combination agent
|
WO2002057265A1
(fr)
|
2001-01-22 |
2002-07-25 |
Sankyo Company, Limited |
Composes substitues avec des groupes amines bicycliques
|
DE10107683A1
(de)
|
2001-02-19 |
2002-08-29 |
Merckle Gmbh Chem Pharm Fabrik |
2-Thio-substituierte Imidazolderivate und ihre Verwendung in der Pharmazie
|
US6790846B2
(en)
|
2001-05-24 |
2004-09-14 |
The Procter & Gamble Company |
Isoxazolone compounds useful in treating diseases associated with unwanted cytokine activity
|
PL222211B1
(pl)
|
2001-06-26 |
2016-07-29 |
Amgen Fremont Inc |
Przeciwciało przeciwko OPGL, kompozycja je zawierająca, jego zastosowanie i sposób jego wytwarzania, sposób wykrywania poziomu OPGL, kompozycja obejmująca polinukleotydy i komórka gosodarza
|
US20030118575A1
(en)
*
|
2001-12-11 |
2003-06-26 |
Boehringer Ingelheim Pharmaceuticals, Inc. |
Method for administering BIRB 796 BS
|
WO2003072569A1
(en)
*
|
2002-02-25 |
2003-09-04 |
Boehringer Ingelheim Pharmaceuticals, Inc. |
1,4-disubstituted benzofused cycloalkyl urea compounds useful in treating cytokine mediated diseases
|
WO2003080179A1
(fr)
|
2002-03-27 |
2003-10-02 |
Nippon Sigmax Co., Ltd. |
Dispositif de regulation de cytokines, dispositif de traitement et procede de traitement
|
AR039241A1
(es)
|
2002-04-04 |
2005-02-16 |
Biogen Inc |
Heteroarilos trisustituidos y metodos para su produccion y uso de los mismos
|
EP1534282B1
(de)
|
2002-07-09 |
2006-12-27 |
Boehringer Ingelheim Pharma GmbH & Co.KG |
Pharazeutische zusammensetzungen aus anticholinergica und p38 kinase hemmern zur behandlung von erkrankungen der atemwege
|
EP1554272B1
(de)
*
|
2002-08-09 |
2006-10-25 |
Eli Lilly And Company |
Benzimidazole und benzothiazole als inhibitoren der map-kinase
|
ES2497116T3
(es)
|
2002-08-19 |
2014-09-22 |
Lorus Therapeutics Inc. |
Imidazoles 2,4,5-trisustituidos y su uso como agentes antimicrobianos
|
DE10238045A1
(de)
|
2002-08-20 |
2004-03-04 |
Merckle Gmbh Chem.-Pharm. Fabrik |
2-Thio-substituierte Imidazolderivate und ihre Verwendung in der Pharmazie
|
UA80295C2
(en)
|
2002-09-06 |
2007-09-10 |
Biogen Inc |
Pyrazolopyridines and using the same
|
WO2004060911A2
(en)
|
2002-12-30 |
2004-07-22 |
Amgen Inc. |
Combination therapy with co-stimulatory factors
|
WO2004063192A1
(en)
*
|
2003-01-10 |
2004-07-29 |
Pharmacopeia Drug Discovery, Inc. |
Imidazolyl pyrimidine derivatives useful as il-8 receptor modulators
|
CL2004000234A1
(es)
*
|
2003-02-12 |
2005-04-15 |
Biogen Idec Inc |
Compuestos derivados 3-(piridin-2-il)-4-heteroaril-pirazol sustituidos, antagonistas de aik5 y/o aik4; composicion farmaceutica y uso del compuesto en el tratamiento de desordenes fibroticos como esclerodermia, lupus nefritico, cicatrizacion de herid
|
CL2004000366A1
(es)
*
|
2003-02-26 |
2005-01-07 |
Pharmacia Corp Sa Organizada B |
USO DE UNA COMBINACION DE UN COMPUESTO DERIVADO DE PIRAZOL INHIBIDOR DE QUINASA p38, Y UN INHIBIDOR DE ACE PARA TRATAR DISFUNCION RENAL, ENFERMEDAD CARDIOVASCULAR Y VASCULAR, RETINOPATIA, NEUROPATIA, EDEMA, DISFUNCION ENDOTELIAL O INSULINOPATIA.
|
WO2004083188A1
(ja)
|
2003-03-18 |
2004-09-30 |
Kowa Co., Ltd. |
水溶性フェニルピリダジン誘導体及びこれを含有する医薬
|
AU2004289539C1
(en)
|
2003-11-14 |
2012-06-07 |
Lorus Therapeutics Inc. |
Aryl imidazoles and their use as anti-cancer agents
|
TW200529845A
(en)
*
|
2003-12-12 |
2005-09-16 |
Wyeth Corp |
Quinolines useful in treating cardiovascular disease
|
WO2005063247A1
(en)
*
|
2003-12-22 |
2005-07-14 |
Amgen Inc. |
Aryl sulfonamide compounds and uses related thereto
|
TWI332003B
(en)
*
|
2004-01-30 |
2010-10-21 |
Lilly Co Eli |
Kinase inhibitors
|
US20060035893A1
(en)
|
2004-08-07 |
2006-02-16 |
Boehringer Ingelheim International Gmbh |
Pharmaceutical compositions for treatment of respiratory and gastrointestinal disorders
|
JP2008520744A
(ja)
|
2004-11-19 |
2008-06-19 |
ザ・レジェンツ・オブ・ザ・ユニバーシティ・オブ・カリフォルニア |
抗炎症性ピラゾロピリミジン
|
US20080119498A1
(en)
*
|
2004-12-06 |
2008-05-22 |
Masatomo Kato |
Therapeutic Agent for Pruritus Comprising P38 Map Kinase Inhibitor as the Active Ingredient
|
PE20060777A1
(es)
|
2004-12-24 |
2006-10-06 |
Boehringer Ingelheim Int |
Derivados de indolinona para el tratamiento o la prevencion de enfermedades fibroticas
|
EP1832584B1
(de)
|
2004-12-28 |
2011-12-21 |
ASKA Pharmaceutical Co., Ltd. |
Pyrimidinylisoxazolderivat
|
KR101327323B1
(ko)
*
|
2005-01-14 |
2013-11-11 |
에스케이바이오팜 주식회사 |
옥사졸 하이드록삼산 유도체 및 이들의 용도
|
PE20061351A1
(es)
|
2005-03-25 |
2007-01-14 |
Glaxo Group Ltd |
COMPUESTOS 8H-PIRIDO[2,3-d]PIRIMIDIN-7-ONA 2,4,8-TRISUSTITUIDOS COMO INHIBIDORES DE LA QUINASA CSBP/RK/p38
|
US8148392B2
(en)
|
2005-05-25 |
2012-04-03 |
Lorus Therapeutics Inc. |
2-indolyl imidazo [4,5-d] phenanthroline derivatives and their use in the treatment of cancer
|
TW200804288A
(en)
*
|
2005-12-12 |
2008-01-16 |
Astrazeneca Ab |
Alkylsulphonamide quinolines
|
CA2647391C
(en)
|
2006-04-04 |
2015-12-29 |
The Regents Of The University Of California |
Kinase antagonists
|
AU2007265964A1
(en)
|
2006-06-28 |
2008-01-03 |
Aska Pharmaceutical Co., Ltd. |
Treatment agent for inflammatory bowel disease
|
KR101412943B1
(ko)
|
2006-06-28 |
2014-06-26 |
아스카 세이야쿠 가부시키가이샤 |
피리딜이소옥사졸 유도체
|
KR101434706B1
(ko)
*
|
2007-02-16 |
2014-08-26 |
아스카 세이야쿠 가부시키가이샤 |
미립자 유성 현탁액을 포함하는 의약 조성물
|
WO2008133192A1
(ja)
*
|
2007-04-19 |
2008-11-06 |
Takeda Pharmaceutical Company Limited |
縮合イミダゾール化合物およびその用途
|
EP1992344A1
(de)
|
2007-05-18 |
2008-11-19 |
Institut Curie |
P38 Alpha als therapeutisches Target für Erkrankungen, die mit einer FGFR3- Mutation assoziiert sind
|
WO2009046448A1
(en)
|
2007-10-04 |
2009-04-09 |
Intellikine, Inc. |
Chemical entities and therapeutic uses thereof
|
US8703777B2
(en)
|
2008-01-04 |
2014-04-22 |
Intellikine Llc |
Certain chemical entities, compositions and methods
|
US8193182B2
(en)
|
2008-01-04 |
2012-06-05 |
Intellikine, Inc. |
Substituted isoquinolin-1(2H)-ones, and methods of use thereof
|
US8993580B2
(en)
|
2008-03-14 |
2015-03-31 |
Intellikine Llc |
Benzothiazole kinase inhibitors and methods of use
|
US8637542B2
(en)
|
2008-03-14 |
2014-01-28 |
Intellikine, Inc. |
Kinase inhibitors and methods of use
|
WO2010006072A2
(en)
|
2008-07-08 |
2010-01-14 |
The Regents Of The University Of California |
Mtor modulators and uses thereof
|
WO2010006086A2
(en)
|
2008-07-08 |
2010-01-14 |
Intellikine, Inc. |
Kinase inhibitors and methods of use
|
CA2738429C
(en)
|
2008-09-26 |
2016-10-25 |
Intellikine, Inc. |
Heterocyclic kinase inhibitors
|
EP2358720B1
(de)
|
2008-10-16 |
2016-03-02 |
The Regents of The University of California |
Heteroarylkinasehemmer mit kondensierten ringen
|
US8476431B2
(en)
|
2008-11-03 |
2013-07-02 |
Itellikine LLC |
Benzoxazole kinase inhibitors and methods of use
|
US8691866B2
(en)
|
2008-12-10 |
2014-04-08 |
The General Hospital Corporation |
HIF inhibitors and use thereof
|
JP5789252B2
(ja)
|
2009-05-07 |
2015-10-07 |
インテリカイン, エルエルシー |
複素環式化合物およびその使用
|
ES2634470T3
(es)
|
2009-09-30 |
2017-09-27 |
Toray Industries, Inc. |
Derivado de 2,3-dihidro-1H-inden-2-ilurea y aplicación farmacéutica del mismo
|
US8980899B2
(en)
|
2009-10-16 |
2015-03-17 |
The Regents Of The University Of California |
Methods of inhibiting Ire1
|
JP5951600B2
(ja)
|
2010-05-21 |
2016-07-13 |
インフィニティー ファーマシューティカルズ, インコーポレイテッド |
キナーゼ調節のための、化合物、組成物および方法
|
CA2817577A1
(en)
|
2010-11-10 |
2012-05-18 |
Infinity Pharmaceuticals, Inc. |
Heterocyclic compounds and uses thereof
|
US8809349B2
(en)
|
2011-01-10 |
2014-08-19 |
Infinity Pharmaceuticals, Inc. |
Processes for preparing isoquinolinones and solid forms of isoquinolinones
|
TWI592411B
(zh)
|
2011-02-23 |
2017-07-21 |
英特爾立秦有限責任公司 |
激酶抑制劑之組合及其用途
|
US20140163075A1
(en)
*
|
2011-06-01 |
2014-06-12 |
Netherland Cancer Institute |
Modulation of the ubiquitin-proteasome system (ups)
|
AU2012284088B2
(en)
|
2011-07-19 |
2015-10-08 |
Infinity Pharmaceuticals Inc. |
Heterocyclic compounds and uses thereof
|
AR088218A1
(es)
|
2011-07-19 |
2014-05-21 |
Infinity Pharmaceuticals Inc |
Compuestos heterociclicos utiles como inhibidores de pi3k
|
EP2751093A1
(de)
|
2011-08-29 |
2014-07-09 |
Infinity Pharmaceuticals, Inc. |
Heterocyclische verbindungen und ihre verwendung
|
JP6342805B2
(ja)
|
2011-09-02 |
2018-06-13 |
ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア |
置換ピラゾロ[3,4−d]ピリミジンおよびその用途
|
EP2793880A4
(de)
*
|
2011-12-23 |
2015-06-24 |
Millennium Pharm Inc |
Heteroaryle und verwendungen davon
|
ES2897740T3
(es)
|
2011-12-28 |
2022-03-02 |
Kyoto Prefectural Public Univ Corp |
Normalización del cultivo de células endoteliales de la córnea
|
US8940742B2
(en)
|
2012-04-10 |
2015-01-27 |
Infinity Pharmaceuticals, Inc. |
Heterocyclic compounds and uses thereof
|
US8828998B2
(en)
|
2012-06-25 |
2014-09-09 |
Infinity Pharmaceuticals, Inc. |
Treatment of lupus, fibrotic conditions, and inflammatory myopathies and other disorders using PI3 kinase inhibitors
|
BR112015006828A8
(pt)
|
2012-09-26 |
2019-09-17 |
Univ California |
composto, ou um sal farmaceuticamente aceitável do mesmo; composição farmacêutica; uso do composto; e método para modular a atividade de uma proteína ire1
|
US9481667B2
(en)
|
2013-03-15 |
2016-11-01 |
Infinity Pharmaceuticals, Inc. |
Salts and solid forms of isoquinolinones and composition comprising and methods of using the same
|
JP2016516082A
(ja)
|
2013-03-20 |
2016-06-02 |
アプトース バイオサイエンシーズ, インコーポレイテッド |
2−置換イミダゾ[4,5−d]フェナントロリン誘導体及び癌の治療におけるそれらの使用
|
EP2986293A1
(de)
|
2013-04-19 |
2016-02-24 |
Astrazeneca AB |
Nk3-rezeptorantagonistverbindung (nk3rai zur verwendung in einem verfahren für die behandlung von polyzystischem ovarialsyndrom (pcos)
|
PE20160685A1
(es)
|
2013-10-04 |
2016-07-23 |
Infinity Pharmaceuticals Inc |
Compuestos heterociclicos y usos de los mismos
|
DK3052102T3
(da)
|
2013-10-04 |
2020-03-09 |
Aptose Biosciences Inc |
Sammensætninger til behandling af cancere
|
US9751888B2
(en)
|
2013-10-04 |
2017-09-05 |
Infinity Pharmaceuticals, Inc. |
Heterocyclic compounds and uses thereof
|
EP3069732B1
(de)
|
2013-11-14 |
2023-07-12 |
The Doshisha |
Arzneimittel zur behandlung des hornhautendothels durch förderung der zellproliferation oder hemmung von zellschäden
|
SG10201808053XA
(en)
|
2014-03-19 |
2018-10-30 |
Infinity Pharmaceuticals Inc |
Heterocyclic compounds for use in the treatment of pi3k-gamma mediated disorders
|
WO2015160975A2
(en)
|
2014-04-16 |
2015-10-22 |
Infinity Pharmaceuticals, Inc. |
Combination therapies
|
US9708348B2
(en)
|
2014-10-03 |
2017-07-18 |
Infinity Pharmaceuticals, Inc. |
Trisubstituted bicyclic heterocyclic compounds with kinase activities and uses thereof
|
WO2016210292A1
(en)
|
2015-06-25 |
2016-12-29 |
Children's Medical Center Corporation |
Methods and compositions relating to hematopoietic stem cell expansion, enrichment, and maintenance
|
WO2017048702A1
(en)
|
2015-09-14 |
2017-03-23 |
Infinity Pharmaceuticals, Inc. |
Solid forms of isoquinolinone derivatives, process of making, compositions comprising, and methods of using the same
|
EP3429603B1
(de)
|
2016-03-15 |
2021-12-29 |
Children's Medical Center Corporation |
Verfahren und zusammensetzungen im zusammenhang mit der expansion hämatopoetischer stammzellen
|
WO2017161116A1
(en)
|
2016-03-17 |
2017-09-21 |
Infinity Pharmaceuticals, Inc. |
Isotopologues of isoquinolinone and quinazolinone compounds and uses thereof as pi3k kinase inhibitors
|
WO2017214269A1
(en)
|
2016-06-08 |
2017-12-14 |
Infinity Pharmaceuticals, Inc. |
Heterocyclic compounds and uses thereof
|
CN109640999A
(zh)
|
2016-06-24 |
2019-04-16 |
无限药品股份有限公司 |
组合疗法
|
FR3060987B1
(fr)
*
|
2016-12-22 |
2020-10-02 |
Oreal |
Procede de coloration des fibres keratiniques mettant en oeuvre au moins un colorant triarylmethane particulier et au moins un colorant fluorescent
|
KR20200096914A
(ko)
|
2017-10-30 |
2020-08-14 |
압토스 바이오사이언시스 인코포레이티드 |
암 치료용 아릴 이미다졸
|